Motif ID: Gata6

Z-value: 0.541


Transcription factors associated with Gata6:

Gene SymbolEntrez IDGene Name
Gata6 ENSMUSG00000005836.8 Gata6



Activity profile for motif Gata6.

activity profile for motif Gata6


Sorted Z-values histogram for motif Gata6

Sorted Z-values for motif Gata6



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata6

PNG image of the network

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Top targets:


Showing 1 to 20 of 67 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_86732409 1.317 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr10_-_62342674 1.067 ENSMUST00000143179.1
ENSMUST00000130422.1
 Hk1

hexokinase 1

chr6_+_58833689 1.042 ENSMUST00000041401.8
 Herc3
hect domain and RLD 3
chr9_-_29963112 1.014 ENSMUST00000075069.4
 Ntm
neurotrimin
chr12_+_95692212 0.972 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr11_+_67586675 0.944 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr2_+_65930117 0.900 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr4_+_13751297 0.861 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_58831748 0.809 ENSMUST00000126292.1
ENSMUST00000031823.5
 Herc3

hect domain and RLD 3

chr1_+_152954966 0.804 ENSMUST00000043313.8
 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr3_-_154330543 0.800 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr19_+_58670358 0.750 ENSMUST00000057270.7
 Pnlip
pancreatic lipase
chr9_+_66350465 0.742 ENSMUST00000042824.6
 Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr6_+_86078070 0.705 ENSMUST00000032069.5
 Add2
adducin 2 (beta)
chr1_-_162866502 0.628 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr5_+_76840597 0.601 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
 C530008M17Rik


RIKEN cDNA C530008M17 gene


chr2_-_7081207 0.598 ENSMUST00000114923.2
ENSMUST00000182706.1
 Celf2

CUGBP, Elav-like family member 2

chr2_-_7396192 0.589 ENSMUST00000137733.2
 Celf2
CUGBP, Elav-like family member 2
chr2_+_68104671 0.582 ENSMUST00000042456.3
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr15_+_18818895 0.467 ENSMUST00000166873.2
 Cdh10
cadherin 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.2 1.1 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 0.8 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.8 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.7 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.6 GO:0070995 toxin metabolic process(GO:0009404) NADPH oxidation(GO:0070995)
0.1 0.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.2 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.0 0.2 GO:0000019 regulation of mitotic recombination(GO:0000019) telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 1.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.2 0.8 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.1 0.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.9 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.6 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks