Motif ID: Hnf4g

Z-value: 1.174


Transcription factors associated with Hnf4g:

Gene SymbolEntrez IDGene Name
Hnf4g ENSMUSG00000017688.8 Hnf4g



Activity profile for motif Hnf4g.

activity profile for motif Hnf4g


Sorted Z-values histogram for motif Hnf4g

Sorted Z-values for motif Hnf4g



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf4g

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_88278085 1.039 ENSMUST00000032779.5
ENSMUST00000128791.1
Ctsc

cathepsin C

chr4_-_131838231 0.866 ENSMUST00000030741.2
ENSMUST00000105987.2
Ptpru

protein tyrosine phosphatase, receptor type, U

chr6_+_34354119 0.844 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr6_+_54326955 0.810 ENSMUST00000059138.4
Prr15
proline rich 15
chr7_+_45017953 0.801 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr16_-_18089022 0.770 ENSMUST00000132241.1
ENSMUST00000139861.1
ENSMUST00000003620.5
Prodh


proline dehydrogenase


chr8_+_94172618 0.715 ENSMUST00000034214.6
Mt2
metallothionein 2
chr15_-_86033777 0.711 ENSMUST00000016172.7
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr5_-_116422858 0.671 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr17_+_80127447 0.663 ENSMUST00000039205.4
Galm
galactose mutarotase
chr3_+_104789011 0.654 ENSMUST00000002303.5
ENSMUST00000106787.1
ENSMUST00000176347.1
Rhoc


ras homolog gene family, member C


chr11_-_115267236 0.640 ENSMUST00000106554.1
Grin2c
glutamate receptor, ionotropic, NMDA2C (epsilon 3)
chr11_+_105292637 0.636 ENSMUST00000100335.3
ENSMUST00000021038.4
Mrc2

mannose receptor, C type 2

chr9_+_64117147 0.633 ENSMUST00000034969.7
Lctl
lactase-like
chr2_-_105399286 0.613 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr18_-_39490649 0.612 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr3_+_146450467 0.609 ENSMUST00000061937.6
ENSMUST00000029840.3
Ctbs

chitobiase, di-N-acetyl-

chr12_-_75177325 0.602 ENSMUST00000042299.2
Kcnh5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr4_+_42240639 0.602 ENSMUST00000117202.2
Gm10600
predicted gene 10600
chr5_-_115119277 0.602 ENSMUST00000031524.7
Acads
acyl-Coenzyme A dehydrogenase, short chain

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 457 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 1.5 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 1.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.4 1.1 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 1.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.3 1.0 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.2 1.0 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.1 1.0 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 1.0 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 1.0 GO:0006289 nucleotide-excision repair(GO:0006289)
0.3 0.9 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.2 0.9 GO:0045608 inhibition of neuroepithelial cell differentiation(GO:0002085) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.1 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.9 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.9 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.3 0.8 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115)
0.2 0.8 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.8 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 175 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 1.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.9 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.9 GO:0001940 male pronucleus(GO:0001940)
0.1 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.8 GO:0005605 basal lamina(GO:0005605)
0.0 0.8 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.8 GO:0016234 inclusion body(GO:0016234)
0.2 0.7 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.1 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 299 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.1 GO:0051015 actin filament binding(GO:0051015)
0.2 1.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 1.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.4 1.1 GO:0005118 sevenless binding(GO:0005118)
0.1 1.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.0 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 1.0 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.1 1.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.0 GO:0019213 deacetylase activity(GO:0019213)
0.0 1.0 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.2 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 0.8 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.2 0.8 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2 0.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.6 PID_ATR_PATHWAY ATR signaling pathway
0.1 1.3 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 1.2 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.0 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.8 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.8 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.7 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 0.6 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.6 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 1.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.7 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.3 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.2 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.2 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.1 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.1 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.0 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 1.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.9 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.9 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.8 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import