Motif ID: Mbd2

Z-value: 0.777


Transcription factors associated with Mbd2:

Gene SymbolEntrez IDGene Name
Mbd2 ENSMUSG00000024513.10 Mbd2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mbd2mm10_v2_chr18_+_70568189_70568398-0.391.1e-01Click!


Activity profile for motif Mbd2.

activity profile for motif Mbd2


Sorted Z-values histogram for motif Mbd2

Sorted Z-values for motif Mbd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Mbd2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_108003414 2.161 ENSMUST00000109887.1
ENSMUST00000109891.2
Bcl11b

B cell leukemia/lymphoma 11B

chr15_-_28025834 1.120 ENSMUST00000090247.5
Trio
triple functional domain (PTPRF interacting)
chr5_+_37028329 1.103 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr2_-_27475600 0.900 ENSMUST00000147736.1
Brd3
bromodomain containing 3
chr9_-_108190352 0.890 ENSMUST00000035208.7
Bsn
bassoon
chr5_+_36868467 0.888 ENSMUST00000031003.7
Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr12_-_79007276 0.887 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr16_+_20517000 0.885 ENSMUST00000171572.1
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr15_-_73645665 0.870 ENSMUST00000130765.1
Slc45a4
solute carrier family 45, member 4
chr9_-_51008936 0.822 ENSMUST00000176824.1
ENSMUST00000176663.1
ENSMUST00000041375.10
Sik2


salt inducible kinase 2


chr8_-_84800344 0.778 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr4_-_120747248 0.771 ENSMUST00000030376.7
Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr4_+_133039482 0.754 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr18_-_43393346 0.740 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr11_-_94474088 0.732 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr16_+_20516962 0.730 ENSMUST00000003318.5
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr6_-_126740151 0.715 ENSMUST00000112242.1
Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr14_+_25607797 0.704 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr11_+_104231573 0.688 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr4_-_148287927 0.664 ENSMUST00000047720.8
Ptchd2
patched domain containing 2
chr12_-_108003594 0.656 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr10_+_13966268 0.643 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr11_+_104231515 0.604 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chrX_+_152144240 0.603 ENSMUST00000168786.1
ENSMUST00000112605.1
ENSMUST00000112604.1
Iqsec2


IQ motif and Sec7 domain 2


chr6_+_30401866 0.601 ENSMUST00000068240.6
ENSMUST00000068259.6
Klhdc10

kelch domain containing 10

chr2_-_94406647 0.599 ENSMUST00000111237.2
ENSMUST00000094801.4
ENSMUST00000111238.1
Ttc17


tetratricopeptide repeat domain 17


chr11_+_104231465 0.591 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr14_-_24245913 0.586 ENSMUST00000073687.6
ENSMUST00000090398.4
Dlg5

discs, large homolog 5 (Drosophila)

chr12_-_99393010 0.583 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr2_+_35622160 0.579 ENSMUST00000112992.2
Dab2ip
disabled 2 interacting protein
chr11_+_57645417 0.568 ENSMUST00000066987.7
ENSMUST00000108846.1
Galnt10

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10

chr15_-_99457712 0.565 ENSMUST00000161948.1
Nckap5l
NCK-associated protein 5-like
chr13_+_110395041 0.564 ENSMUST00000022212.7
Plk2
polo-like kinase 2
chr19_+_56722372 0.559 ENSMUST00000038949.4
Adrb1
adrenergic receptor, beta 1
chr7_-_37770757 0.534 ENSMUST00000176680.1
Zfp536
zinc finger protein 536
chr3_-_103791075 0.529 ENSMUST00000106845.2
ENSMUST00000029438.8
ENSMUST00000121324.1
Hipk1


homeodomain interacting protein kinase 1


chr2_+_35622010 0.526 ENSMUST00000091010.5
Dab2ip
disabled 2 interacting protein
chr7_-_74013676 0.522 ENSMUST00000026896.4
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr4_+_149586555 0.508 ENSMUST00000039144.6
Clstn1
calsyntenin 1
chr13_+_46418266 0.496 ENSMUST00000037923.3
Rbm24
RNA binding motif protein 24
chr11_+_7063423 0.476 ENSMUST00000020706.4
Adcy1
adenylate cyclase 1
chr17_+_65782573 0.475 ENSMUST00000161324.1
ENSMUST00000161127.1
Ppp4r1

protein phosphatase 4, regulatory subunit 1

chr12_+_3806513 0.472 ENSMUST00000172719.1
Dnmt3a
DNA methyltransferase 3A
chr6_+_4747306 0.465 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10


paternally expressed 10


chr5_+_146384947 0.458 ENSMUST00000110600.1
ENSMUST00000016143.7
Wasf3

WAS protein family, member 3

chr7_+_67952817 0.457 ENSMUST00000005671.8
Igf1r
insulin-like growth factor I receptor
chr9_-_106789130 0.456 ENSMUST00000046502.5
Rad54l2
RAD54 like 2 (S. cerevisiae)
chr2_-_24763047 0.452 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr10_+_127380799 0.452 ENSMUST00000111628.2
R3hdm2
R3H domain containing 2
chr1_+_89454769 0.451 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr12_-_85339346 0.451 ENSMUST00000040992.7
Nek9
NIMA (never in mitosis gene a)-related expressed kinase 9
chr19_-_47464406 0.444 ENSMUST00000111800.2
ENSMUST00000081619.2
Sh3pxd2a

SH3 and PX domains 2A

chr19_+_6241668 0.419 ENSMUST00000045351.6
Atg2a
autophagy related 2A
chr19_-_5688908 0.418 ENSMUST00000113615.2
Pcnxl3
pecanex-like 3 (Drosophila)
chr5_-_36530610 0.412 ENSMUST00000171385.1
Tbc1d14
TBC1 domain family, member 14
chr6_-_149101506 0.403 ENSMUST00000127727.1
Dennd5b
DENN/MADD domain containing 5B
chr13_-_52981027 0.400 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr2_+_30982350 0.399 ENSMUST00000061544.4
ENSMUST00000138161.1
ENSMUST00000142232.1
Usp20


ubiquitin specific peptidase 20


chr11_-_106920359 0.398 ENSMUST00000167787.1
ENSMUST00000092517.2
Smurf2

SMAD specific E3 ubiquitin protein ligase 2

chr11_-_97573929 0.394 ENSMUST00000126287.1
ENSMUST00000107590.1
Srcin1

SRC kinase signaling inhibitor 1

chr12_-_102878406 0.392 ENSMUST00000045652.6
Btbd7
BTB (POZ) domain containing 7
chr7_-_130266191 0.388 ENSMUST00000122054.1
Fgfr2
fibroblast growth factor receptor 2
chrX_-_160994665 0.387 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chr1_+_74601441 0.385 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
Stk36


serine/threonine kinase 36


chr14_-_55116935 0.377 ENSMUST00000022819.5
Jph4
junctophilin 4
chrX_+_151047170 0.368 ENSMUST00000026296.7
Fgd1
FYVE, RhoGEF and PH domain containing 1
chr9_-_24503127 0.368 ENSMUST00000142064.1
ENSMUST00000170356.1
Dpy19l1

dpy-19-like 1 (C. elegans)

chr5_+_118169712 0.363 ENSMUST00000054836.6
Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr11_-_61267177 0.360 ENSMUST00000066277.3
ENSMUST00000074127.7
ENSMUST00000108715.2
Aldh3a2


aldehyde dehydrogenase family 3, subfamily A2


chrX_+_151521146 0.355 ENSMUST00000112670.1
ENSMUST00000046962.4
ENSMUST00000112668.2
ENSMUST00000046950.6
Phf8



PHD finger protein 8



chr5_+_123394782 0.352 ENSMUST00000111596.1
ENSMUST00000068237.5
Mlxip

MLX interacting protein

chr12_+_81859964 0.349 ENSMUST00000021567.5
Pcnx
pecanex homolog (Drosophila)
chr7_-_126082406 0.347 ENSMUST00000073935.5
Gsg1l
GSG1-like
chr16_+_20517076 0.342 ENSMUST00000171774.1
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr11_-_97574040 0.338 ENSMUST00000107593.1
Srcin1
SRC kinase signaling inhibitor 1
chr10_-_78352469 0.333 ENSMUST00000138035.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr11_-_87086752 0.332 ENSMUST00000020801.7
Smg8
smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr11_-_98018308 0.328 ENSMUST00000107561.2
Cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr1_+_191718389 0.326 ENSMUST00000110856.1
ENSMUST00000130876.1
Lpgat1

lysophosphatidylglycerol acyltransferase 1

chr3_+_95658771 0.326 ENSMUST00000178686.1
Mcl1
myeloid cell leukemia sequence 1
chr5_+_114568016 0.323 ENSMUST00000043650.7
Fam222a
family with sequence similarity 222, member A
chr1_+_75375271 0.323 ENSMUST00000087122.5
Speg
SPEG complex locus
chr2_+_152293828 0.319 ENSMUST00000028963.7
ENSMUST00000144252.1
Tbc1d20

TBC1 domain family, member 20

chr9_+_26733845 0.319 ENSMUST00000115269.2
B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr4_-_149774238 0.317 ENSMUST00000105686.2
Slc25a33
solute carrier family 25, member 33
chr7_-_65156416 0.317 ENSMUST00000148459.1
ENSMUST00000119118.1
Fam189a1

family with sequence similarity 189, member A1

chrX_+_151520655 0.317 ENSMUST00000112666.1
ENSMUST00000168501.1
ENSMUST00000112662.2
Phf8


PHD finger protein 8


chr11_-_96829959 0.316 ENSMUST00000081775.5
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr15_+_80234071 0.315 ENSMUST00000023048.4
ENSMUST00000166030.1
Mief1

mitochondrial elongation factor 1

chr1_+_74601548 0.310 ENSMUST00000087186.4
Stk36
serine/threonine kinase 36
chr3_+_98382538 0.309 ENSMUST00000178372.1
Zfp697
zinc finger protein 697
chr11_+_32642706 0.306 ENSMUST00000109366.1
Fbxw11
F-box and WD-40 domain protein 11
chr5_-_115272883 0.306 ENSMUST00000040555.8
ENSMUST00000112096.2
ENSMUST00000112097.1
Rnf10


ring finger protein 10


chr4_+_43669266 0.303 ENSMUST00000107864.1
Tmem8b
transmembrane protein 8B
chr16_-_37539781 0.300 ENSMUST00000023525.8
Gtf2e1
general transcription factor II E, polypeptide 1 (alpha subunit)
chr2_+_158409842 0.300 ENSMUST00000109486.2
ENSMUST00000046274.5
Ralgapb

Ral GTPase activating protein, beta subunit (non-catalytic)

chr11_-_96829904 0.296 ENSMUST00000107657.1
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr11_+_69901816 0.292 ENSMUST00000177138.1
ENSMUST00000108617.3
ENSMUST00000177476.1
ENSMUST00000061837.4
Neurl4



neuralized homolog 4 (Drosophila)



chr11_-_75796048 0.291 ENSMUST00000021209.7
Doc2b
double C2, beta
chr11_-_35980473 0.291 ENSMUST00000018993.6
Wwc1
WW, C2 and coiled-coil domain containing 1
chr15_+_27466647 0.290 ENSMUST00000022875.6
Ank
progressive ankylosis
chr1_-_156035891 0.289 ENSMUST00000126448.1
Tor1aip1
torsin A interacting protein 1
chr12_-_102704896 0.288 ENSMUST00000178697.1
ENSMUST00000046518.5
Itpk1

inositol 1,3,4-triphosphate 5/6 kinase

chr13_-_34345174 0.284 ENSMUST00000040336.5
Slc22a23
solute carrier family 22, member 23
chr5_-_39644597 0.284 ENSMUST00000152057.1
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr7_-_27228605 0.283 ENSMUST00000003850.7
Itpkc
inositol 1,4,5-trisphosphate 3-kinase C
chr4_+_44756609 0.281 ENSMUST00000143385.1
Zcchc7
zinc finger, CCHC domain containing 7
chr11_+_32642826 0.280 ENSMUST00000093205.6
ENSMUST00000076383.7
Fbxw11

F-box and WD-40 domain protein 11

chr2_+_28192971 0.275 ENSMUST00000113920.1
Olfm1
olfactomedin 1
chr11_+_104231390 0.275 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr14_+_20707548 0.274 ENSMUST00000022358.7
Zswim8
zinc finger SWIM-type containing 8
chr7_+_100706623 0.274 ENSMUST00000107042.1
Fam168a
family with sequence similarity 168, member A
chr9_+_121719403 0.272 ENSMUST00000182225.1
Nktr
natural killer tumor recognition sequence
chr8_+_116943387 0.271 ENSMUST00000109099.3
Atmin
ATM interactor
chr10_-_78352212 0.269 ENSMUST00000146899.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr7_+_99381495 0.268 ENSMUST00000037528.8
Gdpd5
glycerophosphodiester phosphodiesterase domain containing 5
chr14_-_68124836 0.267 ENSMUST00000111089.1
ENSMUST00000022638.5
Nefm

neurofilament, medium polypeptide

chr11_+_69765970 0.265 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr2_-_167492826 0.264 ENSMUST00000109211.2
ENSMUST00000057627.9
Spata2

spermatogenesis associated 2

chr11_+_121259983 0.264 ENSMUST00000106113.1
Foxk2
forkhead box K2
chr14_+_121035538 0.261 ENSMUST00000026635.7
Farp1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr9_+_108692116 0.261 ENSMUST00000035220.6
Prkar2a
protein kinase, cAMP dependent regulatory, type II alpha
chr4_-_155345696 0.259 ENSMUST00000103178.4
Prkcz
protein kinase C, zeta
chr17_-_45549655 0.259 ENSMUST00000180252.1
Tmem151b
transmembrane protein 151B
chr4_+_43669610 0.255 ENSMUST00000107866.1
Tmem8b
transmembrane protein 8B
chr11_+_69765899 0.254 ENSMUST00000108640.1
ENSMUST00000108639.1
Zbtb4

zinc finger and BTB domain containing 4

chr8_+_85036906 0.253 ENSMUST00000093360.4
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr4_-_126753372 0.250 ENSMUST00000030637.7
ENSMUST00000106116.1
Ncdn

neurochondrin

chr10_+_127380591 0.249 ENSMUST00000166820.1
R3hdm2
R3H domain containing 2
chr7_+_25282784 0.248 ENSMUST00000165239.1
Cic
capicua homolog (Drosophila)
chr19_+_10041548 0.246 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chr4_+_43957401 0.242 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chr1_-_36558214 0.242 ENSMUST00000154493.1
Sema4c
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr2_-_120563795 0.241 ENSMUST00000055241.6
ENSMUST00000135625.1
Zfp106

zinc finger protein 106

chr12_-_27342696 0.237 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr12_-_72408934 0.232 ENSMUST00000078505.7
Rtn1
reticulon 1
chr15_-_98871175 0.231 ENSMUST00000178486.2
ENSMUST00000023741.9
Kmt2d

lysine (K)-specific methyltransferase 2D

chr2_-_130629994 0.230 ENSMUST00000028761.4
ENSMUST00000110262.1
Ubox5
Fastkd5
U box domain containing 5
FAST kinase domains 5
chr2_+_32395896 0.230 ENSMUST00000028162.3
Ptges2
prostaglandin E synthase 2
chr6_-_124756478 0.229 ENSMUST00000088357.5
Atn1
atrophin 1
chr8_+_85037151 0.225 ENSMUST00000166592.1
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr4_+_149586432 0.222 ENSMUST00000105691.1
Clstn1
calsyntenin 1
chr7_+_19176416 0.219 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr9_-_62811592 0.219 ENSMUST00000034775.8
Fem1b
feminization 1 homolog b (C. elegans)
chr4_+_53440516 0.218 ENSMUST00000107651.2
ENSMUST00000107647.1
Slc44a1

solute carrier family 44, member 1

chr7_+_126272589 0.218 ENSMUST00000056028.9
Sbk1
SH3-binding kinase 1
chr2_-_35979624 0.216 ENSMUST00000028248.4
ENSMUST00000112976.2
Ttll11

tubulin tyrosine ligase-like family, member 11

chr4_+_115737738 0.216 ENSMUST00000106525.2
Efcab14
EF-hand calcium binding domain 14
chr16_-_4213404 0.214 ENSMUST00000023165.6
Crebbp
CREB binding protein
chr7_-_19665005 0.214 ENSMUST00000055242.9
Clptm1
cleft lip and palate associated transmembrane protein 1
chr17_+_8801742 0.212 ENSMUST00000089085.2
Pde10a
phosphodiesterase 10A
chr4_+_115737754 0.212 ENSMUST00000106522.2
Efcab14
EF-hand calcium binding domain 14
chr1_+_74854954 0.212 ENSMUST00000160379.2
Cdk5r2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr12_-_108275409 0.211 ENSMUST00000136175.1
Ccdc85c
coiled-coil domain containing 85C
chr10_-_118868903 0.209 ENSMUST00000004281.8
Dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr1_+_135146782 0.208 ENSMUST00000027684.4
Arl8a
ADP-ribosylation factor-like 8A
chr11_+_53350783 0.208 ENSMUST00000060945.5
Aff4
AF4/FMR2 family, member 4
chr1_+_74506044 0.208 ENSMUST00000087215.5
Rqcd1
rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr12_+_101975965 0.208 ENSMUST00000047357.8
Cpsf2
cleavage and polyadenylation specific factor 2
chr7_-_66689474 0.208 ENSMUST00000068980.3
Asb7
ankyrin repeat and SOCS box-containing 7
chr2_-_166996098 0.207 ENSMUST00000049412.5
Stau1
staufen (RNA binding protein) homolog 1 (Drosophila)
chr18_+_25168993 0.205 ENSMUST00000036619.7
ENSMUST00000165400.1
ENSMUST00000097643.3
AW554918


expressed sequence AW554918


chr2_-_166996259 0.204 ENSMUST00000109238.2
ENSMUST00000109235.1
ENSMUST00000109236.2
Stau1


staufen (RNA binding protein) homolog 1 (Drosophila)


chr11_+_94990996 0.198 ENSMUST00000038696.5
Ppp1r9b
protein phosphatase 1, regulatory subunit 9B
chr3_+_98382438 0.194 ENSMUST00000056096.8
Zfp697
zinc finger protein 697
chr5_+_118560719 0.194 ENSMUST00000100816.4
Med13l
mediator complex subunit 13-like
chr2_+_28193093 0.193 ENSMUST00000100244.3
Olfm1
olfactomedin 1
chr15_-_99457742 0.191 ENSMUST00000023747.7
Nckap5l
NCK-associated protein 5-like
chr7_+_29303938 0.186 ENSMUST00000108231.1
Dpf1
D4, zinc and double PHD fingers family 1
chr2_-_132145057 0.185 ENSMUST00000028815.8
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr11_-_102447647 0.184 ENSMUST00000049057.4
Fam171a2
family with sequence similarity 171, member A2
chr15_-_73184840 0.183 ENSMUST00000044113.10
Ago2
argonaute RISC catalytic subunit 2
chr1_+_172341197 0.183 ENSMUST00000056136.3
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr2_-_180273488 0.181 ENSMUST00000108891.1
Cables2
CDK5 and Abl enzyme substrate 2
chr4_-_151861667 0.180 ENSMUST00000169423.2
Camta1
calmodulin binding transcription activator 1
chr18_-_13972617 0.178 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr7_+_141949846 0.178 ENSMUST00000172652.1
Brsk2
BR serine/threonine kinase 2
chr4_-_130574150 0.177 ENSMUST00000105993.3
Nkain1
Na+/K+ transporting ATPase interacting 1
chr9_+_30427329 0.176 ENSMUST00000164099.1
Snx19
sorting nexin 19
chr7_-_130266237 0.175 ENSMUST00000117872.1
ENSMUST00000120187.1
Fgfr2

fibroblast growth factor receptor 2

chr10_-_78352323 0.174 ENSMUST00000001240.5
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chrX_-_12762069 0.171 ENSMUST00000096495.4
ENSMUST00000076016.5
Med14

mediator complex subunit 14

chr10_-_80742211 0.171 ENSMUST00000020420.7
Ap3d1
adaptor-related protein complex 3, delta 1 subunit
chr1_-_156718894 0.169 ENSMUST00000086153.6
Fam20b
family with sequence similarity 20, member B
chr4_+_106911517 0.168 ENSMUST00000072753.6
ENSMUST00000097934.3
Ssbp3

single-stranded DNA binding protein 3

chr9_+_61373608 0.167 ENSMUST00000161689.1
Tle3
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr5_-_66618752 0.166 ENSMUST00000162366.1
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr8_-_90348126 0.163 ENSMUST00000176034.1
ENSMUST00000176616.1
Tox3

TOX high mobility group box family member 3

chr4_-_133339238 0.163 ENSMUST00000105906.1
Wdtc1
WD and tetratricopeptide repeats 1
chr1_-_177258182 0.163 ENSMUST00000111159.1
Akt3
thymoma viral proto-oncogene 3
chr9_-_44320229 0.163 ENSMUST00000065080.8
C2cd2l
C2 calcium-dependent domain containing 2-like
chr15_+_78913916 0.162 ENSMUST00000089378.4
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr11_-_120990871 0.162 ENSMUST00000154483.1
Csnk1d
casein kinase 1, delta
chr4_-_133339283 0.161 ENSMUST00000043305.7
Wdtc1
WD and tetratricopeptide repeats 1
chr6_-_4747019 0.159 ENSMUST00000126151.1
ENSMUST00000133306.1
ENSMUST00000123907.1
Sgce


sarcoglycan, epsilon


chr9_+_95559817 0.159 ENSMUST00000079597.5
Paqr9
progestin and adipoQ receptor family member IX
chr5_-_39644634 0.157 ENSMUST00000053116.6
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr3_-_90509450 0.157 ENSMUST00000107343.1
ENSMUST00000001043.7
ENSMUST00000107344.1
ENSMUST00000076639.4
ENSMUST00000107346.1
ENSMUST00000146740.1
ENSMUST00000107342.1
ENSMUST00000049937.6
Chtop







chromatin target of PRMT1







chr2_+_157914618 0.156 ENSMUST00000109523.1
Vstm2l
V-set and transmembrane domain containing 2-like
chr18_+_69346143 0.156 ENSMUST00000114980.1
Tcf4
transcription factor 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.3 2.0 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.3 0.9 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.3 0.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2 2.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.2 0.7 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 1.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.2 0.8 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.2 0.6 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.2 0.6 GO:1900133 renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.2 0.7 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2 0.7 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.4 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.5 GO:0044849 estrous cycle(GO:0044849) cholangiocyte apoptotic process(GO:1902488) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.6 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.3 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.4 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.3 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.2 GO:0060023 soft palate development(GO:0060023)
0.1 0.4 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.1 0.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003) cellular response to isoquinoline alkaloid(GO:0071317) regulation of opioid receptor signaling pathway(GO:2000474)
0.1 0.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.3 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.2 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.2 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.6 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 0.2 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.1 0.2 GO:0021586 pons maturation(GO:0021586)
0.1 0.3 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.1 0.4 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.5 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) trachea cartilage morphogenesis(GO:0060535) chemoattraction of axon(GO:0061642)
0.0 0.2 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.0 0.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.1 GO:0036509 trimming of terminal mannose on B branch(GO:0036509)
0.0 0.1 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.5 GO:0033574 response to testosterone(GO:0033574)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0061344 regulation of cell adhesion involved in heart morphogenesis(GO:0061344) positive regulation of ephrin receptor signaling pathway(GO:1901189)
0.0 0.4 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.5 GO:0044804 nucleophagy(GO:0044804)
0.0 0.2 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.2 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.0 0.1 GO:2001025 positive regulation of response to drug(GO:2001025)
0.0 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.0 0.3 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.8 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:1905072 detection of oxygen(GO:0003032) cell migration involved in endocardial cushion formation(GO:0003273) negative regulation of protein autophosphorylation(GO:0031953) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) cardiac jelly development(GO:1905072)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.2 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.3 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.0 0.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 1.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.3 1.1 GO:1990032 parallel fiber(GO:1990032)
0.2 2.2 GO:0045298 tubulin complex(GO:0045298)
0.2 1.9 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.2 GO:0098830 presynaptic endosome(GO:0098830)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.0 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.3 0.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.7 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 0.6 GO:0051379 epinephrine binding(GO:0051379)
0.2 0.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.3 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.5 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.6 GO:0043559 insulin binding(GO:0043559)
0.1 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.4 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.9 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 2.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.3 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.0 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.9 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.3 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.8 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.1 PID_NETRIN_PATHWAY Netrin-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.6 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.6 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.1 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.1 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex