Motif ID: Hoxd10

Z-value: 0.477


Transcription factors associated with Hoxd10:

Gene SymbolEntrez IDGene Name
Hoxd10 ENSMUSG00000050368.3 Hoxd10



Activity profile for motif Hoxd10.

activity profile for motif Hoxd10


Sorted Z-values histogram for motif Hoxd10

Sorted Z-values for motif Hoxd10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd10

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 41 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_27790947 4.131 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr3_-_80802789 2.065 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr2_+_65620829 1.497 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr4_+_102254993 1.445 ENSMUST00000106908.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr8_-_84773381 1.405 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr7_+_96210107 1.059 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr17_-_78684262 1.033 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chrX_-_70365052 0.973 ENSMUST00000101509.2
 Ids
iduronate 2-sulfatase
chr3_+_55461758 0.959 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr18_-_78123324 0.873 ENSMUST00000160292.1
ENSMUST00000091813.5
 Slc14a1

solute carrier family 14 (urea transporter), member 1

chr3_+_86084434 0.852 ENSMUST00000107664.2
 Sh3d19
SH3 domain protein D19
chr15_+_9140527 0.834 ENSMUST00000090380.4
 Lmbrd2
LMBR1 domain containing 2
chr10_+_69534039 0.771 ENSMUST00000182557.1
 Ank3
ankyrin 3, epithelial
chr1_+_180111339 0.577 ENSMUST00000145181.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chrX_+_66653003 0.562 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr7_+_30095150 0.547 ENSMUST00000130526.1
ENSMUST00000108200.1
 Zfp260

zinc finger protein 260

chr6_+_33249085 0.539 ENSMUST00000052266.8
ENSMUST00000090381.4
ENSMUST00000115080.1
 Exoc4


exocyst complex component 4


chr14_-_93888732 0.475 ENSMUST00000068992.2
 Pcdh9
protocadherin 9
chr9_+_95857597 0.450 ENSMUST00000034980.7
 Atr
ataxia telangiectasia and Rad3 related
chr17_-_46327949 0.444 ENSMUST00000047970.7
 Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 1.1 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.0 1.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.3 0.9 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.6 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.2 0.5 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.5 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)

Gene overrepresentation in molecular_function category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 1.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.1 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 0.9 GO:0015265 urea channel activity(GO:0015265)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.5 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.0 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 1.0 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.9 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing