Motif ID: Foxm1

Z-value: 0.693


Transcription factors associated with Foxm1:

Gene SymbolEntrez IDGene Name
Foxm1 ENSMUSG00000001517.8 Foxm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxm1mm10_v2_chr6_+_128362919_1283630580.312.2e-01Click!


Activity profile for motif Foxm1.

activity profile for motif Foxm1


Sorted Z-values histogram for motif Foxm1

Sorted Z-values for motif Foxm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 149 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_23890805 1.641 ENSMUST00000004480.3
 Sst
somatostatin
chr1_-_138842429 1.450 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr10_+_127421208 1.347 ENSMUST00000168780.1
 R3hdm2
R3H domain containing 2
chr13_+_23934434 1.206 ENSMUST00000072391.1
 Hist1h2aa
histone cluster 1, H2aa
chr9_+_22454290 1.032 ENSMUST00000168332.1
 Gm17545
predicted gene, 17545
chr10_-_88605017 1.025 ENSMUST00000119185.1
ENSMUST00000121629.1
 Mybpc1

myosin binding protein C, slow-type

chr12_-_56536895 1.008 ENSMUST00000001536.8
 Nkx2-1
NK2 homeobox 1
chrX_+_164373363 0.826 ENSMUST00000033751.7
 Figf
c-fos induced growth factor
chr12_-_51971289 0.758 ENSMUST00000040583.5
 Heatr5a
HEAT repeat containing 5A
chr10_+_112928501 0.750 ENSMUST00000180464.1
 Gm26596
predicted gene, 26596
chr1_-_79440039 0.703 ENSMUST00000049972.4
 Scg2
secretogranin II
chr5_-_87490869 0.679 ENSMUST00000147854.1
 Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr8_+_34807287 0.608 ENSMUST00000033930.4
 Dusp4
dual specificity phosphatase 4
chr18_-_66022580 0.580 ENSMUST00000143990.1
 Lman1
lectin, mannose-binding, 1
chr3_+_106113229 0.577 ENSMUST00000079132.5
ENSMUST00000139086.1
 Chia

chitinase, acidic

chr4_-_36136463 0.575 ENSMUST00000098151.2
 Lingo2
leucine rich repeat and Ig domain containing 2
chr19_-_58455903 0.575 ENSMUST00000131877.1
 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr7_+_83755904 0.544 ENSMUST00000051522.8
ENSMUST00000042280.7
 Gm7964

predicted gene 7964

chrX_-_141725181 0.538 ENSMUST00000067841.7
 Irs4
insulin receptor substrate 4
chr18_-_62756275 0.537 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)
0.3 1.0 GO:0021759 globus pallidus development(GO:0021759)
0.2 1.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.2 0.5 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.5 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.5 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.4 GO:0060591 chondroblast differentiation(GO:0060591)
0.1 0.4 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.1 0.4 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 0.4 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.0 0.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.4 GO:1903146 regulation of mitophagy(GO:1903146)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 0.5 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 1.2 GO:0005178 integrin binding(GO:0005178)
0.2 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.2 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.1 0.5 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)

Gene overrepresentation in C2:CP category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 0.8 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.7 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.6 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.1 0.5 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.9 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.8 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins