Motif ID: Lhx2_Hoxc5

Z-value: 0.572

Transcription factors associated with Lhx2_Hoxc5:

Gene SymbolEntrez IDGene Name
Hoxc5 ENSMUSG00000022485.3 Hoxc5
Lhx2 ENSMUSG00000000247.5 Lhx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Lhx2mm10_v2_chr2_+_38341068_38341092-0.165.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Lhx2_Hoxc5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_170009892 1.422 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chr12_+_116275386 1.205 ENSMUST00000090195.4
Gm11027
predicted gene 11027
chr5_-_106926245 1.123 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chrM_+_10167 1.030 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr4_-_155645408 0.924 ENSMUST00000115821.2
Gm10563
predicted gene 10563
chrY_+_90785442 0.817 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr4_-_14621805 0.776 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr12_-_87444017 0.754 ENSMUST00000091090.4
2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr7_-_5413145 0.753 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr13_+_44121167 0.738 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr1_+_170308802 0.686 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr5_-_62766153 0.678 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_+_17316078 0.662 ENSMUST00000105311.3
Gm6712
predicted gene 6712
chr2_-_180954620 0.662 ENSMUST00000139929.1
Nkain4
Na+/K+ transporting ATPase interacting 4
chr12_-_84617326 0.647 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr4_+_147132038 0.639 ENSMUST00000084149.3
Gm13139
predicted gene 13139
chrX_+_103356464 0.613 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr16_+_65520503 0.611 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
Pou1f1


POU domain, class 1, transcription factor 1


chr9_+_25089422 0.597 ENSMUST00000086238.2
Gm10181
predicted gene 10181
chrY_+_90784738 0.591 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr4_+_146610961 0.585 ENSMUST00000130825.1
Gm13248
predicted gene 13248
chr4_+_147492417 0.507 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chrX_+_170010744 0.497 ENSMUST00000178789.1
Gm21887
predicted gene, 21887
chr1_+_137966529 0.468 ENSMUST00000182158.1
A430106G13Rik
RIKEN cDNA A430106G13 gene
chr17_-_36032682 0.467 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr15_+_98571004 0.461 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr4_+_145510759 0.453 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225

chr3_-_85722474 0.447 ENSMUST00000119077.1
Fam160a1
family with sequence similarity 160, member A1
chr4_+_43493345 0.444 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr4_+_145585166 0.432 ENSMUST00000105739.1
ENSMUST00000119718.1
Gm13212

predicted gene 13212

chr16_+_18836573 0.423 ENSMUST00000055413.6
2510002D24Rik
RIKEN cDNA 2510002D24 gene
chr10_+_90071095 0.417 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chrM_-_14060 0.405 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr4_+_3938888 0.404 ENSMUST00000121110.1
ENSMUST00000108386.1
ENSMUST00000149544.1
Chchd7


coiled-coil-helix-coiled-coil-helix domain containing 7


chr18_+_37355271 0.404 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr4_-_147809788 0.381 ENSMUST00000105734.3
ENSMUST00000176201.1
Gm13157
Gm20707
predicted gene 13157
predicted gene 20707
chrM_+_7005 0.381 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr2_+_110597298 0.372 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr3_+_105973711 0.372 ENSMUST00000000573.2
Ovgp1
oviductal glycoprotein 1
chr10_-_56228636 0.370 ENSMUST00000099739.3
Tbc1d32
TBC1 domain family, member 32
chr13_+_67833235 0.367 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chrY_-_1245685 0.357 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr8_+_34054622 0.357 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr3_+_53845086 0.356 ENSMUST00000108014.1
Gm10985
predicted gene 10985
chr2_+_176711933 0.348 ENSMUST00000108983.2
Gm14305
predicted gene 14305
chrM_+_11734 0.326 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chrX_+_73483602 0.326 ENSMUST00000033741.8
ENSMUST00000169489.1
Bgn

biglycan

chr11_+_98026918 0.320 ENSMUST00000017548.6
Rpl19
ribosomal protein L19
chr17_+_26715644 0.318 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr3_-_113577743 0.315 ENSMUST00000067980.5
Amy1
amylase 1, salivary
chrX_+_101449078 0.309 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr9_+_72958785 0.307 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr4_+_3938904 0.307 ENSMUST00000120732.1
ENSMUST00000041122.4
ENSMUST00000121651.1
ENSMUST00000121210.1
ENSMUST00000119307.1
ENSMUST00000123769.1
Chchd7





coiled-coil-helix-coiled-coil-helix domain containing 7





chr4_-_14621669 0.305 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr8_-_106573461 0.303 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr5_-_84417359 0.298 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr17_+_66111605 0.287 ENSMUST00000116556.2
Wash
WAS protein family homolog
chr8_+_84689308 0.277 ENSMUST00000125370.3
ENSMUST00000175784.1
Trmt1

tRNA methyltransferase 1

chr18_+_49832622 0.271 ENSMUST00000180611.1
Dmxl1
Dmx-like 1
chr4_-_14621494 0.270 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr3_+_138374121 0.263 ENSMUST00000171054.1
Adh6-ps1
alcohol dehydrogenase 6 (class V), pseudogene 1
chr6_-_57535422 0.262 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr2_+_154548888 0.262 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr7_+_130774069 0.261 ENSMUST00000048453.5
Btbd16
BTB (POZ) domain containing 16
chr13_-_73678005 0.255 ENSMUST00000022105.7
ENSMUST00000109680.2
ENSMUST00000109679.2
Slc6a18


solute carrier family 6 (neurotransmitter transporter), member 18


chrX_-_134111852 0.253 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chrM_+_2743 0.249 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr17_+_66111529 0.247 ENSMUST00000072383.6
Wash
WAS protein family homolog
chr8_-_84662841 0.245 ENSMUST00000060427.4
Ier2
immediate early response 2
chr11_+_98026695 0.244 ENSMUST00000092425.4
Rpl19
ribosomal protein L19
chr6_+_134929118 0.244 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr10_+_93488766 0.244 ENSMUST00000129421.1
Hal
histidine ammonia lyase
chr10_-_33995054 0.242 ENSMUST00000164429.1
Gm17567
predicted gene, 17567
chr5_-_109691041 0.242 ENSMUST00000092720.3
5430403G16Rik
RIKEN cDNA 5430403G16 gene
chr8_+_84689247 0.241 ENSMUST00000109767.2
ENSMUST00000177084.1
ENSMUST00000109768.2
ENSMUST00000152301.2
ENSMUST00000177423.1
Trmt1




tRNA methyltransferase 1




chrX_+_20870166 0.241 ENSMUST00000115342.3
ENSMUST00000009530.4
Timp1

tissue inhibitor of metalloproteinase 1

chr2_+_162931520 0.239 ENSMUST00000130411.1
Srsf6
serine/arginine-rich splicing factor 6
chr10_-_18743691 0.235 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr8_-_70527945 0.232 ENSMUST00000138260.1
ENSMUST00000117580.1
Kxd1

KxDL motif containing 1

chr6_-_34977999 0.232 ENSMUST00000044387.7
2010107G12Rik
RIKEN cDNA 2010107G12 gene
chrM_+_3906 0.230 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr4_+_146654927 0.228 ENSMUST00000070932.3
Gm13248
predicted gene 13248
chr7_+_19508712 0.228 ENSMUST00000002112.8
ENSMUST00000108455.1
Trappc6a

trafficking protein particle complex 6A

chr2_+_131491764 0.227 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr13_+_23555023 0.227 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr2_+_65620829 0.227 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr6_-_136875794 0.226 ENSMUST00000032342.1
Mgp
matrix Gla protein
chrX_+_136741821 0.226 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chrX_-_73911229 0.225 ENSMUST00000114404.1
ENSMUST00000114407.2
ENSMUST00000114406.2
ENSMUST00000064376.6
ENSMUST00000114405.1
Arhgap4




Rho GTPase activating protein 4




chr18_+_61639542 0.218 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr2_-_86347764 0.216 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr2_-_73580288 0.215 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr2_+_119047116 0.214 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr7_-_19604444 0.213 ENSMUST00000086041.5
Clasrp
CLK4-associating serine/arginine rich protein
chr6_+_4003926 0.212 ENSMUST00000031670.8
Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr11_+_116843278 0.207 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr1_+_16688405 0.205 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr8_-_70510322 0.205 ENSMUST00000140679.1
ENSMUST00000129909.1
ENSMUST00000081940.4
Uba52


ubiquitin A-52 residue ribosomal protein fusion product 1


chr8_-_70897407 0.202 ENSMUST00000054220.8
Rpl18a
ribosomal protein L18A
chr2_+_36230426 0.202 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr4_+_95557494 0.202 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr10_-_76110956 0.201 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr3_+_63295815 0.197 ENSMUST00000029400.1
Mme
membrane metallo endopeptidase
chr3_+_107291215 0.196 ENSMUST00000029502.7
Slc16a4
solute carrier family 16 (monocarboxylic acid transporters), member 4
chr18_+_12741324 0.196 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr11_-_29515017 0.196 ENSMUST00000133103.1
ENSMUST00000039900.3
Prorsd1

prolyl-tRNA synthetase domain containing 1

chr6_+_116650674 0.196 ENSMUST00000067354.5
ENSMUST00000178241.1
8430408G22Rik

RIKEN cDNA 8430408G22 gene

chr2_+_91257323 0.195 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr9_+_118506226 0.195 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr18_+_37435602 0.195 ENSMUST00000055495.5
Pcdhb12
protocadherin beta 12
chr17_-_26095487 0.195 ENSMUST00000025007.5
Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr13_+_83732438 0.192 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chrM_+_9870 0.191 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr14_+_24490678 0.191 ENSMUST00000169826.1
ENSMUST00000112384.3
Rps24

ribosomal protein S24

chrX_-_7899196 0.190 ENSMUST00000115654.1
Pqbp1
polyglutamine binding protein 1
chr2_+_125068118 0.186 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr11_+_58917889 0.185 ENSMUST00000069941.6
Btnl10
butyrophilin-like 10
chr19_+_5088534 0.185 ENSMUST00000025811.4
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr10_-_14718191 0.183 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr10_-_86022325 0.183 ENSMUST00000181665.1
A230060F14Rik
RIKEN cDNA A230060F14 gene
chr4_+_147507600 0.180 ENSMUST00000063704.7
Gm13152
predicted gene 13152
chr3_+_103739366 0.178 ENSMUST00000106852.1
Gm10964
predicted gene 10964
chr10_-_18227473 0.178 ENSMUST00000174592.1
Ccdc28a
coiled-coil domain containing 28A
chr8_+_40354303 0.178 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr14_+_99298652 0.177 ENSMUST00000005279.6
Klf5
Kruppel-like factor 5
chr7_-_19399859 0.176 ENSMUST00000047170.3
ENSMUST00000108459.2
Klc3

kinesin light chain 3

chr4_+_32623985 0.175 ENSMUST00000108178.1
Casp8ap2
caspase 8 associated protein 2
chrX_+_16619698 0.175 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chr3_+_5218516 0.175 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr5_+_137641334 0.175 ENSMUST00000177466.1
ENSMUST00000166099.2
Sap25

sin3 associated polypeptide

chr10_+_80249441 0.174 ENSMUST00000020361.6
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr15_+_102326400 0.173 ENSMUST00000165717.1
Pfdn5
prefoldin 5
chr9_-_61914538 0.172 ENSMUST00000008036.7
Rplp1
ribosomal protein, large, P1
chr4_+_101986626 0.172 ENSMUST00000106914.1
Gm12789
predicted gene 12789
chr4_+_95967205 0.172 ENSMUST00000030306.7
Hook1
hook homolog 1 (Drosophila)
chr12_+_109545390 0.171 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr3_-_36053512 0.167 ENSMUST00000166644.2
ENSMUST00000062056.8
Ccdc144b

coiled-coil domain containing 144B

chr17_+_35089229 0.167 ENSMUST00000007251.7
Abhd16a
abhydrolase domain containing 16A
chr5_+_107497718 0.165 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr8_-_70527645 0.164 ENSMUST00000132867.1
Kxd1
KxDL motif containing 1
chr18_+_9958147 0.160 ENSMUST00000025137.7
Thoc1
THO complex 1
chr16_+_44867097 0.157 ENSMUST00000102805.3
Cd200r2
Cd200 receptor 2
chr8_+_66386292 0.156 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr6_-_101377342 0.156 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr17_-_46327990 0.156 ENSMUST00000167360.1
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr10_+_70204675 0.156 ENSMUST00000020090.1
2310015B20Rik
RIKEN cDNA 2310015B20 gene
chr7_-_27166732 0.153 ENSMUST00000080058.4
Egln2
EGL nine homolog 2 (C. elegans)
chr1_+_97770158 0.153 ENSMUST00000112844.3
ENSMUST00000112842.1
ENSMUST00000027571.6
Gin1


gypsy retrotransposon integrase 1


chr4_+_116596672 0.153 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chr11_-_115419917 0.153 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr4_-_155785864 0.152 ENSMUST00000097742.2
Tmem88b
transmembrane protein 88B
chr17_+_34931253 0.152 ENSMUST00000007253.5
Neu1
neuraminidase 1
chr1_-_184732616 0.151 ENSMUST00000048572.6
Hlx
H2.0-like homeobox
chr11_+_109543694 0.151 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr4_+_47208005 0.150 ENSMUST00000082303.6
ENSMUST00000102917.4
Col15a1

collagen, type XV, alpha 1

chr6_-_85762480 0.149 ENSMUST00000168531.1
Cml3
camello-like 3
chr1_-_24612700 0.148 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr10_-_81350191 0.147 ENSMUST00000122993.1
Hmg20b
high mobility group 20B
chr14_-_79868398 0.147 ENSMUST00000179430.1
Gm10845
predicted gene 10845
chr18_+_42511496 0.147 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr4_-_3938354 0.146 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr2_+_91256813 0.146 ENSMUST00000144394.1
ENSMUST00000028694.5
ENSMUST00000168916.1
ENSMUST00000156919.1
Pacsin3



protein kinase C and casein kinase substrate in neurons 3



chr11_+_94653767 0.144 ENSMUST00000025278.7
Mrpl27
mitochondrial ribosomal protein L27
chr14_+_26259109 0.142 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr6_-_28397999 0.142 ENSMUST00000035930.4
Zfp800
zinc finger protein 800
chr15_+_34453285 0.141 ENSMUST00000060894.7
BC030476
cDNA sequence BC030476
chr9_-_22117123 0.140 ENSMUST00000013966.6
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chrX_+_99042581 0.140 ENSMUST00000036606.7
Stard8
START domain containing 8
chr7_+_28392916 0.139 ENSMUST00000003529.8
Paf1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr10_-_81350389 0.138 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chrX_-_7899220 0.137 ENSMUST00000033497.2
Pqbp1
polyglutamine binding protein 1
chr7_+_6474088 0.137 ENSMUST00000056144.5
Olfr1346
olfactory receptor 1346
chr17_-_26099257 0.136 ENSMUST00000053575.3
Gm8186
predicted gene 8186
chr15_+_9436028 0.136 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr8_-_123236198 0.134 ENSMUST00000166768.1
ENSMUST00000098327.1
Spata2l

spermatogenesis associated 2-like

chr9_+_80165079 0.133 ENSMUST00000184480.1
Myo6
myosin VI
chr2_-_131160006 0.133 ENSMUST00000103188.3
ENSMUST00000133602.1
ENSMUST00000028800.5
1700037H04Rik


RIKEN cDNA 1700037H04 gene


chr3_-_116712644 0.132 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr5_+_90794530 0.132 ENSMUST00000031322.6
Cxcl15
chemokine (C-X-C motif) ligand 15
chr10_+_80141457 0.132 ENSMUST00000105367.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr14_-_69707493 0.131 ENSMUST00000121142.1
R3hcc1
R3H domain and coiled-coil containing 1
chr6_+_65042575 0.130 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr17_-_46327949 0.128 ENSMUST00000047970.7
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr1_+_46066738 0.125 ENSMUST00000069293.7
Dnah7b
dynein, axonemal, heavy chain 7B
chr14_+_56668242 0.125 ENSMUST00000116468.1
Mphosph8
M-phase phosphoprotein 8
chr18_+_12972225 0.123 ENSMUST00000025290.5
Impact
imprinted and ancient
chr10_-_81350305 0.123 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr10_-_128744014 0.123 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr10_+_29143996 0.123 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr4_-_147868631 0.122 ENSMUST00000030886.8
ENSMUST00000172710.1
Miip

migration and invasion inhibitory protein

chr17_-_48432723 0.122 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr4_+_52439235 0.121 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
Smc2


structural maintenance of chromosomes 2


chr1_+_58210397 0.121 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr10_+_80264942 0.121 ENSMUST00000105362.1
ENSMUST00000105361.3
Dazap1

DAZ associated protein 1

chr18_+_60774675 0.121 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chrX_+_9885622 0.121 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr8_+_70527829 0.121 ENSMUST00000119698.1
Fkbp8
FK506 binding protein 8
chr8_+_70527724 0.119 ENSMUST00000119353.2
ENSMUST00000075491.7
Fkbp8

FK506 binding protein 8

chr16_-_4880284 0.118 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr17_-_71460395 0.116 ENSMUST00000180522.1
Gm4707
predicted gene 4707

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.2 1.4 GO:0019532 oxalate transport(GO:0019532)
0.2 0.5 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 0.5 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.4 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 1.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.3 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.3 GO:0072592 regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592)
0.1 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.2 GO:0006547 histidine metabolic process(GO:0006547) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.2 GO:0048296 negative regulation of isotype switching(GO:0045829) isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.0 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.2 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.9 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0046549 retinal cone cell development(GO:0046549)
0.0 1.2 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.0 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0060768 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.0 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.6 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.1 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.0 0.1 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 3.0 GO:0070469 respiratory chain(GO:0070469)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.0 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004568 chitinase activity(GO:0004568)
0.1 1.4 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 0.3 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 2.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.2 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 1.2 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.0 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.4 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 1.3 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins