Motif ID: Meox1

Z-value: 0.660


Transcription factors associated with Meox1:

Gene SymbolEntrez IDGene Name
Meox1 ENSMUSG00000001493.9 Meox1



Activity profile for motif Meox1.

activity profile for motif Meox1


Sorted Z-values histogram for motif Meox1

Sorted Z-values for motif Meox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox1

PNG image of the network

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Top targets:


Showing 1 to 20 of 131 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_98053415 2.386 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr9_+_123366921 2.068 ENSMUST00000038863.7
 Lars2
leucyl-tRNA synthetase, mitochondrial
chr5_-_62766153 1.894 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_+_92597104 1.679 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr8_+_66386292 1.580 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr5_+_107403496 1.362 ENSMUST00000049146.5
 Ephx4
epoxide hydrolase 4
chr7_+_103550368 1.311 ENSMUST00000106888.1
 Olfr613
olfactory receptor 613
chr14_+_27238018 1.210 ENSMUST00000049206.5
 Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr15_-_8710409 1.166 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_113577743 1.141 ENSMUST00000067980.5
 Amy1
amylase 1, salivary
chr4_-_14621805 1.100 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr10_+_81718919 1.055 ENSMUST00000085664.5
 Zfp433
RIKEN cDNA 1700123A16 gene
chr9_-_55919605 1.038 ENSMUST00000037408.8
 Scaper
S phase cyclin A-associated protein in the ER
chr15_-_8710734 0.977 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_+_18818895 0.875 ENSMUST00000166873.2
 Cdh10
cadherin 10
chr7_-_140154712 0.806 ENSMUST00000059241.7
 Sprn
shadow of prion protein
chr9_-_95750335 0.804 ENSMUST00000053785.3
 Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr1_-_134955847 0.785 ENSMUST00000168381.1
 Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chrX_+_136822781 0.774 ENSMUST00000113085.1
 Plp1
proteolipid protein (myelin) 1
chr15_-_37458523 0.765 ENSMUST00000116445.2
 Ncald
neurocalcin delta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 2.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 1.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 1.5 GO:0019532 oxalate transport(GO:0019532)
0.1 1.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 1.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 1.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 1.3 GO:0007608 sensory perception of smell(GO:0007608)
0.1 1.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.9 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.8 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.8 GO:0046541 saliva secretion(GO:0046541)
0.2 0.7 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.7 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.1 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 0.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.6 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.6 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.5 GO:0031672 A band(GO:0031672)
0.2 1.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.8 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640) sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.3 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.4 2.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 2.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 1.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.5 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.2 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4 1.1 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.7 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.2 0.5 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 0.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 0.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 0.5 GO:0004962 endothelin receptor activity(GO:0004962)

Gene overrepresentation in C2:CP category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.6 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.4 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.0 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.4 PID_EPHA_FWDPATHWAY EPHA forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.2 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.1 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions