Motif ID: Mga

Z-value: 0.302


Transcription factors associated with Mga:

Gene SymbolEntrez IDGene Name
Mga ENSMUSG00000033943.9 Mga

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mgamm10_v2_chr2_+_119897212_1198973050.455.8e-02Click!


Activity profile for motif Mga.

activity profile for motif Mga


Sorted Z-values histogram for motif Mga

Sorted Z-values for motif Mga



Network of associatons between targets according to the STRING database.



First level regulatory network of Mga

PNG image of the network

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Top targets:


Showing 1 to 20 of 65 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66801577 1.742 ENSMUST00000168589.1
Sla
src-like adaptor
chr15_-_43869993 0.742 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr10_+_81575257 0.606 ENSMUST00000135211.1
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr10_+_81575306 0.603 ENSMUST00000146916.1
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr13_+_29016267 0.563 ENSMUST00000140415.1
A330102I10Rik
RIKEN cDNA A330102I10 gene
chr11_+_49203465 0.447 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
Zfp62


zinc finger protein 62


chr2_+_85136355 0.423 ENSMUST00000057019.7
Aplnr
apelin receptor
chr11_+_49203285 0.420 ENSMUST00000109198.1
ENSMUST00000137061.2
Zfp62

zinc finger protein 62

chr5_-_138619751 0.354 ENSMUST00000085852.4
ENSMUST00000110905.2
Zfp68

zinc finger protein 68

chr3_+_13946368 0.340 ENSMUST00000171075.1
ENSMUST00000108372.2
Ralyl

RALY RNA binding protein-like

chr5_-_138619702 0.320 ENSMUST00000063262.4
Zfp68
zinc finger protein 68
chr5_-_138619653 0.319 ENSMUST00000129832.1
Zfp68
zinc finger protein 68
chrX_+_163909132 0.311 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr8_+_12984246 0.289 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chr4_+_43381979 0.248 ENSMUST00000035645.5
ENSMUST00000144911.1
Rusc2

RUN and SH3 domain containing 2

chr9_+_57940104 0.246 ENSMUST00000043059.7
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr6_-_41636389 0.238 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr14_-_52279238 0.227 ENSMUST00000167116.1
ENSMUST00000100631.4
Rab2b

RAB2B, member RAS oncogene family

chr17_-_32350569 0.219 ENSMUST00000050214.7
Akap8l
A kinase (PRKA) anchor protein 8-like
chr10_+_115384951 0.219 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.4 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.2 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)

Gene overrepresentation in cellular_component category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)

Gene overrepresentation in molecular_function category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway