Motif ID: Meox2

Z-value: 1.019


Transcription factors associated with Meox2:

Gene SymbolEntrez IDGene Name
Meox2 ENSMUSG00000036144.5 Meox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meox2mm10_v2_chr12_+_37108533_371085460.474.8e-02Click!


Activity profile for motif Meox2.

activity profile for motif Meox2


Sorted Z-values histogram for motif Meox2

Sorted Z-values for motif Meox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox2

PNG image of the network

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Top targets:


Showing 1 to 20 of 150 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_25980039 4.585 ENSMUST00000173155.1
 Duxbl1
double homeobox B-like 1
chr14_+_26119811 4.371 ENSMUST00000173617.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_26259109 3.201 ENSMUST00000174494.1
 Duxbl3
double homeobox B-like 3
chr14_+_25979401 2.061 ENSMUST00000173580.1
 Duxbl1
double homeobox B-like 1
chr8_-_46294592 1.793 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr16_+_42907563 1.557 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr14_+_26119173 1.514 ENSMUST00000174564.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_26258786 1.514 ENSMUST00000172517.1
 Duxbl3
double homeobox B-like 3
chr16_+_65520503 1.345 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
 Pou1f1


POU domain, class 1, transcription factor 1


chr7_-_5413145 1.190 ENSMUST00000108569.2
 Vmn1r58
vomeronasal 1 receptor 58
chr10_-_88683021 1.138 ENSMUST00000004473.8
 Spic
Spi-C transcription factor (Spi-1/PU.1 related)
chr3_+_107291215 1.134 ENSMUST00000029502.7
 Slc16a4
solute carrier family 16 (monocarboxylic acid transporters), member 4
chr3_+_53845086 1.050 ENSMUST00000108014.1
 Gm10985
predicted gene 10985
chr7_+_27927592 1.038 ENSMUST00000181644.1
 Gm26891
predicted gene, 26891
chr17_-_10320229 0.953 ENSMUST00000053066.6
 Qk
quaking
chr16_+_44943737 0.927 ENSMUST00000114622.3
ENSMUST00000166731.1
 Cd200r3

CD200 receptor 3

chr2_+_120629113 0.891 ENSMUST00000150912.1
ENSMUST00000180041.1
 Stard9

START domain containing 9

chr10_-_116972609 0.840 ENSMUST00000092165.4
 Gm10271
predicted gene 10271
chr16_-_57292845 0.803 ENSMUST00000023434.8
ENSMUST00000120112.1
ENSMUST00000119407.1
 Tmem30c


transmembrane protein 30C


chr9_+_21927471 0.803 ENSMUST00000170304.1
ENSMUST00000006403.6
 Ccdc159

coiled-coil domain containing 159


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.7 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 1.8 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 1.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 1.3 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 1.1 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 1.0 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.7 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.2 0.6 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.6 GO:0007128 meiotic prophase I(GO:0007128) prophase(GO:0051324)
0.0 0.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.4 GO:0051775 response to redox state(GO:0051775)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0006953 acute-phase response(GO:0006953)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.3 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.3 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.5 GO:0000150 recombinase activity(GO:0000150)
0.1 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.2 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.0 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors