Motif ID: Hoxa13

Z-value: 0.783


Transcription factors associated with Hoxa13:

Gene SymbolEntrez IDGene Name
Hoxa13 ENSMUSG00000038203.12 Hoxa13



Activity profile for motif Hoxa13.

activity profile for motif Hoxa13


Sorted Z-values histogram for motif Hoxa13

Sorted Z-values for motif Hoxa13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa13

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_-_1286563 2.173 ENSMUST00000091190.5
 Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chrX_+_106920618 1.312 ENSMUST00000060576.7
 Lpar4
lysophosphatidic acid receptor 4
chr19_+_44493472 1.305 ENSMUST00000041163.4
 Wnt8b
wingless related MMTV integration site 8b
chrY_+_897782 1.261 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr19_-_5796924 1.161 ENSMUST00000174808.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr2_+_126215100 1.149 ENSMUST00000164042.2
 Gm17555
predicted gene, 17555
chr3_+_137671524 1.040 ENSMUST00000166899.2
 Gm21962
predicted gene, 21962
chr10_-_116972609 0.999 ENSMUST00000092165.4
 Gm10271
predicted gene 10271
chr14_+_73661225 0.990 ENSMUST00000098874.3
 Gm21750
predicted gene, 21750
chr16_+_15317458 0.944 ENSMUST00000178312.1
 Gm21897
predicted gene, 21897
chr16_+_82828382 0.941 ENSMUST00000177665.1
 Gm21833
predicted gene, 21833
chr16_-_26989974 0.925 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr5_+_139543889 0.868 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr1_+_137928100 0.813 ENSMUST00000054333.2
 A130050O07Rik
RIKEN cDNA A130050O07 gene
chr11_+_108587077 0.803 ENSMUST00000146912.2
 Cep112
centrosomal protein 112
chr9_-_21067093 0.795 ENSMUST00000115494.2
 Zglp1
zinc finger, GATA-like protein 1
chr7_+_30565410 0.783 ENSMUST00000043850.7
 Igflr1
IGF-like family receptor 1
chr2_-_18048347 0.777 ENSMUST00000066885.5
 Skida1
SKI/DACH domain containing 1
chrX_-_109013389 0.755 ENSMUST00000033597.8
 Hmgn5
high-mobility group nucleosome binding domain 5
chr12_-_54986328 0.735 ENSMUST00000038926.6
 Baz1a
bromodomain adjacent to zinc finger domain 1A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.4 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.3 1.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 1.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 1.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 1.0 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 0.9 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.9 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.8 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.8 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.8 GO:0048599 oocyte development(GO:0048599)
0.0 0.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.7 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.7 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.4 GO:0008623 CHRAC(GO:0008623)
0.4 1.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.3 GO:0070469 respiratory chain(GO:0070469)
0.3 1.0 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.5 GO:0070820 tertiary granule(GO:0070820)
0.1 0.5 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.4 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.4 GO:0090537 CERF complex(GO:0090537)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.3 1.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 1.3 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.2 1.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.2 1.0 GO:0050436 microfibril binding(GO:0050436)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.6 GO:0000150 recombinase activity(GO:0000150)
0.2 0.5 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.8 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.0 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 1.1 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 0.5 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.5 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.3 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins