Motif ID: Homez

Z-value: 0.789


Transcription factors associated with Homez:

Gene SymbolEntrez IDGene Name
Homez ENSMUSG00000057156.9 Homez

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Homezmm10_v2_chr14_-_54870913_54870961-0.341.7e-01Click!


Activity profile for motif Homez.

activity profile for motif Homez


Sorted Z-values histogram for motif Homez

Sorted Z-values for motif Homez



Network of associatons between targets according to the STRING database.



First level regulatory network of Homez

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 3.809 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr16_-_26989974 2.671 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr17_+_87635974 1.613 ENSMUST00000053577.8
 Epcam
epithelial cell adhesion molecule
chr18_+_86711059 1.547 ENSMUST00000068423.3
 Cbln2
cerebellin 2 precursor protein
chr18_+_50030977 1.384 ENSMUST00000145726.1
ENSMUST00000128377.1
 Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr9_+_91368811 1.362 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr18_-_62756275 1.188 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr9_+_91368970 1.178 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chr17_+_26542760 1.137 ENSMUST00000090257.4
 Gm8225
predicted gene 8225
chr11_+_101627942 1.069 ENSMUST00000010506.3
 Rdm1
RAD52 motif 1
chr4_+_44300876 1.014 ENSMUST00000045607.5
 Melk
maternal embryonic leucine zipper kinase
chr4_-_117178726 1.012 ENSMUST00000153953.1
ENSMUST00000106436.1
 Kif2c

kinesin family member 2C

chr1_+_169969409 0.944 ENSMUST00000180638.1
 3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr7_-_62464505 0.935 ENSMUST00000094339.2
 Peg12
paternally expressed 12
chr8_-_116921408 0.896 ENSMUST00000078589.6
ENSMUST00000148235.1
 Cmc2

COX assembly mitochondrial protein 2

chr5_-_87490869 0.890 ENSMUST00000147854.1
 Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr7_-_30664986 0.889 ENSMUST00000019697.8
 Haus5
HAUS augmin-like complex, subunit 5
chrX_+_20059535 0.887 ENSMUST00000044138.7
 Chst7
carbohydrate (N-acetylglucosamino) sulfotransferase 7
chr8_-_72305276 0.886 ENSMUST00000075602.6
 Gm10282
predicted pseudogene 10282
chr7_+_67647405 0.882 ENSMUST00000032774.8
ENSMUST00000107471.1
 Ttc23

tetratricopeptide repeat domain 23


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 2.8 GO:0006270 DNA replication initiation(GO:0006270)
0.4 1.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 1.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 1.4 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.4 1.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.2 1.3 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 1.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.3 GO:0032526 response to retinoic acid(GO:0032526)
0.0 1.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.2 1.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.0 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2 0.9 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.9 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.9 GO:0000578 embryonic axis specification(GO:0000578)
0.0 0.9 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.3 0.8 GO:0016598 protein arginylation(GO:0016598)
0.3 0.8 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.4 1.3 GO:0033193 Lsd1/2 complex(GO:0033193)
0.1 1.2 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 0.9 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 0.8 GO:0071817 MMXD complex(GO:0071817)
0.1 0.8 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.7 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.6 GO:0000243 commitment complex(GO:0000243)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 0.5 GO:1990423 RZZ complex(GO:1990423)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.3 GO:0008198 ferrous iron binding(GO:0008198)
0.2 1.2 GO:0042731 PH domain binding(GO:0042731)
0.0 1.2 GO:0070888 E-box binding(GO:0070888)
0.1 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 0.9 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 0.8 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.2 0.8 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.8 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)

Gene overrepresentation in C2:CP category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.8 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.6 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 0.5 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.8 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 2.6 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.6 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 1.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.3 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.2 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.0 REACTOME_KINESINS Genes involved in Kinesins
0.1 0.9 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 0.8 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.8 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.7 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.6 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 0.5 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis