Motif ID: Foxn1

Z-value: 0.457


Transcription factors associated with Foxn1:

Gene SymbolEntrez IDGene Name
Foxn1 ENSMUSG00000002057.4 Foxn1



Activity profile for motif Foxn1.

activity profile for motif Foxn1


Sorted Z-values histogram for motif Foxn1

Sorted Z-values for motif Foxn1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxn1

PNG image of the network

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Top targets:


Showing 1 to 20 of 109 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_119578981 0.878 ENSMUST00000117911.1
ENSMUST00000120420.1
 Scn5a

sodium channel, voltage-gated, type V, alpha

chr7_+_123982799 0.807 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr19_+_43612299 0.797 ENSMUST00000057178.9
 Nkx2-3
NK2 homeobox 3
chr10_+_19934472 0.467 ENSMUST00000095806.3
ENSMUST00000120259.1
 Map3k5

mitogen-activated protein kinase kinase kinase 5

chr11_-_69758223 0.409 ENSMUST00000071213.3
 Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr13_-_64274879 0.398 ENSMUST00000109770.1
 Cdc14b
CDC14 cell division cycle 14B
chr9_-_45984816 0.382 ENSMUST00000172450.1
 Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr17_+_26561479 0.354 ENSMUST00000167662.1
 Ergic1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr8_-_94012120 0.343 ENSMUST00000143265.1
 Amfr
autocrine motility factor receptor
chr11_-_69758630 0.338 ENSMUST00000058470.9
 Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr17_+_47688992 0.305 ENSMUST00000156118.1
 Frs3
fibroblast growth factor receptor substrate 3
chr9_+_21592722 0.304 ENSMUST00000062125.10
 1810026J23Rik
RIKEN cDNA 1810026J23 gene
chr1_-_155099630 0.300 ENSMUST00000055322.4
 Ier5
immediate early response 5
chr19_+_46152505 0.291 ENSMUST00000026254.7
 Gbf1
golgi-specific brefeldin A-resistance factor 1
chr10_+_88379127 0.283 ENSMUST00000127615.1
 Gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr2_-_163645125 0.281 ENSMUST00000017851.3
 Serinc3
serine incorporator 3
chrX_+_151803642 0.278 ENSMUST00000156616.2
 Huwe1
HECT, UBA and WWE domain containing 1
chr8_-_72571033 0.277 ENSMUST00000058733.8
ENSMUST00000167290.1
 Smim7

small integral membrane protein 7

chr11_+_67455339 0.262 ENSMUST00000108681.1
 Gas7
growth arrest specific 7
chr7_+_100372224 0.259 ENSMUST00000051777.8
ENSMUST00000098259.4
 C2cd3

C2 calcium-dependent domain containing 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 0.9 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.1 0.8 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.7 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.5 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.3 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.3 GO:0009597 detection of virus(GO:0009597)
0.1 0.3 GO:0061511 centriole elongation(GO:0061511)
0.0 0.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.2 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.0 0.2 GO:0010796 regulation of multivesicular body size(GO:0010796) multivesicular body assembly(GO:0036258)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:1904668 mitotic spindle midzone assembly(GO:0051256) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.1 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.7 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID_ARF_3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins