Motif ID: Hinfp

Z-value: 1.622


Transcription factors associated with Hinfp:

Gene SymbolEntrez IDGene Name
Hinfp ENSMUSG00000032119.4 Hinfp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hinfpmm10_v2_chr9_-_44305595_44305688-0.551.7e-02Click!


Activity profile for motif Hinfp.

activity profile for motif Hinfp


Sorted Z-values histogram for motif Hinfp

Sorted Z-values for motif Hinfp



Network of associatons between targets according to the STRING database.



First level regulatory network of Hinfp

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_106458440 5.333 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr11_-_89302545 5.247 ENSMUST00000061728.3
 Nog
noggin
chr19_+_25610533 4.675 ENSMUST00000048935.4
 Dmrt3
doublesex and mab-3 related transcription factor 3
chr4_-_106464167 3.904 ENSMUST00000049507.5
 Pcsk9
proprotein convertase subtilisin/kexin type 9
chr2_+_84840612 3.360 ENSMUST00000111625.1
 Slc43a1
solute carrier family 43, member 1
chrX_-_163761323 3.310 ENSMUST00000059320.2
 Rnf138rt1
ring finger protein 138, retrogene 1
chr3_+_87971129 3.166 ENSMUST00000160694.1
 Nes
nestin
chr3_+_87971071 3.102 ENSMUST00000090973.5
 Nes
nestin
chr11_-_90002881 2.991 ENSMUST00000020864.8
 Pctp
phosphatidylcholine transfer protein
chr7_+_46845832 2.907 ENSMUST00000048209.9
ENSMUST00000092621.4
 Ldha

lactate dehydrogenase A

chr14_-_48667508 2.897 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
 Otx2



orthodenticle homolog 2 (Drosophila)



chr9_-_77544870 2.827 ENSMUST00000183873.1
 Lrrc1
leucine rich repeat containing 1
chr2_-_91931675 2.748 ENSMUST00000111309.1
 Mdk
midkine
chr13_+_51645232 2.745 ENSMUST00000075853.5
 Cks2
CDC28 protein kinase regulatory subunit 2
chr17_-_15375969 2.698 ENSMUST00000014917.7
 Dll1
delta-like 1 (Drosophila)
chr19_-_4615647 2.694 ENSMUST00000113822.2
 Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr8_-_57487801 2.654 ENSMUST00000034022.3
 Sap30
sin3 associated polypeptide
chr11_+_80300866 2.536 ENSMUST00000017836.7
 Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr5_-_100674230 2.489 ENSMUST00000031262.7
 Coq2
coenzyme Q2 homolog, prenyltransferase (yeast)
chr9_+_62838767 2.445 ENSMUST00000034776.6
 Cln6
ceroid-lipofuscinosis, neuronal 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 175 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.8 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.1 5.3 GO:0001709 cell fate determination(GO:0001709)
1.3 5.2 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.4 4.7 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.9 4.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 4.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
1.0 3.9 GO:0001920 negative regulation of receptor recycling(GO:0001920) negative regulation of low-density lipoprotein particle clearance(GO:0010989) positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
0.2 3.6 GO:0051451 myoblast migration(GO:0051451)
0.1 3.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 3.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
1.0 3.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 3.1 GO:0018345 protein palmitoylation(GO:0018345)
0.7 2.9 GO:0006014 D-ribose metabolic process(GO:0006014)
0.7 2.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.6 2.9 GO:0019659 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 2.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 2.9 GO:0008203 cholesterol metabolic process(GO:0008203)
0.9 2.7 GO:0030421 defecation(GO:0030421)
0.9 2.7 GO:0001757 somite specification(GO:0001757) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
0.2 2.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.9 GO:0005643 nuclear pore(GO:0005643)
0.0 5.6 GO:0005667 transcription factor complex(GO:0005667)
1.3 3.9 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
1.2 3.7 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.1 3.7 GO:0005882 intermediate filament(GO:0005882)
0.5 3.6 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 3.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 3.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 2.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 2.8 GO:0000796 condensin complex(GO:0000796)
0.1 2.7 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 2.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 2.5 GO:0005787 signal peptidase complex(GO:0005787)
0.0 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.5 GO:0044291 cell-cell contact zone(GO:0044291)
0.4 2.4 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.0 2.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.8 2.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 2.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 126 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 6.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.7 6.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 4.8 GO:0019955 cytokine binding(GO:0019955)
1.0 4.0 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
1.3 3.9 GO:0034190 very-low-density lipoprotein particle binding(GO:0034189) apolipoprotein receptor binding(GO:0034190)
0.0 3.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 3.2 GO:0042393 histone binding(GO:0042393)
0.1 3.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 3.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 3.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.3 3.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 3.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 3.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.7 2.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 2.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.9 2.8 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.7 2.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 2.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 2.7 GO:0030957 Tat protein binding(GO:0030957)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.1 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 5.0 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.1 4.8 PID_BMP_PATHWAY BMP receptor signaling
0.1 4.2 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 3.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.5 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 3.0 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 3.0 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.5 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 2.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 2.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 2.0 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 1.4 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.4 PID_CD40_PATHWAY CD40/CD40L signaling
0.1 1.3 PID_MYC_PATHWAY C-MYC pathway
0.0 1.3 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.1 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.0 PID_NOTCH_PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.8 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 4.8 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 4.4 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 4.0 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 3.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 3.7 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 3.6 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.1 3.5 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.8 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 2.7 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.6 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.4 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.4 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 2.3 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.2 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 1.8 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.6 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.1 1.5 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.4 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway