Motif ID: Foxd1
Z-value: 1.866
Transcription factors associated with Foxd1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxd1 | ENSMUSG00000078302.3 | Foxd1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxd1 | mm10_v2_chr13_+_98354234_98354250 | -0.56 | 1.7e-02 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 120 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 29.7 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 2.2 | 15.5 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.6 | 11.1 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 2.2 | 10.9 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 2.2 | 8.6 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.8 | 7.5 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 0.1 | 7.3 | GO:0030010 | establishment of cell polarity(GO:0030010) |
| 1.7 | 6.7 | GO:0002069 | columnar/cuboidal epithelial cell maturation(GO:0002069) |
| 2.0 | 5.9 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.3 | 5.9 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
| 1.8 | 5.4 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 0.3 | 5.4 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.5 | 4.9 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.9 | 4.7 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.8 | 4.7 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.6 | 4.5 | GO:0035826 | rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476) |
| 0.2 | 4.5 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.4 | 4.4 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.0 | 4.4 | GO:0046488 | phosphatidylinositol metabolic process(GO:0046488) |
| 1.4 | 4.2 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 58 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 13.1 | GO:0005667 | transcription factor complex(GO:0005667) |
| 2.8 | 11.1 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.0 | 7.8 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 7.7 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 7.4 | GO:0031252 | cell leading edge(GO:0031252) |
| 0.2 | 6.5 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.2 | 5.9 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 5.6 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.1 | 5.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.2 | 4.4 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 4.3 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 4.2 | GO:0030673 | axolemma(GO:0030673) |
| 1.0 | 4.0 | GO:1902737 | viral replication complex(GO:0019034) dendritic filopodium(GO:1902737) |
| 1.0 | 4.0 | GO:0031673 | H zone(GO:0031673) |
| 0.6 | 3.9 | GO:0035976 | AP1 complex(GO:0035976) |
| 1.2 | 3.7 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.3 | 3.4 | GO:0030057 | desmosome(GO:0030057) |
| 0.3 | 3.2 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.0 | 3.1 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.2 | 3.0 | GO:0071564 | npBAF complex(GO:0071564) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 86 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.2 | 29.7 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 5.2 | 15.5 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.6 | 13.3 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 12.6 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.7 | 8.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 7.9 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.4 | 6.0 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 6.0 | GO:0070888 | E-box binding(GO:0070888) |
| 0.5 | 5.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 5.3 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.8 | 4.9 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.1 | 4.9 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.6 | 4.5 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.6 | 4.4 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.4 | 4.4 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.5 | 4.2 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.6 | 4.0 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 1.0 | 3.9 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.6 | 3.9 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 3.9 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 32 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 37.7 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 15.4 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.3 | 10.1 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 8.6 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.3 | 7.9 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.4 | 7.4 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.1 | 6.0 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
| 0.3 | 5.9 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.1 | 5.1 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.1 | 4.9 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 4.4 | PID_FOXO_PATHWAY | FoxO family signaling |
| 0.2 | 3.9 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 3.9 | PID_IL3_PATHWAY | IL3-mediated signaling events |
| 0.1 | 3.9 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 3.2 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 2.5 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
| 0.1 | 2.1 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 2.0 | PID_P53_REGULATION_PATHWAY | p53 pathway |
| 0.1 | 1.9 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.1 | 1.8 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 35 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 11.1 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.2 | 7.9 | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | Genes involved in Post NMDA receptor activation events |
| 0.3 | 5.8 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 5.8 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 4.4 | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.1 | 4.2 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.2 | 3.9 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.1 | 3.9 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.3 | 3.7 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.3 | 3.5 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.2 | 3.5 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.2 | 3.4 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 3.3 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 2.8 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 2.3 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.3 | 2.1 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.1 | 2.1 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 1.6 | REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.0 | 1.6 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.3 | 1.5 | REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
