Motif ID: Hoxa7_Hoxc8
Z-value: 0.429
Transcription factors associated with Hoxa7_Hoxc8:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxa7 | ENSMUSG00000038236.6 | Hoxa7 |
Hoxc8 | ENSMUSG00000001657.6 | Hoxc8 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.5 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.3 | 1.2 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.2 | 2.9 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.1 | 0.6 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
0.1 | 0.4 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
0.1 | 0.5 | GO:0019532 | oxalate transport(GO:0019532) |
0.1 | 0.2 | GO:2000564 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.1 | 0.4 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.0 | 0.3 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
0.0 | 2.0 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 0.5 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.0 | 0.2 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.0 | 0.2 | GO:0030242 | pexophagy(GO:0030242) |
0.0 | 0.2 | GO:0098707 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
0.0 | 0.1 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
0.0 | 0.1 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.0 | 0.1 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
0.0 | 0.1 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.0 | 0.1 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
0.0 | 0.1 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
0.0 | 0.1 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.1 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
0.0 | 0.1 | GO:0043407 | negative regulation of MAP kinase activity(GO:0043407) |
0.0 | 0.4 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.0 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 0.4 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.0 | 0.2 | GO:0097433 | dense body(GO:0097433) |
0.0 | 1.1 | GO:0031672 | A band(GO:0031672) |
0.0 | 0.5 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 0.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 0.5 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.0 | 0.1 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.0 | 2.5 | GO:0043197 | dendritic spine(GO:0043197) |
0.0 | 0.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 2.5 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.1 | 0.4 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.0 | 0.5 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 0.3 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 0.4 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 0.2 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 0.2 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.0 | 0.1 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.0 | 0.1 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.0 | 0.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.0 | 0.6 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.0 | 0.2 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.0 | 1.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.4 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.1 | GO:0051378 | primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378) |
0.0 | 0.1 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.0 | 0.1 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
0.0 | 0.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.5 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.4 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 0.1 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 3.9 | GO:0008017 | microtubule binding(GO:0008017) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.9 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 1.2 | PID_ARF6_PATHWAY | Arf6 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.4 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.0 | 1.8 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.0 | 0.4 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 0.4 | REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS | Genes involved in Prolonged ERK activation events |
0.0 | 2.7 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
0.0 | 0.5 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.0 | 0.5 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |