Motif ID: Hoxa4

Z-value: 0.863


Transcription factors associated with Hoxa4:

Gene SymbolEntrez IDGene Name
Hoxa4 ENSMUSG00000000942.10 Hoxa4



Activity profile for motif Hoxa4.

activity profile for motif Hoxa4


Sorted Z-values histogram for motif Hoxa4

Sorted Z-values for motif Hoxa4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_80802789 3.439 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr4_+_144892813 3.319 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr2_+_71528657 2.748 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr4_+_144893077 2.685 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr18_-_31949571 2.571 ENSMUST00000064016.5
Gpr17
G protein-coupled receptor 17
chr7_-_19699008 2.271 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr4_+_144893127 2.247 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr14_-_79771305 2.166 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr4_+_119814495 2.001 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr12_+_38780284 1.995 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr12_+_38780817 1.858 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr2_-_77519565 1.833 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr5_+_17574726 1.679 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_+_70563435 1.605 ENSMUST00000123330.1
Gad1
glutamate decarboxylase 1
chr3_+_86070915 1.431 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr2_+_170731807 1.407 ENSMUST00000029075.4
Dok5
docking protein 5
chr2_-_65529275 1.292 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chr5_-_122002340 1.287 ENSMUST00000134326.1
Cux2
cut-like homeobox 2
chr14_-_30353468 1.257 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr11_+_57011945 1.251 ENSMUST00000094179.4
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr18_+_37489465 1.248 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr12_+_29528382 1.225 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr11_+_57011798 1.204 ENSMUST00000036315.9
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr11_+_29463735 1.180 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr2_+_65930117 1.160 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr19_-_57197435 1.123 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chrX_+_159840463 1.104 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr1_-_158356258 1.104 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr19_-_57197377 1.038 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chrX_+_136822781 1.036 ENSMUST00000113085.1
Plp1
proteolipid protein (myelin) 1
chr9_-_29412204 1.031 ENSMUST00000115237.1
Ntm
neurotrimin
chr3_-_146682410 1.018 ENSMUST00000124931.1
ENSMUST00000147113.1
Samd13

sterile alpha motif domain containing 13

chr2_+_90885860 1.007 ENSMUST00000111466.2
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr12_+_38781093 1.003 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr13_-_117025505 0.983 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr13_+_42680565 0.962 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr15_-_77956658 0.935 ENSMUST00000117725.1
ENSMUST00000016696.6
Foxred2

FAD-dependent oxidoreductase domain containing 2

chr19_-_57197496 0.923 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr5_+_137030275 0.919 ENSMUST00000041543.8
Vgf
VGF nerve growth factor inducible
chr16_-_76373827 0.900 ENSMUST00000121927.1
Nrip1
nuclear receptor interacting protein 1
chr9_-_49798905 0.883 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr18_-_37178493 0.880 ENSMUST00000181887.1
ENSMUST00000180516.1
Gm10544

predicted gene 10544

chr19_-_28967794 0.879 ENSMUST00000162110.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr6_+_58833689 0.878 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr17_-_26886175 0.870 ENSMUST00000108741.2
Gm17382
predicted gene, 17382
chr9_-_49798729 0.869 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr3_+_5218516 0.861 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr2_-_6884940 0.859 ENSMUST00000183091.1
ENSMUST00000182851.1
Celf2

CUGBP, Elav-like family member 2

chr18_+_37435602 0.843 ENSMUST00000055495.5
Pcdhb12
protocadherin beta 12
chr2_-_5676046 0.841 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr19_-_57197556 0.840 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr15_+_18818895 0.840 ENSMUST00000166873.2
Cdh10
cadherin 10
chr1_-_180193475 0.839 ENSMUST00000160482.1
ENSMUST00000170472.1
Adck3

aarF domain containing kinase 3

chr15_-_99820072 0.838 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chrX_+_136822671 0.833 ENSMUST00000033800.6
Plp1
proteolipid protein (myelin) 1
chr3_+_5218589 0.826 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr3_+_5218546 0.812 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr1_-_130729249 0.799 ENSMUST00000171479.1
Pfkfb2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr1_+_165788681 0.790 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr18_+_37355271 0.777 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr12_+_109546333 0.768 ENSMUST00000166636.2
Meg3
maternally expressed 3
chrX_+_56454871 0.762 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr5_-_111761697 0.757 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
E130006D01Rik


RIKEN cDNA E130006D01 gene


chr3_-_122619442 0.748 ENSMUST00000162947.1
Fnbp1l
formin binding protein 1-like
chr18_+_76059458 0.744 ENSMUST00000167921.1
Zbtb7c
zinc finger and BTB domain containing 7C
chr17_+_39846958 0.743 ENSMUST00000182010.1
Gm26924
predicted gene, 26924
chr10_+_39612934 0.732 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr1_+_165788746 0.730 ENSMUST00000161559.2
Cd247
CD247 antigen
chr12_+_109546409 0.729 ENSMUST00000143847.1
Meg3
maternally expressed 3
chr10_+_69534208 0.725 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3





ankyrin 3, epithelial





chr7_+_30121915 0.694 ENSMUST00000098596.3
ENSMUST00000153792.1
Zfp382

zinc finger protein 382

chr2_+_4400958 0.684 ENSMUST00000075767.7
Frmd4a
FERM domain containing 4A
chr9_-_42399915 0.674 ENSMUST00000042190.7
Tecta
tectorin alpha
chr17_+_45734506 0.674 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr9_-_55919605 0.669 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr12_+_65075582 0.659 ENSMUST00000058889.4
Fancm
Fanconi anemia, complementation group M
chr17_-_43667015 0.651 ENSMUST00000024705.4
Slc25a27
solute carrier family 25, member 27
chr10_-_128525859 0.647 ENSMUST00000026427.6
Esyt1
extended synaptotagmin-like protein 1
chr8_-_84937347 0.642 ENSMUST00000109741.2
ENSMUST00000119820.1
Mast1

microtubule associated serine/threonine kinase 1

chr2_-_6884975 0.637 ENSMUST00000114924.3
ENSMUST00000170438.1
ENSMUST00000114934.4
Celf2


CUGBP, Elav-like family member 2


chr3_+_88965812 0.591 ENSMUST00000090933.4
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr1_+_180101144 0.591 ENSMUST00000133890.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr7_+_34251038 0.581 ENSMUST00000105172.1
Gm6096
predicted gene 6096
chr6_+_8949670 0.536 ENSMUST00000060369.3
Nxph1
neurexophilin 1
chr5_+_76809964 0.535 ENSMUST00000120818.1
C530008M17Rik
RIKEN cDNA C530008M17 gene
chr16_-_64786321 0.534 ENSMUST00000052588.4
Zfp654
zinc finger protein 654
chr19_+_11965817 0.524 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr1_-_165934900 0.512 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr1_+_19103022 0.507 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr7_+_64185459 0.497 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
Trpm1





transient receptor potential cation channel, subfamily M, member 1





chr1_-_152766281 0.491 ENSMUST00000111859.1
ENSMUST00000148865.1
Rgl1

ral guanine nucleotide dissociation stimulator,-like 1

chr15_+_62037986 0.487 ENSMUST00000182956.1
ENSMUST00000182075.1
ENSMUST00000180432.2
ENSMUST00000181416.2
ENSMUST00000181657.2
Pvt1




plasmacytoma variant translocation 1




chr15_+_55307743 0.475 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr13_-_107890059 0.473 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr15_-_37458523 0.472 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr5_+_64812336 0.469 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr18_+_37447641 0.467 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr12_-_84361802 0.465 ENSMUST00000021659.1
ENSMUST00000065536.2
Fam161b

family with sequence similarity 161, member B

chr7_+_79273201 0.450 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr5_-_146220901 0.449 ENSMUST00000169407.2
ENSMUST00000161331.1
ENSMUST00000159074.2
ENSMUST00000067837.3
Rnf6



ring finger protein (C3H2C3 type) 6



chr6_-_77979515 0.439 ENSMUST00000159626.1
ENSMUST00000075340.5
ENSMUST00000162273.1
Ctnna2


catenin (cadherin associated protein), alpha 2


chr10_+_53337686 0.438 ENSMUST00000046221.6
ENSMUST00000163319.1
Pln

phospholamban

chr15_-_37459327 0.429 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr8_+_4238733 0.425 ENSMUST00000110998.2
ENSMUST00000062686.4
Map2k7

mitogen-activated protein kinase kinase 7

chr12_+_38783455 0.423 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr9_+_72274966 0.418 ENSMUST00000183410.1
Zfp280d
zinc finger protein 280D
chr18_+_37341702 0.417 ENSMUST00000053037.3
Pcdhb7
protocadherin beta 7
chr17_-_71459300 0.416 ENSMUST00000183937.1
Gm4707
predicted gene 4707
chr3_+_68572245 0.406 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr3_-_146781351 0.401 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr8_+_4238815 0.392 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr10_-_70655934 0.379 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chr10_-_127121125 0.379 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chr12_+_38783503 0.375 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr6_+_86527312 0.374 ENSMUST00000181928.1
1600020E01Rik
RIKEN cDNA 1600020E01 gene
chr4_+_138775735 0.365 ENSMUST00000030528.2
Pla2g2d
phospholipase A2, group IID
chr13_+_58807884 0.363 ENSMUST00000079828.5
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr3_+_95164306 0.356 ENSMUST00000107217.1
ENSMUST00000168321.1
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr1_-_67038824 0.339 ENSMUST00000119559.1
ENSMUST00000149996.1
ENSMUST00000027149.5
ENSMUST00000113979.3
Lancl1



LanC (bacterial lantibiotic synthetase component C)-like 1



chr18_+_23752333 0.338 ENSMUST00000170802.1
ENSMUST00000155708.1
ENSMUST00000118826.2
Mapre2


microtubule-associated protein, RP/EB family, member 2


chr18_+_37819543 0.331 ENSMUST00000055935.5
Pcdhga9
protocadherin gamma subfamily A, 9
chr16_+_10812915 0.318 ENSMUST00000115822.1
Gm11172
predicted gene 11172
chr16_+_4639941 0.295 ENSMUST00000038770.3
Vasn
vasorin
chr14_-_108914237 0.294 ENSMUST00000100322.2
Slitrk1
SLIT and NTRK-like family, member 1
chr18_-_79109391 0.291 ENSMUST00000025430.8
ENSMUST00000161465.2
Setbp1

SET binding protein 1

chr11_-_121673103 0.288 ENSMUST00000067399.7
ENSMUST00000062654.7
B3gntl1

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1

chr7_+_112742025 0.276 ENSMUST00000164363.1
Tead1
TEA domain family member 1
chr12_-_27160311 0.268 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr13_+_23555023 0.267 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr12_+_84362029 0.266 ENSMUST00000110278.1
ENSMUST00000145522.1
Coq6

coenzyme Q6 homolog (yeast)

chr19_+_8840519 0.260 ENSMUST00000086058.6
Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr2_-_93849679 0.259 ENSMUST00000068513.4
ENSMUST00000041593.8
ENSMUST00000130077.1
Accs


1-aminocyclopropane-1-carboxylate synthase (non-functional)


chr11_-_30268169 0.251 ENSMUST00000006629.7
Sptbn1
spectrin beta, non-erythrocytic 1
chr1_-_152766323 0.251 ENSMUST00000111857.1
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr2_-_116065798 0.246 ENSMUST00000110907.1
ENSMUST00000110908.2
Meis2

Meis homeobox 2

chr3_+_116562965 0.244 ENSMUST00000029573.5
Lrrc39
leucine rich repeat containing 39
chr5_-_84417359 0.242 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr1_+_180111339 0.240 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr18_+_37307445 0.237 ENSMUST00000056712.2
Pcdhb4
protocadherin beta 4
chr5_-_124187150 0.237 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr14_+_65266701 0.233 ENSMUST00000169656.1
Fbxo16
F-box protein 16
chr2_+_83644435 0.231 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr5_+_30814722 0.230 ENSMUST00000114724.1
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr3_+_94837533 0.230 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr12_+_84361968 0.220 ENSMUST00000021661.6
Coq6
coenzyme Q6 homolog (yeast)
chr3_+_94837702 0.218 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
Pogz


pogo transposable element with ZNF domain


chr18_-_42579652 0.214 ENSMUST00000054738.3
Gpr151
G protein-coupled receptor 151
chr4_-_129378116 0.212 ENSMUST00000030610.2
Zbtb8a
zinc finger and BTB domain containing 8a
chr7_-_100855403 0.212 ENSMUST00000156855.1
Relt
RELT tumor necrosis factor receptor
chr6_+_124304646 0.193 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr8_-_67974567 0.190 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
Psd3


pleckstrin and Sec7 domain containing 3


chrX_-_20950597 0.187 ENSMUST00000009550.7
Elk1
ELK1, member of ETS oncogene family
chr1_+_93478964 0.180 ENSMUST00000027495.8
ENSMUST00000136182.1
ENSMUST00000131175.2
ENSMUST00000179353.1
ENSMUST00000172165.1
ENSMUST00000153826.1
ENSMUST00000129211.1
ENSMUST00000168776.1
ENSMUST00000112912.1
Sept2








septin 2








chr9_-_50555170 0.171 ENSMUST00000119103.1
Bco2
beta-carotene oxygenase 2
chr4_+_130107556 0.169 ENSMUST00000030563.5
Pef1
penta-EF hand domain containing 1
chr4_-_118179946 0.167 ENSMUST00000050288.8
ENSMUST00000106403.1
Kdm4a

lysine (K)-specific demethylase 4A

chr11_-_30986326 0.166 ENSMUST00000020553.4
ENSMUST00000101394.4
Chac2

ChaC, cation transport regulator 2

chr4_-_118180043 0.165 ENSMUST00000106406.2
Kdm4a
lysine (K)-specific demethylase 4A
chr17_+_24850654 0.162 ENSMUST00000130989.1
ENSMUST00000024974.9
Hagh

hydroxyacyl glutathione hydrolase

chr12_+_84361636 0.155 ENSMUST00000110276.1
Coq6
coenzyme Q6 homolog (yeast)
chr6_-_56901870 0.153 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr6_+_29467718 0.150 ENSMUST00000004396.6
Atp6v1f
ATPase, H+ transporting, lysosomal V1 subunit F
chr2_-_116065047 0.148 ENSMUST00000028639.6
ENSMUST00000102538.4
Meis2

Meis homeobox 2

chr17_+_24850515 0.147 ENSMUST00000154363.1
ENSMUST00000169200.1
Hagh

hydroxyacyl glutathione hydrolase

chr8_+_46986913 0.144 ENSMUST00000039840.7
ENSMUST00000119686.1
Enpp6

ectonucleotide pyrophosphatase/phosphodiesterase 6

chr12_+_84996309 0.140 ENSMUST00000168977.1
ENSMUST00000021670.8
Ylpm1

YLP motif containing 1

chr10_+_87859062 0.134 ENSMUST00000095360.4
Igf1
insulin-like growth factor 1
chr9_+_75775355 0.127 ENSMUST00000012281.7
Bmp5
bone morphogenetic protein 5
chr9_-_110624361 0.121 ENSMUST00000035069.9
Nradd
neurotrophin receptor associated death domain
chr8_+_47713266 0.112 ENSMUST00000180928.1
E030037K01Rik
RIKEN cDNA E030037K01 gene
chr6_+_124916863 0.109 ENSMUST00000069553.2
A230083G16Rik
RIKEN cDNA A230083G16 gene
chrX_+_140367494 0.093 ENSMUST00000141660.1
Frmpd3
FERM and PDZ domain containing 3
chr13_+_38204928 0.092 ENSMUST00000091641.5
ENSMUST00000178564.1
Snrnp48

small nuclear ribonucleoprotein 48 (U11/U12)

chr1_+_165301863 0.081 ENSMUST00000178700.1
Gpr161
G protein-coupled receptor 161
chr16_-_22857514 0.079 ENSMUST00000004576.6
Tbccd1
TBCC domain containing 1
chr13_+_63014934 0.070 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr15_-_56694525 0.052 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr10_+_127420334 0.042 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr4_-_62519885 0.037 ENSMUST00000107444.1
ENSMUST00000030090.3
Alad

aminolevulinate, delta-, dehydratase

chr6_+_63255971 0.034 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr1_-_74601345 0.030 ENSMUST00000136078.1
ENSMUST00000132081.1
ENSMUST00000113721.1
ENSMUST00000027357.5
Rnf25



ring finger protein 25



chr9_+_44398176 0.029 ENSMUST00000165839.1
Slc37a4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr12_-_80760541 0.023 ENSMUST00000073251.6
Ccdc177
coiled-coil domain containing 177
chr2_+_109917639 0.019 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr1_+_143739573 0.013 ENSMUST00000111957.3
ENSMUST00000145571.1
Glrx2

glutaredoxin 2 (thioltransferase)

chr9_-_65885024 0.012 ENSMUST00000122410.1
ENSMUST00000117083.1
Trip4

thyroid hormone receptor interactor 4

chr19_-_38224096 0.011 ENSMUST00000067167.5
Fra10ac1
FRA10AC1 homolog (human)
chrX_+_48623737 0.009 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr6_-_102464667 0.008 ENSMUST00000032159.6
Cntn3
contactin 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.8 2.3 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.7 8.0 GO:0042572 retinol metabolic process(GO:0042572)
0.6 1.8 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.5 6.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 2.6 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.3 1.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 0.9 GO:0001543 ovarian follicle rupture(GO:0001543)
0.3 1.7 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 1.3 GO:0046684 response to pyrethroid(GO:0046684)
0.2 1.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 1.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.7 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.6 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.1 1.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 5.7 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 0.5 GO:0030901 midbrain development(GO:0030901)
0.1 1.4 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.7 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 0.8 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.5 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.9 GO:0043084 penile erection(GO:0043084)
0.1 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.7 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.7 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 1.3 GO:0007614 short-term memory(GO:0007614)
0.1 4.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 1.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 3.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.4 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.5 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.5 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.4 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0021502 neural fold elevation formation(GO:0021502)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.6 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.2 GO:0042574 isoprenoid catabolic process(GO:0008300) retinal metabolic process(GO:0042574)
0.0 0.4 GO:0001553 luteinization(GO:0001553)
0.0 0.4 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)
0.0 0.7 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.1 GO:1900623 positive regulation of keratinocyte proliferation(GO:0010838) monocyte aggregation(GO:0070487) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.7 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.5 GO:2001222 regulation of neuron migration(GO:2001222)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.4 2.5 GO:0044308 axonal spine(GO:0044308)
0.4 1.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 3.4 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.4 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 2.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 5.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0051286 cell tip(GO:0051286)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.9 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 8.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.8 5.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.8 2.3 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 1.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 0.8 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 1.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 1.7 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.2 GO:0050897 cobalt ion binding(GO:0050897)
0.1 1.8 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.9 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 1.8 GO:0002039 p53 binding(GO:0002039)
0.0 1.5 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 2.4 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 4.5 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.7 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 7.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.4 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 2.3 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 1.4 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.5 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.9 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.4 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.7 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.4 PID_FGF_PATHWAY FGF signaling pathway
0.0 1.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID_SHP2_PATHWAY SHP2 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 1.5 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 5.9 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 2.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.9 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.6 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.9 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 1.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.8 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.7 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 1.0 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation