Motif ID: Id4
Z-value: 1.111
Transcription factors associated with Id4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Id4 | ENSMUSG00000021379.1 | Id4 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Id4 | mm10_v2_chr13_+_48261427_48261427 | -0.33 | 1.8e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 347 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 5.9 | GO:0046959 | habituation(GO:0046959) |
| 0.1 | 5.0 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.2 | 4.7 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.1 | 4.7 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 1.5 | 4.5 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
| 1.4 | 4.3 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
| 0.9 | 3.7 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 0.1 | 3.7 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 1.1 | 3.4 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 0.4 | 3.3 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.1 | 3.3 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.4 | 3.0 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 1.0 | 2.9 | GO:0070650 | actin filament bundle distribution(GO:0070650) |
| 0.1 | 2.9 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 2.9 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.7 | 2.8 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.5 | 2.8 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 0.2 | 2.8 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.1 | 2.8 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.7 | 2.7 | GO:0060032 | notochord regression(GO:0060032) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 147 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 12.1 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 8.1 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 6.5 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.0 | 5.3 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.3 | 5.1 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 4.5 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.9 | 4.3 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 0.6 | 3.7 | GO:0016011 | dystroglycan complex(GO:0016011) |
| 0.2 | 3.3 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 3.3 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.5 | 2.9 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.1 | 2.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 2.7 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 2.7 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.1 | 2.7 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.7 | 2.6 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.7 | 2.6 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.0 | 2.4 | GO:0030175 | filopodium(GO:0030175) |
| 0.3 | 2.3 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.1 | 2.3 | GO:0060077 | inhibitory synapse(GO:0060077) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 220 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.2 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.2 | 5.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 5.6 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.2 | 5.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.3 | 4.4 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 4.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 3.9 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.4 | 3.7 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.3 | 3.4 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 3.4 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.8 | 3.3 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.2 | 3.2 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 3.2 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.2 | 2.9 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 2.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 2.9 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.2 | 2.8 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.0 | 2.8 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.1 | 2.7 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.9 | 2.6 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 59 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.0 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 6.6 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.1 | 5.9 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 4.7 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.0 | 4.5 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 3.9 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.1 | 3.9 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.1 | 3.8 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 3.8 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.4 | 3.1 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
| 0.1 | 3.0 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.1 | 2.9 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 2.9 | PID_RHOA_PATHWAY | RhoA signaling pathway |
| 0.1 | 2.8 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 2.5 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.1 | 2.4 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 2.4 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.1 | 1.8 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 1.8 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
| 0.0 | 1.8 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 87 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.7 | REACTOME_ION_CHANNEL_TRANSPORT | Genes involved in Ion channel transport |
| 0.2 | 5.3 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 4.6 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.1 | 4.3 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 4.2 | REACTOME_INWARDLY_RECTIFYING_K_CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.1 | 4.1 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
| 0.1 | 4.0 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.2 | 3.9 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 3.5 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 3.3 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.1 | 2.8 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 2.7 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 2.7 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.4 | 2.6 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.3 | 2.3 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.1 | 2.3 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.1 | 2.2 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 2.1 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 2.0 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.1 | 2.0 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
