---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_43730593	7.564	ENSMUST00000027217.8	1500015O10Rik	RIKEN cDNA 1500015O10 gene
chr17_+_35076902	7.396	ENSMUST00000172494.1 ENSMUST00000172678.1 ENSMUST00000013910.4	Ly6g6e	lymphocyte antigen 6 complex, locus G6E
chr1_-_56978534	6.102	ENSMUST00000177282.1	Satb2	special AT-rich sequence binding protein 2
chr17_+_6270475	4.792	ENSMUST00000088940.4	Tmem181a	transmembrane protein 181A
chr14_+_80000292	4.636	ENSMUST00000088735.3	Olfm4	olfactomedin 4
chr6_+_108213086	4.437	ENSMUST00000032192.6	Itpr1	inositol 1,4,5-trisphosphate receptor 1
chr13_+_16014457	4.103	ENSMUST00000164993.1	Inhba	inhibin beta-A
chr16_-_57231434	3.902	ENSMUST00000023431.6	Tbc1d23	TBC1 domain family, member 23
chr17_-_6477102	3.735	ENSMUST00000167717.2	Tmem181b-ps	transmembrane protein 181B, pseudogene
chr15_-_43869993	2.943	ENSMUST00000067469.4	Tmem74	transmembrane protein 74
chr11_-_62457772	2.589	ENSMUST00000127471.2	Ncor1	nuclear receptor co-repressor 1
chr17_+_22361453	2.501	ENSMUST00000149699.1 ENSMUST00000088765.2 ENSMUST00000072477.4 ENSMUST00000121315.1	Zfp758	zinc finger protein 758
chr14_+_27622433	2.449	ENSMUST00000090302.5	Erc2	ELKS/RAB6-interacting/CAST family member 2
chr18_+_69346143	2.375	ENSMUST00000114980.1	Tcf4	transcription factor 4
chr9_-_55919605	2.245	ENSMUST00000037408.8	Scaper	S phase cyclin A-associated protein in the ER
chr3_-_117360876	2.193	ENSMUST00000061071.8	D3Bwg0562e	DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr5_+_66968961	2.072	ENSMUST00000132991.1	Limch1	LIM and calponin homology domains 1
chr16_-_45408955	2.043	ENSMUST00000163230.1	Cd200	CD200 antigen
chrX_+_73064787	2.018	ENSMUST00000060418.6	Pnma3	paraneoplastic antigen MA3
chr2_-_180824596	1.989	ENSMUST00000148700.1	Gm14340	predicted gene 14340
chr11_-_115627948	1.749	ENSMUST00000154623.1 ENSMUST00000106503.3 ENSMUST00000141614.1	Slc25a19	solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr18_-_43393346	1.711	ENSMUST00000025379.7	Dpysl3	dihydropyrimidinase-like 3
chrX_+_41401128	1.585	ENSMUST00000115103.2	Gria3	glutamate receptor, ionotropic, AMPA3 (alpha 3)
chrX_+_41401304	1.584	ENSMUST00000076349.5	Gria3	glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr16_-_74411776	1.584	ENSMUST00000116586.2	Robo2	roundabout homolog 2 (Drosophila)
chr2_+_23068168	1.516	ENSMUST00000028121.7 ENSMUST00000114523.2 ENSMUST00000144088.1	Acbd5	acyl-Coenzyme A binding domain containing 5
chrX_+_20364481	1.437	ENSMUST00000033372.6 ENSMUST00000115391.1 ENSMUST00000115387.1	Rp2h	retinitis pigmentosa 2 homolog (human)
chr4_+_102741287	1.419	ENSMUST00000097948.2	Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1
chr7_-_73537621	1.413	ENSMUST00000172704.1	Chd2	chromodomain helicase DNA binding protein 2
chr13_+_109685994	1.411	ENSMUST00000074103.5	Pde4d	phosphodiesterase 4D, cAMP specific
chr11_-_115628125	1.341	ENSMUST00000155709.1 ENSMUST00000021089.4	Slc25a19	solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr6_-_118455475	1.308	ENSMUST00000161519.1 ENSMUST00000069292.7	Zfp248	zinc finger protein 248
chr9_+_3404058	1.284	ENSMUST00000027027.5	Cwf19l2	CWF19-like 2, cell cycle control (S. pombe)
chr6_+_96115249	1.209	ENSMUST00000075080.5	Fam19a1	family with sequence similarity 19, member A1
chrX_-_165004829	1.124	ENSMUST00000114890.2	Gm17604	predicted gene, 17604
chr18_+_37655891	1.109	ENSMUST00000097608.2	3222401L13Rik	RIKEN cDNA 3222401L13 gene
chr11_-_115628260	1.095	ENSMUST00000178003.1	Slc25a19	solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr9_+_53771499	1.045	ENSMUST00000048670.8	Slc35f2	solute carrier family 35, member F2
chr17_+_8283762	1.044	ENSMUST00000155364.1 ENSMUST00000046754.8 ENSMUST00000124023.1	Mpc1	mitochondrial pyruvate carrier 1
chr8_-_69625503	1.030	ENSMUST00000121886.1	Zfp868	zinc finger protein 868
chr3_+_79885930	1.018	ENSMUST00000029567.8	Fam198b	family with sequence similarity 198, member B
chr2_-_120970706	0.996	ENSMUST00000028728.5	Ubr1	ubiquitin protein ligase E3 component n-recognin 1
chr8_-_69373914	0.992	ENSMUST00000095282.1	Gm10311	predicted gene 10311
chr1_-_93101825	0.938	ENSMUST00000112958.2	Kif1a	kinesin family member 1A
chr19_+_5406815	0.928	ENSMUST00000174412.1 ENSMUST00000153017.2	4930481A15Rik	RIKEN cDNA 4930481A15 gene
chr13_-_12464925	0.866	ENSMUST00000124888.1	Lgals8	lectin, galactose binding, soluble 8
chr10_+_90071095	0.846	ENSMUST00000183109.1	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr8_+_104250925	0.832	ENSMUST00000098464.4	Cklf	chemokine-like factor
chr1_-_189922338	0.818	ENSMUST00000027897.7	Smyd2	SET and MYND domain containing 2
chr3_+_32436376	0.784	ENSMUST00000108242.1	Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr5_-_73256555	0.771	ENSMUST00000101127.5 ENSMUST00000171179.1	Fryl Fryl	furry homolog-like (Drosophila) furry homolog-like (Drosophila)
chr18_-_46280820	0.761	ENSMUST00000025354.3	Pggt1b	protein geranylgeranyltransferase type I, beta subunit
chr15_-_101850778	0.731	ENSMUST00000023790.3	Krt1	keratin 1
chr13_+_98263105	0.729	ENSMUST00000150916.1	Ankra2	ankyrin repeat, family A (RFXANK-like), 2
chr16_-_16600533	0.725	ENSMUST00000159542.1	Fgd4	FYVE, RhoGEF and PH domain containing 4
chr12_-_23780265	0.715	ENSMUST00000072014.4	Gm10330	predicted gene 10330
chr13_-_54749849	0.689	ENSMUST00000135343.1	Gprin1	G protein-regulated inducer of neurite outgrowth 1
chr3_+_66219909	0.687	ENSMUST00000029421.5	Ptx3	pentraxin related gene
chr18_+_37333853	0.683	ENSMUST00000061717.2	Pcdhb6	protocadherin beta 6
chr5_-_20951769	0.680	ENSMUST00000036489.5	Rsbn1l	round spermatid basic protein 1-like
chr11_+_77216180	0.661	ENSMUST00000037912.5 ENSMUST00000156488.1	Ssh2	slingshot homolog 2 (Drosophila)
chr7_-_46795661	0.661	ENSMUST00000123725.1	Hps5	Hermansky-Pudlak syndrome 5 homolog (human)
chr13_-_66851513	0.630	ENSMUST00000169322.1	Gm17404	predicted gene, 17404
chr12_+_78226627	0.608	ENSMUST00000110388.2 ENSMUST00000052472.4	Gphn	gephyrin
chr19_+_58943413	0.608	ENSMUST00000054280.6	Eno4	enolase 4
chr18_-_38209762	0.584	ENSMUST00000057185.6	Pcdh1	protocadherin 1
chr12_+_59066908	0.565	ENSMUST00000021381.4	Pnn	pinin
chr17_-_24455265	0.561	ENSMUST00000056032.7	E4f1	E4F transcription factor 1
chr16_+_23224724	0.556	ENSMUST00000023601.7	St6gal1	beta galactoside alpha 2,6 sialyltransferase 1
chr8_+_40307458	0.555	ENSMUST00000068999.7	Micu3	mitochondrial calcium uptake family, member 3
chr3_-_88458876	0.545	ENSMUST00000147200.1 ENSMUST00000169222.1	Sema4a	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_+_75592844	0.543	ENSMUST00000114249.1 ENSMUST00000046378.7 ENSMUST00000114253.1	Rbm11	RNA binding motif protein 11
chr16_-_23225334	0.533	ENSMUST00000055369.4	BC106179	cDNA sequence BC106179
chr13_+_98263242	0.525	ENSMUST00000022164.8 ENSMUST00000150352.1	Ankra2	ankyrin repeat, family A (RFXANK-like), 2
chr6_+_42286709	0.524	ENSMUST00000163936.1	Clcn1	chloride channel 1
chr11_-_95309557	0.522	ENSMUST00000092766.5 ENSMUST00000072621.5	Kat7	K(lysine) acetyltransferase 7
chr6_+_91878034	0.511	ENSMUST00000037783.5	Ccdc174	coiled-coil domain containing 174
chr2_-_104712122	0.486	ENSMUST00000111118.1 ENSMUST00000028597.3	Tcp11l1	t-complex 11 like 1
chr6_-_87809757	0.485	ENSMUST00000032134.7	Rab43	RAB43, member RAS oncogene family
chr13_+_98263187	0.479	ENSMUST00000091356.3 ENSMUST00000123924.1	Ankra2	ankyrin repeat, family A (RFXANK-like), 2
chr3_-_88459047	0.472	ENSMUST00000165898.1 ENSMUST00000127436.1	Sema4a	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_+_87354185	0.461	ENSMUST00000054442.4 ENSMUST00000118310.1 ENSMUST00000120284.1 ENSMUST00000118115.1	N6amt1	N-6 adenine-specific DNA methyltransferase 1 (putative)
chr14_-_34503323	0.450	ENSMUST00000171343.1	Bmpr1a	bone morphogenetic protein receptor, type 1A
chr5_+_32611171	0.450	ENSMUST00000072311.6 ENSMUST00000168707.2	Yes1	Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
chr7_+_4460687	0.424	ENSMUST00000167298.1 ENSMUST00000171445.1	Eps8l1	EPS8-like 1
chr3_+_129532386	0.408	ENSMUST00000071402.2	Elovl6	ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr6_+_42286676	0.397	ENSMUST00000031894.6	Clcn1	chloride channel 1
chr4_-_129378116	0.397	ENSMUST00000030610.2	Zbtb8a	zinc finger and BTB domain containing 8a
chr11_+_55213783	0.388	ENSMUST00000108867.1	Slc36a1	solute carrier family 36 (proton/amino acid symporter), member 1
chr3_+_126597415	0.384	ENSMUST00000066452.7 ENSMUST00000171289.1 ENSMUST00000106399.1	Camk2d	calcium/calmodulin-dependent protein kinase II, delta
chr5_-_123666682	0.361	ENSMUST00000149410.1	Clip1	CAP-GLY domain containing linker protein 1
chr7_+_100372224	0.353	ENSMUST00000051777.8 ENSMUST00000098259.4	C2cd3	C2 calcium-dependent domain containing 3
chr5_-_116024475	0.347	ENSMUST00000111999.1	Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr7_-_46795881	0.344	ENSMUST00000107653.1 ENSMUST00000107654.1 ENSMUST00000014562.7 ENSMUST00000152759.1	Hps5	Hermansky-Pudlak syndrome 5 homolog (human)
chr11_-_62789402	0.341	ENSMUST00000108705.1	Zfp286	zinc finger protein 286
chr14_-_104522615	0.335	ENSMUST00000022716.2	Rnf219	ring finger protein 219
chr4_+_108328136	0.330	ENSMUST00000131656.1	Selrc1	Sel1 repeat containing 1
chr13_-_66852017	0.329	ENSMUST00000059329.6	Gm17449	predicted gene, 17449
chr6_-_55681257	0.323	ENSMUST00000044767.8	Neurod6	neurogenic differentiation 6
chr11_-_62789445	0.312	ENSMUST00000054654.6	Zfp286	zinc finger protein 286
chr10_-_120979327	0.307	ENSMUST00000119944.1 ENSMUST00000119093.1	Lemd3	LEM domain containing 3
chr1_+_178529113	0.298	ENSMUST00000161017.1	Kif26b	kinesin family member 26B
chr12_-_27160311	0.296	ENSMUST00000182473.1 ENSMUST00000177636.1 ENSMUST00000183238.1	Gm9866	predicted gene 9866
chr7_+_43634718	0.278	ENSMUST00000032663.8	Ceacam18	carcinoembryonic antigen-related cell adhesion molecule 18
chr13_-_23430826	0.268	ENSMUST00000153753.1 ENSMUST00000141543.1	C230035I16Rik	RIKEN cDNA C230035I16 gene
chr7_-_141435327	0.254	ENSMUST00000138865.1	Slc25a22	solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr12_-_20900867	0.224	ENSMUST00000079237.5	Zfp125	zinc finger protein 125
chr6_-_29216301	0.207	ENSMUST00000162739.1 ENSMUST00000162099.1 ENSMUST00000159124.1	Impdh1	inosine 5'-phosphate dehydrogenase 1
chr15_+_85510812	0.200	ENSMUST00000079690.2	Gm4825	predicted pseudogene 4825
chr6_-_29216277	0.183	ENSMUST00000162215.1	Impdh1	inosine 5'-phosphate dehydrogenase 1
chr3_+_88621102	0.155	ENSMUST00000029694.7 ENSMUST00000176804.1	Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2
chr11_-_43426192	0.154	ENSMUST00000101340.4 ENSMUST00000118368.1 ENSMUST00000020685.9 ENSMUST00000020687.8	Pttg1	pituitary tumor-transforming gene 1
chr3_+_126597299	0.147	ENSMUST00000106400.2 ENSMUST00000106401.1	Camk2d	calcium/calmodulin-dependent protein kinase II, delta
chr11_-_72267141	0.145	ENSMUST00000137701.1	Slc13a5	solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr14_+_49172202	0.134	ENSMUST00000153488.1	Naa30	N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr2_+_166805506	0.134	ENSMUST00000099078.3	Arfgef2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr1_+_182409162	0.119	ENSMUST00000117245.1	Trp53bp2	transformation related protein 53 binding protein 2
chr5_-_143292356	0.113	ENSMUST00000180336.1	Zfp853	zinc finger protein 853
chr8_+_31150307	0.106	ENSMUST00000098842.2	Tti2	TELO2 interacting protein 2
chr7_-_141434532	0.097	ENSMUST00000133021.1 ENSMUST00000106007.3 ENSMUST00000150026.1 ENSMUST00000133206.2	Slc25a22	solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr13_-_99344652	0.095	ENSMUST00000022153.6	Ptcd2	pentatricopeptide repeat domain 2
chr8_+_105225145	0.086	ENSMUST00000034361.3	D230025D16Rik	RIKEN cDNA D230025D16 gene
chr19_-_7341848	0.035	ENSMUST00000171393.1	Mark2	MAP/microtubule affinity-regulating kinase 2
chr11_-_5542177	0.028	ENSMUST00000020776.4	Ccdc117	coiled-coil domain containing 117

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.2	GO:0030974	thiamine pyrophosphate transport(GO:0030974)
0.9	7.6	GO:0070314	G1 to G0 transition(GO:0070314)
0.8	4.1	GO:0042636	negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.8	4.8	GO:0009405	pathogenesis(GO:0009405)
0.7	4.4	GO:0042045	epithelial fluid transport(GO:0042045)
0.7	2.0	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.6	2.6	GO:0072362	regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.5	1.6	GO:0050925	negative regulation of negative chemotaxis(GO:0050925)
0.4	6.1	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3	0.8	GO:0044028	DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.3	1.0	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.3	7.4	GO:0022401	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.3	0.8	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.2	1.0	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2	1.5	GO:0030242	pexophagy(GO:0030242)
0.2	2.4	GO:0042118	endothelial cell activation(GO:0042118)
0.2	0.5	GO:0072720	response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.2	0.5	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2	1.4	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.2	0.5	GO:0021998	neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.1	0.9	GO:0002317	plasma cell differentiation(GO:0002317)
0.1	0.6	GO:2000110	protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.1	0.7	GO:0052428	modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1	0.6	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1	0.8	GO:0090527	actin filament reorganization(GO:0090527)
0.1	1.4	GO:1901898	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1	0.5	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.1	0.7	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.8	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	4.6	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1	0.3	GO:0072092	ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.1	0.6	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1	0.9	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1	0.4	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
0.1	1.7	GO:0051764	actin crosslink formation(GO:0051764)
0.1	0.7	GO:0030035	microspike assembly(GO:0030035)
0.1	0.4	GO:0006177	GMP biosynthetic process(GO:0006177)
0.1	3.2	GO:0001919	regulation of receptor recycling(GO:0001919)
0.1	0.4	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.1	0.4	GO:0061511	centriole elongation(GO:0061511)
0.1	0.8	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1	0.9	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	0.3	GO:0070197	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1	0.4	GO:0015808	L-alanine transport(GO:0015808)
0.1	4.1	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.1	1.0	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.0	0.4	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0015744	succinate transport(GO:0015744)
0.0	0.2	GO:0035878	nail development(GO:0035878)
0.0	0.4	GO:0036120	cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0	0.6	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.8	GO:0048246	macrophage chemotaxis(GO:0048246)
0.0	0.7	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.7	GO:0009988	cell-cell recognition(GO:0009988)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.3	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.3	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	2.9	GO:0016236	macroautophagy(GO:0016236)
0.0	0.4	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.1	GO:0001881	receptor recycling(GO:0001881)
0.0	0.5	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.6	GO:0030317	sperm motility(GO:0030317)
0.0	0.1	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	1.0	GO:0043473	pigmentation(GO:0043473)
0.0	2.1	GO:0031032	actomyosin structure organization(GO:0031032)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	4.4	GO:0031088	platelet dense granule membrane(GO:0031088)
1.4	4.1	GO:0043512	inhibin A complex(GO:0043512)
0.4	7.6	GO:0031045	dense core granule(GO:0031045)
0.4	4.6	GO:0042581	specific granule(GO:0042581)
0.3	1.7	GO:1990393	3M complex(GO:1990393)
0.3	0.8	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.3	1.0	GO:0031084	BLOC-2 complex(GO:0031084)
0.2	3.2	GO:0043083	synaptic cleft(GO:0043083)
0.2	5.2	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.1	0.7	GO:0001533	cornified envelope(GO:0001533)
0.1	2.6	GO:0016580	Sin3 complex(GO:0016580)
0.1	1.4	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.1	6.1	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	0.6	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.6	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.4	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	0.6	GO:0030057	desmosome(GO:0030057)
0.0	2.4	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	1.6	GO:0030673	axolemma(GO:0030673)
0.0	1.9	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0032280	symmetric synapse(GO:0032280)
0.0	1.7	GO:0031941	filamentous actin(GO:0031941)
0.0	0.9	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.6	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.3	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	2.0	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.4	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	1.0	GO:0000502	proteasome complex(GO:0000502)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	7.4	GO:0030549	acetylcholine receptor activator activity(GO:0030549)
1.5	4.4	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.7	4.2	GO:0015234	thiamine transmembrane transporter activity(GO:0015234)
0.7	4.1	GO:0070699	type II activin receptor binding(GO:0070699)
0.6	2.4	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5	3.2	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.4	4.8	GO:0015643	toxic substance binding(GO:0015643)
0.3	2.6	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.3	1.0	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.2	1.7	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.2	1.6	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	1.0	GO:0070728	leucine binding(GO:0070728)
0.2	0.8	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.2	0.6	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.1	0.8	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.4	GO:0015173	hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1	0.6	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1	0.7	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.8	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.4	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.1	0.6	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.5	GO:0031432	titin binding(GO:0031432)
0.1	0.5	GO:0098821	BMP receptor activity(GO:0098821)
0.1	0.8	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	1.7	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	1.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.5	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.4	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	1.1	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.6	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.4	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.5	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.4	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.6	GO:0008009	chemokine activity(GO:0008009)
0.0	0.2	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	2.5	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.8	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.4	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.7	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	6.6	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	2.8	GO:0008017	microtubule binding(GO:0008017)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.0	ST_WNT_CA2_CYCLIC_GMP_PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	4.1	PID_ALK1_PATHWAY	ALK1 signaling events
0.1	3.4	PID_ERBB4_PATHWAY	ErbB4 signaling events
0.0	1.7	PID_HDAC_CLASSII_PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.7	ST_MYOCYTE_AD_PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	2.5	PID_BETA_CATENIN_NUC_PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.4	PID_GLYPICAN_1PATHWAY	Glypican 1 network
0.0	1.9	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.5	PID_BMP_PATHWAY	BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.1	REACTOME_GLYCOPROTEIN_HORMONES	Genes involved in Glycoprotein hormones
0.1	3.7	REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	2.6	REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.7	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	0.2	REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	2.4	REACTOME_MYOGENESIS	Genes involved in Myogenesis
0.1	0.6	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	1.2	REACTOME_REGULATION_OF_SIGNALING_BY_CBL	Genes involved in Regulation of signaling by CBL
0.0	1.0	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.6	REACTOME_SIGNALING_BY_ROBO_RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	1.4	REACTOME_DARPP_32_EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME_SIGNALING_BY_BMP	Genes involved in Signaling by BMP
0.0	0.9	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE	Genes involved in Amino acid transport across the plasma membrane

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