Motif ID: Epas1_Bcl3

Z-value: 2.152

Transcription factors associated with Epas1_Bcl3:

Gene SymbolEntrez IDGene Name
Bcl3 ENSMUSG00000053175.10 Bcl3
Epas1 ENSMUSG00000024140.9 Epas1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Epas1mm10_v2_chr17_+_86753900_867539140.691.7e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Epas1_Bcl3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_48045144 11.046 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr10_+_127725392 10.850 ENSMUST00000026466.3
Tac2
tachykinin 2
chr8_-_48555846 10.629 ENSMUST00000110345.1
ENSMUST00000110343.1
Tenm3

teneurin transmembrane protein 3

chr3_-_80802789 9.863 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr14_-_60177482 9.727 ENSMUST00000140924.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr9_-_40346290 7.983 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr12_-_14152038 7.779 ENSMUST00000020926.6
Fam84a
family with sequence similarity 84, member A
chr2_+_4300462 7.327 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr12_-_67221221 6.301 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr2_-_113217051 6.273 ENSMUST00000080673.5
Ryr3
ryanodine receptor 3
chr17_+_86167777 6.145 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr9_-_29963112 5.995 ENSMUST00000075069.4
Ntm
neurotrimin
chr4_-_20778527 5.981 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr17_+_48932368 5.815 ENSMUST00000046254.2
Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
chr19_+_8664005 5.374 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr7_-_27446599 5.313 ENSMUST00000011895.7
Sptbn4
spectrin beta, non-erythrocytic 4
chr16_-_38713235 5.063 ENSMUST00000023487.4
Arhgap31
Rho GTPase activating protein 31
chr1_+_75507077 4.919 ENSMUST00000037330.4
Inha
inhibin alpha
chr3_-_127225847 4.856 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr15_+_81936911 4.730 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr4_-_46991842 4.599 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr7_+_99535652 4.566 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr4_+_17853451 4.511 ENSMUST00000029881.3
Mmp16
matrix metallopeptidase 16
chr15_+_82275197 4.492 ENSMUST00000116423.1
Sept3
septin 3
chr19_+_23758819 4.342 ENSMUST00000025830.7
Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr4_+_123183722 4.258 ENSMUST00000152194.1
Hpcal4
hippocalcin-like 4
chr2_-_52676571 4.227 ENSMUST00000178799.1
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr3_-_108017806 4.106 ENSMUST00000126593.1
Gstm1
glutathione S-transferase, mu 1
chr10_+_106470281 3.756 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr10_+_42860348 3.721 ENSMUST00000063063.7
Scml4
sex comb on midleg-like 4 (Drosophila)
chr11_-_101785252 3.696 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr15_-_66969616 3.589 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
Ndrg1



N-myc downstream regulated gene 1



chr9_+_26733728 3.536 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr6_-_142964404 3.435 ENSMUST00000032421.3
St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr13_+_16014457 3.248 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr2_-_66410064 3.239 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr3_+_28263563 3.220 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
Tnik






TRAF2 and NCK interacting kinase






chr6_-_84593810 3.097 ENSMUST00000077705.3
ENSMUST00000168003.2
Cyp26b1

cytochrome P450, family 26, subfamily b, polypeptide 1

chr8_+_3587445 2.923 ENSMUST00000057028.7
ENSMUST00000171962.1
Camsap3

calmodulin regulated spectrin-associated protein family, member 3

chr7_+_122671378 2.874 ENSMUST00000182563.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr1_+_66321708 2.838 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr7_+_99535439 2.803 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr19_+_6400523 2.797 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr3_-_82145865 2.788 ENSMUST00000048976.6
Gucy1a3
guanylate cyclase 1, soluble, alpha 3
chr6_-_112947246 2.770 ENSMUST00000088373.4
Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr13_-_45964964 2.737 ENSMUST00000180110.1
ENSMUST00000091628.3
ENSMUST00000167708.2
Atxn1


ataxin 1


chr18_-_25753852 2.710 ENSMUST00000025117.6
ENSMUST00000115816.2
Celf4

CUGBP, Elav-like family member 4

chr7_+_122671401 2.655 ENSMUST00000182095.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr10_+_42860776 2.652 ENSMUST00000105494.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr10_+_127420334 2.607 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr8_+_110721462 2.586 ENSMUST00000052457.8
Mtss1l
metastasis suppressor 1-like
chr1_+_152399824 2.549 ENSMUST00000044311.8
Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr9_+_89909775 2.453 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chrX_+_69360294 2.441 ENSMUST00000033532.6
Aff2
AF4/FMR2 family, member 2
chr5_+_27261916 2.383 ENSMUST00000101471.3
Dpp6
dipeptidylpeptidase 6
chr5_+_81021202 2.380 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr10_-_42276688 2.377 ENSMUST00000175881.1
ENSMUST00000056974.3
Foxo3

forkhead box O3

chr18_+_22345089 2.368 ENSMUST00000120223.1
ENSMUST00000097655.3
Asxl3

additional sex combs like 3 (Drosophila)

chr6_-_29179584 2.301 ENSMUST00000159200.1
Prrt4
proline-rich transmembrane protein 4
chr12_+_61523889 2.299 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr3_-_127225917 2.286 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr5_-_9725305 2.280 ENSMUST00000004076.3
Grm3
glutamate receptor, metabotropic 3
chr8_+_82863351 2.274 ENSMUST00000078525.5
Rnf150
ring finger protein 150
chr17_-_29237759 2.235 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr9_+_103008479 2.201 ENSMUST00000035148.6
Slco2a1
solute carrier organic anion transporter family, member 2a1
chr5_-_67847400 2.131 ENSMUST00000113652.1
ENSMUST00000113651.1
ENSMUST00000037380.8
Atp8a1


ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1


chr2_+_169632996 2.122 ENSMUST00000109159.2
Tshz2
teashirt zinc finger family member 2
chr2_-_113758638 2.108 ENSMUST00000099575.3
Grem1
gremlin 1
chr5_+_35757875 2.100 ENSMUST00000101280.3
ENSMUST00000054598.5
ENSMUST00000114205.1
ENSMUST00000114206.2
Ablim2



actin-binding LIM protein 2



chr1_+_66322102 2.085 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr7_-_140082489 2.083 ENSMUST00000026541.7
Caly
calcyon neuron-specific vesicular protein
chr6_-_124768330 2.079 ENSMUST00000135626.1
Eno2
enolase 2, gamma neuronal
chr15_+_81936753 2.055 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr8_-_84800344 2.054 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr5_-_30461902 2.048 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
Otof



otoferlin



chr14_-_76556662 2.045 ENSMUST00000064517.7
Serp2
stress-associated endoplasmic reticulum protein family member 2
chr2_+_156421083 2.041 ENSMUST00000125153.2
ENSMUST00000103136.1
ENSMUST00000109577.2
Epb4.1l1


erythrocyte protein band 4.1-like 1


chr5_-_128953303 2.032 ENSMUST00000111346.1
Rimbp2
RIMS binding protein 2
chr7_+_96210107 2.014 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr9_-_50739365 1.998 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr7_+_121392266 1.987 ENSMUST00000084628.3
Hs3st2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr13_-_96132568 1.986 ENSMUST00000161263.1
Sv2c
synaptic vesicle glycoprotein 2c
chr4_-_120747248 1.976 ENSMUST00000030376.7
Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr5_+_81021583 1.976 ENSMUST00000121707.1
Lphn3
latrophilin 3
chr2_+_136713444 1.972 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25

chr11_+_96251100 1.968 ENSMUST00000129907.2
Gm53
predicted gene 53
chr1_-_132542934 1.957 ENSMUST00000086521.4
Cntn2
contactin 2
chr4_+_139923349 1.934 ENSMUST00000128563.1
Gm13028
predicted gene 13028
chr4_-_141598206 1.908 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr2_+_68861564 1.900 ENSMUST00000176018.1
Cers6
ceramide synthase 6
chr18_-_77565050 1.894 ENSMUST00000182153.1
ENSMUST00000182146.1
ENSMUST00000026494.7
ENSMUST00000182024.1
Rnf165



ring finger protein 165



chr17_+_8525369 1.818 ENSMUST00000115715.1
Pde10a
phosphodiesterase 10A
chr9_-_44234014 1.789 ENSMUST00000037644.6
Cbl
Casitas B-lineage lymphoma
chr4_+_13743424 1.781 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_153345809 1.754 ENSMUST00000109790.1
Asxl1
additional sex combs like 1
chr12_+_95692212 1.738 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr1_+_59912972 1.736 ENSMUST00000036540.5
Fam117b
family with sequence similarity 117, member B
chr5_-_25498702 1.728 ENSMUST00000173073.1
ENSMUST00000045291.7
Kmt2c

lysine (K)-specific methyltransferase 2C

chr2_+_156421048 1.706 ENSMUST00000109574.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr4_-_88033328 1.706 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr7_+_129257027 1.702 ENSMUST00000094018.4
Ppapdc1a
phosphatidic acid phosphatase type 2 domain containing 1A
chr3_-_107760221 1.691 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr15_-_77307043 1.689 ENSMUST00000048145.5
ENSMUST00000171751.1
Rbfox2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr5_-_25498748 1.675 ENSMUST00000173174.1
Kmt2c
lysine (K)-specific methyltransferase 2C
chr6_-_112946754 1.670 ENSMUST00000113169.2
Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr3_-_89160155 1.664 ENSMUST00000029686.3
Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr6_+_136954521 1.657 ENSMUST00000137768.1
Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr11_+_69095217 1.651 ENSMUST00000101004.2
Per1
period circadian clock 1
chr11_-_72207413 1.634 ENSMUST00000108505.1
4933427D14Rik
RIKEN cDNA 4933427D14 gene
chr7_-_31054815 1.598 ENSMUST00000071697.4
ENSMUST00000108110.3
Fxyd1

FXYD domain-containing ion transport regulator 1

chr13_-_92131494 1.592 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr7_+_110768169 1.586 ENSMUST00000170374.1
Ampd3
adenosine monophosphate deaminase 3
chr14_+_84443553 1.581 ENSMUST00000071370.5
Pcdh17
protocadherin 17
chr13_+_42052015 1.558 ENSMUST00000060148.5
Hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr15_-_78718113 1.548 ENSMUST00000088592.4
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr5_+_130448801 1.503 ENSMUST00000111288.2
Caln1
calneuron 1
chr17_+_8849974 1.471 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr19_+_27217011 1.470 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr8_+_118283719 1.468 ENSMUST00000117160.1
Cdh13
cadherin 13
chr11_+_97798995 1.460 ENSMUST00000143571.1
Lasp1
LIM and SH3 protein 1
chr7_-_119184374 1.443 ENSMUST00000084650.4
Gpr139
G protein-coupled receptor 139
chr17_-_32788284 1.438 ENSMUST00000159086.2
Zfp871
zinc finger protein 871
chr11_+_97450136 1.431 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr15_-_37458523 1.418 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr5_-_8622855 1.414 ENSMUST00000047485.8
ENSMUST00000115378.1
Rundc3b

RUN domain containing 3B

chr13_+_94083490 1.408 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr2_+_55437100 1.393 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr11_+_98348404 1.393 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_-_78578308 1.374 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr2_-_104493690 1.374 ENSMUST00000111124.1
Hipk3
homeodomain interacting protein kinase 3
chr9_+_20868628 1.373 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr13_+_58807884 1.370 ENSMUST00000079828.5
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr15_+_57694651 1.362 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr4_-_20778852 1.352 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chr7_+_29859966 1.350 ENSMUST00000074876.6
ENSMUST00000057652.6
Zfp420

zinc finger protein 420

chr10_-_128645784 1.333 ENSMUST00000065334.3
Ikzf4
IKAROS family zinc finger 4
chr5_-_67847360 1.324 ENSMUST00000072971.6
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr11_-_97575210 1.311 ENSMUST00000107596.2
Srcin1
SRC kinase signaling inhibitor 1
chr2_-_63184253 1.291 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr10_-_11082287 1.290 ENSMUST00000105561.2
ENSMUST00000044306.6
Grm1

glutamate receptor, metabotropic 1

chr6_+_128399766 1.290 ENSMUST00000001561.5
Nrip2
nuclear receptor interacting protein 2
chr9_+_21196705 1.280 ENSMUST00000003395.9
Pde4a
phosphodiesterase 4A, cAMP specific
chr10_+_18469958 1.280 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr3_+_96596628 1.274 ENSMUST00000058943.7
Ankrd34a
ankyrin repeat domain 34A
chr13_+_94358943 1.258 ENSMUST00000022196.3
Ap3b1
adaptor-related protein complex 3, beta 1 subunit
chr14_-_70630149 1.249 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chr7_+_3303643 1.231 ENSMUST00000172109.1
Prkcg
protein kinase C, gamma
chr7_+_110772604 1.229 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr11_-_116359060 1.210 ENSMUST00000149147.1
Rnf157
ring finger protein 157
chr10_+_42860648 1.206 ENSMUST00000105495.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr19_+_27217357 1.205 ENSMUST00000047645.6
ENSMUST00000167487.1
Vldlr

very low density lipoprotein receptor

chrX_-_7947763 1.201 ENSMUST00000154244.1
Hdac6
histone deacetylase 6
chr19_-_50678642 1.181 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr10_-_32890462 1.164 ENSMUST00000092602.1
Nkain2
Na+/K+ transporting ATPase interacting 2
chr11_-_76468396 1.149 ENSMUST00000065028.7
Abr
active BCR-related gene
chr18_-_80713062 1.147 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr6_+_8949670 1.131 ENSMUST00000060369.3
Nxph1
neurexophilin 1
chr19_+_26748268 1.116 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr3_-_108085346 1.114 ENSMUST00000078912.5
Ampd2
adenosine monophosphate deaminase 2
chr3_+_156561792 1.105 ENSMUST00000074015.4
Negr1
neuronal growth regulator 1
chr15_+_84680974 1.093 ENSMUST00000065499.4
Prr5
proline rich 5 (renal)
chr6_+_48739039 1.079 ENSMUST00000054368.4
ENSMUST00000140054.1
Gimap1

GTPase, IMAP family member 1

chr1_-_9299238 1.070 ENSMUST00000140295.1
Sntg1
syntrophin, gamma 1
chr2_+_121358591 1.066 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr7_-_141539784 1.065 ENSMUST00000118694.1
ENSMUST00000153191.1
ENSMUST00000166082.1
ENSMUST00000026586.6
Chid1



chitinase domain containing 1



chr4_+_124880899 1.055 ENSMUST00000059343.6
Epha10
Eph receptor A10
chr9_-_50727921 0.987 ENSMUST00000118707.1
ENSMUST00000034566.8
Dixdc1

DIX domain containing 1

chr3_+_5218516 0.986 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr9_-_102354685 0.977 ENSMUST00000035129.7
ENSMUST00000085169.5
Ephb1

Eph receptor B1

chr5_-_144965793 0.960 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
Smurf1


SMAD specific E3 ubiquitin protein ligase 1


chr13_-_63565520 0.941 ENSMUST00000021921.5
Ptch1
patched homolog 1
chr17_+_85613432 0.937 ENSMUST00000176081.1
Six3
sine oculis-related homeobox 3
chr10_-_13868932 0.934 ENSMUST00000019942.5
ENSMUST00000162610.1
Aig1

androgen-induced 1

chr4_+_123183456 0.931 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr5_+_26904682 0.922 ENSMUST00000120555.1
Dpp6
dipeptidylpeptidase 6
chr4_-_126325641 0.908 ENSMUST00000131113.1
Tekt2
tektin 2
chr16_-_59553970 0.905 ENSMUST00000139989.1
Crybg3
beta-gamma crystallin domain containing 3
chr6_+_91684061 0.899 ENSMUST00000032185.7
Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr13_-_94358818 0.899 ENSMUST00000059598.2
Gm9776
predicted gene 9776
chr5_+_143651222 0.888 ENSMUST00000110727.1
Cyth3
cytohesin 3
chr15_+_80173642 0.873 ENSMUST00000044970.6
Mgat3
mannoside acetylglucosaminyltransferase 3
chr5_-_36695969 0.860 ENSMUST00000031091.9
ENSMUST00000140063.1
D5Ertd579e

DNA segment, Chr 5, ERATO Doi 579, expressed

chr10_-_13868779 0.859 ENSMUST00000105534.3
Aig1
androgen-induced 1
chr6_+_119175247 0.847 ENSMUST00000112777.2
ENSMUST00000073909.5
Dcp1b

DCP1 decapping enzyme homolog B (S. cerevisiae)

chr10_+_81628540 0.834 ENSMUST00000123896.1
Ankrd24
ankyrin repeat domain 24
chr8_-_46294592 0.813 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr3_+_105452326 0.812 ENSMUST00000098761.3
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr17_+_35135463 0.809 ENSMUST00000173535.1
ENSMUST00000173952.1
Bag6

BCL2-associated athanogene 6

chr2_-_103760922 0.807 ENSMUST00000140895.1
Nat10
N-acetyltransferase 10
chr4_+_125490688 0.806 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr18_+_65581704 0.798 ENSMUST00000182979.1
Zfp532
zinc finger protein 532
chr8_+_79028587 0.791 ENSMUST00000119254.1
Zfp827
zinc finger protein 827
chr5_+_13398688 0.790 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr7_+_131966446 0.784 ENSMUST00000045840.4
Gpr26
G protein-coupled receptor 26
chr5_-_73338580 0.781 ENSMUST00000087195.5
Ociad2
OCIA domain containing 2
chr2_+_130406478 0.776 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr5_+_134932351 0.773 ENSMUST00000047196.7
ENSMUST00000111221.2
ENSMUST00000111219.1
ENSMUST00000068617.5
ENSMUST00000111218.1
ENSMUST00000136246.1
Wbscr27





Williams Beuren syndrome chromosome region 27 (human)





chr11_+_69088490 0.750 ENSMUST00000021273.6
ENSMUST00000117780.1
Vamp2

vesicle-associated membrane protein 2

chrX_+_23693043 0.746 ENSMUST00000035766.6
ENSMUST00000101670.2
Wdr44

WD repeat domain 44

chr5_-_123140135 0.743 ENSMUST00000160099.1
AI480526
expressed sequence AI480526

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.0 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
2.7 10.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
1.9 13.2 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
1.6 12.6 GO:0097264 self proteolysis(GO:0097264)
1.5 6.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.4 8.2 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
1.2 7.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
1.0 3.1 GO:0098528 terpenoid catabolic process(GO:0016115) skeletal muscle fiber differentiation(GO:0098528)
0.9 5.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.9 4.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.8 7.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.8 7.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.8 3.8 GO:0002158 osteoclast proliferation(GO:0002158)
0.7 2.0 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
0.6 3.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.6 3.7 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.6 1.8 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.6 3.9 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.6 2.8 GO:0075136 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.5 2.7 GO:0034436 glycoprotein transport(GO:0034436)
0.5 2.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.5 1.0 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.5 2.4 GO:0035063 nuclear speck organization(GO:0035063)
0.5 2.9 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 1.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.5 6.9 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.5 1.4 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.4 3.1 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.4 0.9 GO:0009957 epidermal cell fate specification(GO:0009957)
0.4 1.3 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.4 1.2 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.4 2.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.4 1.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.4 3.6 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.4 0.7 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.4 1.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 0.7 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.3 2.7 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3 1.7 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.3 1.7 GO:0097167 circadian regulation of translation(GO:0097167)
0.3 3.6 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.3 1.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.3 1.0 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.3 1.9 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) regulation of inorganic anion transmembrane transport(GO:1903795)
0.3 0.9 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.3 4.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.3 8.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 3.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.3 1.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.3 4.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.2 1.2 GO:0032423 regulation of mismatch repair(GO:0032423)
0.2 4.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 1.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.2 1.4 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.2 0.7 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 2.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 4.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 0.8 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.2 0.6 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.2 1.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 0.2 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.2 5.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 9.6 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.2 8.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 0.7 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 3.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 3.4 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.2 0.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 1.3 GO:0097475 motor neuron migration(GO:0097475)
0.2 1.6 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.2 0.8 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.2 0.3 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 1.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 1.7 GO:0015732 prostaglandin transport(GO:0015732)
0.1 0.5 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 1.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.4 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 1.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.1 GO:0038203 TORC2 signaling(GO:0038203)
0.1 4.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 2.0 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 2.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.3 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.1 0.4 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.8 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 1.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 3.1 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.1 1.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 2.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.8 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.1 3.2 GO:0019228 neuronal action potential(GO:0019228)
0.1 1.7 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 0.9 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 8.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 0.2 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 1.3 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 2.6 GO:0097178 ruffle assembly(GO:0097178)
0.1 0.8 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.1 3.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 3.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.4 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605)
0.1 0.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.4 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 1.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.1 1.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.4 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 1.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 1.4 GO:0034340 response to type I interferon(GO:0034340)
0.1 3.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.9 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:1903756 regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 3.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.9 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:1904706 detection of oxygen(GO:0003032) negative regulation of macrophage cytokine production(GO:0010936) negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.8 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.4 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 3.7 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 2.1 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 1.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 3.3 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.2 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.7 GO:0008542 visual learning(GO:0008542)
0.0 1.1 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.1 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.4 GO:0006402 mRNA catabolic process(GO:0006402)
0.0 0.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.5 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0043512 inhibin A complex(GO:0043512)
1.3 6.3 GO:0030314 junctional membrane complex(GO:0030314)
1.1 4.5 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.9 4.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.9 5.3 GO:0008091 spectrin(GO:0008091)
0.7 15.2 GO:0032279 asymmetric synapse(GO:0032279)
0.7 2.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.6 2.9 GO:0036449 microtubule minus-end(GO:0036449)
0.6 1.7 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.5 4.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.5 7.4 GO:0031143 pseudopodium(GO:0031143)
0.4 1.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.4 1.7 GO:0044316 cone cell pedicle(GO:0044316)
0.3 1.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 7.1 GO:0031430 M band(GO:0031430)
0.3 3.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 2.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 2.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.7 GO:0043202 lysosomal lumen(GO:0043202)
0.2 3.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.3 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.2 2.7 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 2.3 GO:0097449 astrocyte projection(GO:0097449)
0.1 1.8 GO:0016600 flotillin complex(GO:0016600)
0.1 2.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 5.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.6 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.8 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.1 2.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 4.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 3.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 2.0 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.2 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 0.9 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 3.6 GO:0030315 T-tubule(GO:0030315)
0.1 1.0 GO:0032433 filopodium tip(GO:0032433)
0.1 1.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.1 GO:0071564 npBAF complex(GO:0071564)
0.1 4.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 7.1 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 5.7 GO:0043204 perikaryon(GO:0043204)
0.0 2.5 GO:0005901 caveola(GO:0005901)
0.0 6.4 GO:0030027 lamellipodium(GO:0030027)
0.0 4.6 GO:0043197 dendritic spine(GO:0043197)
0.0 8.7 GO:0000139 Golgi membrane(GO:0000139)
0.0 5.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.2 GO:0055037 recycling endosome(GO:0055037)
0.0 1.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.4 GO:0043679 axon terminus(GO:0043679)
0.0 19.6 GO:0045202 synapse(GO:0045202)
0.0 0.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 1.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0 1.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.9 GO:0001726 ruffle(GO:0001726)
0.0 0.8 GO:0030686 90S preribosome(GO:0030686)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.5 GO:0043209 myelin sheath(GO:0043209)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0036126 sperm flagellum(GO:0036126)
0.0 6.1 GO:0005768 endosome(GO:0005768)
0.0 0.4 GO:0042383 sarcolemma(GO:0042383)
0.0 0.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 6.7 GO:0097458 neuron part(GO:0097458)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
2.1 6.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
1.8 10.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.5 6.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.9 8.2 GO:0034711 inhibin binding(GO:0034711)
0.9 2.7 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.9 4.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.8 2.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.8 4.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.6 4.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.6 3.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.6 3.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.6 2.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.6 3.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 2.7 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.5 3.8 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.5 13.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.5 1.4 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.4 1.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 1.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.4 1.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.4 4.1 GO:0016151 nickel cation binding(GO:0016151)
0.4 1.1 GO:0004568 chitinase activity(GO:0004568)
0.3 2.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 3.0 GO:0034046 poly(G) binding(GO:0034046)
0.3 1.3 GO:0098988 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled glutamate receptor activity(GO:0098988) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.3 11.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 4.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 2.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 1.5 GO:0055100 adiponectin binding(GO:0055100)
0.3 2.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.3 0.9 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.3 1.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.1 GO:0004111 creatine kinase activity(GO:0004111)
0.2 3.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 13.7 GO:0030507 spectrin binding(GO:0030507)
0.2 3.1 GO:0001972 retinoic acid binding(GO:0001972)
0.2 2.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 2.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 2.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 5.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 1.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 4.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 2.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.2 3.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.2 6.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 3.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 1.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 0.7 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2 0.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 2.5 GO:0045499 chemorepellent activity(GO:0045499)
0.2 2.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.5 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.2 1.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 0.9 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.1 1.9 GO:0031005 filamin binding(GO:0031005)
0.1 7.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 4.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 2.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.0 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 2.5 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 1.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.9 GO:0030553 cGMP binding(GO:0030553)
0.1 0.7 GO:0005272 sodium channel activity(GO:0005272)
0.1 0.4 GO:0019863 IgE binding(GO:0019863)
0.1 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 3.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.1 4.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 5.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.3 GO:0031489 myosin V binding(GO:0031489)
0.1 1.0 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) primary miRNA binding(GO:0070878)
0.0 0.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.9 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 3.5 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.4 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 5.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0036004 GAF domain binding(GO:0036004)
0.0 5.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 9.0 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 1.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 3.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 16.5 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.4 11.0 ST_GA12_PATHWAY G alpha 12 Pathway
0.2 10.0 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.2 7.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.2 1.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.7 PID_CONE_PATHWAY Visual signal transduction: Cones
0.1 8.5 PID_LKB1_PATHWAY LKB1 signaling events
0.1 3.6 PID_ALK1_PATHWAY ALK1 signaling events
0.1 0.4 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 3.0 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.1 1.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 2.7 PID_SHP2_PATHWAY SHP2 signaling
0.1 3.8 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.8 PID_TNF_PATHWAY TNF receptor signaling pathway
0.1 2.0 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.4 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.1 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.0 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 3.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 1.2 PID_P73PATHWAY p73 transcription factor network
0.0 0.7 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.1 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.8 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID_FAS_PATHWAY FAS (CD95) signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 8.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.6 8.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.5 11.1 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.3 13.2 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.3 4.3 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 4.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.3 2.7 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 3.1 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 8.1 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 3.9 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.2 7.7 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 1.7 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.2 3.9 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 2.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 4.0 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 2.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.2 5.1 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 4.1 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 5.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.1 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 4.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 8.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 4.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 3.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.1 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.6 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.1 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 0.5 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.8 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.1 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 6.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.7 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.8 REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.0 1.4 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.2 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis