Motif ID: Hoxb13

Z-value: 0.848


Transcription factors associated with Hoxb13:

Gene SymbolEntrez IDGene Name
Hoxb13 ENSMUSG00000049604.3 Hoxb13



Activity profile for motif Hoxb13.

activity profile for motif Hoxb13


Sorted Z-values histogram for motif Hoxb13

Sorted Z-values for motif Hoxb13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb13

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_38783503 1.289 ENSMUST00000159334.1
Etv1
ets variant gene 1
chrY_-_1286563 1.249 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr3_+_106034661 0.917 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr15_+_85510812 0.913 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr16_-_89508313 0.801 ENSMUST00000056118.2
Krtap7-1
keratin associated protein 7-1
chr3_+_66219909 0.764 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr16_+_91269759 0.650 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr4_-_92191749 0.618 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr9_+_65890237 0.610 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chrY_+_897782 0.600 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr7_+_97400003 0.574 ENSMUST00000032882.8
Ndufc2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr3_-_96197580 0.499 ENSMUST00000016087.3
Bola1
bolA-like 1 (E. coli)
chrX_+_99042581 0.489 ENSMUST00000036606.7
Stard8
START domain containing 8
chr7_-_139582790 0.481 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr13_+_65512678 0.477 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chr12_+_38783455 0.458 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr1_-_162866502 0.454 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr13_+_104229366 0.446 ENSMUST00000022227.6
Cenpk
centromere protein K
chr7_+_43690418 0.430 ENSMUST00000056329.6
Klk14
kallikrein related-peptidase 14
chr3_-_150073620 0.425 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 243 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.9 GO:0009404 toxin metabolic process(GO:0009404)
0.2 0.8 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.7 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.6 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.1 0.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.4 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.4 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 0.4 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 0.4 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.4 GO:0007320 insemination(GO:0007320)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 93 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.9 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.5 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.5 GO:0000243 commitment complex(GO:0000243)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0070187 telosome(GO:0070187)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 155 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.8 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.8 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.2 0.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 0.4 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.4 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0000150 recombinase activity(GO:0000150)

Gene overrepresentation in C2:CP category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.4 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.1 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.1 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 1.6 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 1.0 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.6 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA