Motif ID: Ikzf2

Z-value: 0.635


Transcription factors associated with Ikzf2:

Gene SymbolEntrez IDGene Name
Ikzf2 ENSMUSG00000025997.7 Ikzf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ikzf2mm10_v2_chr1_-_69685937_69685966-0.058.4e-01Click!


Activity profile for motif Ikzf2.

activity profile for motif Ikzf2


Sorted Z-values histogram for motif Ikzf2

Sorted Z-values for motif Ikzf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ikzf2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 110 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_103422010 3.414 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr6_-_23248264 3.373 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr5_-_123141067 1.307 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
 AI480526


expressed sequence AI480526


chr1_+_45311538 1.088 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr6_+_15185203 0.856 ENSMUST00000154448.1
 Foxp2
forkhead box P2
chr8_-_89147247 0.575 ENSMUST00000177870.1
 Gm6625
predicted gene 6625
chr1_-_45503282 0.573 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr1_+_107511489 0.557 ENSMUST00000064916.2
 Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr5_-_123140135 0.553 ENSMUST00000160099.1
 AI480526
expressed sequence AI480526
chr14_+_64589802 0.517 ENSMUST00000180610.1
 A930011O12Rik
RIKEN cDNA A930011O12 gene
chrX_+_106920618 0.496 ENSMUST00000060576.7
 Lpar4
lysophosphatidic acid receptor 4
chr3_-_154330543 0.492 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr5_+_30913398 0.482 ENSMUST00000031055.5
 Emilin1
elastin microfibril interfacer 1
chr6_+_4003926 0.445 ENSMUST00000031670.8
 Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr9_-_13446753 0.441 ENSMUST00000167906.2
 Gm17571
predicted gene, 17571
chr3_+_88214474 0.439 ENSMUST00000181356.1
ENSMUST00000181396.1
 Gm3764

predicted gene 3764

chr2_+_103970115 0.436 ENSMUST00000111143.1
ENSMUST00000138815.1
 Lmo2

LIM domain only 2

chr2_+_103970221 0.412 ENSMUST00000111140.2
ENSMUST00000111139.2
 Lmo2

LIM domain only 2

chr13_-_103764502 0.401 ENSMUST00000074616.5
 Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr17_-_56571438 0.379 ENSMUST00000131056.1
 Safb2
scaffold attachment factor B2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 1.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.9 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.7 GO:0051451 myoblast migration(GO:0051451)
0.2 0.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.4 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.2 GO:0045004 DNA replication proofreading(GO:0045004)
0.1 0.2 GO:0072284 cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.7 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 0.6 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.8 GO:0043425 bHLH transcription factor binding(GO:0043425) E-box binding(GO:0070888)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.1 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.5 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions