Motif ID: Foxq1

Z-value: 1.054


Transcription factors associated with Foxq1:

Gene SymbolEntrez IDGene Name
Foxq1 ENSMUSG00000038415.8 Foxq1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxq1mm10_v2_chr13_+_31558157_315581760.165.2e-01Click!


Activity profile for motif Foxq1.

activity profile for motif Foxq1


Sorted Z-values histogram for motif Foxq1

Sorted Z-values for motif Foxq1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxq1

PNG image of the network

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Top targets:


Showing 1 to 20 of 124 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_30353468 5.490 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr18_-_89769479 3.426 ENSMUST00000097495.3
Dok6
docking protein 6
chr2_+_76406529 3.204 ENSMUST00000111929.1
ENSMUST00000077972.4
ENSMUST00000111930.2
Osbpl6


oxysterol binding protein-like 6


chr16_+_43363855 3.023 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr7_+_110772604 2.929 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr1_-_170110491 2.892 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr5_-_122002340 2.701 ENSMUST00000134326.1
Cux2
cut-like homeobox 2
chr10_+_60106452 2.513 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr16_+_43364145 2.490 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr5_+_122643878 2.484 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr4_-_129121889 2.472 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr7_+_45783883 2.301 ENSMUST00000072580.5
Lmtk3
lemur tyrosine kinase 3
chr18_+_37496997 2.278 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr2_-_77519565 2.259 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chrX_-_103483205 2.193 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr17_+_35076902 2.150 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr19_-_28963863 2.106 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr18_+_51117754 2.017 ENSMUST00000116639.2
Prr16
proline rich 16
chr7_+_19176416 2.012 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr15_-_58214882 1.979 ENSMUST00000022986.6
Fbxo32
F-box protein 32

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.0 GO:0007416 synapse assembly(GO:0007416)
1.4 5.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 5.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 4.0 GO:0006869 lipid transport(GO:0006869)
0.1 3.7 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.2 3.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.4 2.9 GO:0032264 IMP salvage(GO:0032264)
0.4 2.9 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 2.9 GO:0007614 short-term memory(GO:0007614)
0.8 2.5 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170)
0.8 2.5 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.7 2.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 2.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
1.0 2.0 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.3 2.0 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 2.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 2.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.6 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.5 GO:0008210 estrogen metabolic process(GO:0008210)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 5.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 3.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 3.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 3.2 GO:0016324 apical plasma membrane(GO:0016324)
0.1 2.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 2.5 GO:0044327 dendritic spine head(GO:0044327)
0.2 2.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.2 2.2 GO:0000805 X chromosome(GO:0000805)
0.0 2.2 GO:0001650 fibrillar center(GO:0001650)
0.0 2.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.0 GO:0072686 mitotic spindle(GO:0072686)
0.1 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 1.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.7 5.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
1.2 3.7 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 3.0 GO:0008017 microtubule binding(GO:0008017)
0.4 2.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 2.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 2.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 2.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.4 1.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.4 1.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.2 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)

Gene overrepresentation in C2:CP category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 PID_FOXO_PATHWAY FoxO family signaling
0.0 1.5 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 1.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.1 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.4 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.9 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.4 2.5 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.2 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.1 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 1.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.0 0.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity