Motif ID: Gmeb1

Z-value: 0.516


Transcription factors associated with Gmeb1:

Gene SymbolEntrez IDGene Name
Gmeb1 ENSMUSG00000028901.7 Gmeb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb1mm10_v2_chr4_-_132261596_1322616220.532.2e-02Click!


Activity profile for motif Gmeb1.

activity profile for motif Gmeb1


Sorted Z-values histogram for motif Gmeb1

Sorted Z-values for motif Gmeb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 85 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_83302817 1.479 ENSMUST00000142680.1
 Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr6_+_113531675 1.191 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr1_+_175880775 0.858 ENSMUST00000039725.6
 Exo1
exonuclease 1
chr2_-_157007015 0.715 ENSMUST00000146413.1
 Dsn1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr17_+_23679363 0.707 ENSMUST00000024699.2
 Cldn6
claudin 6
chr8_-_123949201 0.704 ENSMUST00000044795.7
 Nup133
nucleoporin 133
chr19_-_40588374 0.666 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
 Aldh18a1


aldehyde dehydrogenase 18 family, member A1


chr2_-_157007039 0.663 ENSMUST00000103129.2
ENSMUST00000103130.1
 Dsn1

DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)

chr19_+_43612299 0.640 ENSMUST00000057178.9
 Nkx2-3
NK2 homeobox 3
chr15_+_99074968 0.575 ENSMUST00000039665.6
 Troap
trophinin associated protein
chr3_-_138143352 0.566 ENSMUST00000098580.2
 Mttp
microsomal triglyceride transfer protein
chr4_-_126202583 0.544 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
 Thrap3


thyroid hormone receptor associated protein 3


chr4_-_135353126 0.539 ENSMUST00000030613.4
ENSMUST00000131373.1
 Srrm1

serine/arginine repetitive matrix 1

chr11_-_100822525 0.513 ENSMUST00000107358.2
 Stat5b
signal transducer and activator of transcription 5B
chr11_+_83302641 0.478 ENSMUST00000176430.1
ENSMUST00000065692.7
 Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr14_+_20694956 0.429 ENSMUST00000048016.1
 Fut11
fucosyltransferase 11
chr17_+_84511832 0.422 ENSMUST00000047206.5
 Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr5_-_31291026 0.404 ENSMUST00000041565.7
 Ift172
intraflagellar transport 172
chr18_+_36559972 0.401 ENSMUST00000134146.1
 Ankhd1
ankyrin repeat and KH domain containing 1
chr5_-_93206428 0.389 ENSMUST00000144514.1
 Ccni
cyclin I

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 1.4 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.4 1.2 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.2 1.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.9 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.7 GO:0098535 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
0.1 0.7 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 0.6 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.2 0.5 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.0 0.4 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.4 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.4 GO:0061525 hindgut development(GO:0061525) left/right axis specification(GO:0070986)
0.1 0.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:0003094 glomerular filtration(GO:0003094)
0.1 0.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 1.4 GO:0000939 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.1 0.7 GO:0098536 deuterosome(GO:0098536)
0.1 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0071004 U2 snRNP(GO:0005686) U2-type prespliceosome(GO:0071004)
0.1 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 GO:0030276 clathrin binding(GO:0030276)
0.4 1.2 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.1 1.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 0.9 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 0.7 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0032564 dATP binding(GO:0032564)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.5 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.4 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.2 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.2 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.7 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA