Motif ID: Ets2
Z-value: 1.488
Transcription factors associated with Ets2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Ets2 | ENSMUSG00000022895.8 | Ets2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Ets2 | mm10_v2_chr16_+_95702044_95702094 | 0.82 | 3.5e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 13.5 | GO:2000580 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 1.1 | 3.3 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.9 | 2.6 | GO:0043323 | positive regulation of natural killer cell degranulation(GO:0043323) |
| 0.8 | 7.1 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.8 | 0.8 | GO:0018307 | enzyme active site formation(GO:0018307) |
| 0.6 | 5.0 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.5 | 2.7 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
| 0.5 | 8.1 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.5 | 2.5 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.5 | 0.5 | GO:1905072 | cardiac jelly development(GO:1905072) |
| 0.5 | 0.5 | GO:0034241 | positive regulation of macrophage fusion(GO:0034241) |
| 0.4 | 2.2 | GO:0015871 | astrocyte activation involved in immune response(GO:0002265) choline transport(GO:0015871) |
| 0.4 | 1.7 | GO:0098904 | regulation of AV node cell action potential(GO:0098904) |
| 0.4 | 1.6 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.4 | 4.4 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 0.4 | 2.7 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.4 | 1.6 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.4 | 1.8 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.4 | 1.1 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
| 0.3 | 1.0 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
| 0.3 | 2.0 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.3 | 3.2 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
| 0.3 | 2.5 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
| 0.3 | 0.9 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 0.3 | 0.9 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.3 | 1.1 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
| 0.3 | 1.7 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.3 | 1.1 | GO:0071105 | response to interleukin-11(GO:0071105) |
| 0.3 | 1.1 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
| 0.3 | 4.3 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 0.3 | 0.8 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 0.3 | 0.8 | GO:1902277 | negative regulation of pancreatic amylase secretion(GO:1902277) |
| 0.3 | 0.5 | GO:0035990 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
| 0.2 | 0.7 | GO:0002765 | tolerance induction to self antigen(GO:0002513) immune response-inhibiting signal transduction(GO:0002765) positive regulation of dendritic cell apoptotic process(GO:2000670) |
| 0.2 | 1.9 | GO:0035635 | entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535) |
| 0.2 | 1.4 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.2 | 1.2 | GO:0010637 | diet induced thermogenesis(GO:0002024) negative regulation of mitochondrial fusion(GO:0010637) |
| 0.2 | 1.1 | GO:0042117 | monocyte activation(GO:0042117) |
| 0.2 | 4.3 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 0.2 | 0.8 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.2 | 0.8 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.2 | 1.7 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.2 | 0.6 | GO:0019046 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) release from viral latency(GO:0019046) |
| 0.2 | 1.3 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.2 | 1.5 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.2 | 1.1 | GO:0017185 | peptidyl-lysine hydroxylation(GO:0017185) |
| 0.2 | 0.9 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.2 | 0.9 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.2 | 0.7 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
| 0.2 | 0.5 | GO:0039533 | regulation of MDA-5 signaling pathway(GO:0039533) |
| 0.2 | 0.7 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 0.2 | 1.3 | GO:0036506 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.2 | 1.4 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.2 | 1.3 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.2 | 1.1 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.2 | 0.6 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.2 | 1.1 | GO:0023035 | CD40 signaling pathway(GO:0023035) protein linear polyubiquitination(GO:0097039) |
| 0.1 | 2.2 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.1 | 0.9 | GO:0070447 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) |
| 0.1 | 2.8 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.1 | 2.8 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 0.9 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.1 | 0.8 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.1 | 1.6 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 0.9 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.1 | 0.6 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.1 | 1.4 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 0.8 | GO:1990009 | retinal cell apoptotic process(GO:1990009) |
| 0.1 | 0.6 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 0.1 | 0.3 | GO:0048162 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
| 0.1 | 1.3 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.1 | 0.9 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.1 | 0.5 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.1 | 3.0 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.1 | 0.4 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.1 | 1.3 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.1 | 1.0 | GO:1903351 | response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) |
| 0.1 | 1.2 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.1 | 1.7 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.1 | 0.6 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.1 | 1.5 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.1 | 2.9 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.1 | 2.2 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 1.7 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.1 | 3.3 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.1 | 0.6 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 0.2 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.1 | 18.7 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
| 0.1 | 0.3 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.1 | 0.4 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.1 | 4.2 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.1 | 1.1 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 0.8 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.1 | 1.8 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.1 | 0.4 | GO:0001955 | blood vessel maturation(GO:0001955) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.1 | 2.6 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.1 | 0.6 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.1 | 0.3 | GO:0010635 | regulation of mitochondrial fusion(GO:0010635) |
| 0.1 | 0.3 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.1 | 1.5 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.1 | 0.8 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 2.3 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.1 | 0.3 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.1 | 0.9 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 2.3 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
| 0.1 | 2.4 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.1 | 0.4 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.1 | 1.2 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.1 | 0.3 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
| 0.1 | 0.2 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 0.0 | 0.9 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.0 | 0.3 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.0 | 0.2 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.0 | 1.9 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 1.1 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.0 | 2.1 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 0.3 | GO:0002687 | positive regulation of leukocyte migration(GO:0002687) |
| 0.0 | 0.4 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.0 | 0.8 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.0 | 0.2 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.0 | 0.1 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 0.0 | 0.6 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
| 0.0 | 1.6 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 2.2 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
| 0.0 | 0.2 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.0 | 0.8 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
| 0.0 | 1.2 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.1 | GO:1905076 | interleukin-17 secretion(GO:0072615) regulation of interleukin-17 secretion(GO:1905076) |
| 0.0 | 0.1 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.0 | 0.6 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 0.0 | 1.9 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity(GO:0032088) |
| 0.0 | 0.5 | GO:0009072 | aromatic amino acid family metabolic process(GO:0009072) |
| 0.0 | 3.4 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.0 | 0.5 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.0 | 0.3 | GO:0030049 | muscle filament sliding(GO:0030049) |
| 0.0 | 0.2 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
| 0.0 | 0.1 | GO:1990564 | protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.0 | 0.5 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
| 0.0 | 0.5 | GO:0005980 | polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
| 0.0 | 0.2 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.0 | 0.2 | GO:0071361 | cellular response to ethanol(GO:0071361) |
| 0.0 | 0.1 | GO:0048793 | pronephros development(GO:0048793) |
| 0.0 | 0.2 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 2.1 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.5 | GO:0045761 | regulation of adenylate cyclase activity(GO:0045761) |
| 0.0 | 0.3 | GO:0021819 | layer formation in cerebral cortex(GO:0021819) radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.0 | 0.1 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.0 | 0.1 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.0 | 0.2 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
| 0.0 | 0.6 | GO:0045026 | plasma membrane fusion(GO:0045026) |
| 0.0 | 0.2 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
| 0.0 | 0.7 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.0 | 0.2 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.4 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.0 | 0.3 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
| 0.0 | 0.1 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.0 | 2.3 | GO:0030010 | establishment of cell polarity(GO:0030010) |
| 0.0 | 0.9 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.0 | 0.2 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.0 | 0.3 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 0.1 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.0 | 0.1 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.0 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
| 0.0 | 0.3 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 0.6 | GO:0007032 | endosome organization(GO:0007032) |
| 0.0 | 0.1 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 0.0 | 0.0 | GO:0060125 | negative regulation of growth hormone secretion(GO:0060125) |
| 0.0 | 0.1 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.0 | 0.4 | GO:0010824 | regulation of centrosome duplication(GO:0010824) |
| 0.0 | 0.7 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.0 | 1.1 | GO:0007188 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188) |
| 0.0 | 0.2 | GO:0032988 | ribonucleoprotein complex disassembly(GO:0032988) |
| 0.0 | 0.1 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 0.0 | 1.8 | GO:0051262 | protein tetramerization(GO:0051262) |
| 0.0 | 0.3 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 1.5 | GO:0098656 | anion transmembrane transport(GO:0098656) |
| 0.0 | 1.0 | GO:0031123 | RNA 3'-end processing(GO:0031123) |
| 0.0 | 0.8 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.1 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.0 | 0.4 | GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway(GO:2001238) |
| 0.0 | 0.2 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 13.5 | GO:1990257 | piccolo-bassoon transport vesicle(GO:1990257) |
| 0.8 | 3.3 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.7 | 2.2 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.5 | 4.3 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.5 | 4.4 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.4 | 2.7 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.4 | 2.5 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.4 | 1.8 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.4 | 1.4 | GO:0019034 | viral replication complex(GO:0019034) |
| 0.3 | 3.5 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.3 | 1.0 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.3 | 1.9 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.3 | 0.9 | GO:0000799 | nuclear condensin complex(GO:0000799) germinal vesicle(GO:0042585) |
| 0.3 | 1.1 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.3 | 0.8 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.3 | 2.2 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.3 | 2.9 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.3 | 0.8 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.3 | 7.1 | GO:0031430 | M band(GO:0031430) |
| 0.2 | 2.4 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.2 | 1.7 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.2 | 0.7 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
| 0.2 | 0.4 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.2 | 10.5 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.2 | 1.3 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.2 | 3.5 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.2 | 1.2 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.1 | 0.9 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 0.9 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.1 | 4.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 9.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 1.5 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.1 | 0.5 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
| 0.1 | 1.1 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.1 | 0.9 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.1 | 0.9 | GO:0097433 | dense body(GO:0097433) HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 0.7 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 0.3 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.1 | 1.3 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 1.0 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 1.6 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.1 | 2.6 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 1.4 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 1.4 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 9.4 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.1 | 0.7 | GO:0061700 | Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700) |
| 0.1 | 3.7 | GO:0030117 | membrane coat(GO:0030117) coated membrane(GO:0048475) |
| 0.1 | 2.1 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 0.6 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 2.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 0.5 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.1 | 0.2 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.1 | 1.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 1.2 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 2.1 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 1.6 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.3 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 1.2 | GO:0030904 | retromer complex(GO:0030904) |
| 0.0 | 0.2 | GO:0071008 | B cell receptor complex(GO:0019815) U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.0 | 1.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.2 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 1.7 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 0.8 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 0.8 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 4.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.2 | GO:0072487 | MSL complex(GO:0072487) |
| 0.0 | 0.7 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 1.5 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.4 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 0.5 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.3 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.0 | 1.2 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.0 | 0.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.3 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 0.1 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 5.3 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.3 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 0.6 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.4 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.3 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 0.2 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.0 | 5.0 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 0.1 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 13.5 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.7 | 3.6 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.6 | 3.3 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.4 | 1.1 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.3 | 1.7 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.3 | 1.7 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.3 | 0.9 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.3 | 1.4 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.3 | 2.2 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.3 | 1.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.3 | 0.8 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 0.3 | 1.6 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.3 | 1.6 | GO:0070728 | leucine binding(GO:0070728) |
| 0.2 | 0.7 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 0.2 | 0.9 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.2 | 1.1 | GO:0019961 | interferon binding(GO:0019961) |
| 0.2 | 2.4 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.2 | 1.5 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.2 | 0.6 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.2 | 3.3 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.2 | 0.8 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.2 | 4.4 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.2 | 0.5 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 0.2 | 1.5 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.2 | 0.8 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.2 | 0.8 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 0.1 | 10.3 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.1 | 2.3 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.1 | 0.8 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.1 | 7.1 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 0.9 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.1 | 3.0 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.1 | 0.4 | GO:0004534 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534) |
| 0.1 | 2.8 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.9 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.1 | 0.6 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.1 | 12.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.1 | 1.5 | GO:0035004 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004) phosphatidylinositol kinase activity(GO:0052742) |
| 0.1 | 0.5 | GO:0005534 | galactose binding(GO:0005534) |
| 0.1 | 11.3 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 2.5 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.1 | 1.2 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 3.9 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 1.3 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 0.5 | GO:0089720 | caspase binding(GO:0089720) |
| 0.1 | 3.3 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 0.5 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.1 | 0.2 | GO:0000992 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
| 0.1 | 3.0 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.1 | 1.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.2 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.1 | 1.3 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 0.3 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.1 | 0.9 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 1.4 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 0.2 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.1 | 0.2 | GO:0016501 | prostacyclin receptor activity(GO:0016501) |
| 0.1 | 1.7 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.1 | 0.8 | GO:0045503 | dynein light chain binding(GO:0045503) |
| 0.1 | 1.4 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 1.1 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.1 | 1.0 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 0.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 0.6 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
| 0.0 | 3.1 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.1 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.0 | 0.4 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 0.8 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.6 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 1.1 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 2.0 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.5 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.3 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 1.1 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 4.0 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 0.3 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 0.1 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.0 | 0.1 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.0 | 0.5 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 1.1 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
| 0.0 | 1.1 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 0.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 4.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.8 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.3 | GO:0031543 | peptidyl-proline dioxygenase activity(GO:0031543) |
| 0.0 | 0.2 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.5 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 4.0 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.8 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 0.2 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.0 | 0.2 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 1.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.1 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 0.0 | 0.4 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 0.1 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.0 | 0.1 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 1.5 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.0 | 0.0 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
| 0.0 | 0.8 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.7 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.2 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.0 | 0.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 6.4 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 0.6 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.8 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 1.3 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 2.2 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 0.1 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 0.3 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.0 | 0.1 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.2 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 7.8 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
| 0.1 | 4.7 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 2.7 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.1 | 4.4 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
| 0.1 | 2.8 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 3.3 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.1 | 0.3 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
| 0.1 | 4.0 | PID_INSULIN_PATHWAY | Insulin Pathway |
| 0.1 | 1.6 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.1 | 4.3 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 1.1 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.1 | 0.3 | PID_MYC_PATHWAY | C-MYC pathway |
| 0.1 | 0.7 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
| 0.0 | 1.0 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.0 | 1.6 | PID_BCR_5PATHWAY | BCR signaling pathway |
| 0.0 | 1.5 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 1.3 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 1.2 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.0 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.5 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.6 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.0 | 0.8 | ST_GAQ_PATHWAY | G alpha q Pathway |
| 0.0 | 1.1 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.7 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.3 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
| 0.0 | 0.7 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 0.9 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.6 | PID_MTOR_4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.1 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.4 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.3 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 6.2 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.4 | 8.7 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.2 | 0.2 | REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.2 | 3.2 | REACTOME_SIGNALING_BY_NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.2 | 4.4 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
| 0.2 | 2.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.2 | 15.3 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.2 | 1.4 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.1 | 1.8 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 2.6 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 0.8 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.1 | 0.9 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.1 | 1.3 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 5.9 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 0.8 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 1.9 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.1 | 1.2 | REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.1 | 1.2 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 2.5 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 1.9 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.1 | 2.4 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.1 | 0.8 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 1.7 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 4.3 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.2 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.0 | 0.8 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 2.8 | REACTOME_REGULATION_OF_INSULIN_SECRETION | Genes involved in Regulation of Insulin Secretion |
| 0.0 | 1.1 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.8 | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 1.9 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.0 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 2.4 | REACTOME_GENERIC_TRANSCRIPTION_PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.0 | 0.3 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.9 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 1.2 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.3 | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.4 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.4 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.1 | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.0 | 0.1 | REACTOME_ER_PHAGOSOME_PATHWAY | Genes involved in ER-Phagosome pathway |
