Motif ID: Mnt

Z-value: 0.812


Transcription factors associated with Mnt:

Gene SymbolEntrez IDGene Name
Mnt ENSMUSG00000000282.6 Mnt

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mntmm10_v2_chr11_+_74830920_748310050.701.1e-03Click!


Activity profile for motif Mnt.

activity profile for motif Mnt


Sorted Z-values histogram for motif Mnt

Sorted Z-values for motif Mnt



Network of associatons between targets according to the STRING database.



First level regulatory network of Mnt

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_121495678 3.834 ENSMUST00000035120.4
 Cck
cholecystokinin
chr2_+_4300462 3.084 ENSMUST00000175669.1
 Frmd4a
FERM domain containing 4A
chr11_+_69095217 3.076 ENSMUST00000101004.2
 Per1
period circadian clock 1
chr17_-_66077022 2.809 ENSMUST00000150766.1
ENSMUST00000038116.5
 Ankrd12

ankyrin repeat domain 12

chr5_-_136170634 2.468 ENSMUST00000041048.1
 Orai2
ORAI calcium release-activated calcium modulator 2
chr15_+_81811414 2.414 ENSMUST00000023024.7
 Tef
thyrotroph embryonic factor
chr4_+_32657107 2.412 ENSMUST00000071642.4
ENSMUST00000178134.1
 Mdn1

midasin homolog (yeast)

chr7_-_68749170 2.404 ENSMUST00000118110.1
ENSMUST00000048068.7
 Arrdc4

arrestin domain containing 4

chr12_-_90738438 2.398 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr17_-_25570678 2.337 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chrX_-_51681703 2.116 ENSMUST00000088172.5
 Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr4_-_53159885 2.071 ENSMUST00000030010.3
 Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr3_-_89773221 2.057 ENSMUST00000038450.1
 4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr8_-_29219338 2.051 ENSMUST00000168630.2
 Unc5d
unc-5 homolog D (C. elegans)
chr2_-_130424242 2.051 ENSMUST00000089581.4
 Pced1a
PC-esterase domain containing 1A
chr12_+_24651346 1.985 ENSMUST00000020982.5
 Klf11
Kruppel-like factor 11
chr3_-_108086590 1.978 ENSMUST00000102638.1
ENSMUST00000102637.1
 Ampd2

adenosine monophosphate deaminase 2

chr14_-_78536762 1.929 ENSMUST00000123853.1
 Akap11
A kinase (PRKA) anchor protein 11
chr11_-_101785252 1.843 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr4_-_148038769 1.824 ENSMUST00000030879.5
ENSMUST00000137724.1
 Clcn6

chloride channel 6


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 245 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 4.7 GO:0008643 carbohydrate transport(GO:0008643)
0.1 3.9 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.4 3.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 3.4 GO:0097352 autophagosome maturation(GO:0097352)
0.6 3.3 GO:0055091 phospholipid homeostasis(GO:0055091)
1.1 3.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.6 3.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 2.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 2.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.9 2.8 GO:0043379 memory T cell differentiation(GO:0043379)
0.1 2.7 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.9 2.6 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.2 2.5 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 2.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.5 2.4 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.8 2.3 GO:0072034 renal vesicle induction(GO:0072034)
0.3 2.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 2.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 2.2 GO:0010771 negative regulation of cell morphogenesis involved in differentiation(GO:0010771)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 106 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 5.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 4.3 GO:0097060 synaptic membrane(GO:0097060)
0.3 3.8 GO:0043203 axon hillock(GO:0043203)
0.0 3.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 3.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.6 3.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 3.1 GO:0030426 growth cone(GO:0030426)
0.4 2.5 GO:0033263 CORVET complex(GO:0033263)
0.2 2.5 GO:1990635 proximal dendrite(GO:1990635)
0.0 2.3 GO:0030139 endocytic vesicle(GO:0030139)
0.1 2.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.1 GO:0005770 late endosome(GO:0005770)
0.2 2.0 GO:0070852 cell body fiber(GO:0070852)
0.1 1.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.6 1.8 GO:0000802 transverse filament(GO:0000802)
0.2 1.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 1.8 GO:0071141 SMAD protein complex(GO:0071141)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 176 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 4.8 GO:0051018 protein kinase A binding(GO:0051018)
0.2 4.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 4.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 3.9 GO:0015485 cholesterol binding(GO:0015485)
0.4 3.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 3.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 2.7 GO:0008017 microtubule binding(GO:0008017)
0.2 2.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 2.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.6 2.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.4 2.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 2.2 GO:0070888 E-box binding(GO:0070888)
0.7 2.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.5 2.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.3 2.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 1.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.8 PID_LKB1_PATHWAY LKB1 signaling events
0.0 3.1 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 2.7 PID_FOXO_PATHWAY FoxO family signaling
0.1 2.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 2.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 2.3 PID_ARF6_PATHWAY Arf6 signaling events
0.1 2.2 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.6 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 1.3 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.2 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.1 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.9 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 0.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.9 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 3.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 2.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 2.4 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.4 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 2.3 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.2 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 2.1 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.1 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 2.0 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.9 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.2 1.7 REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 1.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 1.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.5 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.4 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 1.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.2 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor