Motif ID: Hbp1

Z-value: 1.030


Transcription factors associated with Hbp1:

Gene SymbolEntrez IDGene Name
Hbp1 ENSMUSG00000002996.11 Hbp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hbp1mm10_v2_chr12_-_31950210_31950246-0.653.4e-03Click!


Activity profile for motif Hbp1.

activity profile for motif Hbp1


Sorted Z-values histogram for motif Hbp1

Sorted Z-values for motif Hbp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hbp1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_66852017 2.010 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr10_+_11609256 1.859 ENSMUST00000052902.7
 Gm9797
predicted pseudogene 9797
chr13_-_66851513 1.569 ENSMUST00000169322.1
 Gm17404
predicted gene, 17404
chr13_+_65512678 1.241 ENSMUST00000081471.2
 Gm10139
predicted gene 10139
chr5_+_139543889 1.176 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chrY_-_1245753 1.093 ENSMUST00000154004.1
 Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr6_-_23248264 1.089 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr10_+_14523062 1.054 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr19_-_32466575 1.053 ENSMUST00000078034.3
 Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr17_+_17402672 1.032 ENSMUST00000115576.2
 Lix1
limb expression 1 homolog (chicken)
chr10_-_92165159 1.007 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
 Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr7_-_75308373 0.917 ENSMUST00000085164.5
 Sv2b
synaptic vesicle glycoprotein 2 b
chr11_+_32276893 0.911 ENSMUST00000145569.1
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr19_-_53589067 0.908 ENSMUST00000095978.3
 Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr12_-_10900296 0.879 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chrM_+_7005 0.845 ENSMUST00000082405.1
 mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr19_+_24875679 0.838 ENSMUST00000073080.5
 Gm10053
predicted gene 10053
chr7_+_16452779 0.810 ENSMUST00000019302.8
 Tmem160
transmembrane protein 160
chr18_+_78349754 0.806 ENSMUST00000164064.1
 Gm6133
predicted gene 6133
chr10_+_57784914 0.784 ENSMUST00000165013.1
 Fabp7
fatty acid binding protein 7, brain

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 186 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 GO:0060134 prepulse inhibition(GO:0060134)
0.0 1.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 1.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 1.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 1.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 1.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.2 0.9 GO:0015671 oxygen transport(GO:0015671)
0.2 0.9 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0 0.9 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.9 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.9 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.2 0.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.8 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.8 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 0.7 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.2 0.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 78 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.4 GO:0070469 respiratory chain(GO:0070469)
0.2 1.3 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 0.8 GO:0030891 VCB complex(GO:0030891)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.7 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.6 GO:0005861 troponin complex(GO:0005861)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.6 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 127 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0051087 chaperone binding(GO:0051087)
0.0 1.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.4 1.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 1.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.8 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.8 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.7 GO:0031369 translation initiation factor binding(GO:0031369)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.0 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.8 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.6 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.6 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.6 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.6 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.4 PID_MYC_PATHWAY C-MYC pathway
0.0 0.4 PID_ATM_PATHWAY ATM pathway
0.0 0.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 2.3 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.4 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 1.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.0 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.9 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.8 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.7 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 0.6 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 0.6 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.6 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor