Motif ID: Foxj3_Tbl1xr1

Z-value: 0.876

Transcription factors associated with Foxj3_Tbl1xr1:

Gene SymbolEntrez IDGene Name
Foxj3 ENSMUSG00000032998.10 Foxj3
Tbl1xr1 ENSMUSG00000027630.8 Tbl1xr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj3mm10_v2_chr4_+_119539652_119539698-0.719.5e-04Click!
Tbl1xr1mm10_v2_chr3_+_22076644_22076681-0.465.6e-02Click!


Activity profile for motif Foxj3_Tbl1xr1.

activity profile for motif Foxj3_Tbl1xr1


Sorted Z-values histogram for motif Foxj3_Tbl1xr1

Sorted Z-values for motif Foxj3_Tbl1xr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxj3_Tbl1xr1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_100514800 2.605 ENSMUST00000054923.7
 Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr16_-_26989974 1.860 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr7_-_103853199 1.739 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr14_-_98169542 1.699 ENSMUST00000069334.7
ENSMUST00000071533.6
 Dach1

dachshund 1 (Drosophila)

chr8_+_116504973 1.559 ENSMUST00000078170.5
 Dynlrb2
dynein light chain roadblock-type 2
chr10_-_85957775 1.379 ENSMUST00000001834.3
 Rtcb
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr10_-_120476469 1.323 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr11_+_44617310 1.284 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr6_-_23248264 1.275 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chrX_-_134161928 1.252 ENSMUST00000033611.4
 Xkrx
X Kell blood group precursor related X linked
chr4_-_92191749 1.240 ENSMUST00000123179.1
 Gm12666
predicted gene 12666
chr10_-_92165159 1.239 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
 Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr9_+_115909455 1.230 ENSMUST00000119291.1
ENSMUST00000069651.6
 Gadl1

glutamate decarboxylase-like 1

chrX_-_106485214 1.224 ENSMUST00000039447.7
 Fndc3c1
fibronectin type III domain containing 3C1
chr7_+_31059342 1.188 ENSMUST00000039775.7
 Lgi4
leucine-rich repeat LGI family, member 4
chr5_-_106458440 1.155 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr10_-_128549102 1.136 ENSMUST00000176906.1
 Rpl41
ribosomal protein L41
chr10_-_92164666 1.095 ENSMUST00000183123.1
ENSMUST00000182033.1
 Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr19_+_55741810 1.089 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr9_-_37613715 1.067 ENSMUST00000002013.9
 Spa17
sperm autoantigenic protein 17

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 898 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 4.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 4.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 3.9 GO:0032543 mitochondrial translation(GO:0032543)
0.6 3.1 GO:0015671 oxygen transport(GO:0015671)
0.3 3.0 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 2.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 2.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 2.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 2.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 2.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 2.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 2.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 2.1 GO:0035082 axoneme assembly(GO:0035082)
0.1 2.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.9 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.6 1.8 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 1.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 1.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 1.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 310 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 10.2 GO:0005615 extracellular space(GO:0005615)
0.2 6.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 6.1 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 6.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 5.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.5 4.1 GO:0005833 hemoglobin complex(GO:0005833)
0.1 3.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 3.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 3.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.1 GO:0036126 sperm flagellum(GO:0036126)
0.1 2.9 GO:0000786 nucleosome(GO:0000786)
0.3 2.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 2.7 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 2.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 2.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 2.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.1 2.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 2.0 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 489 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 19.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 4.4 GO:0035326 enhancer binding(GO:0035326)
0.0 4.0 GO:0051082 unfolded protein binding(GO:0051082)
0.1 3.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 3.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 2.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.6 2.5 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 2.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 2.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 2.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.2 GO:0070888 E-box binding(GO:0070888)
0.1 2.1 GO:0001848 complement binding(GO:0001848)
0.2 2.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 1.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 1.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 1.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 4.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 2.8 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 2.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.4 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.2 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 2.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.9 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 1.8 NABA_MATRISOME_ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 1.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.7 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.1 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 1.0 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 145 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 17.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.2 8.3 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 8.2 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 7.6 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 5.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 2.8 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 2.3 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 2.3 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 2.2 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 2.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 2.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 2.0 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 2.0 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 1.7 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development