Motif ID: Myf6

Z-value: 1.520


Transcription factors associated with Myf6:

Gene SymbolEntrez IDGene Name
Myf6 ENSMUSG00000035923.3 Myf6



Activity profile for motif Myf6.

activity profile for motif Myf6


Sorted Z-values histogram for motif Myf6

Sorted Z-values for motif Myf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Myf6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_91269759 8.488 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr3_+_118433797 5.593 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
 Gm26871



predicted gene, 26871



chr9_+_27790947 5.327 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr8_-_9771018 5.212 ENSMUST00000110969.3
 Fam155a
family with sequence similarity 155, member A
chr11_+_50602072 5.099 ENSMUST00000040523.8
 Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr15_-_66812593 4.785 ENSMUST00000100572.3
 Sla
src-like adaptor
chr4_-_64046925 4.763 ENSMUST00000107377.3
 Tnc
tenascin C
chr9_-_112185939 4.593 ENSMUST00000070218.5
 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr3_+_89520152 4.128 ENSMUST00000000811.7
 Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr1_-_3671498 4.097 ENSMUST00000070533.4
 Xkr4
X Kell blood group precursor related family member 4
chr6_-_37299950 3.881 ENSMUST00000101532.3
 Dgki
diacylglycerol kinase, iota
chr11_+_104231573 3.871 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
 Mapt


microtubule-associated protein tau


chr8_+_125995102 3.496 ENSMUST00000046765.8
 Kcnk1
potassium channel, subfamily K, member 1
chr11_+_104231465 3.302 ENSMUST00000145227.1
 Mapt
microtubule-associated protein tau
chr11_+_104231515 3.273 ENSMUST00000106993.3
 Mapt
microtubule-associated protein tau
chr11_-_6065538 3.195 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr16_+_41532999 3.170 ENSMUST00000099761.3
 Lsamp
limbic system-associated membrane protein
chr4_+_119814495 3.097 ENSMUST00000106307.2
 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr9_-_98032983 3.063 ENSMUST00000162295.1
 Clstn2
calsyntenin 2
chr11_+_24076529 3.032 ENSMUST00000148087.1
 Gm12063
predicted gene 12063

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 235 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 17.3 GO:0006813 potassium ion transport(GO:0006813)
1.5 13.4 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 5.8 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.1 5.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.7 5.1 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.5 5.1 GO:0042572 retinol metabolic process(GO:0042572)
0.5 5.0 GO:0046959 habituation(GO:0046959)
1.6 4.9 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.2 4.7 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
1.2 4.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 4.6 GO:0034605 cellular response to heat(GO:0034605)
0.3 4.5 GO:0030574 collagen catabolic process(GO:0030574)
1.1 4.4 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.7 4.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.3 4.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 4.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.2 3.8 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 3.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 3.7 GO:0061029 eyelid development in camera-type eye(GO:0061029)
1.2 3.6 GO:1990034 calcium ion export from cell(GO:1990034)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.3 13.4 GO:0045298 tubulin complex(GO:0045298)
0.1 11.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 9.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 8.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 7.2 GO:0031594 neuromuscular junction(GO:0031594)
0.2 6.0 GO:0030673 axolemma(GO:0030673)
0.0 5.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 4.8 GO:0005614 interstitial matrix(GO:0005614)
1.1 4.4 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.1 4.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.3 GO:0031672 A band(GO:0031672)
0.3 4.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 4.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 3.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 3.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.9 3.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.8 3.3 GO:0044307 dendritic branch(GO:0044307)
0.1 3.3 GO:0051233 spindle midzone(GO:0051233)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 175 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 13.4 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 7.5 GO:0017124 SH3 domain binding(GO:0017124)
0.2 7.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 6.2 GO:0005516 calmodulin binding(GO:0005516)
0.5 6.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
1.7 5.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.7 5.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 5.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.6 4.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 4.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 4.9 GO:0003779 actin binding(GO:0003779)
0.8 4.8 GO:0045545 syndecan binding(GO:0045545)
0.7 4.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.6 4.7 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 4.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
1.5 4.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.6 4.4 GO:0015616 DNA translocase activity(GO:0015616)
1.0 4.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.7 4.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 4.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 12.1 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 7.0 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 6.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 5.9 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.2 4.5 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 4.1 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.0 ST_ADRENERGIC Adrenergic Pathway
0.1 3.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.2 3.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 3.4 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 3.2 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 3.1 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 3.0 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 2.6 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 2.4 PID_EPO_PATHWAY EPO signaling pathway
0.0 2.2 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.0 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 2.0 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 2.0 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 1.7 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 13.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.5 11.3 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 8.8 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.3 6.7 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.9 6.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 5.7 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 4.9 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 4.7 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 4.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 4.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.2 4.2 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 3.7 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 3.0 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 2.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3 2.7 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 2.4 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 2.0 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 2.0 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 2.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases