Motif ID: Gata5
Z-value: 1.104
Transcription factors associated with Gata5:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Gata5 | ENSMUSG00000015627.5 | Gata5 |
Top targets:
Showing 1 to 20 of 128 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 54 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.7 | 18.4 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.1 | 2.9 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
| 0.7 | 2.0 | GO:0046462 | monoacylglycerol metabolic process(GO:0046462) |
| 0.0 | 2.0 | GO:0030177 | positive regulation of Wnt signaling pathway(GO:0030177) |
| 0.3 | 1.5 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
| 0.2 | 1.2 | GO:0060849 | regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
| 0.0 | 1.2 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.0 | 1.2 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.2 | 1.1 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.1 | 1.1 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.0 | 1.1 | GO:0048821 | erythrocyte development(GO:0048821) |
| 0.0 | 1.1 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
| 0.1 | 1.0 | GO:0006517 | protein deglycosylation(GO:0006517) |
| 0.1 | 0.8 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.2 | 0.7 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.1 | 0.7 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
| 0.0 | 0.7 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
| 0.2 | 0.6 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
| 0.1 | 0.6 | GO:0035878 | nail development(GO:0035878) |
| 0.1 | 0.6 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 22 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 19.2 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.0 | 2.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 1.4 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.4 | 1.1 | GO:0005584 | collagen type I trimer(GO:0005584) |
| 0.0 | 1.0 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.1 | 0.8 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 0.7 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.1 | 0.6 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.1 | 0.5 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.5 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.0 | 0.5 | GO:0036038 | MKS complex(GO:0036038) |
| 0.1 | 0.4 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 0.4 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.1 | 0.3 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.1 | 0.3 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.1 | 0.3 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.0 | 0.3 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
| 0.0 | 0.3 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 0.2 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.0 | 0.2 | GO:0032797 | SMN complex(GO:0032797) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 35 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.7 | 18.4 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.7 | 2.0 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.1 | 1.8 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.0 | 1.4 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.1 | 1.2 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 1.2 | GO:0005112 | Notch binding(GO:0005112) |
| 0.4 | 1.1 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 0.2 | 1.1 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.1 | 1.1 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.2 | 1.0 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.0 | 1.0 | GO:0043621 | protein self-association(GO:0043621) |
| 0.2 | 0.8 | GO:0031720 | haptoglobin binding(GO:0031720) |
| 0.0 | 0.8 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.0 | 0.8 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 0.7 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.0 | 0.7 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.1 | 0.6 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.0 | 0.6 | GO:0022842 | leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
| 0.0 | 0.6 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.5 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
Gene overrepresentation in C2:CP category:
Showing 1 to 10 of 10 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.2 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 1.7 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.2 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 1.1 | PID_LYMPH_ANGIOGENESIS_PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.0 | 1.1 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 0.8 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.7 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.1 | 0.6 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.4 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.3 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 14 of 14 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.9 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 1.2 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 1.2 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 1.1 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 1.1 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 1.1 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.0 | 1.0 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.0 | 0.7 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.6 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.1 | 0.5 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 0.5 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 0.5 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 0.3 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.2 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
