Motif ID: Maff

Z-value: 0.532


Transcription factors associated with Maff:

Gene SymbolEntrez IDGene Name
Maff ENSMUSG00000042622.7 Maff

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Maffmm10_v2_chr15_+_79347534_79347556-0.253.2e-01Click!


Activity profile for motif Maff.

activity profile for motif Maff


Sorted Z-values histogram for motif Maff

Sorted Z-values for motif Maff



Network of associatons between targets according to the STRING database.



First level regulatory network of Maff

PNG image of the network

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Top targets:


Showing 1 to 20 of 89 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_75308373 1.220 ENSMUST00000085164.5
 Sv2b
synaptic vesicle glycoprotein 2 b
chr2_-_84886692 0.752 ENSMUST00000054514.5
ENSMUST00000151799.1
 Rtn4rl2

reticulon 4 receptor-like 2

chr10_+_26078255 0.646 ENSMUST00000041011.3
 Gm9767
predicted gene 9767
chr7_-_64925560 0.602 ENSMUST00000149851.1
 Fam189a1
family with sequence similarity 189, member A1
chr18_+_60963517 0.552 ENSMUST00000115295.2
ENSMUST00000039904.6
 Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr19_+_58728887 0.490 ENSMUST00000048644.5
 Pnliprp1
pancreatic lipase related protein 1
chr9_-_111690313 0.488 ENSMUST00000035083.7
 Stac
src homology three (SH3) and cysteine rich domain
chr19_+_56722372 0.484 ENSMUST00000038949.4
 Adrb1
adrenergic receptor, beta 1
chr15_-_25413752 0.444 ENSMUST00000058845.7
 Basp1
brain abundant, membrane attached signal protein 1
chr3_+_127791374 0.394 ENSMUST00000171621.1
 Tifa
TRAF-interacting protein with forkhead-associated domain
chr7_-_44997535 0.386 ENSMUST00000124232.1
ENSMUST00000003290.4
 Bcl2l12

BCL2-like 12 (proline rich)

chr10_+_62920648 0.363 ENSMUST00000144459.1
 Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr13_+_48261427 0.362 ENSMUST00000021810.1
 Id4
inhibitor of DNA binding 4
chr4_+_94556546 0.359 ENSMUST00000094969.1
 Gm10306
predicted gene 10306
chr5_+_7179299 0.343 ENSMUST00000179460.1
 Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr11_-_119228461 0.341 ENSMUST00000036113.3
 Tbc1d16
TBC1 domain family, member 16
chr9_+_65460926 0.338 ENSMUST00000034955.6
 Spg21
spastic paraplegia 21 homolog (human)
chr4_-_143299498 0.306 ENSMUST00000030317.7
 Pdpn
podoplanin
chr2_-_69206133 0.299 ENSMUST00000112320.1
 Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_+_84528964 0.287 ENSMUST00000180387.1
 Gm2115
predicted gene 2115

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.6 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 0.5 GO:1900133 renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.1 0.5 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.1 0.4 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.4 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.4 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.1 0.2 GO:1990523 bone regeneration(GO:1990523)
0.1 0.2 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475) negative regulation of t-circle formation(GO:1904430)
0.1 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.1 GO:0002725 negative regulation of antigen processing and presentation(GO:0002578) negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 0.6 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.1 0.5 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0005827 equatorial microtubule organizing center(GO:0000923) polar microtubule(GO:0005827)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 0.5 GO:0051379 epinephrine binding(GO:0051379)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0070739 NEDD8 transferase activity(GO:0019788) protein-glutamic acid ligase activity(GO:0070739)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes