Motif ID: Emx1_Emx2

Z-value: 0.726

Transcription factors associated with Emx1_Emx2:

Gene SymbolEntrez IDGene Name
Emx1 ENSMUSG00000033726.8 Emx1
Emx2 ENSMUSG00000043969.4 Emx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Emx2mm10_v2_chr19_+_59458372_59458450-0.381.2e-01Click!
Emx1mm10_v2_chr6_+_85187438_85187510-0.048.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Emx1_Emx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_90969768 1.125 ENSMUST00000181184.1
4930544I03Rik
RIKEN cDNA 4930544I03 gene
chr4_-_82505749 1.124 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr10_+_90071095 1.097 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_+_81257277 0.993 ENSMUST00000117488.1
ENSMUST00000105328.3
ENSMUST00000121205.1
Matk


megakaryocyte-associated tyrosine kinase


chr7_+_126781483 0.955 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr4_-_82505274 0.922 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr10_-_53647080 0.789 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr7_-_142661858 0.753 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr4_-_82505707 0.705 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr17_-_36032682 0.679 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr10_-_86011833 0.633 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr8_-_21906412 0.590 ENSMUST00000051965.4
Defb11
defensin beta 11
chr3_+_121953213 0.530 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr17_+_45734506 0.523 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr13_-_97747373 0.520 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr6_+_79818031 0.500 ENSMUST00000179797.1
Gm20594
predicted gene, 20594
chr10_-_88605017 0.482 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr8_+_34054622 0.480 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr7_-_5413145 0.473 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr4_-_155645408 0.466 ENSMUST00000115821.2
Gm10563
predicted gene 10563
chr8_+_85432686 0.455 ENSMUST00000180883.1
1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr16_-_26371828 0.448 ENSMUST00000023154.2
Cldn1
claudin 1
chr14_+_26259109 0.433 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr7_-_103827922 0.431 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chrX_+_8271133 0.429 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr18_-_34579072 0.428 ENSMUST00000079287.5
Nme5
NME/NM23 family member 5
chr9_-_20728219 0.415 ENSMUST00000034692.7
Olfm2
olfactomedin 2
chr11_+_109543694 0.390 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr14_+_25979401 0.380 ENSMUST00000173580.1
Duxbl1
double homeobox B-like 1
chr2_+_36230426 0.377 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr3_+_137341103 0.370 ENSMUST00000119475.1
Emcn
endomucin
chr14_+_26119173 0.355 ENSMUST00000174564.1
Duxbl2
doubl homeobox B-like 2
chr14_+_26258786 0.355 ENSMUST00000172517.1
Duxbl3
double homeobox B-like 3
chr6_-_57535422 0.339 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr2_+_110597298 0.338 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr14_+_26119811 0.329 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr9_+_72958785 0.318 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr4_-_150914401 0.308 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chr14_+_25980039 0.307 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr8_-_8690493 0.307 ENSMUST00000048545.8
Arglu1
arginine and glutamate rich 1
chr13_+_23763660 0.305 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chr4_-_64276595 0.301 ENSMUST00000141162.1
Gm11217
predicted gene 11217
chr10_+_102158858 0.297 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chrX_+_106920618 0.285 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr1_-_40085823 0.282 ENSMUST00000181756.1
Gm16894
predicted gene, 16894
chr12_-_87444017 0.272 ENSMUST00000091090.4
2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr16_-_97170707 0.271 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr5_+_135009152 0.266 ENSMUST00000111216.1
ENSMUST00000046999.8
Abhd11

abhydrolase domain containing 11

chr1_+_93685574 0.261 ENSMUST00000027499.6
Bok
BCL2-related ovarian killer protein
chr6_-_129533267 0.250 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr11_-_42000284 0.246 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr3_+_121531603 0.241 ENSMUST00000180804.1
A530020G20Rik
RIKEN cDNA A530020G20 gene
chr13_+_16014457 0.241 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr13_+_23555023 0.238 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr3_+_137341067 0.237 ENSMUST00000122064.1
Emcn
endomucin
chr2_+_175372436 0.232 ENSMUST00000131676.1
ENSMUST00000109048.2
ENSMUST00000109047.2
Gm4723


predicted gene 4723


chr17_-_48432723 0.231 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr2_-_175703646 0.230 ENSMUST00000109027.2
ENSMUST00000179061.1
ENSMUST00000131041.1
Gm4245


predicted gene 4245


chr12_+_109545390 0.223 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr12_-_84617326 0.217 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr4_+_102589687 0.216 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr18_-_6241486 0.214 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chr5_-_28210022 0.214 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr14_-_96519067 0.212 ENSMUST00000022666.7
Klhl1
kelch-like 1
chr3_+_88716838 0.212 ENSMUST00000029692.8
ENSMUST00000171645.1
Rit1

Ras-like without CAAX 1

chr6_+_42245907 0.212 ENSMUST00000031897.5
Gstk1
glutathione S-transferase kappa 1
chr4_+_118961578 0.211 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr12_+_36314160 0.210 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr4_+_147492417 0.207 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr2_+_175469985 0.199 ENSMUST00000109042.3
ENSMUST00000109002.2
ENSMUST00000109043.2
ENSMUST00000143490.1
Gm8923



predicted gene 8923



chr4_+_145510759 0.195 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225

chr17_-_47043039 0.193 ENSMUST00000075152.5
Gm4945
predicted gene 4945
chr8_+_72219726 0.191 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr2_-_157566319 0.190 ENSMUST00000109528.2
ENSMUST00000088494.2
Blcap

bladder cancer associated protein homolog (human)

chr7_+_110772604 0.180 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr3_-_130730375 0.176 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr15_+_99295087 0.175 ENSMUST00000128352.1
ENSMUST00000145482.1
Prpf40b

PRP40 pre-mRNA processing factor 40 homolog B (yeast)

chr2_-_73580288 0.170 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr18_-_15403680 0.166 ENSMUST00000079081.6
Aqp4
aquaporin 4
chr3_+_88716884 0.165 ENSMUST00000172252.1
Rit1
Ras-like without CAAX 1
chr13_-_97747399 0.165 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr14_+_55560010 0.160 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr17_+_46772635 0.159 ENSMUST00000071430.5
2310039H08Rik
RIKEN cDNA 2310039H08 gene
chr10_+_128322443 0.158 ENSMUST00000026446.2
Cnpy2
canopy 2 homolog (zebrafish)
chr8_+_69300776 0.158 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr10_-_49783259 0.150 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr1_+_32172711 0.147 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr3_+_90541146 0.145 ENSMUST00000107333.1
ENSMUST00000107331.1
ENSMUST00000098910.2
S100a16


S100 calcium binding protein A16


chr14_+_58893465 0.145 ENSMUST00000079960.1
Rpl13-ps3
ribosomal protein L13, pseudogene 3
chr17_-_31636631 0.144 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
Cbs


cystathionine beta-synthase


chr14_+_53324632 0.138 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr1_-_158356258 0.138 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr8_-_85432841 0.136 ENSMUST00000047749.5
4921524J17Rik
RIKEN cDNA 4921524J17 gene
chr9_-_124304718 0.134 ENSMUST00000071300.6
2010315B03Rik
RIKEN cDNA 2010315B03 gene
chr12_-_56345862 0.130 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr4_-_134245579 0.129 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr2_-_12419387 0.129 ENSMUST00000124515.1
Fam188a
family with sequence similarity 188, member A
chr2_-_5676046 0.128 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr7_-_97738222 0.127 ENSMUST00000084986.6
Aqp11
aquaporin 11
chr10_+_79996479 0.126 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr1_+_63176818 0.122 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr4_+_126609818 0.119 ENSMUST00000097886.3
ENSMUST00000164362.1
5730409E04Rik

RIKEN cDNA 5730409E04Rik gene

chr9_+_34904913 0.118 ENSMUST00000045091.6
Kirrel3
kin of IRRE like 3 (Drosophila)
chr6_-_89595647 0.118 ENSMUST00000032172.8
ENSMUST00000113550.3
Chchd6

coiled-coil-helix-coiled-coil-helix domain containing 6

chr8_+_31089471 0.112 ENSMUST00000036631.7
ENSMUST00000170204.1
Dusp26

dual specificity phosphatase 26 (putative)

chr6_+_129533183 0.108 ENSMUST00000032264.6
Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr9_-_53667429 0.106 ENSMUST00000166367.1
ENSMUST00000034529.7
Cul5

cullin 5

chr7_+_132610620 0.105 ENSMUST00000033241.5
Lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr10_+_69787431 0.103 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr3_-_146495115 0.103 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr2_+_151494182 0.100 ENSMUST00000089140.6
Nsfl1c
NSFL1 (p97) cofactor (p47)
chr18_-_43477764 0.098 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr9_-_15301555 0.098 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr16_+_21794320 0.098 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr4_+_110397661 0.096 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr8_-_107588392 0.090 ENSMUST00000044106.4
Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr7_-_84679346 0.089 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr2_+_144594054 0.087 ENSMUST00000136628.1
Gm561
predicted gene 561
chr2_-_37647199 0.086 ENSMUST00000028279.3
Strbp
spermatid perinuclear RNA binding protein
chr1_-_133610253 0.081 ENSMUST00000166915.1
Snrpe
small nuclear ribonucleoprotein E
chr2_-_34826071 0.078 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr14_-_15438974 0.077 ENSMUST00000055211.4
Lrrc3b
leucine rich repeat containing 3B
chr11_+_5788480 0.076 ENSMUST00000109845.1
ENSMUST00000020769.7
ENSMUST00000102928.4
Dbnl


drebrin-like


chr2_-_34826187 0.075 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
Fbxw2


F-box and WD-40 domain protein 2


chr2_+_30171486 0.073 ENSMUST00000015481.5
Endog
endonuclease G
chr10_+_52022502 0.072 ENSMUST00000163017.1
ENSMUST00000058347.4
Vgll2

vestigial like 2 homolog (Drosophila)

chr4_+_83417715 0.072 ENSMUST00000030206.3
ENSMUST00000071544.4
Snapc3

small nuclear RNA activating complex, polypeptide 3

chr8_+_93810832 0.071 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr5_-_139345149 0.069 ENSMUST00000049630.6
Cox19
cytochrome c oxidase assembly protein 19
chrX_-_150814265 0.068 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr7_-_125491397 0.065 ENSMUST00000138616.1
Nsmce1
non-SMC element 1 homolog (S. cerevisiae)
chr7_+_78783119 0.065 ENSMUST00000032840.4
Mrps11
mitochondrial ribosomal protein S11
chr17_+_29274078 0.063 ENSMUST00000149405.2
BC004004
cDNA sequence BC004004
chr15_+_99006056 0.061 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr6_-_144209448 0.060 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr6_-_144209558 0.059 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr6_+_66896480 0.058 ENSMUST00000114222.1
Gng12
guanine nucleotide binding protein (G protein), gamma 12
chr3_+_103171655 0.057 ENSMUST00000005830.8
Bcas2
breast carcinoma amplified sequence 2
chr6_+_17749170 0.057 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr9_+_14500611 0.053 ENSMUST00000004200.8
Cwc15
CWC15 homolog (S. cerevisiae)
chr4_+_110397764 0.052 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chr1_-_184999549 0.052 ENSMUST00000027929.4
Mark1
MAP/microtubule affinity-regulating kinase 1
chr13_-_23934156 0.051 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr12_+_87443896 0.049 ENSMUST00000161023.1
ENSMUST00000160488.1
ENSMUST00000077462.7
ENSMUST00000160880.1
Slirp



SRA stem-loop interacting RNA binding protein



chr3_+_108571699 0.047 ENSMUST00000143054.1
Taf13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr12_-_87388317 0.043 ENSMUST00000021424.4
Sptlc2
serine palmitoyltransferase, long chain base subunit 2
chr2_-_12419456 0.042 ENSMUST00000154899.1
ENSMUST00000028105.6
Fam188a

family with sequence similarity 188, member A

chr11_+_17257558 0.042 ENSMUST00000000594.2
ENSMUST00000156784.1
C1d

C1D nuclear receptor co-repressor

chr3_+_32436376 0.041 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr17_-_56036546 0.041 ENSMUST00000003268.9
Sh3gl1
SH3-domain GRB2-like 1
chrX_-_134111852 0.039 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr5_-_118244861 0.039 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr6_-_144209471 0.038 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chrM_+_2743 0.038 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr3_-_151749877 0.036 ENSMUST00000029671.7
Ifi44
interferon-induced protein 44
chr3_+_32436151 0.033 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr1_+_163779575 0.033 ENSMUST00000027877.6
ENSMUST00000077642.5
Kifap3

kinesin-associated protein 3

chr2_-_160619971 0.031 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr14_-_18893376 0.027 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr6_+_124304646 0.026 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr2_+_119047129 0.025 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chrX_-_102505359 0.025 ENSMUST00000087916.4
Hdac8
histone deacetylase 8
chr13_-_92030897 0.024 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr1_-_144177259 0.022 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr9_+_108648720 0.022 ENSMUST00000098384.2
Gm10621
predicted gene 10621
chr3_+_106034661 0.021 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chrX_-_74393003 0.018 ENSMUST00000015427.6
Fam3a
family with sequence similarity 3, member A
chr4_+_41966058 0.018 ENSMUST00000108026.2
Gm20938
predicted gene, 20938
chr2_-_155930190 0.017 ENSMUST00000109636.4
ENSMUST00000109631.1
Uqcc1

ubiquinol-cytochrome c reductase complex assembly factor 1

chr15_-_102510681 0.017 ENSMUST00000171565.1
Map3k12
mitogen-activated protein kinase kinase kinase 12
chr6_+_37870786 0.015 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr7_-_19573343 0.014 ENSMUST00000051364.3
Gemin7
gem (nuclear organelle) associated protein 7
chr2_-_67194695 0.012 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr14_+_46832127 0.011 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr16_-_16829276 0.011 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr7_-_101845300 0.008 ENSMUST00000094141.5
Folr2
folate receptor 2 (fetal)
chr13_-_106847267 0.005 ENSMUST00000057427.4
Lrrc70
leucine rich repeat containing 70
chr10_+_81183000 0.004 ENSMUST00000178422.1
Dapk3
death-associated protein kinase 3
chr7_+_43672003 0.004 ENSMUST00000038332.8
Ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr15_+_85510812 0.002 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr3_+_146852359 0.001 ENSMUST00000038090.5
ENSMUST00000170055.1
Ttll7

tubulin tyrosine ligase-like family, member 7


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.7 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.4 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 1.0 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.3 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.1 0.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.4 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 1.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.3 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 0.3 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 0.1 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.0 0.2 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.3 GO:0036159 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.2 GO:0008356 asymmetric cell division(GO:0008356) asymmetric neuroblast division(GO:0055059) asymmetric stem cell division(GO:0098722)
0.0 0.1 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 1.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.0 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.2 GO:0043512 inhibin A complex(GO:0043512)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.1 0.3 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 2.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.6 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.0 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.4 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage