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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_57072024	1.158	ENSMUST00000169879.1	Sin3a	transcriptional regulator, SIN3A (yeast)
chr17_+_23679363	0.868	ENSMUST00000024699.2	Cldn6	claudin 6
chr19_+_5568002	0.866	ENSMUST00000096318.3	Ap5b1	adaptor-related protein complex 5, beta 1 subunit
chr11_+_88999376	0.820	ENSMUST00000100627.2 ENSMUST00000107896.3 ENSMUST00000000284.6	Trim25	tripartite motif-containing 25
chrX_-_95444789	0.772	ENSMUST00000084535.5	Amer1	APC membrane recruitment 1
chr11_+_72689997	0.754	ENSMUST00000155998.1	Ankfy1	ankyrin repeat and FYVE domain containing 1
chr16_-_35939082	0.746	ENSMUST00000081933.7 ENSMUST00000114885.1	Dtx3l	deltex 3-like (Drosophila)
chr6_-_39118211	0.600	ENSMUST00000038398.6	Parp12	poly (ADP-ribose) polymerase family, member 12
chr17_-_6782775	0.522	ENSMUST00000064234.6	Ezr	ezrin
chr9_+_95954744	0.519	ENSMUST00000034981.7	Xrn1	5'-3' exoribonuclease 1
chr6_-_13608011	0.437	ENSMUST00000031554.2	Tmem168	transmembrane protein 168
chr7_-_126396715	0.372	ENSMUST00000075671.4	Nfatc2ip	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
chr16_+_35938972	0.372	ENSMUST00000023622.6 ENSMUST00000114877.1	Parp9	poly (ADP-ribose) polymerase family, member 9
chr4_-_40239779	0.334	ENSMUST00000037907.6	Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr19_-_7295394	0.329	ENSMUST00000025921.8	Mark2	MAP/microtubule affinity-regulating kinase 2
chr9_+_45042425	0.324	ENSMUST00000034600.4	Mpzl2	myelin protein zero-like 2
chr9_-_123851855	0.286	ENSMUST00000184082.1 ENSMUST00000167595.2	Fyco1	FYVE and coiled-coil domain containing 1
chr9_-_14381242	0.265	ENSMUST00000167549.1	Endod1	endonuclease domain containing 1
chr12_-_31950170	0.263	ENSMUST00000176520.1	Hbp1	high mobility group box transcription factor 1
chr2_-_69586021	0.246	ENSMUST00000100051.2 ENSMUST00000092551.4 ENSMUST00000080953.5	Lrp2	low density lipoprotein receptor-related protein 2
chr16_+_35938470	0.236	ENSMUST00000114878.1	Parp9	poly (ADP-ribose) polymerase family, member 9
chr4_-_58911902	0.222	ENSMUST00000134848.1 ENSMUST00000107557.2 ENSMUST00000149301.1	AI314180	expressed sequence AI314180
chr5_+_92809372	0.215	ENSMUST00000113054.2	Shroom3	shroom family member 3
chr11_-_86201144	0.202	ENSMUST00000044423.3	Brip1	BRCA1 interacting protein C-terminal helicase 1
chr1_+_52119438	0.198	ENSMUST00000070968.7	Stat1	signal transducer and activator of transcription 1
chr12_-_31950210	0.190	ENSMUST00000176084.1 ENSMUST00000176103.1 ENSMUST00000167458.2	Hbp1	high mobility group box transcription factor 1
chr17_-_34862473	0.183	ENSMUST00000025229.4 ENSMUST00000176203.2 ENSMUST00000128767.1	Cfb	complement factor B
chr7_+_128523576	0.181	ENSMUST00000033136.7	Bag3	BCL2-associated athanogene 3
chr7_+_49246131	0.177	ENSMUST00000064395.6	Nav2	neuron navigator 2
chr3_-_142395661	0.166	ENSMUST00000029941.9 ENSMUST00000168967.2 ENSMUST00000090134.5 ENSMUST00000058626.8	Pdlim5	PDZ and LIM domain 5
chr11_+_60699718	0.164	ENSMUST00000052346.3	Llgl1	lethal giant larvae homolog 1 (Drosophila)
chr11_+_69966896	0.156	ENSMUST00000151515.1	Cldn7	claudin 7
chr11_+_60699758	0.154	ENSMUST00000108719.3	Llgl1	lethal giant larvae homolog 1 (Drosophila)
chr16_-_91646906	0.152	ENSMUST00000120450.1 ENSMUST00000023684.7	Gart	phosphoribosylglycinamide formyltransferase
chr15_+_96287518	0.139	ENSMUST00000134985.2 ENSMUST00000096250.4	Arid2	AT rich interactive domain 2 (ARID, RFX-like)
chr7_+_83755904	0.137	ENSMUST00000051522.8 ENSMUST00000042280.7	Gm7964	predicted gene 7964
chr12_-_78980758	0.132	ENSMUST00000174072.1	Tmem229b	transmembrane protein 229B
chr7_-_65370908	0.129	ENSMUST00000032729.6	Tjp1	tight junction protein 1
chr2_-_51934644	0.125	ENSMUST00000165313.1	Rbm43	RNA binding motif protein 43
chr17_+_31433054	0.122	ENSMUST00000136384.1	Pde9a	phosphodiesterase 9A
chr6_+_57580992	0.116	ENSMUST00000031817.8	Herc6	hect domain and RLD 6
chrX_+_77511002	0.106	ENSMUST00000088217.5	Tbl1x	transducin (beta)-like 1 X-linked
chr2_-_77519565	0.106	ENSMUST00000111830.2	Zfp385b	zinc finger protein 385B
chr10_-_43174521	0.098	ENSMUST00000040275.7	Sobp	sine oculis-binding protein homolog (Drosophila)
chr5_+_99979061	0.095	ENSMUST00000046721.1	4930524J08Rik	RIKEN cDNA 4930524J08 gene
chr12_+_26469204	0.088	ENSMUST00000020969.3	Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr7_-_141266415	0.083	ENSMUST00000106023.1 ENSMUST00000097952.2 ENSMUST00000026571.4	Irf7	interferon regulatory factor 7
chr5_-_99978914	0.082	ENSMUST00000112939.3 ENSMUST00000171786.1 ENSMUST00000072750.6 ENSMUST00000019128.8 ENSMUST00000172361.1	Hnrnpd	heterogeneous nuclear ribonucleoprotein D
chr17_+_34644805	0.081	ENSMUST00000174796.1	Fkbpl	FK506 binding protein-like
chrX_+_37126777	0.075	ENSMUST00000016553.4	Nkap	NFKB activating protein
chr4_-_40239700	0.064	ENSMUST00000142055.1	Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr2_-_77170592	0.062	ENSMUST00000164114.2 ENSMUST00000049544.7	Ccdc141	coiled-coil domain containing 141
chr12_-_31950535	0.052	ENSMUST00000172314.2	Hbp1	high mobility group box transcription factor 1
chr4_-_46536096	0.051	ENSMUST00000102924.2	Trim14	tripartite motif-containing 14
chr9_+_20868628	0.051	ENSMUST00000043911.7	A230050P20Rik	RIKEN cDNA A230050P20 gene
chr11_-_78984831	0.047	ENSMUST00000073001.4 ENSMUST00000108269.3	Lgals9	lectin, galactose binding, soluble 9
chr16_-_67620805	0.046	ENSMUST00000120594.1	Cadm2	cell adhesion molecule 2
chr15_+_99126513	0.036	ENSMUST00000063517.4	Spats2	spermatogenesis associated, serine-rich 2
chr17_+_34203527	0.035	ENSMUST00000025197.5	Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_+_101582236	0.031	ENSMUST00000039581.7 ENSMUST00000100403.2 ENSMUST00000107194.1 ENSMUST00000128614.1	Tmem106a	transmembrane protein 106A
chr11_-_78984946	0.031	ENSMUST00000108268.3	Lgals9	lectin, galactose binding, soluble 9
chr3_+_142496924	0.024	ENSMUST00000090127.2	Gbp5	guanylate binding protein 5
chr15_-_76243401	0.023	ENSMUST00000165738.1 ENSMUST00000075689.6	Parp10	poly (ADP-ribose) polymerase family, member 10
chr17_-_78882508	0.019	ENSMUST00000024884.4	Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2
chr3_+_138065052	0.014	ENSMUST00000163080.2	1110002E22Rik	RIKEN cDNA 1110002E22 gene
chrM_+_8600	0.013	ENSMUST00000082409.1	mt-Co3	mitochondrially encoded cytochrome c oxidase III
chrX_-_101222426	0.009	ENSMUST00000120389.1 ENSMUST00000156473.1 ENSMUST00000077876.3	Snx12	sorting nexin 12
chr12_-_73113407	0.002	ENSMUST00000175693.1	Six4	sine oculis-related homeobox 4
chr9_-_123862023	0.001	ENSMUST00000182350.1 ENSMUST00000078755.2	Xcr1	chemokine (C motif) receptor 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:1901675	negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2	0.5	GO:1900041	intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.1	0.8	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1	0.8	GO:0032439	endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.1	0.4	GO:0009597	detection of virus(GO:0009597)
0.1	0.3	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.1	0.6	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.1	0.5	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	0.2	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.0	0.8	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.0	0.5	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.2	GO:0021564	glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.0	0.2	GO:0051026	chiasma assembly(GO:0051026)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.2	GO:0046654	'de novo' IMP biosynthetic process(GO:0006189) tetrahydrofolate biosynthetic process(GO:0046654)
0.0	0.1	GO:0046077	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0	0.1	GO:1901355	response to rapamycin(GO:1901355)
0.0	0.1	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.0	0.3	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090)
0.0	0.1	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0	0.7	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.2	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.0	GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.1	GO:0060982	coronary artery morphogenesis(GO:0060982)
0.0	0.2	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.1	0.8	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	1.2	GO:0016580	Sin3 complex(GO:0016580)
0.1	1.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.3	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.3	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.9	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.1	0.2	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.1	0.9	GO:0001618	virus receptor activity(GO:0001618)
0.1	1.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.2	GO:0004637	phosphoribosylamine-glycine ligase activity(GO:0004637)
0.0	0.8	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.5	GO:0044548	S100 protein binding(GO:0044548)
0.0	1.2	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.0	0.4	GO:0031386	protein tag(GO:0031386)
0.0	0.2	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.2	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.3	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.2	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.8	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	ST_TYPE_I_INTERFERON_PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.5	PID_SYNDECAN_2_PATHWAY	Syndecan-2-mediated signaling events
0.0	0.5	PID_MYC_PATHWAY	C-MYC pathway
0.0	1.2	PID_HEDGEHOG_GLI_PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.2	PID_HEDGEHOG_2PATHWAY	Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.2	REACTOME_REGULATION_OF_COMPLEMENT_CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.0	REACTOME_TIGHT_JUNCTION_INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.5	REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.1	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.2	REACTOME_STEROID_HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME_IL_6_SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.5	REACTOME_RECYCLING_PATHWAY_OF_L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis

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