Motif ID: Hmx3

Z-value: 0.241


Transcription factors associated with Hmx3:

Gene SymbolEntrez IDGene Name
Hmx3 ENSMUSG00000040148.5 Hmx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx3mm10_v2_chr7_+_131542867_1315428670.204.2e-01Click!


Activity profile for motif Hmx3.

activity profile for motif Hmx3


Sorted Z-values histogram for motif Hmx3

Sorted Z-values for motif Hmx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 51 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_53707532 0.736 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr3_-_154328634 0.374 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chrX_-_60893430 0.305 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr5_-_87482258 0.300 ENSMUST00000079811.6
ENSMUST00000144144.1
Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr2_-_72986716 0.270 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr17_-_35697971 0.237 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr10_-_80421847 0.224 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr4_-_129261394 0.208 ENSMUST00000145261.1
C77080
expressed sequence C77080
chr12_-_83921809 0.195 ENSMUST00000135962.1
ENSMUST00000155112.1
ENSMUST00000136848.1
ENSMUST00000126943.1
Numb



numb gene homolog (Drosophila)



chr1_-_158814469 0.189 ENSMUST00000161589.2
Pappa2
pappalysin 2
chrM_+_9452 0.188 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr2_+_3114220 0.168 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr4_+_154960915 0.163 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr1_+_110099295 0.154 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr1_-_78968079 0.149 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr3_-_86548268 0.135 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr1_-_175979114 0.117 ENSMUST00000104983.1
B020018G12Rik
RIKEN cDNA B020018G12 gene
chr5_+_121777929 0.115 ENSMUST00000160821.1
Atxn2
ataxin 2
chr1_-_190170671 0.114 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr13_+_23746734 0.113 ENSMUST00000099703.2
Hist1h2bb
histone cluster 1, H2bb

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.7 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.1 0.3 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.1 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
0.0 0.3 GO:0007530 sex determination(GO:0007530)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)

Gene overrepresentation in cellular_component category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.0 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)

Gene overrepresentation in molecular_function category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)