Motif ID: Irx4

Z-value: 0.268


Transcription factors associated with Irx4:

Gene SymbolEntrez IDGene Name
Irx4 ENSMUSG00000021604.9 Irx4



Activity profile for motif Irx4.

activity profile for motif Irx4


Sorted Z-values histogram for motif Irx4

Sorted Z-values for motif Irx4



Network of associatons between targets according to the STRING database.


Top targets:


Showing 1 to 13 of 13 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_45311538 1.171 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr6_-_3494587 0.623 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr8_+_84872105 0.473 ENSMUST00000136026.1
ENSMUST00000170296.1
 Syce2

synaptonemal complex central element protein 2

chr9_-_58202281 0.421 ENSMUST00000163897.1
 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr2_-_79908428 0.408 ENSMUST00000102652.3
ENSMUST00000102651.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr6_-_83317589 0.330 ENSMUST00000005810.6
 Mthfd2
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr11_-_11970540 0.326 ENSMUST00000109653.1
 Grb10
growth factor receptor bound protein 10
chr15_-_35938186 0.320 ENSMUST00000014457.8
 Cox6c
cytochrome c oxidase subunit VIc
chr2_-_79908389 0.316 ENSMUST00000090756.4
 Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr15_-_35938009 0.250 ENSMUST00000156915.1
 Cox6c
cytochrome c oxidase subunit VIc
chr3_-_57651667 0.217 ENSMUST00000160959.1
 Commd2
COMM domain containing 2
chr17_-_27133902 0.197 ENSMUST00000119227.1
ENSMUST00000025045.8
 Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2

chr16_+_17146937 0.123 ENSMUST00000115706.1
ENSMUST00000069064.4
 Ydjc

YdjC homolog (bacterial)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.3 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)

Gene overrepresentation in cellular_component category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.5 GO:0000801 central element(GO:0000801)

Gene overrepresentation in molecular_function category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 NABA_COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation