Motif ID: Hoxb7

Z-value: 4.531


Transcription factors associated with Hoxb7:

Gene SymbolEntrez IDGene Name
Hoxb7 ENSMUSG00000038721.8 Hoxb7



Activity profile for motif Hoxb7.

activity profile for motif Hoxb7


Sorted Z-values histogram for motif Hoxb7

Sorted Z-values for motif Hoxb7



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_83504032 35.830 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr4_+_102589687 27.593 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr2_+_71528657 23.096 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr16_+_42907563 22.493 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr5_+_117841839 20.965 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr1_+_19103022 20.657 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr15_+_21111452 19.140 ENSMUST00000075132.6
Cdh12
cadherin 12
chr1_-_56969827 19.072 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_56969864 18.618 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr6_-_136171722 18.409 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr16_+_43247278 17.716 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr17_-_81649607 17.373 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr19_-_28911879 16.445 ENSMUST00000179171.1
AC163993.1
AC163993.1
chr6_-_13839916 16.433 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr2_+_65930117 15.453 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr9_-_40346290 15.263 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr8_+_54954728 15.240 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr2_-_7396192 15.121 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr7_+_91090697 15.034 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr12_+_29528382 14.980 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr16_+_7069825 14.977 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr13_+_42681513 14.949 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr19_+_26750939 14.757 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_+_91090728 14.694 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr13_+_42680565 14.694 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr15_-_66812593 14.136 ENSMUST00000100572.3
Sla
src-like adaptor
chr19_+_26605106 14.089 ENSMUST00000025862.7
ENSMUST00000176030.1
Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr11_-_30198232 13.971 ENSMUST00000102838.3
Sptbn1
spectrin beta, non-erythrocytic 1
chr1_+_159737510 13.804 ENSMUST00000111669.3
Tnr
tenascin R
chr11_-_37235882 13.634 ENSMUST00000102801.1
Tenm2
teneurin transmembrane protein 2
chr2_-_36104060 13.548 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr17_+_3397189 13.544 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr19_+_26749726 13.510 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_7395879 13.506 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr4_+_13751297 13.191 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_+_92597104 12.905 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr3_+_55461758 12.745 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr3_+_68572245 12.338 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr9_-_29963112 12.136 ENSMUST00000075069.4
Ntm
neurotrimin
chr2_+_65620829 11.817 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr1_+_66321708 11.668 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr5_+_19907774 11.582 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_45112890 11.440 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr2_-_7081207 11.368 ENSMUST00000114923.2
ENSMUST00000182706.1
Celf2

CUGBP, Elav-like family member 2

chrX_-_143933089 11.078 ENSMUST00000087313.3
Dcx
doublecortin
chr9_-_112187766 10.927 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr13_+_16014457 10.907 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr13_-_84064772 10.817 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr15_+_18818895 10.809 ENSMUST00000166873.2
Cdh10
cadherin 10
chr2_-_6884940 10.803 ENSMUST00000183091.1
ENSMUST00000182851.1
Celf2

CUGBP, Elav-like family member 2

chr5_+_66968559 10.665 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr1_+_179961110 10.621 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr2_+_37516618 10.520 ENSMUST00000065441.6
Gpr21
G protein-coupled receptor 21
chr9_-_112187898 10.448 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr1_+_177445660 10.365 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr3_+_18054258 10.299 ENSMUST00000026120.6
Bhlhe22
basic helix-loop-helix family, member e22
chr10_-_109009055 10.194 ENSMUST00000156979.1
Syt1
synaptotagmin I
chr1_+_34005872 10.170 ENSMUST00000182296.1
Dst
dystonin
chr4_-_64046925 10.017 ENSMUST00000107377.3
Tnc
tenascin C
chr1_-_56971762 9.981 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chr5_+_107497762 9.925 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr1_-_56978534 9.671 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr1_+_81077274 9.640 ENSMUST00000068275.5
ENSMUST00000113494.2
Nyap2

neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2

chr6_-_13838432 9.521 ENSMUST00000115492.1
Gpr85
G protein-coupled receptor 85
chr14_+_101840602 9.497 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr13_+_42866247 9.452 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr17_+_70561739 9.338 ENSMUST00000097288.2
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr13_+_76579670 9.306 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr3_-_26133734 9.292 ENSMUST00000108308.3
ENSMUST00000075054.4
Nlgn1

neuroligin 1

chr6_+_96113146 9.284 ENSMUST00000122120.1
Fam19a1
family with sequence similarity 19, member A1
chr3_-_146770218 9.114 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr17_+_70522083 9.011 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chrX_-_43167817 8.992 ENSMUST00000115058.1
ENSMUST00000115059.1
Tenm1

teneurin transmembrane protein 1

chr19_+_26748268 8.948 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr16_-_23988852 8.921 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr13_+_109926832 8.911 ENSMUST00000117420.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr6_-_118780324 8.804 ENSMUST00000112793.3
ENSMUST00000075591.6
ENSMUST00000078320.7
ENSMUST00000112790.2
Cacna1c



calcium channel, voltage-dependent, L type, alpha 1C subunit



chr6_+_80018877 8.759 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr9_-_49798905 8.725 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr14_+_101840501 8.706 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr2_+_68104671 8.648 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr1_+_167598450 8.591 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr11_-_98053415 8.590 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr15_-_8710409 8.538 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_+_66322102 8.520 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr3_-_146770603 8.397 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr1_+_177444653 8.368 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr1_-_165934900 8.358 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr2_-_65567505 8.301 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr15_-_66831625 8.299 ENSMUST00000164163.1
Sla
src-like adaptor
chr2_-_7081256 8.296 ENSMUST00000183209.1
Celf2
CUGBP, Elav-like family member 2
chr5_+_66968961 8.296 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr8_-_84773381 8.221 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr5_+_107497718 8.221 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr4_+_119814495 7.986 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr19_-_59170978 7.981 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr2_+_4300462 7.843 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr10_+_69534208 7.830 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3





ankyrin 3, epithelial





chr2_-_6721890 7.821 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr14_-_36935560 7.795 ENSMUST00000183038.1
Ccser2
coiled-coil serine rich 2
chr15_+_92161343 7.766 ENSMUST00000068378.5
Cntn1
contactin 1
chr6_-_97459279 7.751 ENSMUST00000113359.1
Frmd4b
FERM domain containing 4B
chr13_-_101692624 7.728 ENSMUST00000035532.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr9_+_37367354 7.700 ENSMUST00000051839.7
Hepacam
hepatocyte cell adhesion molecule
chr5_+_89027959 7.631 ENSMUST00000130041.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr5_+_75152274 7.619 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr3_+_26331150 7.612 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr15_+_83791939 7.598 ENSMUST00000172115.1
ENSMUST00000172398.1
Mpped1

metallophosphoesterase domain containing 1

chr11_+_31872100 7.589 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr18_+_69593361 7.585 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr6_+_80019008 7.580 ENSMUST00000126399.1
ENSMUST00000136421.1
Lrrtm4

leucine rich repeat transmembrane neuronal 4

chrX_+_112615301 7.499 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr14_-_124677089 7.487 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr11_-_76509419 7.417 ENSMUST00000094012.4
Abr
active BCR-related gene
chr10_+_90576252 7.339 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr10_+_106470281 7.269 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr4_+_102421518 7.247 ENSMUST00000106904.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr1_-_69108039 7.226 ENSMUST00000121473.1
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr1_-_158356258 7.225 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr13_+_83573577 7.172 ENSMUST00000185052.1
Mef2c
myocyte enhancer factor 2C
chr17_-_90088343 7.158 ENSMUST00000173917.1
Nrxn1
neurexin I
chr8_-_54718664 7.148 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chr4_+_48049080 7.124 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr4_-_116405986 7.038 ENSMUST00000123072.1
ENSMUST00000144281.1
Mast2

microtubule associated serine/threonine kinase 2

chr8_-_109251698 7.032 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr3_+_13946368 6.940 ENSMUST00000171075.1
ENSMUST00000108372.2
Ralyl

RALY RNA binding protein-like

chr10_+_69787431 6.924 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr18_+_36952621 6.859 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr14_-_30353468 6.859 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr4_+_108719649 6.858 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr17_+_70522149 6.803 ENSMUST00000140728.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr16_+_43503607 6.789 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr18_-_22850738 6.772 ENSMUST00000092015.4
ENSMUST00000069215.6
Nol4

nucleolar protein 4

chr1_-_155417394 6.717 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr7_-_120202104 6.706 ENSMUST00000033198.5
Crym
crystallin, mu
chr9_-_49798729 6.704 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr10_-_109010955 6.701 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr19_-_57239310 6.693 ENSMUST00000111559.1
Ablim1
actin-binding LIM protein 1
chr2_-_65567465 6.691 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr16_-_97170707 6.676 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr1_+_81077204 6.644 ENSMUST00000123720.1
Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr8_+_66386292 6.637 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr14_-_36919314 6.620 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr18_+_23415400 6.524 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr2_-_77519565 6.522 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr9_+_32116040 6.509 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr4_+_101507947 6.487 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr3_-_80802789 6.461 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr11_-_81968415 6.423 ENSMUST00000066197.6
Asic2
acid-sensing (proton-gated) ion channel 2
chr2_-_6722187 6.394 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr11_+_29463735 6.370 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr14_-_93888732 6.366 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr1_-_38821215 6.343 ENSMUST00000039612.4
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chrX_-_143933204 6.260 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr8_+_65967157 6.223 ENSMUST00000072482.6
March1
membrane-associated ring finger (C3HC4) 1
chrX_+_159708593 6.184 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr2_-_7395968 6.183 ENSMUST00000002176.6
Celf2
CUGBP, Elav-like family member 2
chr5_+_13398688 6.172 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_85741389 6.157 ENSMUST00000094148.4
Fam160a1
family with sequence similarity 160, member A1
chr10_+_69706326 6.151 ENSMUST00000182992.1
Ank3
ankyrin 3, epithelial
chr13_-_105054895 6.138 ENSMUST00000063551.5
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr5_+_66968416 6.127 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr3_-_152982240 6.121 ENSMUST00000044278.5
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr5_+_19907502 6.065 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_-_88033328 6.062 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr13_-_97747399 5.996 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr8_-_8639363 5.983 ENSMUST00000152698.1
Efnb2
ephrin B2
chr3_+_28263205 5.977 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr1_+_66386968 5.900 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr10_-_110000219 5.888 ENSMUST00000032719.7
Nav3
neuron navigator 3
chr1_-_132707304 5.858 ENSMUST00000043189.7
Nfasc
neurofascin
chr9_+_61372359 5.855 ENSMUST00000178113.1
ENSMUST00000159386.1
Tle3

transducin-like enhancer of split 3, homolog of Drosophila E(spl)

chr2_-_132111440 5.847 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr2_-_104257400 5.828 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr10_+_42860776 5.763 ENSMUST00000105494.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chrX_+_112604274 5.760 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr4_-_14621805 5.674 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr9_-_75597643 5.613 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr18_-_35215008 5.583 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr19_+_38264761 5.491 ENSMUST00000087252.5
Lgi1
leucine-rich repeat LGI family, member 1
chr10_-_109764840 5.486 ENSMUST00000163071.1
Nav3
neuron navigator 3
chr1_-_134955908 5.483 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr2_-_5676046 5.474 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr4_+_144892813 5.454 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr3_+_5218516 5.446 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr1_+_34121250 5.434 ENSMUST00000183006.1
Dst
dystonin
chr19_-_37176055 5.432 ENSMUST00000142973.1
ENSMUST00000154376.1
Cpeb3

cytoplasmic polyadenylation element binding protein 3

chr15_-_77153772 5.405 ENSMUST00000166610.1
ENSMUST00000111581.2
Rbfox2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr6_-_28831747 5.388 ENSMUST00000062304.5
Lrrc4
leucine rich repeat containing 4
chr1_-_126830632 5.369 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr2_-_64975762 5.367 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr18_+_37496997 5.347 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr4_-_76344227 5.332 ENSMUST00000050757.9
Ptprd
protein tyrosine phosphatase, receptor type, D
chr5_-_23616528 5.319 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr8_-_41016749 5.285 ENSMUST00000117735.1
Mtus1
mitochondrial tumor suppressor 1
chr14_-_102982630 5.267 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr13_+_16011851 5.258 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr3_+_118433797 5.252 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
Gm26871



predicted gene, 26871



chr10_-_68278713 5.231 ENSMUST00000020106.7
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr18_-_23041641 5.224 ENSMUST00000097651.3
Nol4
nucleolar protein 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
14.3 43.0 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
10.1 30.3 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
8.6 25.8 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
5.8 17.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
5.7 51.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
5.5 21.9 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
5.3 31.8 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
5.1 15.4 GO:0001928 regulation of exocyst assembly(GO:0001928)
4.8 62.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
4.0 19.9 GO:0046684 response to pyrethroid(GO:0046684)
3.6 40.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.5 17.3 GO:0042701 progesterone secretion(GO:0042701)
3.4 13.5 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
3.3 26.5 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
3.2 16.0 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
3.2 12.8 GO:0043490 malate-aspartate shuttle(GO:0043490)
2.9 26.5 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
2.6 7.9 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
2.5 35.6 GO:0045161 neuronal ion channel clustering(GO:0045161)
2.5 7.6 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
2.5 10.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
2.5 12.4 GO:0007256 activation of JNKK activity(GO:0007256)
2.4 17.0 GO:0005513 detection of calcium ion(GO:0005513)
2.4 4.8 GO:0010669 epithelial structure maintenance(GO:0010669)
2.4 16.8 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
2.4 2.4 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
2.4 23.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
2.3 28.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
2.2 6.7 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
2.2 15.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
2.2 8.8 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
2.2 28.0 GO:0070842 aggresome assembly(GO:0070842)
2.1 6.4 GO:0050915 sensory perception of sour taste(GO:0050915)
2.1 34.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
2.1 8.5 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
2.1 4.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
2.1 86.2 GO:0006376 mRNA splice site selection(GO:0006376)
2.1 8.2 GO:2000795 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
2.0 12.3 GO:0072318 clathrin coat disassembly(GO:0072318)
2.0 8.2 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
2.0 17.9 GO:0071420 cellular response to histamine(GO:0071420)
1.9 15.4 GO:0086018 SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070)
1.9 5.6 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
1.8 5.4 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
1.7 10.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
1.6 13.2 GO:0097264 self proteolysis(GO:0097264)
1.6 3.3 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
1.5 9.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
1.5 4.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
1.5 7.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
1.5 7.3 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.4 58.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.4 4.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.4 23.0 GO:0097090 presynaptic membrane organization(GO:0097090)
1.3 20.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.3 4.0 GO:0071313 cellular response to caffeine(GO:0071313)
1.3 3.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.3 3.9 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
1.3 9.0 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
1.3 6.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.3 6.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
1.3 2.5 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
1.3 5.0 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
1.2 3.7 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
1.2 20.3 GO:0015701 bicarbonate transport(GO:0015701)
1.2 7.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.2 9.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
1.1 14.5 GO:0001553 luteinization(GO:0001553)
1.1 8.8 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
1.1 5.5 GO:0035063 nuclear speck organization(GO:0035063)
1.1 3.3 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
1.1 1.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
1.1 5.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.1 8.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.0 8.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.0 3.1 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
1.0 3.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
1.0 11.1 GO:0042118 endothelial cell activation(GO:0042118)
1.0 15.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
1.0 2.0 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
1.0 2.0 GO:0071872 response to epinephrine(GO:0071871) cellular response to epinephrine stimulus(GO:0071872)
1.0 14.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
1.0 3.9 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.9 5.5 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.9 3.7 GO:0060178 regulation of exocyst localization(GO:0060178)
0.9 37.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.9 4.4 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.9 6.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.9 18.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.9 10.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.8 2.5 GO:0007403 glial cell fate determination(GO:0007403)
0.8 4.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.8 2.5 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.8 4.1 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.8 2.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.8 6.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.8 5.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.8 21.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.8 5.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.8 4.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.8 2.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.8 3.9 GO:0071361 cellular response to ethanol(GO:0071361)
0.8 2.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.8 12.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.8 2.3 GO:0007525 somatic muscle development(GO:0007525)
0.7 6.0 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.7 10.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.7 5.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.7 2.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.7 7.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.7 2.2 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.7 2.9 GO:0072362 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.7 3.6 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.7 2.1 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) noradrenergic neuron differentiation(GO:0003357)
0.7 4.9 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.7 2.1 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.7 2.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.7 3.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.7 2.0 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.7 16.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.7 2.7 GO:2000821 regulation of grooming behavior(GO:2000821)
0.7 3.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.6 3.9 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.6 1.9 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.6 1.8 GO:0001543 ovarian follicle rupture(GO:0001543)
0.6 2.4 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.6 3.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.6 2.4 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.6 1.8 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.6 2.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.6 3.0 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.6 1.2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.6 8.8 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.6 2.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.6 1.7 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.6 4.0 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.6 2.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.6 1.7 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.6 12.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.6 2.2 GO:0090472 dibasic protein processing(GO:0090472)
0.6 5.0 GO:0060613 fat pad development(GO:0060613)
0.5 4.4 GO:0097475 motor neuron migration(GO:0097475)
0.5 2.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.5 1.6 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.5 1.6 GO:2000016 regulation of determination of dorsal identity(GO:2000015) negative regulation of determination of dorsal identity(GO:2000016)
0.5 2.6 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.5 15.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.5 3.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.5 1.5 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.5 23.7 GO:0034605 cellular response to heat(GO:0034605)
0.5 10.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.5 3.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.5 3.5 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.5 2.0 GO:0021984 adenohypophysis development(GO:0021984)
0.5 3.5 GO:0007296 vitellogenesis(GO:0007296)
0.5 4.9 GO:0042572 retinol metabolic process(GO:0042572)
0.5 1.4 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.5 2.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.5 3.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.5 2.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.5 2.3 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.5 2.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.5 5.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.5 1.4 GO:0002159 desmosome assembly(GO:0002159) response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.4 1.8 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.4 2.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.4 1.8 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.4 9.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.4 6.6 GO:0006007 glucose catabolic process(GO:0006007)
0.4 0.9 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) positive regulation of neuromuscular junction development(GO:1904398)
0.4 0.9 GO:0061550 cranial ganglion development(GO:0061550)
0.4 1.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 16.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.4 0.8 GO:0048859 formation of anatomical boundary(GO:0048859)
0.4 15.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.4 1.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.4 1.7 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.4 3.7 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.4 0.8 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.4 2.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.4 23.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.4 10.7 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.4 0.8 GO:1901654 response to ketone(GO:1901654) cellular response to ketone(GO:1901655)
0.4 0.8 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.4 0.8 GO:0060431 primary lung bud formation(GO:0060431)
0.4 6.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4 4.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.4 0.7 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.4 2.6 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.4 9.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.4 5.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.4 1.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.4 60.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.4 1.4 GO:0060353 regulation of cell adhesion molecule production(GO:0060353)
0.4 0.7 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.4 4.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.3 5.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 5.5 GO:0030325 adrenal gland development(GO:0030325)
0.3 3.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.3 1.0 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.3 1.0 GO:0035482 gastric motility(GO:0035482) gastric emptying(GO:0035483) negative regulation of gastric acid secretion(GO:0060455)
0.3 2.9 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 2.3 GO:0098885 maternal process involved in parturition(GO:0060137) modification of postsynaptic actin cytoskeleton(GO:0098885)
0.3 2.3 GO:0044838 cell quiescence(GO:0044838) response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.3 1.3 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.3 5.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 1.6 GO:0035094 response to nicotine(GO:0035094)
0.3 1.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 1.9 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.3 33.2 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.3 0.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.3 5.9 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.3 3.7 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.3 2.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.3 1.8 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.3 2.6 GO:0061117 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.3 2.9 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.3 2.3 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.3 10.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.3 3.1 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.3 2.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.3 0.8 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.3 0.5 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.3 1.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.3 1.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.3 0.8 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.3 3.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.3 5.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 0.8 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) positive regulation of Schwann cell migration(GO:1900149) positive regulation of glial cell migration(GO:1903977) regulation of dopaminergic neuron differentiation(GO:1904338)
0.3 0.8 GO:0060174 limb bud formation(GO:0060174)
0.3 1.8 GO:0032264 IMP salvage(GO:0032264)
0.3 8.5 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.3 1.5 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.3 3.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 1.3 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.2 1.5 GO:0090527 actin filament reorganization(GO:0090527)
0.2 3.7 GO:0051693 actin filament capping(GO:0051693)
0.2 4.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 0.5 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468)
0.2 1.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.2 0.2 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 1.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 0.7 GO:0021830 substrate-independent telencephalic tangential migration(GO:0021826) interneuron migration from the subpallium to the cortex(GO:0021830) substrate-independent telencephalic tangential interneuron migration(GO:0021843)
0.2 0.7 GO:0021852 pyramidal neuron migration(GO:0021852)
0.2 2.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.2 3.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 0.9 GO:0006586 tryptophan metabolic process(GO:0006568) indolalkylamine metabolic process(GO:0006586)
0.2 3.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 1.7 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.2 5.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.2 1.0 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.2 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 1.5 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.2 1.5 GO:1903044 protein localization to membrane raft(GO:1903044)
0.2 1.2 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.2 3.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 0.8 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.2 0.8 GO:0036089 cleavage furrow formation(GO:0036089)
0.2 1.9 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 2.1 GO:0042659 regulation of cell fate specification(GO:0042659)
0.2 0.6 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 0.9 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.2 2.6 GO:0023058 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.2 0.9 GO:0097646 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 1.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.8 GO:0009404 toxin metabolic process(GO:0009404)
0.2 1.3 GO:0030242 pexophagy(GO:0030242)
0.2 0.2 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
0.2 0.7 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.2 0.7 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 5.9 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.2 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 12.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 0.4 GO:0061055 myotome development(GO:0061055)
0.2 2.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 5.6 GO:0060612 adipose tissue development(GO:0060612)
0.2 1.7 GO:0006968 cellular defense response(GO:0006968)
0.2 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 6.2 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.2 16.7 GO:0018210 peptidyl-threonine modification(GO:0018210)
0.2 1.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 2.9 GO:0002931 response to ischemia(GO:0002931)
0.2 3.4 GO:0034063 stress granule assembly(GO:0034063)
0.2 1.0 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.2 0.8 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 7.9 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.2 0.2 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.2 1.1 GO:0006105 succinate metabolic process(GO:0006105)
0.2 1.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 1.6 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.2 1.1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.2 4.2 GO:0043171 peptide catabolic process(GO:0043171)
0.2 0.8 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.2 1.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 0.6 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.2 0.6 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.2 0.8 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 0.6 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.6 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.7 GO:0036438 regulation of heterotypic cell-cell adhesion(GO:0034114) positive regulation of heterotypic cell-cell adhesion(GO:0034116) maintenance of lens transparency(GO:0036438)
0.1 3.0 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.6 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.1 1.7 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 0.5 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 3.8 GO:0010259 multicellular organism aging(GO:0010259)
0.1 9.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 1.5 GO:0015809 arginine transport(GO:0015809)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 1.5 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 6.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.0 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 3.1 GO:0046677 response to antibiotic(GO:0046677)
0.1 1.6 GO:0051101 regulation of DNA binding(GO:0051101)
0.1 0.4 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 0.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 1.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.5 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.7 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.2 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 1.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.6 GO:0021592 fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)
0.1 1.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 8.3 GO:0007416 synapse assembly(GO:0007416)
0.1 0.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 2.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.7 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.5 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 1.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.9 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.6 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 1.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 1.0 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.5 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 1.1 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.6 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 2.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 0.8 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 1.1 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 4.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.2 GO:0097435 fibril organization(GO:0097435)
0.1 0.9 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.3 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 2.2 GO:0050770 regulation of axonogenesis(GO:0050770)
0.1 0.3 GO:2000778 positive regulation of interleukin-6 secretion(GO:2000778)
0.1 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.4 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 2.1 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.1 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.8 GO:0035690 cellular response to drug(GO:0035690)
0.1 1.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 1.1 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.1 4.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 0.8 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 4.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353) hydrogen sulfide biosynthetic process(GO:0070814)
0.1 1.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 1.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 2.6 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 0.4 GO:0007602 phototransduction(GO:0007602)
0.1 0.5 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.3 GO:0097369 sodium ion import(GO:0097369)
0.1 0.8 GO:0030851 granulocyte differentiation(GO:0030851)
0.1 0.4 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.4 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 1.0 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 6.1 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 3.6 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.5 GO:0070475 rRNA base methylation(GO:0070475)
0.0 3.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 3.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.6 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.4 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.9 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.5 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.6 GO:0033233 regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.0 0.4 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.8 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.4 GO:0055010 ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.0 0.4 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.0 1.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.2 GO:0098969 neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0 0.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 2.0 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.9 GO:0007568 aging(GO:0007568)
0.0 0.2 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.1 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.1 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 16.2 GO:0043512 inhibin A complex(GO:0043512)
4.6 13.8 GO:0072534 perineuronal net(GO:0072534)
4.4 17.8 GO:0031673 H zone(GO:0031673)
3.5 17.4 GO:0032437 cuticular plate(GO:0032437)
3.2 29.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
2.9 26.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.7 51.3 GO:0071564 npBAF complex(GO:0071564)
2.2 44.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
2.2 32.4 GO:0043083 synaptic cleft(GO:0043083)
1.9 21.0 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.9 78.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
1.8 5.4 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
1.8 26.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.7 8.5 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
1.7 22.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.7 33.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
1.5 5.9 GO:0097454 Schwann cell microvillus(GO:0097454)
1.4 28.9 GO:0031430 M band(GO:0031430)
1.3 5.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.2 20.8 GO:0031045 dense core granule(GO:0031045)
1.2 17.9 GO:1902711 GABA-A receptor complex(GO:1902711)
1.1 4.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.0 4.0 GO:0014802 terminal cisterna(GO:0014802)
1.0 3.0 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
1.0 2.9 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.9 10.0 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.9 14.2 GO:0005614 interstitial matrix(GO:0005614)
0.9 11.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.8 3.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.8 7.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.8 19.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.7 9.4 GO:0031672 A band(GO:0031672)
0.7 14.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.7 8.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.7 159.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.6 3.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.6 1.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.6 58.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.5 1.1 GO:0030478 actin cap(GO:0030478)
0.5 4.8 GO:0071565 nBAF complex(GO:0071565)
0.5 12.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.5 10.3 GO:0060077 inhibitory synapse(GO:0060077)
0.5 5.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.5 1.5 GO:0008091 spectrin(GO:0008091)
0.5 4.1 GO:0044294 dendritic growth cone(GO:0044294)
0.4 3.1 GO:0033263 CORVET complex(GO:0033263)
0.4 14.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 4.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.4 51.4 GO:0031225 anchored component of membrane(GO:0031225)
0.4 19.6 GO:0045171 intercellular bridge(GO:0045171)
0.3 41.3 GO:0030017 sarcomere(GO:0030017)
0.3 2.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 4.7 GO:0030673 axolemma(GO:0030673)
0.3 1.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.3 2.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 2.8 GO:0097165 nuclear stress granule(GO:0097165)
0.3 1.5 GO:0061574 ASAP complex(GO:0061574)
0.3 9.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 6.3 GO:0042734 presynaptic membrane(GO:0042734)
0.3 26.7 GO:0042641 actomyosin(GO:0042641)
0.3 2.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.3 13.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.3 1.3 GO:0070826 paraferritin complex(GO:0070826)
0.3 9.1 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.2 1.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 20.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 1.7 GO:0070695 FHF complex(GO:0070695)
0.2 7.0 GO:0044291 cell-cell contact zone(GO:0044291)
0.2 0.6 GO:0071437 invadopodium(GO:0071437)
0.2 1.1 GO:0000235 astral microtubule(GO:0000235)
0.2 1.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 3.1 GO:0042588 zymogen granule(GO:0042588)
0.2 4.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 2.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 4.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.2 3.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 0.9 GO:1903440 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648) calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 3.4 GO:0030315 T-tubule(GO:0030315)
0.2 1.8 GO:0001739 sex chromatin(GO:0001739)
0.2 4.4 GO:0035371 microtubule plus-end(GO:0035371)
0.2 2.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.2 2.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 36.4 GO:0098794 postsynapse(GO:0098794)
0.2 8.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 2.0 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 101.9 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.8 GO:0090543 Flemming body(GO:0090543)
0.1 10.5 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 6.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.3 GO:0031983 vesicle lumen(GO:0031983)
0.1 3.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 9.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 13.1 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 4.0 GO:0030175 filopodium(GO:0030175)
0.1 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 9.0 GO:0016605 PML body(GO:0016605)
0.1 1.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 7.6 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.6 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 10.8 GO:0001650 fibrillar center(GO:0001650)
0.1 0.3 GO:0001651 dense fibrillar component(GO:0001651)
0.1 5.5 GO:0030027 lamellipodium(GO:0030027)
0.1 0.7 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.1 25.6 GO:0045202 synapse(GO:0045202)
0.1 1.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 5.6 GO:0001726 ruffle(GO:0001726)
0.1 15.4 GO:0000139 Golgi membrane(GO:0000139)
0.1 4.8 GO:0005657 replication fork(GO:0005657)
0.1 1.9 GO:0012506 vesicle membrane(GO:0012506)
0.1 3.3 GO:0055037 recycling endosome(GO:0055037)
0.1 1.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.1 9.1 GO:0030424 axon(GO:0030424)
0.1 0.8 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.3 GO:0097361 CIA complex(GO:0097361)
0.1 0.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 3.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.0 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 11.1 GO:0005768 endosome(GO:0005768)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.6 GO:0005901 caveola(GO:0005901)
0.0 1.5 GO:0009986 cell surface(GO:0009986)
0.0 0.6 GO:0031252 cell leading edge(GO:0031252)
0.0 0.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 1.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 21.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
5.7 34.0 GO:0070699 type II activin receptor binding(GO:0070699)
5.3 21.1 GO:0030348 syntaxin-3 binding(GO:0030348)
4.3 17.4 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
3.8 30.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
3.4 17.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
3.2 25.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
3.2 9.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
2.9 11.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
2.6 10.5 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
2.3 36.5 GO:0003680 AT DNA binding(GO:0003680)
2.2 8.9 GO:0097109 neuroligin family protein binding(GO:0097109)
2.2 22.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
2.2 8.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
2.1 10.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
2.1 12.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.9 7.7 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
1.9 5.6 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
1.9 11.3 GO:0045545 syndecan binding(GO:0045545)
1.8 60.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
1.8 7.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
1.7 14.9 GO:0042043 neurexin family protein binding(GO:0042043)
1.6 1.6 GO:0098821 BMP receptor activity(GO:0098821)
1.6 12.6 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
1.5 87.9 GO:0036002 pre-mRNA binding(GO:0036002)
1.4 7.2 GO:0038132 neuregulin binding(GO:0038132)
1.4 17.1 GO:0038191 neuropilin binding(GO:0038191)
1.4 33.5 GO:0004385 guanylate kinase activity(GO:0004385)
1.4 41.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.4 16.3 GO:0050897 cobalt ion binding(GO:0050897)
1.3 33.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
1.3 13.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.3 4.0 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
1.3 5.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.3 2.6 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.3 3.8 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.2 71.4 GO:0030507 spectrin binding(GO:0030507)
1.2 8.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.2 3.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
1.2 5.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.1 12.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
1.1 19.0 GO:0004890 GABA-A receptor activity(GO:0004890)
1.0 3.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.0 3.0 GO:0004111 creatine kinase activity(GO:0004111)
1.0 3.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.0 3.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.0 30.1 GO:0070412 R-SMAD binding(GO:0070412)
0.9 28.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.9 3.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.9 6.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.9 16.8 GO:0030506 ankyrin binding(GO:0030506)
0.9 6.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.9 3.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.9 15.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.8 0.8 GO:1990715 mRNA CDS binding(GO:1990715)
0.8 5.8 GO:0032051 clathrin light chain binding(GO:0032051)
0.8 2.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.8 4.1 GO:0004359 glutaminase activity(GO:0004359)
0.8 11.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.8 3.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.8 3.8 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.8 2.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.8 9.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.7 8.1 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.7 12.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.7 2.8 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.7 3.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.7 11.2 GO:0046625 sphingolipid binding(GO:0046625)
0.7 2.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.6 14.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.6 4.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.6 10.4 GO:0030275 LRR domain binding(GO:0030275)
0.6 1.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.6 2.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.6 4.8 GO:0002162 dystroglycan binding(GO:0002162)
0.6 2.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.6 7.0 GO:0004000 adenosine deaminase activity(GO:0004000)
0.6 1.7 GO:0019966 C-X-C chemokine binding(GO:0019958) interleukin-1 binding(GO:0019966) tumor necrosis factor binding(GO:0043120)
0.6 1.7 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.6 3.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 2.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.6 12.2 GO:0042805 actinin binding(GO:0042805)
0.5 12.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 2.6 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5 26.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.5 4.7 GO:0005523 tropomyosin binding(GO:0005523)
0.5 2.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.5 12.4 GO:0042287 MHC protein binding(GO:0042287)
0.5 1.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.5 4.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 1.4 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.4 1.8 GO:0016595 glutamate binding(GO:0016595)
0.4 4.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 2.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 2.9 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.4 4.9 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.4 3.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4 3.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.4 1.8 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.4 2.6 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.4 1.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 1.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 1.4 GO:0001847 opsonin receptor activity(GO:0001847)
0.4 23.4 GO:0005262 calcium channel activity(GO:0005262)
0.3 1.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3 2.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.3 1.7 GO:0055100 adiponectin binding(GO:0055100)
0.3 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.3 6.7 GO:0043422 protein kinase B binding(GO:0043422)
0.3 2.6 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3 1.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 4.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.3 56.5 GO:0004386 helicase activity(GO:0004386)
0.3 2.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.3 14.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.3 0.3 GO:0070052 collagen V binding(GO:0070052)
0.3 0.9 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.3 2.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.3 0.8 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.3 2.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 2.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 3.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 1.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.3 29.9 GO:0005057 receptor signaling protein activity(GO:0005057)
0.3 1.3 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.3 10.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 7.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 2.9 GO:0050692 DBD domain binding(GO:0050692)
0.3 1.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 3.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 0.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 1.7 GO:0031419 cobalamin binding(GO:0031419)
0.2 12.2 GO:0030276 clathrin binding(GO:0030276)
0.2 0.7 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 58.1 GO:0008017 microtubule binding(GO:0008017)
0.2 5.1 GO:0001968 fibronectin binding(GO:0001968)
0.2 3.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 1.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 1.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 2.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 1.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 5.3 GO:0070064 proline-rich region binding(GO:0070064)
0.2 3.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 15.7 GO:0030674 protein binding, bridging(GO:0030674)
0.2 2.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.2 3.3 GO:0031489 myosin V binding(GO:0031489)
0.2 1.6 GO:0046790 virion binding(GO:0046790)
0.2 8.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 1.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 0.6 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 20.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 4.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.2 0.9 GO:0097643 amylin receptor activity(GO:0097643)
0.2 1.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.2 1.8 GO:0042562 hormone binding(GO:0042562)
0.2 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 1.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 4.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.2 1.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 3.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 0.6 GO:0050733 RS domain binding(GO:0050733)
0.2 15.3 GO:0005516 calmodulin binding(GO:0005516)
0.2 1.1 GO:0015288 porin activity(GO:0015288)
0.1 4.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 2.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 5.6 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 1.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.8 GO:0043394 proteoglycan binding(GO:0043394)
0.1 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 3.1 GO:0008009 chemokine activity(GO:0008009)
0.1 2.7 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 5.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 2.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 4.2 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 1.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.4 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.8 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 2.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 4.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 2.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 27.4 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.8 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 1.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 3.6 GO:0019894 kinesin binding(GO:0019894)
0.1 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.9 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 2.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 11.0 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 25.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 12.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.6 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 1.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 2.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 2.5 GO:0015485 cholesterol binding(GO:0015485)
0.1 3.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 1.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.5 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.1 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970) extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 0.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 2.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.8 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 9.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0003924 GTPase activity(GO:0003924)
0.0 0.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 2.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 2.2 GO:0003779 actin binding(GO:0003779)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 81.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
1.0 43.9 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.9 31.1 PID_IL3_PATHWAY IL3-mediated signaling events
0.8 9.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.8 29.9 PID_ERBB4_PATHWAY ErbB4 signaling events
0.6 3.6 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.6 8.3 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.5 17.9 PID_ALK1_PATHWAY ALK1 signaling events
0.5 7.1 ST_GA12_PATHWAY G alpha 12 Pathway
0.5 19.9 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.5 19.4 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.5 5.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.5 16.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.4 12.7 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.4 18.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 9.3 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.4 24.3 PID_LKB1_PATHWAY LKB1 signaling events
0.4 21.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.3 15.1 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.3 9.5 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.3 14.9 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.3 14.9 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.3 11.1 PID_FGF_PATHWAY FGF signaling pathway
0.3 10.8 PID_TNF_PATHWAY TNF receptor signaling pathway
0.3 6.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.2 7.9 PID_CDC42_PATHWAY CDC42 signaling events
0.2 4.5 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.2 3.5 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.2 1.5 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.2 4.7 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.2 3.0 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 16.4 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.2 6.2 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.2 6.3 PID_INSULIN_PATHWAY Insulin Pathway
0.2 2.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.2 3.2 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.2 6.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.2 1.2 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 8.0 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 1.2 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 1.7 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.1 5.0 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 8.6 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 15.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.9 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 1.2 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.1 0.9 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 1.9 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 0.9 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.1 1.2 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.1 1.1 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 1.8 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 0.6 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.3 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 1.1 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.1 0.2 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.8 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.3 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.2 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.3 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.5 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.3 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 1.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 16.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
2.5 25.4 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
2.0 71.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
2.0 84.0 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
1.7 46.6 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
1.5 18.9 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
1.4 37.6 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.2 22.9 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.8 21.4 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.7 9.0 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.7 12.9 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.7 4.1 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.6 8.4 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.6 7.7 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.6 6.7 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.6 16.0 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.6 8.1 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.6 45.3 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.6 24.6 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.5 3.1 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 3.5 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.4 1.3 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.4 3.9 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.4 7.7 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.4 7.7 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.4 3.2 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.4 35.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3 8.1 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.3 6.7 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.3 7.3 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.3 10.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.3 21.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.3 2.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 2.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 1.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.2 2.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 2.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.2 2.9 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 2.0 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 1.5 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 7.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 1.7 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.2 1.6 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.2 2.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 3.2 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.2 1.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 2.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 1.1 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.1 3.2 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 1.5 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.1 3.1 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.5 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.7 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.5 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 11.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.9 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 6.2 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.7 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 0.9 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 6.2 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.1 2.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.5 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 5.0 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 1.8 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 0.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.1 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.1 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 3.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 3.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.4 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 1.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.2 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.1 1.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.9 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.8 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.5 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 2.5 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.8 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.6 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME_SIGNALING_BY_ERBB2 Genes involved in Signaling by ERBB2
0.0 0.5 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.5 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME_G1_PHASE Genes involved in G1 Phase