Motif ID: Fubp1

Z-value: 0.802


Transcription factors associated with Fubp1:

Gene SymbolEntrez IDGene Name
Fubp1 ENSMUSG00000028034.9 Fubp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fubp1mm10_v2_chr3_+_152210458_1522105340.312.0e-01Click!


Activity profile for motif Fubp1.

activity profile for motif Fubp1


Sorted Z-values histogram for motif Fubp1

Sorted Z-values for motif Fubp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Fubp1

PNG image of the network

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Top targets:


Showing 1 to 20 of 118 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_106485214 5.407 ENSMUST00000039447.7
 Fndc3c1
fibronectin type III domain containing 3C1
chr14_-_48667508 4.134 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
 Otx2



orthodenticle homolog 2 (Drosophila)



chr11_+_44617310 3.929 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr14_-_98169542 3.164 ENSMUST00000069334.7
ENSMUST00000071533.6
 Dach1

dachshund 1 (Drosophila)

chr1_+_156366037 2.398 ENSMUST00000102782.3
 Gm2000
predicted gene 2000
chr6_+_17307632 2.325 ENSMUST00000115453.1
 Cav1
caveolin 1, caveolae protein
chr3_-_157925056 2.267 ENSMUST00000118539.1
 Cth
cystathionase (cystathionine gamma-lyase)
chr7_-_137314394 2.190 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr2_+_103970115 1.957 ENSMUST00000111143.1
ENSMUST00000138815.1
 Lmo2

LIM domain only 2

chr18_+_86711520 1.950 ENSMUST00000122464.1
 Cbln2
cerebellin 2 precursor protein
chr2_+_103970221 1.923 ENSMUST00000111140.2
ENSMUST00000111139.2
 Lmo2

LIM domain only 2

chr12_-_80112998 1.923 ENSMUST00000165114.1
ENSMUST00000021552.1
 Zfp36l1

zinc finger protein 36, C3H type-like 1

chr18_+_86711059 1.756 ENSMUST00000068423.3
 Cbln2
cerebellin 2 precursor protein
chr2_+_103969528 1.607 ENSMUST00000123437.1
ENSMUST00000163256.1
 Lmo2

LIM domain only 2

chr18_+_35536539 1.574 ENSMUST00000081864.3
 Gm5239
predicted pseudogene 5239
chr13_-_21780616 1.573 ENSMUST00000080511.2
 Hist1h1b
histone cluster 1, H1b
chr13_-_78199757 1.556 ENSMUST00000091458.6
 Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr2_-_28916412 1.525 ENSMUST00000050776.2
ENSMUST00000113849.1
 Barhl1

BarH-like 1 (Drosophila)

chr10_+_53596936 1.427 ENSMUST00000020004.6
 Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr2_-_69206146 1.375 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
 Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
1.0 4.1 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 3.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
1.1 3.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 2.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 2.5 GO:0007052 mitotic spindle organization(GO:0007052)
0.8 2.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.5 2.3 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.6 1.9 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.0 1.5 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 1.5 GO:0030901 midbrain development(GO:0030901)
0.3 1.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 1.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 1.2 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.4 1.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.3 1.0 GO:0072092 ureteric bud invasion(GO:0072092)
0.3 1.0 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 1.0 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.1 1.0 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 1.0 GO:0051225 spindle assembly(GO:0051225)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.1 GO:0030426 growth cone(GO:0030426)
0.4 2.5 GO:0031262 Ndc80 complex(GO:0031262)
0.2 2.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.6 GO:0000786 nucleosome(GO:0000786)
0.2 1.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.0 1.0 GO:0010369 chromocenter(GO:0010369)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.9 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.1 0.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.8 GO:0031105 septin complex(GO:0031105)
0.1 0.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 4.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 4.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.3 3.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.4 3.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 2.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 2.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 2.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 1.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3 1.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 1.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.3 1.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in C2:CP category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.1 PID_ALK1_PATHWAY ALK1 signaling events
0.1 2.3 PID_ATM_PATHWAY ATM pathway
0.0 2.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.6 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 1.0 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.5 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.3 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.1 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 1.9 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.9 REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.6 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.2 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.8 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.5 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation