Motif ID: Gcm1

Z-value: 0.628


Transcription factors associated with Gcm1:

Gene SymbolEntrez IDGene Name
Gcm1 ENSMUSG00000023333.7 Gcm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gcm1mm10_v2_chr9_+_78051938_780519580.097.1e-01Click!


Activity profile for motif Gcm1.

activity profile for motif Gcm1


Sorted Z-values histogram for motif Gcm1

Sorted Z-values for motif Gcm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gcm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_6065538 2.348 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr5_-_110343009 1.229 ENSMUST00000058016.9
ENSMUST00000112478.3
 P2rx2

purinergic receptor P2X, ligand-gated ion channel, 2

chr7_+_46396439 1.217 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr13_+_8202860 1.194 ENSMUST00000064473.6
 Adarb2
adenosine deaminase, RNA-specific, B2
chr19_+_6400523 1.156 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
 Rasgrp2



RAS, guanyl releasing protein 2



chr14_-_19977249 1.043 ENSMUST00000160013.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chrX_+_73503074 0.918 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
 Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr13_+_8202922 0.814 ENSMUST00000123187.1
 Adarb2
adenosine deaminase, RNA-specific, B2
chr4_-_136956784 0.789 ENSMUST00000030420.8
 Epha8
Eph receptor A8
chr16_-_91597636 0.787 ENSMUST00000023686.8
 Tmem50b
transmembrane protein 50B
chr3_-_69598822 0.723 ENSMUST00000061826.1
 B3galnt1
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
chr17_-_32189457 0.623 ENSMUST00000087721.3
ENSMUST00000162117.1
 Ephx3

epoxide hydrolase 3

chr1_-_79761752 0.616 ENSMUST00000113512.1
ENSMUST00000113513.1
ENSMUST00000113515.1
ENSMUST00000113514.1
ENSMUST00000113510.1
ENSMUST00000113511.1
ENSMUST00000048820.7
 Wdfy1






WD repeat and FYVE domain containing 1






chr16_-_3907651 0.575 ENSMUST00000177221.1
ENSMUST00000177323.1
 1700037C18Rik

RIKEN cDNA 1700037C18 gene

chr7_+_119900099 0.566 ENSMUST00000106516.1
 Lyrm1
LYR motif containing 1
chr9_-_70657121 0.552 ENSMUST00000049031.5
 Fam63b
family with sequence similarity 63, member B
chr2_+_96318014 0.550 ENSMUST00000135431.1
ENSMUST00000162807.2
 Lrrc4c

leucine rich repeat containing 4C

chr17_+_8311101 0.545 ENSMUST00000154553.1
 Sft2d1
SFT2 domain containing 1
chr10_-_13868779 0.508 ENSMUST00000105534.3
 Aig1
androgen-induced 1
chr7_-_99182681 0.506 ENSMUST00000033001.4
 Dgat2
diacylglycerol O-acyltransferase 2
chr11_-_75454656 0.485 ENSMUST00000173320.1
 Wdr81
WD repeat domain 81
chr10_-_76345254 0.480 ENSMUST00000036033.7
ENSMUST00000160048.1
ENSMUST00000105417.3
 Dip2a


DIP2 disco-interacting protein 2 homolog A (Drosophila)


chr11_-_106613370 0.461 ENSMUST00000128933.1
 Tex2
testis expressed gene 2
chr11_+_101246960 0.460 ENSMUST00000107282.3
 Ramp2
receptor (calcitonin) activity modifying protein 2
chr7_-_29906524 0.450 ENSMUST00000159920.1
ENSMUST00000162592.1
 Zfp27

zinc finger protein 27

chr13_+_100108155 0.395 ENSMUST00000129014.1
 Serf1
small EDRK-rich factor 1
chr11_-_60352869 0.387 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
 Tom1l2





target of myb1-like 2 (chicken)





chr7_+_4922251 0.387 ENSMUST00000047309.5
 Nat14
N-acetyltransferase 14
chr13_+_100107997 0.386 ENSMUST00000142155.1
ENSMUST00000022145.8
ENSMUST00000132053.1
 Serf1


small EDRK-rich factor 1


chr16_+_36875119 0.335 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
 Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr13_-_100108337 0.324 ENSMUST00000180822.1
 BC001981
cDNA sequence BC001981
chr6_+_6863769 0.317 ENSMUST00000031768.6
 Dlx6
distal-less homeobox 6
chr6_-_113501818 0.281 ENSMUST00000101059.1
 Prrt3
proline-rich transmembrane protein 3
chr2_+_48814109 0.252 ENSMUST00000063886.3
 Acvr2a
activin receptor IIA
chr19_+_53529100 0.248 ENSMUST00000038287.6
 Dusp5
dual specificity phosphatase 5
chr19_+_46761578 0.237 ENSMUST00000077666.4
ENSMUST00000099373.4
 Cnnm2

cyclin M2

chr12_+_8674224 0.226 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chr15_-_83251720 0.223 ENSMUST00000164614.1
ENSMUST00000049530.6
 A4galt

alpha 1,4-galactosyltransferase

chr7_+_131966446 0.218 ENSMUST00000045840.4
 Gpr26
G protein-coupled receptor 26
chr7_-_101011976 0.212 ENSMUST00000178340.1
ENSMUST00000037540.3
 P2ry2

purinergic receptor P2Y, G-protein coupled 2

chr14_+_55578360 0.197 ENSMUST00000174259.1
ENSMUST00000174563.1
ENSMUST00000089619.6
ENSMUST00000172738.1
 Psme1



proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)



chr19_+_6400611 0.193 ENSMUST00000113467.1
 Rasgrp2
RAS, guanyl releasing protein 2
chr13_-_95250166 0.181 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
 Pde8b



phosphodiesterase 8B



chr13_+_8202885 0.172 ENSMUST00000139438.1
ENSMUST00000135574.1
 Adarb2

adenosine deaminase, RNA-specific, B2

chr9_+_70656248 0.171 ENSMUST00000098589.2
 Gm10642
predicted gene 10642
chr15_-_10470490 0.167 ENSMUST00000136591.1
 Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr12_+_8674129 0.166 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
 Pum2


pumilio 2 (Drosophila)


chr4_-_156234777 0.121 ENSMUST00000105569.3
 Klhl17
kelch-like 17
chr14_+_32201937 0.114 ENSMUST00000163350.1
ENSMUST00000170840.1
ENSMUST00000022470.8
ENSMUST00000171279.1
 Parg



poly (ADP-ribose) glycohydrolase



chr17_-_32788284 0.107 ENSMUST00000159086.2
 Zfp871
zinc finger protein 871
chr8_+_91070052 0.096 ENSMUST00000034091.7
 Rbl2
retinoblastoma-like 2
chr10_-_71285234 0.093 ENSMUST00000020085.6
 Ube2d1
ubiquitin-conjugating enzyme E2D 1
chr17_-_6948283 0.090 ENSMUST00000024572.9
 Rsph3b
radial spoke 3B homolog (Chlamydomonas)
chr2_+_169633517 0.090 ENSMUST00000109157.1
 Tshz2
teashirt zinc finger family member 2
chr17_+_24696234 0.075 ENSMUST00000019464.7
 Noxo1
NADPH oxidase organizer 1
chr16_-_16869255 0.075 ENSMUST00000075017.4
 Vpreb1
pre-B lymphocyte gene 1
chr11_+_116918844 0.074 ENSMUST00000103027.3
 Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr16_-_36874806 0.062 ENSMUST00000075946.5
 Eaf2
ELL associated factor 2
chr11_-_121354337 0.061 ENSMUST00000106110.3
ENSMUST00000136797.1
ENSMUST00000026173.6
 Wdr45b


WD repeat domain 45B


chr15_+_79348061 0.043 ENSMUST00000163691.1
 Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr5_-_35105691 0.011 ENSMUST00000030986.8
 Lrpap1
low density lipoprotein receptor-related protein associated protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0032430 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.2 0.9 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 1.2 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.1 0.3 GO:0042713 sperm ejaculation(GO:0042713)
0.1 1.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.2 GO:0035106 operant conditioning(GO:0035106)
0.1 0.6 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 0.5 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 0.8 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.5 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.2 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 1.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0098543 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 2.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.2 GO:0030673 axolemma(GO:0030673)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) mercury ion binding(GO:0045340)
0.2 2.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.2 0.5 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.5 GO:0097643 amylin receptor activity(GO:0097643)
0.1 2.3 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.2 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.1 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.0 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.3 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.8 PID_EPHA_FWDPATHWAY EPHA forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 0.9 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.3 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.0 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.2 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL