Motif ID: Hoxd9

Z-value: 0.623


Transcription factors associated with Hoxd9:

Gene SymbolEntrez IDGene Name
Hoxd9 ENSMUSG00000043342.8 Hoxd9



Activity profile for motif Hoxd9.

activity profile for motif Hoxd9


Sorted Z-values histogram for motif Hoxd9

Sorted Z-values for motif Hoxd9



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd9

PNG image of the network

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Top targets:


Showing 1 to 20 of 100 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_65014904 2.534 ENSMUST00000110100.2
 Gm21961
predicted gene, 21961
chr13_-_41273977 1.941 ENSMUST00000163881.1
 Gm17364
predicted gene, 17364
chr11_+_29373618 1.909 ENSMUST00000040182.6
ENSMUST00000109477.1
 Ccdc88a

coiled coil domain containing 88A

chr14_-_100149764 1.568 ENSMUST00000097079.4
 Klf12
Kruppel-like factor 12
chr17_-_78684262 1.509 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr13_-_74376566 1.304 ENSMUST00000091481.2
 Zfp72
zinc finger protein 72
chr2_+_67748212 1.243 ENSMUST00000180887.1
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr8_+_84723003 1.208 ENSMUST00000098571.4
 G430095P16Rik
RIKEN cDNA G430095P16 gene
chr14_-_36919314 1.092 ENSMUST00000182797.1
 Ccser2
coiled-coil serine rich 2
chr1_+_180111339 1.079 ENSMUST00000145181.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr7_-_14562171 1.069 ENSMUST00000181796.1
 Vmn1r90
vomeronasal 1 receptor 90
chr7_+_66365905 1.050 ENSMUST00000107486.1
 Gm10974
predicted gene 10974
chr2_+_65620829 1.042 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr19_-_57197435 0.949 ENSMUST00000111550.1
 Ablim1
actin-binding LIM protein 1
chr3_+_35754121 0.933 ENSMUST00000108186.1
ENSMUST00000029257.8
 Atp11b

ATPase, class VI, type 11B

chr3_+_53845086 0.929 ENSMUST00000108014.1
 Gm10985
predicted gene 10985
chr8_+_66386292 0.909 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr2_-_63184253 0.900 ENSMUST00000075052.3
ENSMUST00000112454.1
 Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr19_-_57197377 0.877 ENSMUST00000111546.1
 Ablim1
actin-binding LIM protein 1
chr7_-_103827922 0.876 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.4 1.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 1.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 1.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.1 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 1.1 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 1.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.8 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.6 GO:0035989 tendon development(GO:0035989)
0.1 0.6 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.6 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.2 0.5 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.2 0.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.5 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0042641 actomyosin(GO:0042641)
0.0 1.9 GO:0005814 centriole(GO:0005814)
0.1 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 0.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.5 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 1.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 0.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.0 0.9 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 0.6 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.1 0.6 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)

Gene overrepresentation in C2:CP category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.1 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.7 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.6 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.4 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors