Motif ID: Foxf1

Z-value: 0.668


Transcription factors associated with Foxf1:

Gene SymbolEntrez IDGene Name
Foxf1 ENSMUSG00000042812.4 Foxf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxf1mm10_v2_chr8_+_121084352_1210844740.233.6e-01Click!


Activity profile for motif Foxf1.

activity profile for motif Foxf1


Sorted Z-values histogram for motif Foxf1

Sorted Z-values for motif Foxf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_68117713 1.524 ENSMUST00000112346.2
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr1_+_66386968 1.262 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr16_+_91269759 1.238 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr6_-_59024470 1.141 ENSMUST00000089860.5
 Fam13a
family with sequence similarity 13, member A
chr18_+_67133713 1.107 ENSMUST00000076605.7
 Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr7_-_103813913 1.101 ENSMUST00000098192.3
 Hbb-bt
hemoglobin, beta adult t chain
chr2_+_65620829 1.074 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr19_+_38264761 1.069 ENSMUST00000087252.5
 Lgi1
leucine-rich repeat LGI family, member 1
chr13_-_110280103 1.068 ENSMUST00000167824.1
 Rab3c
RAB3C, member RAS oncogene family
chr14_-_30353468 1.066 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chrX_-_51681856 1.032 ENSMUST00000114871.1
 Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr9_+_53850243 1.004 ENSMUST00000048485.5
 Sln
sarcolipin
chr15_+_92597104 0.997 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr7_-_4844665 0.924 ENSMUST00000066041.5
ENSMUST00000172377.1
 Shisa7

shisa homolog 7 (Xenopus laevis)

chr6_-_148444336 0.916 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr17_+_70522083 0.903 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr18_+_36939178 0.854 ENSMUST00000115662.2
 Pcdha2
protocadherin alpha 2
chr2_+_68104671 0.799 ENSMUST00000042456.3
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr5_-_103211251 0.779 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
 Mapk10



mitogen-activated protein kinase 10



chr14_-_88471396 0.768 ENSMUST00000061628.5
 Pcdh20
protocadherin 20

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.6 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 1.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 1.1 GO:0009405 pathogenesis(GO:0009405)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 1.0 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.2 1.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 1.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.8 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.7 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.7 GO:0015809 arginine transport(GO:0015809)
0.2 0.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.6 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.1 1.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 1.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.3 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 1.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 1.1 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.1 1.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.3 1.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 0.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.7 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.2 0.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)

Gene overrepresentation in C2:CP category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID_LKB1_PATHWAY LKB1 signaling events
0.1 1.1 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.9 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.8 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.8 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.3 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.1 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.2 1.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.2 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism