Motif ID: Esrrg

Z-value: 0.449


Transcription factors associated with Esrrg:

Gene SymbolEntrez IDGene Name
Esrrg ENSMUSG00000026610.7 Esrrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Esrrgmm10_v2_chr1_+_187609028_1876090470.253.1e-01Click!


Activity profile for motif Esrrg.

activity profile for motif Esrrg


Sorted Z-values histogram for motif Esrrg

Sorted Z-values for motif Esrrg



Network of associatons between targets according to the STRING database.



First level regulatory network of Esrrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 156 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_77185815 1.139 ENSMUST00000079618.4
 St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr7_-_37772868 1.134 ENSMUST00000176205.1
 Zfp536
zinc finger protein 536
chr15_+_25742314 1.033 ENSMUST00000135981.1
 Myo10
myosin X
chr18_+_57142782 0.995 ENSMUST00000139892.1
 Megf10
multiple EGF-like-domains 10
chr9_-_107668967 0.948 ENSMUST00000177567.1
 Slc38a3
solute carrier family 38, member 3
chr13_-_51567084 0.932 ENSMUST00000021898.5
 Shc3
src homology 2 domain-containing transforming protein C3
chr16_+_32608973 0.917 ENSMUST00000120680.1
 Tfrc
transferrin receptor
chr1_+_127204986 0.834 ENSMUST00000038361.4
 Mgat5
mannoside acetylglucosaminyltransferase 5
chr14_+_20929416 0.792 ENSMUST00000022369.7
 Vcl
vinculin
chr17_-_17624458 0.740 ENSMUST00000041047.2
 Lnpep
leucyl/cystinyl aminopeptidase
chr2_-_130839683 0.693 ENSMUST00000119422.1
 4930402H24Rik
RIKEN cDNA 4930402H24 gene
chr11_-_97573929 0.687 ENSMUST00000126287.1
ENSMUST00000107590.1
 Srcin1

SRC kinase signaling inhibitor 1

chr3_-_107517321 0.664 ENSMUST00000166892.1
 Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr4_-_63662910 0.661 ENSMUST00000184252.1
 Gm11214
predicted gene 11214
chr19_-_4334001 0.648 ENSMUST00000176653.1
 Kdm2a
lysine (K)-specific demethylase 2A
chr17_-_81649607 0.647 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
 Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr3_+_68869563 0.632 ENSMUST00000054551.2
 1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr14_+_78849171 0.626 ENSMUST00000040990.5
 Vwa8
von Willebrand factor A domain containing 8
chr16_+_10545390 0.603 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
 Clec16a


C-type lectin domain family 16, member A


chr4_-_126202583 0.569 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
 Thrap3


thyroid hormone receptor associated protein 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.1 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.2 1.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 1.0 GO:0043654 skeletal muscle satellite cell activation(GO:0014719) recognition of apoptotic cell(GO:0043654)
0.1 1.0 GO:0009644 response to high light intensity(GO:0009644)
0.0 1.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 0.9 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.0 0.9 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.8 GO:0033572 transferrin transport(GO:0033572)
0.0 0.8 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.8 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.7 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.6 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.5 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.4 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0005916 fascia adherens(GO:0005916)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.1 0.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.4 GO:0030507 spectrin binding(GO:0030507)
0.0 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.0 GO:0001849 complement component C1q binding(GO:0001849)
0.3 0.9 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.3 0.8 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.8 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 0.6 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 0.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.1 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.8 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.1 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 0.7 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.7 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.0 0.2 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling