Motif ID: Myb
Z-value: 2.051
Transcription factors associated with Myb:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Myb | ENSMUSG00000019982.8 | Myb |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Myb | mm10_v2_chr10_-_21160925_21160984 | 0.76 | 2.6e-04 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 161 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 20.7 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.7 | 12.2 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 1.4 | 8.5 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.6 | 6.9 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.1 | 5.8 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.3 | 5.1 | GO:0030953 | astral microtubule organization(GO:0030953) |
| 0.4 | 4.9 | GO:0098989 | NMDA selective glutamate receptor signaling pathway(GO:0098989) |
| 0.3 | 4.9 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.6 | 4.7 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.4 | 4.4 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.5 | 4.3 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.8 | 4.1 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 0.6 | 4.0 | GO:0000279 | M phase(GO:0000279) |
| 0.1 | 4.0 | GO:0006406 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.6 | 3.8 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 0.1 | 3.7 | GO:0048255 | mRNA stabilization(GO:0048255) |
| 1.2 | 3.6 | GO:0072382 | minus-end-directed vesicle transport along microtubule(GO:0072382) |
| 0.1 | 3.5 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 3.3 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 1.0 | 3.0 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 86 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 21.2 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.3 | 11.0 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 8.3 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.1 | 6.7 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.3 | 6.4 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.2 | 5.9 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 5.1 | GO:0005925 | focal adhesion(GO:0005925) |
| 1.6 | 4.9 | GO:0099573 | glutamatergic postsynaptic density(GO:0099573) |
| 0.1 | 4.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 4.1 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.2 | 4.0 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 4.0 | GO:0000922 | spindle pole(GO:0000922) |
| 0.2 | 3.8 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 3.7 | GO:0005921 | gap junction(GO:0005921) |
| 0.2 | 3.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.8 | 3.0 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 0.0 | 3.0 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 3.0 | GO:0000776 | kinetochore(GO:0000776) |
| 0.4 | 2.9 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.1 | 2.9 | GO:0005882 | intermediate filament(GO:0005882) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 107 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 20.7 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 7.3 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 7.0 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
| 1.6 | 6.5 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.4 | 4.9 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 4.7 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.3 | 4.4 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.1 | 4.4 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.2 | 4.3 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.1 | 4.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.7 | 4.0 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.6 | 3.9 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.9 | 3.8 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.1 | 3.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 3.3 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.1 | 3.1 | GO:0045182 | translation regulator activity(GO:0045182) |
| 0.1 | 3.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.2 | 2.9 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 2.8 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 2.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 29 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 14.4 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.1 | 10.9 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
| 0.1 | 5.3 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
| 0.1 | 5.1 | PID_AURORA_A_PATHWAY | Aurora A signaling |
| 0.2 | 4.9 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.1 | 4.2 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 3.7 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 3.6 | PID_P53_REGULATION_PATHWAY | p53 pathway |
| 0.1 | 3.0 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.2 | 2.8 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 2.5 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.0 | 2.4 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 1.9 | PID_ATM_PATHWAY | ATM pathway |
| 0.1 | 1.8 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 1.8 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.4 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 1.3 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.2 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.0 | 1.2 | NABA_COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 0.9 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 51 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 20.7 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.1 | 10.7 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 6.2 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.2 | 5.9 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.2 | 5.4 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.1 | 5.2 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 4.3 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 4.1 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.1 | 4.1 | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.2 | 4.0 | REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.5 | 3.8 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.1 | 3.8 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 3.6 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.1 | 3.5 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 3.3 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.1 | 2.7 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.0 | 2.7 | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.0 | 2.6 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.2 | 2.4 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 2.0 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
