Motif ID: Hoxa2

Z-value: 1.153


Transcription factors associated with Hoxa2:

Gene SymbolEntrez IDGene Name
Hoxa2 ENSMUSG00000014704.8 Hoxa2



Activity profile for motif Hoxa2.

activity profile for motif Hoxa2


Sorted Z-values histogram for motif Hoxa2

Sorted Z-values for motif Hoxa2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_139543889 5.671 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr16_-_23890805 4.780 ENSMUST00000004480.3
Sst
somatostatin
chr12_+_109747903 3.114 ENSMUST00000183084.1
ENSMUST00000182300.1
Mirg

miRNA containing gene

chr2_-_117342949 3.097 ENSMUST00000102534.4
Rasgrp1
RAS guanyl releasing protein 1
chr2_-_117342831 2.925 ENSMUST00000178884.1
Rasgrp1
RAS guanyl releasing protein 1
chr2_-_117342709 2.724 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
Rasgrp1


RAS guanyl releasing protein 1


chr8_-_87959560 2.521 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr8_-_4779513 2.511 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr13_+_117220584 2.434 ENSMUST00000022242.7
Emb
embigin
chr14_-_34374617 2.326 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr7_+_144838590 2.305 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chrX_-_103483205 2.217 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr10_-_92162753 2.204 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr11_-_58801944 2.169 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b

family with sequence similarity 183, member B

chr1_-_133907053 2.015 ENSMUST00000149380.1
ENSMUST00000124051.2
Optc

opticin

chr9_-_106158109 2.000 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr4_+_46450892 1.943 ENSMUST00000102926.4
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr9_+_51621425 1.915 ENSMUST00000089534.4
Gm7293
predicted gene 7293
chr14_-_61037937 1.900 ENSMUST00000111236.2
Tnfrsf19
tumor necrosis factor receptor superfamily, member 19
chr5_-_24527276 1.890 ENSMUST00000088311.4
Gbx1
gastrulation brain homeobox 1
chr5_+_115235836 1.878 ENSMUST00000081497.6
Pop5
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr1_-_133906973 1.825 ENSMUST00000126123.1
Optc
opticin
chr2_-_84775420 1.794 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr6_+_5390387 1.788 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr4_-_92191749 1.787 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr2_-_84775388 1.724 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr9_-_21760275 1.721 ENSMUST00000098942.4
Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr17_-_32166879 1.693 ENSMUST00000087723.3
Notch3
notch 3
chr7_+_45163915 1.659 ENSMUST00000085374.5
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr10_-_96409038 1.565 ENSMUST00000179683.1
Gm20091
predicted gene, 20091
chr8_-_110902442 1.534 ENSMUST00000041382.6
Fuk
fucokinase
chr15_+_39006272 1.526 ENSMUST00000179165.1
ENSMUST00000022906.7
Fzd6

frizzled homolog 6 (Drosophila)

chr4_+_105790534 1.490 ENSMUST00000185012.1
Gm12728
predicted gene 12728
chr16_+_92498122 1.468 ENSMUST00000023670.3
Clic6
chloride intracellular channel 6
chr19_+_24875679 1.455 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr17_-_53539411 1.429 ENSMUST00000056198.3
Pp2d1
protein phosphatase 2C-like domain containing 1
chr14_+_11227511 1.426 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr15_+_79030874 1.401 ENSMUST00000171999.1
ENSMUST00000006544.7
Gcat

glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)

chr11_-_100356116 1.399 ENSMUST00000138603.2
Hap1
huntingtin-associated protein 1
chr19_-_10203880 1.392 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr3_+_55782500 1.392 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr2_-_69206133 1.389 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr15_-_81729864 1.340 ENSMUST00000171115.1
ENSMUST00000170134.1
ENSMUST00000052374.5
Rangap1


RAN GTPase activating protein 1


chrX_+_96455359 1.326 ENSMUST00000033553.7
Heph
hephaestin
chr3_-_157925056 1.310 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr2_+_156840966 1.307 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr15_-_55548164 1.251 ENSMUST00000165356.1
Mrpl13
mitochondrial ribosomal protein L13
chr10_-_95673451 1.250 ENSMUST00000099328.1
Anapc15-ps
anaphase prompoting complex C subunit 15, pseudogene
chr4_+_116596672 1.241 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chr7_+_100537192 1.225 ENSMUST00000120454.1
Coa4
cytochrome c oxidase assembly factor 4
chr13_-_97099296 1.220 ENSMUST00000071118.4
Gm6169
predicted gene 6169
chr3_-_116253467 1.219 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr12_+_108334341 1.218 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr7_-_127260677 1.210 ENSMUST00000035276.4
Dctpp1
dCTP pyrophosphatase 1
chr4_+_134510999 1.205 ENSMUST00000105866.2
Aunip
aurora kinase A and ninein interacting protein
chr18_-_61259987 1.200 ENSMUST00000170335.2
Rps2-ps10
ribosomal protein S2, pseudogene 10
chr2_-_69206146 1.155 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr9_+_15520830 1.147 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr2_+_103957976 1.145 ENSMUST00000156813.1
ENSMUST00000170926.1
Lmo2

LIM domain only 2

chr7_+_100495987 1.124 ENSMUST00000133044.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr4_+_15881255 1.122 ENSMUST00000029876.1
Calb1
calbindin 1
chr15_+_59648350 1.121 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr2_-_149798701 1.101 ENSMUST00000148202.1
ENSMUST00000139471.1
Gm14133

predicted gene 14133

chr15_-_78773452 1.088 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr18_-_20682963 1.062 ENSMUST00000165229.2
Gm10269
predicted gene 10269
chr5_-_30945393 1.050 ENSMUST00000031051.6
Cgref1
cell growth regulator with EF hand domain 1
chr6_+_4504814 1.048 ENSMUST00000141483.1
Col1a2
collagen, type I, alpha 2
chr11_-_106998483 1.046 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chrX_-_134161928 1.023 ENSMUST00000033611.4
Xkrx
X Kell blood group precursor related X linked
chr10_-_63421739 1.022 ENSMUST00000054760.4
Gm7075
predicted gene 7075
chrX_+_56779699 1.006 ENSMUST00000114772.2
ENSMUST00000114768.3
ENSMUST00000155882.1
Fhl1


four and a half LIM domains 1


chr3_-_37125943 1.005 ENSMUST00000029275.5
Il2
interleukin 2
chr14_-_13961202 1.000 ENSMUST00000065865.8
Thoc7
THO complex 7 homolog (Drosophila)
chr5_-_98566762 0.998 ENSMUST00000086912.4
1700010H22Rik
RIKEN cDNA 1700010H22 gene
chr11_-_100356078 0.978 ENSMUST00000103124.4
Hap1
huntingtin-associated protein 1
chr2_+_30845059 0.974 ENSMUST00000041659.5
Prrx2
paired related homeobox 2
chr5_-_130024280 0.971 ENSMUST00000161640.1
ENSMUST00000161884.1
ENSMUST00000161094.1
Asl


argininosuccinate lyase


chr1_-_119053619 0.971 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr3_+_32708546 0.960 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr7_+_142460834 0.956 ENSMUST00000018963.4
ENSMUST00000105967.1
Lsp1

lymphocyte specific 1

chr3_+_134828993 0.955 ENSMUST00000029822.4
Tacr3
tachykinin receptor 3
chr5_+_92683625 0.954 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr9_-_73968901 0.953 ENSMUST00000184666.1
Unc13c
unc-13 homolog C (C. elegans)
chr17_+_46496753 0.951 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr3_-_150073620 0.939 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr9_-_71485893 0.939 ENSMUST00000034720.5
Polr2m
polymerase (RNA) II (DNA directed) polypeptide M
chr14_-_122913085 0.938 ENSMUST00000162164.1
ENSMUST00000110679.2
ENSMUST00000038075.5
Ggact


gamma-glutamylamine cyclotransferase


chr17_+_66123520 0.935 ENSMUST00000163605.2
Ddx11
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr17_+_78491549 0.932 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr3_-_92429403 0.925 ENSMUST00000047300.7
Gm9774
predicted pseudogene 9774
chr15_-_84447037 0.925 ENSMUST00000080751.2
1810041L15Rik
RIKEN cDNA 1810041L15 gene
chr2_-_101883010 0.919 ENSMUST00000154525.1
Prr5l
proline rich 5 like
chr10_-_128804353 0.912 ENSMUST00000051011.7
Tmem198b
transmembrane protein 198b
chrM_+_7759 0.912 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chrM_+_11734 0.909 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr2_-_126709567 0.902 ENSMUST00000099423.2
Gm10774
predicted pseudogene 10774
chr15_-_102350692 0.899 ENSMUST00000041208.7
Aaas
achalasia, adrenocortical insufficiency, alacrimia
chr11_+_94327984 0.899 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr3_+_85915722 0.881 ENSMUST00000054148.7
Gm9790
predicted gene 9790
chr4_+_100776664 0.869 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr6_-_24527546 0.844 ENSMUST00000118558.1
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr13_+_108670576 0.838 ENSMUST00000074680.6
Rps3a3
ribosomal protein S3A3
chr8_-_105471481 0.837 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr4_-_35157404 0.827 ENSMUST00000102975.3
Mob3b
MOB kinase activator 3B
chr10_+_4611971 0.821 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr3_+_89266552 0.820 ENSMUST00000040824.1
Dpm3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr10_-_81349085 0.819 ENSMUST00000141171.1
Hmg20b
high mobility group 20B
chr9_+_58129476 0.813 ENSMUST00000133287.1
Stra6
stimulated by retinoic acid gene 6
chr13_-_97760588 0.812 ENSMUST00000074072.3
Gm10260
predicted gene 10260
chr13_+_23575753 0.811 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr9_-_85327110 0.805 ENSMUST00000034802.8
Fam46a
family with sequence similarity 46, member A
chrX_-_102157065 0.794 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr9_+_58129062 0.794 ENSMUST00000085677.2
Stra6
stimulated by retinoic acid gene 6
chr4_-_43653542 0.787 ENSMUST00000084646.4
Spag8
sperm associated antigen 8
chr9_+_58134017 0.784 ENSMUST00000134955.1
ENSMUST00000147134.1
ENSMUST00000170397.1
Stra6


stimulated by retinoic acid gene 6


chr9_+_58129321 0.784 ENSMUST00000034880.3
Stra6
stimulated by retinoic acid gene 6
chr12_+_87443896 0.783 ENSMUST00000161023.1
ENSMUST00000160488.1
ENSMUST00000077462.7
ENSMUST00000160880.1
Slirp



SRA stem-loop interacting RNA binding protein



chr17_+_24426676 0.780 ENSMUST00000024946.5
Eci1
enoyl-Coenzyme A delta isomerase 1
chr17_-_71310952 0.778 ENSMUST00000024849.9
Emilin2
elastin microfibril interfacer 2
chr6_+_14901344 0.777 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr12_-_87444017 0.775 ENSMUST00000091090.4
2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr15_+_31224371 0.754 ENSMUST00000044524.9
Dap
death-associated protein
chr17_-_71002488 0.741 ENSMUST00000148960.1
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr3_+_122044428 0.731 ENSMUST00000013995.8
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr7_-_27985796 0.729 ENSMUST00000099111.3
Zfp850
zinc finger protein 850
chr10_-_88605017 0.712 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr8_-_89187560 0.709 ENSMUST00000093326.2
Gm5356
predicted pseudogene 5356
chr16_+_38346986 0.709 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
Cox17

Gm21987
cytochrome c oxidase assembly protein 17

predicted gene 21987
chr7_+_27473761 0.702 ENSMUST00000068641.6
Sertad3
SERTA domain containing 3
chrM_-_14060 0.697 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr17_-_25880236 0.695 ENSMUST00000176696.1
ENSMUST00000095487.5
Wfikkn1

WAP, FS, Ig, KU, and NTR-containing protein 1

chr3_+_95622236 0.690 ENSMUST00000074353.4
Rps10-ps1
ribosomal protein S10, pseudogene 1
chr3_+_124321031 0.686 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr1_-_180813534 0.681 ENSMUST00000159789.1
ENSMUST00000081026.4
H3f3a

H3 histone, family 3A

chr9_+_104569671 0.680 ENSMUST00000057742.8
Cpne4
copine IV
chr7_+_24587543 0.676 ENSMUST00000077191.6
Ethe1
ethylmalonic encephalopathy 1
chr4_-_147936713 0.667 ENSMUST00000105712.1
ENSMUST00000019199.7
Plod1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

chr5_+_138363719 0.667 ENSMUST00000100526.2
Gm10874
predicted gene 10874
chr9_+_58134535 0.667 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr11_-_121204626 0.656 ENSMUST00000026169.6
Ogfod3
2-oxoglutarate and iron-dependent oxygenase domain containing 3
chr3_-_58525867 0.651 ENSMUST00000029385.7
Serp1
stress-associated endoplasmic reticulum protein 1
chr11_-_68927049 0.642 ENSMUST00000038932.7
Odf4
outer dense fiber of sperm tails 4
chr9_-_44344159 0.642 ENSMUST00000077353.7
Hmbs
hydroxymethylbilane synthase
chr10_+_5593718 0.633 ENSMUST00000051809.8
Myct1
myc target 1
chr11_-_98625661 0.633 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr12_+_9029982 0.630 ENSMUST00000085741.1
Ttc32
tetratricopeptide repeat domain 32
chr3_-_107931817 0.628 ENSMUST00000004137.4
Gstm7
glutathione S-transferase, mu 7
chr1_-_180813591 0.624 ENSMUST00000162118.1
ENSMUST00000159685.1
ENSMUST00000161308.1
H3f3a


H3 histone, family 3A


chr9_+_122951051 0.622 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr18_+_76930017 0.611 ENSMUST00000026487.4
Ier3ip1
immediate early response 3 interacting protein 1
chr7_-_28050028 0.608 ENSMUST00000032824.9
Psmc4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr10_+_14523062 0.605 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr15_-_35938186 0.602 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr6_-_83156393 0.602 ENSMUST00000153148.1
ENSMUST00000125894.1
Wdr54

WD repeat domain 54

chr9_+_104569754 0.590 ENSMUST00000077190.6
Cpne4
copine IV
chr9_+_115909455 0.586 ENSMUST00000119291.1
ENSMUST00000069651.6
Gadl1

glutamate decarboxylase-like 1

chr9_+_121710389 0.580 ENSMUST00000035113.9
Deb1
differentially expressed in B16F10 1
chr10_+_102158858 0.575 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr4_-_3973581 0.572 ENSMUST00000089430.4
Gm11808
predicted gene 11808
chr9_+_75441518 0.567 ENSMUST00000048937.4
Leo1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_+_83159733 0.567 ENSMUST00000113436.1
ENSMUST00000065436.3
ENSMUST00000065403.6
Daw1


dynein assembly factor with WDR repeat domains 1


chr9_-_14782964 0.560 ENSMUST00000034406.3
Ankrd49
ankyrin repeat domain 49
chr7_+_119690026 0.560 ENSMUST00000047045.8
Acsm4
acyl-CoA synthetase medium-chain family member 4
chr2_+_174285256 0.558 ENSMUST00000130940.1
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr8_+_48110156 0.557 ENSMUST00000174379.1
Dctd
dCMP deaminase
chr7_+_29238434 0.556 ENSMUST00000108237.1
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr11_-_101417615 0.552 ENSMUST00000070395.8
Aarsd1
alanyl-tRNA synthetase domain containing 1
chr7_+_143823135 0.551 ENSMUST00000128454.1
ENSMUST00000073878.5
Dhcr7

7-dehydrocholesterol reductase

chr6_+_113604749 0.537 ENSMUST00000035725.5
Brk1
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr5_+_115011111 0.536 ENSMUST00000031530.5
Sppl3
signal peptide peptidase 3
chr1_-_45503282 0.533 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chrX_+_8892376 0.527 ENSMUST00000064196.3
B630019K06Rik
RIKEN cDNA B630019K06 gene
chr9_-_22117123 0.524 ENSMUST00000013966.6
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr17_+_80290206 0.520 ENSMUST00000061703.9
Morn2
MORN repeat containing 2
chr18_+_56562443 0.518 ENSMUST00000130163.1
ENSMUST00000132628.1
Phax

phosphorylated adaptor for RNA export

chr5_+_145140362 0.518 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31



BUD31 homolog (yeast)



chr10_-_26078987 0.517 ENSMUST00000066049.6
Tmem200a
transmembrane protein 200A
chr12_+_44328882 0.511 ENSMUST00000020939.8
ENSMUST00000110748.2
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chrX_-_73921828 0.509 ENSMUST00000096316.3
ENSMUST00000114390.1
ENSMUST00000114391.3
ENSMUST00000114387.1
Naa10



N(alpha)-acetyltransferase 10, NatA catalytic subunit



chr3_-_119783262 0.506 ENSMUST00000029780.7
Ptbp2
polypyrimidine tract binding protein 2
chr4_-_42084291 0.503 ENSMUST00000177937.1
Gm21968
predicted gene, 21968
chr15_+_52712434 0.501 ENSMUST00000037115.7
Med30
mediator complex subunit 30
chr8_+_95825353 0.500 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr13_-_63398167 0.500 ENSMUST00000160735.1
Fancc
Fanconi anemia, complementation group C
chr11_+_108682602 0.499 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr2_-_25224653 0.493 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr19_-_31765027 0.491 ENSMUST00000065067.6
Prkg1
protein kinase, cGMP-dependent, type I
chr7_+_140125651 0.490 ENSMUST00000026537.5
ENSMUST00000097967.3
Paox

polyamine oxidase (exo-N4-amino)

chr5_+_31613939 0.484 ENSMUST00000031024.7
Mrpl33
mitochondrial ribosomal protein L33
chr8_+_48109949 0.484 ENSMUST00000170263.2
ENSMUST00000033966.6
Dctd

dCMP deaminase

chr14_+_55015454 0.483 ENSMUST00000022815.8
Ngdn
neuroguidin, EIF4E binding protein
chr4_-_42581621 0.482 ENSMUST00000178742.1
Gm10592
predicted gene 10592
chr4_-_83285141 0.482 ENSMUST00000150522.1
Ttc39b
tetratricopeptide repeat domain 39B
chr6_-_86684510 0.479 ENSMUST00000001186.4
ENSMUST00000113683.1
Snrnp27

small nuclear ribonucleoprotein 27 (U4/U6.U5)

chr2_-_60963192 0.478 ENSMUST00000028347.6
Rbms1
RNA binding motif, single stranded interacting protein 1
chr6_+_86628174 0.471 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr4_+_95557494 0.470 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr15_-_35938009 0.468 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr2_+_181763315 0.467 ENSMUST00000081125.4
Myt1
myelin transcription factor 1
chr2_-_174346712 0.467 ENSMUST00000168292.1
Gm20721
predicted gene, 20721

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.0 8.7 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.8 5.7 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.8 3.8 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.7 2.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.6 1.7 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.5 1.5 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.5 2.4 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.5 1.9 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.4 1.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.4 0.8 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.4 1.2 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.4 1.5 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.4 1.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3 1.0 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.3 2.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 2.3 GO:0030916 otic vesicle formation(GO:0030916) semicircular canal morphogenesis(GO:0048752)
0.3 1.3 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.3 1.2 GO:0061743 motor learning(GO:0061743)
0.3 0.9 GO:0051030 snRNA transport(GO:0051030)
0.3 0.3 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.3 1.7 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.3 0.8 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.3 1.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.2 2.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 0.7 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.2 1.9 GO:0009249 protein lipoylation(GO:0009249)
0.2 0.9 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.2 1.1 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.2 0.6 GO:0018065 protein-cofactor linkage(GO:0018065)
0.2 1.0 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 0.8 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.2 1.0 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.2 0.6 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.6 GO:0016132 brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
0.2 1.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.5 GO:1902713 regulation of interferon-gamma secretion(GO:1902713)
0.2 0.7 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 0.5 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.2 0.5 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.2 0.6 GO:0060032 notochord regression(GO:0060032)
0.2 0.6 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 0.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 0.5 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 1.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 0.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.7 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.1 0.4 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 1.1 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 1.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 1.0 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 1.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 1.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 0.9 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.5 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.4 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 2.2 GO:0043486 histone exchange(GO:0043486)
0.1 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.5 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 1.0 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.3 GO:0019401 alditol biosynthetic process(GO:0019401)
0.1 1.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.4 GO:0060414 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.0 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.5 GO:0060539 diaphragm development(GO:0060539)
0.1 0.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 1.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 1.4 GO:0006825 copper ion transport(GO:0006825)
0.1 2.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.3 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 0.5 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.4 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.1 0.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.2 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.3 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.7 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.7 GO:0000338 protein deneddylation(GO:0000338)
0.0 3.8 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 2.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.9 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.6 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.2 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.5 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.6 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 1.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.4 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:2001184 regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.9 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0003211 cardiac ventricle formation(GO:0003211)
0.0 1.0 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.4 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.5 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.1 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0098734 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.2 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 1.0 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 1.7 GO:0009566 fertilization(GO:0009566)
0.0 1.8 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.5 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.4 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.8 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.4 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.7 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.9 GO:0001942 hair follicle development(GO:0001942) skin epidermis development(GO:0098773)
0.0 0.5 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.1 GO:0007050 cell cycle arrest(GO:0007050)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.3 GO:0031262 Ndc80 complex(GO:0031262)
0.4 1.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.4 1.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4 3.5 GO:0000805 X chromosome(GO:0000805)
0.3 1.0 GO:0005584 collagen type I trimer(GO:0005584)
0.3 1.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 0.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 0.8 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.0 GO:0044305 calyx of Held(GO:0044305)
0.1 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.5 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.5 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.6 GO:0097542 ciliary tip(GO:0097542)
0.1 0.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 1.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.8 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 1.0 GO:0070852 cell body fiber(GO:0070852)
0.1 0.4 GO:0000938 GARP complex(GO:0000938)
0.1 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.0 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 2.4 GO:0097546 ciliary base(GO:0097546)
0.1 0.9 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.7 GO:0016460 myosin II complex(GO:0016460)
0.1 0.4 GO:0005638 lamin filament(GO:0005638)
0.1 2.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 1.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 3.2 GO:0070469 respiratory chain(GO:0070469)
0.0 2.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 2.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 1.8 GO:0072562 blood microparticle(GO:0072562)
0.0 0.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.6 1.9 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.6 1.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.5 1.5 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.4 1.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 2.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.3 1.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 1.4 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.3 0.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.3 1.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 0.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 1.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 0.9 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 0.6 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.2 0.6 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 0.6 GO:0009918 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.2 3.5 GO:0001848 complement binding(GO:0001848)
0.2 0.7 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.2 1.0 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 1.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 0.5 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2 0.8 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2 1.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.9 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 3.8 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 2.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.6 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.5 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.7 GO:0016531 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.1 0.3 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.3 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.1 0.4 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 2.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.7 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 1.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.3 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 3.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.8 GO:0070513 death domain binding(GO:0070513)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.7 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 1.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.9 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 2.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 1.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.7 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.0 GO:0019842 vitamin binding(GO:0019842)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 2.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 2.0 GO:0042393 histone binding(GO:0042393)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.3 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 3.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.3 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.0 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.9 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.5 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.6 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.0 PID_MYC_PATHWAY C-MYC pathway
0.0 1.1 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.0 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.2 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.7 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.8 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 3.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.4 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.2 PID_RHOA_PATHWAY RhoA signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.3 9.2 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 2.5 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 1.2 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 1.4 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.8 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.0 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.0 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.2 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 6.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.1 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.3 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.8 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.0 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.4 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 3.8 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 5.8 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.9 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.7 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 1.0 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.3 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.7 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.8 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.6 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.2 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import