ISMARA results: Klf13

Motif ID: Klf13

Z-value: 0.640

Transcription factors associated with Klf13:

Gene Symbol	Entrez ID	Gene Name
Klf13	ENSMUSG00000052040.9	Klf13

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Klf13	mm10_v2_chr7_-_63938862_63938933	-0.41	8.8e-02	Click!

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Showing 1 to 20 of 92 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_-_87282771	1.063	ENSMUST00000161759.1	4833418N02Rik	RIKEN cDNA 4833418N02 gene
chr19_+_56722372	0.974	ENSMUST00000038949.4	Adrb1	adrenergic receptor, beta 1
chr11_-_76399107	0.942	ENSMUST00000021204.3	Nxn	nucleoredoxin
chr4_-_126736236	0.927	ENSMUST00000048194.7	Tfap2e	transcription factor AP-2, epsilon
chr17_-_87282793	0.918	ENSMUST00000146560.2	4833418N02Rik	RIKEN cDNA 4833418N02 gene
chr17_+_87282880	0.774	ENSMUST00000041110.5 ENSMUST00000125875.1	Ttc7	tetratricopeptide repeat domain 7
chr11_+_44617310	0.749	ENSMUST00000081265.5 ENSMUST00000101326.3 ENSMUST00000109268.1	Ebf1	early B cell factor 1
chr19_-_42129043	0.736	ENSMUST00000018965.3	Avpi1	arginine vasopressin-induced 1
chr19_-_42128982	0.686	ENSMUST00000161873.1	Avpi1	arginine vasopressin-induced 1
chr6_+_137754529	0.625	ENSMUST00000087675.6	Dera	2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr4_-_117133953	0.598	ENSMUST00000076859.5	Plk3	polo-like kinase 3
chr17_-_56757516	0.554	ENSMUST00000044752.5	Nrtn	neurturin
chr17_+_56717759	0.512	ENSMUST00000002452.6	Ndufa11	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11
chr7_-_30563184	0.504	ENSMUST00000043898.6	Psenen	presenilin enhancer 2 homolog (C. elegans)
chr17_+_35059035	0.495	ENSMUST00000007255.6 ENSMUST00000174493.1	Ddah2	dimethylarginine dimethylaminohydrolase 2
chr15_+_85037062	0.439	ENSMUST00000023069.7	Fam118a	family with sequence similarity 118, member A
chr11_+_116532441	0.419	ENSMUST00000106386.1 ENSMUST00000145737.1 ENSMUST00000155102.1 ENSMUST00000063446.6	Sphk1	sphingosine kinase 1
chr12_-_79172609	0.418	ENSMUST00000055262.6	Vti1b	vesicle transport through interaction with t-SNAREs 1B
chr14_-_118706180	0.413	ENSMUST00000036554.6 ENSMUST00000166646.1	Abcc4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr14_+_54426902	0.398	ENSMUST00000010550.7	Mrpl52	mitochondrial ribosomal protein L52

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 41 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.4	GO:0000187	activation of MAPK activity(GO:0000187)
0.3	1.0	GO:1900133	renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.1	0.9	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.0	0.9	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.8	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.2	0.6	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.6	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.0	0.6	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0	0.6	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.5	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.5	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.5	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1	0.4	GO:0032915	positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0	0.4	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.4	GO:0046512	sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0	0.4	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.4	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.4	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.4	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.1	0.3	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)

Gene overrepresentation in cellular_component category:

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Showing 1 to 17 of 17 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.5	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	0.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.4	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1	0.4	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.4	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.4	GO:0035861	site of double-strand break(GO:0035861)
0.1	0.3	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.3	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.3	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.3	GO:0031011	Ino80 complex(GO:0031011)
0.0	0.3	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	0.2	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.2	GO:0099524	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0	0.2	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)

Gene overrepresentation in molecular_function category:

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Showing 1 to 20 of 27 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0051379	epinephrine binding(GO:0051379)
0.3	0.9	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.2	0.9	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.1	0.7	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.6	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	0.4	GO:0017050	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	0.4	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.4	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.4	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.4	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.4	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.3	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.3	GO:0000213	tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.3	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.3	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.3	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0	0.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.3	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.1	0.2	GO:0030348	syntaxin-3 binding(GO:0030348)

Gene overrepresentation in C2:CP category:

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Showing 1 to 6 of 6 entries

Total log-likelihood	Term	Description
0.8	ST_MYOCYTE_AD_PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.5	PID_SYNDECAN_3_PATHWAY	Syndecan-3-mediated signaling events
0.4	PID_S1P_META_PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.4	SA_B_CELL_RECEPTOR_COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3	PID_LPA4_PATHWAY	LPA4-mediated signaling events
0.3	PID_SMAD2_3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 11 of 11 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	1.0	REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.9	REACTOME_RESPIRATORY_ELECTRON_TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.6	REACTOME_NCAM1_INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.5	REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.4	REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.4	REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.4	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.3	REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.1	REACTOME_ENDOGENOUS_STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism