Motif ID: Myf6

Z-value: 1.520


Transcription factors associated with Myf6:

Gene SymbolEntrez IDGene Name
Myf6 ENSMUSG00000035923.3 Myf6



Activity profile for motif Myf6.

activity profile for motif Myf6


Sorted Z-values histogram for motif Myf6

Sorted Z-values for motif Myf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Myf6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_91269759 8.488 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr3_+_118433797 5.593 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
Gm26871



predicted gene, 26871



chr9_+_27790947 5.327 ENSMUST00000115243.2
Opcml
opioid binding protein/cell adhesion molecule-like
chr8_-_9771018 5.212 ENSMUST00000110969.3
Fam155a
family with sequence similarity 155, member A
chr11_+_50602072 5.099 ENSMUST00000040523.8
Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr15_-_66812593 4.785 ENSMUST00000100572.3
Sla
src-like adaptor
chr4_-_64046925 4.763 ENSMUST00000107377.3
Tnc
tenascin C
chr9_-_112185939 4.593 ENSMUST00000070218.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr3_+_89520152 4.128 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr1_-_3671498 4.097 ENSMUST00000070533.4
Xkr4
X Kell blood group precursor related family member 4
chr6_-_37299950 3.881 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chr11_+_104231573 3.871 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr8_+_125995102 3.496 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr11_+_104231465 3.302 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr11_+_104231515 3.273 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr11_-_6065538 3.195 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr16_+_41532999 3.170 ENSMUST00000099761.3
Lsamp
limbic system-associated membrane protein
chr4_+_119814495 3.097 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr9_-_98032983 3.063 ENSMUST00000162295.1
Clstn2
calsyntenin 2
chr11_+_24076529 3.032 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr2_-_104409992 3.013 ENSMUST00000149466.1
ENSMUST00000139015.1
D430041D05Rik

RIKEN cDNA D430041D05 gene

chr11_+_104231390 2.992 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chrX_+_73503074 2.957 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr13_+_29014399 2.755 ENSMUST00000146336.1
ENSMUST00000130109.1
A330102I10Rik

RIKEN cDNA A330102I10 gene

chr16_-_67620880 2.721 ENSMUST00000114292.1
ENSMUST00000120898.1
Cadm2

cell adhesion molecule 2

chr6_-_126740151 2.650 ENSMUST00000112242.1
Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr16_-_74411292 2.639 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr2_-_104410334 2.448 ENSMUST00000089726.3
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr14_-_102982630 2.389 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr16_+_7069825 2.323 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_-_111259192 2.299 ENSMUST00000169020.1
ENSMUST00000003404.8
Glg1

golgi apparatus protein 1

chr6_-_101377897 2.296 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr1_-_119837338 2.286 ENSMUST00000163435.1
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr2_-_36104060 2.247 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr8_-_11008458 2.244 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr16_-_74411776 2.211 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr2_+_48949495 2.209 ENSMUST00000112745.1
Mbd5
methyl-CpG binding domain protein 5
chr2_-_25319095 2.173 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr5_+_117413977 2.160 ENSMUST00000180430.1
Ksr2
kinase suppressor of ras 2
chr18_+_65873478 2.160 ENSMUST00000025395.8
ENSMUST00000173530.1
Grp

gastrin releasing peptide

chr15_+_81936911 2.146 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr11_-_108343917 2.139 ENSMUST00000059595.4
Prkca
protein kinase C, alpha
chr5_-_25498748 2.130 ENSMUST00000173174.1
Kmt2c
lysine (K)-specific methyltransferase 2C
chr13_-_76385028 2.109 ENSMUST00000099365.1
Gm10760
predicted gene 10760
chr4_+_144892813 2.099 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr2_-_131042682 2.091 ENSMUST00000028787.5
ENSMUST00000110239.1
ENSMUST00000110234.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr19_+_26605106 2.065 ENSMUST00000025862.7
ENSMUST00000176030.1
Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chrX_+_159627534 2.062 ENSMUST00000073094.3
Sh3kbp1
SH3-domain kinase binding protein 1
chr5_-_137600650 2.052 ENSMUST00000111007.1
ENSMUST00000133705.1
Mospd3

motile sperm domain containing 3

chr9_+_45370185 2.031 ENSMUST00000085939.6
Fxyd6
FXYD domain-containing ion transport regulator 6
chr14_+_61138445 2.000 ENSMUST00000089394.3
ENSMUST00000119509.1
Sacs

sacsin

chr5_-_71095765 1.995 ENSMUST00000000572.5
Gabra2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chr16_-_97170707 1.985 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr10_-_127620960 1.949 ENSMUST00000121829.1
Lrp1
low density lipoprotein receptor-related protein 1
chr1_-_134955847 1.940 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr5_-_25498702 1.930 ENSMUST00000173073.1
ENSMUST00000045291.7
Kmt2c

lysine (K)-specific methyltransferase 2C

chr8_+_124793013 1.915 ENSMUST00000167588.1
Trim67
tripartite motif-containing 67
chr9_+_44043384 1.873 ENSMUST00000114840.1
Thy1
thymus cell antigen 1, theta
chr18_+_34247685 1.849 ENSMUST00000066133.6
Apc
adenomatosis polyposis coli
chr11_+_63133068 1.848 ENSMUST00000108700.1
Pmp22
peripheral myelin protein 22
chr8_+_124793061 1.845 ENSMUST00000041106.7
Trim67
tripartite motif-containing 67
chr5_+_105415738 1.836 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr10_-_8518801 1.836 ENSMUST00000061601.7
Ust
uronyl-2-sulfotransferase
chr6_-_121473630 1.833 ENSMUST00000046373.5
Iqsec3
IQ motif and Sec7 domain 3
chr7_-_73740917 1.824 ENSMUST00000169090.1
A830073O21Rik
RIKEN cDNA A830073O21 gene
chr9_-_40531362 1.805 ENSMUST00000119373.1
Gramd1b
GRAM domain containing 1B
chr7_+_73740277 1.792 ENSMUST00000107456.2
Fam174b
family with sequence similarity 174, member B
chr10_-_127620922 1.786 ENSMUST00000118455.1
Lrp1
low density lipoprotein receptor-related protein 1
chr1_-_21961581 1.770 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr13_-_96132568 1.761 ENSMUST00000161263.1
Sv2c
synaptic vesicle glycoprotein 2c
chr10_-_43174521 1.757 ENSMUST00000040275.7
Sobp
sine oculis-binding protein homolog (Drosophila)
chrX_+_159627265 1.750 ENSMUST00000112456.2
Sh3kbp1
SH3-domain kinase binding protein 1
chr2_-_131043088 1.732 ENSMUST00000110240.3
ENSMUST00000066958.4
ENSMUST00000110235.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr5_+_30588078 1.716 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr11_+_121702393 1.716 ENSMUST00000036742.7
Metrnl
meteorin, glial cell differentiation regulator-like
chrX_-_105929206 1.707 ENSMUST00000134381.1
ENSMUST00000154866.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr12_-_70347536 1.704 ENSMUST00000110520.2
ENSMUST00000110522.2
ENSMUST00000167755.1
Trim9


tripartite motif-containing 9


chr17_+_24488773 1.689 ENSMUST00000024958.7
Caskin1
CASK interacting protein 1
chr4_+_130792513 1.680 ENSMUST00000070478.3
Sdc3
syndecan 3
chr18_-_36197343 1.674 ENSMUST00000115713.1
ENSMUST00000115712.1
Nrg2

neuregulin 2

chr11_+_115163333 1.662 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr7_+_122671378 1.661 ENSMUST00000182563.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chrX_-_105929333 1.639 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chr3_-_158562199 1.632 ENSMUST00000106044.1
Lrrc7
leucine rich repeat containing 7
chr4_+_144893077 1.610 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_-_134955908 1.601 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr13_-_97747399 1.597 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_-_22805994 1.595 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr6_-_12749193 1.566 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr1_-_136260873 1.562 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr18_-_38601268 1.562 ENSMUST00000025295.6
Spry4
sprouty homolog 4 (Drosophila)
chr8_-_73353477 1.543 ENSMUST00000119826.1
Large
like-glycosyltransferase
chr13_-_117025505 1.541 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr1_-_119836999 1.522 ENSMUST00000163621.1
ENSMUST00000168303.1
Ptpn4

protein tyrosine phosphatase, non-receptor type 4

chr4_-_88033328 1.517 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr18_-_42899470 1.509 ENSMUST00000120632.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr12_+_105453831 1.502 ENSMUST00000178224.1
D430019H16Rik
RIKEN cDNA D430019H16 gene
chr6_+_125145235 1.485 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr7_+_44590886 1.475 ENSMUST00000107906.3
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr19_-_57197435 1.465 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr10_+_29211637 1.458 ENSMUST00000092627.4
9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr10_-_75560330 1.451 ENSMUST00000051129.9
Fam211b
family with sequence similarity 211, member B
chr4_+_102254993 1.443 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr6_-_53068562 1.443 ENSMUST00000074541.5
Jazf1
JAZF zinc finger 1
chr1_+_181352618 1.440 ENSMUST00000161880.1
ENSMUST00000027795.7
Cnih3

cornichon homolog 3 (Drosophila)

chr16_+_17276337 1.433 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
Tmem191c


transmembrane protein 191C


chr15_+_81936753 1.428 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr1_-_180195981 1.428 ENSMUST00000027766.6
ENSMUST00000161814.1
Adck3

aarF domain containing kinase 3

chr14_+_69029289 1.423 ENSMUST00000014957.8
Stc1
stanniocalcin 1
chr9_-_59036387 1.396 ENSMUST00000068664.5
Neo1
neogenin
chr8_-_17535251 1.391 ENSMUST00000082104.6
Csmd1
CUB and Sushi multiple domains 1
chr19_-_57197377 1.385 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr1_+_57377593 1.370 ENSMUST00000042734.2
1700066M21Rik
RIKEN cDNA 1700066M21 gene
chr2_+_158667119 1.359 ENSMUST00000045503.4
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr4_+_103619580 1.358 ENSMUST00000106827.1
Dab1
disabled 1
chr7_+_57591147 1.356 ENSMUST00000039697.7
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr16_+_93683184 1.352 ENSMUST00000039620.6
Cbr3
carbonyl reductase 3
chr4_+_144893127 1.348 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr14_+_70555900 1.344 ENSMUST00000163060.1
Hr
hairless
chr2_+_118779703 1.331 ENSMUST00000063975.3
ENSMUST00000037547.2
ENSMUST00000110846.1
ENSMUST00000110843.1
Disp2



dispatched homolog 2 (Drosophila)



chr9_+_13621646 1.328 ENSMUST00000034401.8
Maml2
mastermind like 2 (Drosophila)
chr16_-_67620805 1.308 ENSMUST00000120594.1
Cadm2
cell adhesion molecule 2
chr10_+_39732099 1.298 ENSMUST00000019986.6
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr7_+_144284385 1.297 ENSMUST00000097929.2
Shank2
SH3/ankyrin domain gene 2
chr17_-_83631892 1.296 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr2_+_180598219 1.295 ENSMUST00000103059.1
Col9a3
collagen, type IX, alpha 3
chr6_+_21215472 1.284 ENSMUST00000081542.5
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr13_-_51567084 1.283 ENSMUST00000021898.5
Shc3
src homology 2 domain-containing transforming protein C3
chr11_+_120713919 1.275 ENSMUST00000026139.7
ENSMUST00000151852.1
Lrrc45

leucine rich repeat containing 45

chr9_-_54501496 1.249 ENSMUST00000118600.1
ENSMUST00000118163.1
Dmxl2

Dmx-like 2

chr2_+_158666690 1.245 ENSMUST00000103116.3
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr12_+_71015966 1.244 ENSMUST00000046305.5
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr2_-_148732457 1.238 ENSMUST00000028926.6
Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr10_+_111164794 1.234 ENSMUST00000105275.1
ENSMUST00000095310.1
Osbpl8

oxysterol binding protein-like 8

chr4_-_47057296 1.226 ENSMUST00000107747.1
ENSMUST00000084616.2
Anks6

ankyrin repeat and sterile alpha motif domain containing 6

chr10_+_7589788 1.214 ENSMUST00000134346.1
ENSMUST00000019931.5
Lrp11

low density lipoprotein receptor-related protein 11

chr6_+_6863769 1.214 ENSMUST00000031768.6
Dlx6
distal-less homeobox 6
chr1_+_135584773 1.210 ENSMUST00000067468.4
Gm4793
predicted gene 4793
chr6_-_77979515 1.207 ENSMUST00000159626.1
ENSMUST00000075340.5
ENSMUST00000162273.1
Ctnna2


catenin (cadherin associated protein), alpha 2


chr19_-_57197496 1.199 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr10_-_42276688 1.187 ENSMUST00000175881.1
ENSMUST00000056974.3
Foxo3

forkhead box O3

chr8_-_69791170 1.173 ENSMUST00000131784.1
Zfp866
zinc finger protein 866
chr7_+_46396439 1.165 ENSMUST00000025202.6
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr19_-_57197556 1.162 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr2_-_130906338 1.154 ENSMUST00000146975.1
4930402H24Rik
RIKEN cDNA 4930402H24 gene
chr7_+_3303503 1.147 ENSMUST00000100301.4
Prkcg
protein kinase C, gamma
chr15_-_78120011 1.146 ENSMUST00000019290.2
Cacng2
calcium channel, voltage-dependent, gamma subunit 2
chr3_+_68494208 1.143 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr1_+_81077274 1.139 ENSMUST00000068275.5
ENSMUST00000113494.2
Nyap2

neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2

chr2_-_181135103 1.136 ENSMUST00000149964.2
ENSMUST00000103050.3
ENSMUST00000081528.6
ENSMUST00000049792.8
ENSMUST00000103048.3
ENSMUST00000103047.3
ENSMUST00000129073.1
ENSMUST00000144592.1
ENSMUST00000139458.1
ENSMUST00000154164.1
ENSMUST00000123336.1
ENSMUST00000129361.1
ENSMUST00000103051.2
Kcnq2












potassium voltage-gated channel, subfamily Q, member 2












chr2_+_82053222 1.134 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr16_-_17576631 1.133 ENSMUST00000164545.1
ENSMUST00000164490.1
ENSMUST00000172164.1
Slc7a4


solute carrier family 7 (cationic amino acid transporter, y+ system), member 4


chr9_+_40269430 1.128 ENSMUST00000171835.2
Scn3b
sodium channel, voltage-gated, type III, beta
chr6_-_38254009 1.125 ENSMUST00000169256.1
D630045J12Rik
RIKEN cDNA D630045J12 gene
chr6_-_77979652 1.124 ENSMUST00000161846.1
ENSMUST00000160894.1
Ctnna2

catenin (cadherin associated protein), alpha 2

chr2_-_25319187 1.108 ENSMUST00000114312.1
Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr11_-_106487833 1.107 ENSMUST00000106801.1
Ern1
endoplasmic reticulum (ER) to nucleus signalling 1
chr14_+_65968483 1.096 ENSMUST00000022616.6
Clu
clusterin
chr7_+_3303643 1.092 ENSMUST00000172109.1
Prkcg
protein kinase C, gamma
chr5_-_103211251 1.080 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr13_+_81711407 1.077 ENSMUST00000057598.5
Mblac2
metallo-beta-lactamase domain containing 2
chr5_+_123142187 1.077 ENSMUST00000174836.1
ENSMUST00000163030.2
Setd1b

SET domain containing 1B

chr11_+_29373618 1.068 ENSMUST00000040182.6
ENSMUST00000109477.1
Ccdc88a

coiled coil domain containing 88A

chr10_+_7589885 1.062 ENSMUST00000130590.1
ENSMUST00000135907.1
Lrp11

low density lipoprotein receptor-related protein 11

chr15_+_81811414 1.057 ENSMUST00000023024.7
Tef
thyrotroph embryonic factor
chr10_-_116473418 1.046 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chrX_-_105929397 1.044 ENSMUST00000113573.1
ENSMUST00000130980.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr19_+_4855129 1.042 ENSMUST00000119694.1
Ctsf
cathepsin F
chr9_-_39604124 1.038 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chr3_-_89773221 1.036 ENSMUST00000038450.1
4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr6_-_82939676 1.034 ENSMUST00000000641.9
ENSMUST00000113982.1
Sema4f

sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain

chr16_-_22657165 1.013 ENSMUST00000089925.3
Dgkg
diacylglycerol kinase, gamma
chr6_-_119848093 1.012 ENSMUST00000079582.4
Erc1
ELKS/RAB6-interacting/CAST family member 1
chr5_+_3343893 1.011 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr4_+_102254739 1.009 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr9_+_40269273 0.999 ENSMUST00000176185.1
Scn3b
sodium channel, voltage-gated, type III, beta
chr10_-_127621107 0.998 ENSMUST00000049149.8
Lrp1
low density lipoprotein receptor-related protein 1
chr2_+_55437100 0.993 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr19_-_45816007 0.992 ENSMUST00000079431.3
ENSMUST00000026247.6
ENSMUST00000162528.2
Kcnip2


Kv channel-interacting protein 2


chrX_+_134404780 0.990 ENSMUST00000113224.2
ENSMUST00000113226.1
Drp2

dystrophin related protein 2

chr10_+_90576872 0.984 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr9_+_40269202 0.983 ENSMUST00000114956.3
ENSMUST00000049941.5
Scn3b

sodium channel, voltage-gated, type III, beta

chr6_+_6863269 0.982 ENSMUST00000160937.2
ENSMUST00000171311.1
Dlx6

distal-less homeobox 6

chr7_+_130936172 0.972 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr2_+_83812567 0.964 ENSMUST00000051454.3
Fam171b
family with sequence similarity 171, member B
chr15_+_89532816 0.964 ENSMUST00000167173.1
Shank3
SH3/ankyrin domain gene 3
chr1_-_119837613 0.961 ENSMUST00000064091.5
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr4_+_155694311 0.954 ENSMUST00000099265.2
B930041F14Rik
RIKEN cDNA B930041F14 gene
chr2_+_107290590 0.950 ENSMUST00000037012.2
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr8_-_84773381 0.932 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr16_-_34095983 0.930 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr5_+_107497762 0.928 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr7_-_74013676 0.928 ENSMUST00000026896.4
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chrX_-_73880831 0.928 ENSMUST00000102871.3
L1cam
L1 cell adhesion molecule
chr15_-_98567630 0.924 ENSMUST00000012104.6
Ccnt1
cyclin T1
chr10_+_90576708 0.917 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
Anks1b



ankyrin repeat and sterile alpha motif domain containing 1B



chr1_+_167598450 0.916 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr5_+_19227046 0.916 ENSMUST00000088516.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_-_20291728 0.902 ENSMUST00000115393.2
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chrX_-_20291776 0.902 ENSMUST00000072451.4
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.5 13.4 GO:1900034 regulation of cellular response to heat(GO:1900034)
1.2 3.6 GO:1990034 calcium ion export from cell(GO:1990034)
1.2 4.7 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
1.2 4.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.1 4.4 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
1.1 3.3 GO:1900673 olefin metabolic process(GO:1900673)
1.1 3.2 GO:0032430 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.7 5.1 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.7 2.2 GO:0061744 motor behavior(GO:0061744) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.7 2.1 GO:2000705 negative regulation of anion channel activity(GO:0010360) regulation of dense core granule biogenesis(GO:2000705)
0.7 4.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.7 2.0 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.6 2.3 GO:0009414 response to water deprivation(GO:0009414)
0.6 1.7 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.5 2.6 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.5 5.0 GO:0046959 habituation(GO:0046959)
0.5 1.8 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.5 1.4 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.5 5.1 GO:0042572 retinol metabolic process(GO:0042572)
0.4 2.2 GO:0032423 regulation of mismatch repair(GO:0032423)
0.4 1.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.4 1.6 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.4 1.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.4 2.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 3.1 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.3 1.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) lateral motor column neuron migration(GO:0097477)
0.3 4.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.3 2.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.3 0.9 GO:0072720 response to dithiothreitol(GO:0072720)
0.3 2.1 GO:1902988 neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.3 0.9 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.3 0.9 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.3 1.1 GO:0015871 choline transport(GO:0015871)
0.3 4.5 GO:0030574 collagen catabolic process(GO:0030574)
0.3 0.8 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.3 1.7 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.3 2.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 0.8 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.3 2.5 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 0.5 GO:1901800 positive regulation of proteasomal protein catabolic process(GO:1901800)
0.2 1.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 0.7 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 3.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.2 2.1 GO:0071420 cellular response to histamine(GO:0071420)
0.2 0.7 GO:1900365 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365)
0.2 2.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 0.9 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 1.8 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.9 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.2 1.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 1.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 1.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.6 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 1.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.2 1.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.6 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.2 0.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.2 1.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.2 0.6 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 2.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2 1.8 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 3.8 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.2 1.4 GO:0015879 carnitine transport(GO:0015879)
0.2 1.0 GO:1904717 positive regulation of synapse structural plasticity(GO:0051835) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2 1.3 GO:0030969 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.2 0.8 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 2.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 0.6 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 2.2 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.2 1.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 0.5 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.2 1.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.2 3.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 0.5 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.2 0.5 GO:0031133 regulation of axon diameter(GO:0031133)
0.2 0.8 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.2 0.7 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 3.7 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.2 1.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.2 0.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 3.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 1.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 2.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.9 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 1.0 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.1 1.0 GO:0044838 cell quiescence(GO:0044838)
0.1 1.4 GO:0060536 cartilage morphogenesis(GO:0060536)
0.1 0.6 GO:0061428 embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 1.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 2.3 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 1.8 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.4 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.4 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
0.1 3.0 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.9 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 1.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.1 1.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.6 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.1 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 4.6 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.0 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.1 0.5 GO:0072014 proximal tubule development(GO:0072014)
0.1 0.9 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 1.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.3 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.1 0.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739) amylase secretion(GO:0036394)
0.1 0.6 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.7 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 1.4 GO:0042182 ketone catabolic process(GO:0042182)
0.1 0.4 GO:0070829 heterochromatin maintenance(GO:0070829)
0.1 17.3 GO:0006813 potassium ion transport(GO:0006813)
0.1 0.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.4 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.1 1.8 GO:0032060 bleb assembly(GO:0032060)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.7 GO:0051004 plasma membrane to endosome transport(GO:0048227) regulation of lipoprotein lipase activity(GO:0051004)
0.1 0.7 GO:0030242 pexophagy(GO:0030242)
0.1 0.3 GO:0006971 hypotonic response(GO:0006971)
0.1 0.9 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.3 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.5 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 2.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 0.3 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1 0.2 GO:0070571 negative regulation of neuron projection regeneration(GO:0070571)
0.1 0.7 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.1 0.5 GO:0003096 renal sodium ion transport(GO:0003096)
0.1 1.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.5 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0032055 negative regulation of translation in response to stress(GO:0032055) cellular response to cold(GO:0070417)
0.1 1.0 GO:0007413 axonal fasciculation(GO:0007413)
0.1 5.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.3 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.3 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 2.4 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.1 0.1 GO:1905203 regulation of connective tissue replacement(GO:1905203)
0.1 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.1 GO:0030578 PML body organization(GO:0030578)
0.1 0.4 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.1 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.6 GO:0006691 leukotriene metabolic process(GO:0006691)
0.1 5.8 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.1 0.7 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.7 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.1 0.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.2 GO:1901678 iron coordination entity transport(GO:1901678)
0.1 0.9 GO:0001553 luteinization(GO:0001553)
0.1 0.2 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 1.0 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.1 0.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.8 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 3.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 1.0 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.0 4.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.6 GO:0033572 transferrin transport(GO:0033572)
0.0 1.7 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 1.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0003357 pancreatic A cell differentiation(GO:0003310) noradrenergic neuron differentiation(GO:0003357)
0.0 0.0 GO:0097212 lysosomal membrane organization(GO:0097212)
0.0 2.6 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 1.3 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 1.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.6 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.5 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 1.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.4 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 1.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.0 0.3 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.6 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.5 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.3 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.1 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 0.3 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.9 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.7 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.4 GO:0009268 response to pH(GO:0009268)
0.0 1.0 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.7 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 1.1 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 13.4 GO:0045298 tubulin complex(GO:0045298)
1.1 4.4 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.9 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.9 3.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.8 3.3 GO:0044307 dendritic branch(GO:0044307)
0.3 4.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 1.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.3 2.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 1.6 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.3 4.8 GO:0005614 interstitial matrix(GO:0005614)
0.3 0.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 3.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 1.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 1.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 1.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 1.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 3.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 6.0 GO:0030673 axolemma(GO:0030673)
0.2 9.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 1.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 3.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.8 GO:0005883 neurofilament(GO:0005883)
0.2 2.1 GO:0032426 stereocilium tip(GO:0032426)
0.2 2.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 0.6 GO:0019034 viral replication complex(GO:0019034)
0.1 0.7 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 11.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.9 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.4 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.6 GO:0043194 axon initial segment(GO:0043194)
0.1 4.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 2.2 GO:0010369 chromocenter(GO:0010369)
0.1 2.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 4.3 GO:0031672 A band(GO:0031672)
0.1 3.3 GO:0051233 spindle midzone(GO:0051233)
0.1 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.8 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 2.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.4 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 7.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 1.8 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.4 GO:0070820 tertiary granule(GO:0070820)
0.1 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731) platelet dense tubular network membrane(GO:0031095)
0.1 1.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.3 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 1.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.5 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 16.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 5.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.8 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 8.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 1.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 5.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.1 GO:0030424 axon(GO:0030424)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 4.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 2.9 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.8 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.5 GO:0001726 ruffle(GO:0001726)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 13.4 GO:0099609 microtubule lateral binding(GO:0099609)
1.7 5.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.6 4.7 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
1.5 4.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
1.3 3.8 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.0 4.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.8 3.3 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.8 4.8 GO:0045545 syndecan binding(GO:0045545)
0.7 5.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.7 4.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.7 4.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.6 4.4 GO:0015616 DNA translocase activity(GO:0015616)
0.6 4.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 1.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.5 6.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.5 2.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.5 1.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 4.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 3.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.4 1.9 GO:0034235 GPI anchor binding(GO:0034235)
0.3 1.4 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.3 1.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 1.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 0.9 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.3 5.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 1.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 0.8 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.3 1.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 1.8 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 3.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 1.2 GO:0097643 amylin receptor activity(GO:0097643)
0.2 1.0 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.2 1.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 1.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 4.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 1.1 GO:0004359 glutaminase activity(GO:0004359)
0.2 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.7 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.5 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.2 0.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.9 GO:0033691 sialic acid binding(GO:0033691)
0.2 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 7.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 3.2 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 0.4 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 2.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.7 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 2.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.2 GO:2001070 starch binding(GO:2001070)
0.1 1.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.8 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.6 GO:0009374 biotin binding(GO:0009374)
0.1 0.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.8 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 0.3 GO:0004528 phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529)
0.1 3.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.2 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 2.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 2.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.4 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 2.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 0.6 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 1.1 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.5 GO:0015250 water channel activity(GO:0015250)
0.1 1.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 4.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 7.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 2.8 GO:0005179 hormone activity(GO:0005179)
0.0 2.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 2.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0070492 galactose binding(GO:0005534) oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 6.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0005267 potassium channel activity(GO:0005267)
0.0 0.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 1.1 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 1.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 4.9 GO:0003779 actin binding(GO:0003779)
0.0 1.0 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)
0.0 1.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.1 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 5.9 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.2 4.5 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.2 3.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.0 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 2.0 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 4.0 ST_ADRENERGIC Adrenergic Pathway
0.1 0.5 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 3.2 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 3.1 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.8 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.1 3.4 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 2.4 PID_EPO_PATHWAY EPO signaling pathway
0.1 0.5 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 3.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 4.1 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.7 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 7.0 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 0.7 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.6 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.4 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 1.0 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 2.6 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 6.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 3.0 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 2.2 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 2.0 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.0 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.3 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.3 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.5 11.3 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 2.7 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 13.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.3 6.7 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 1.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 3.7 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 3.0 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 2.0 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.2 0.5 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 4.7 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.2 4.9 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 1.6 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 5.7 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 4.2 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 8.8 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 4.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.0 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 4.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.4 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.8 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.9 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.8 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.1 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.1 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.9 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 0.8 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.5 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.1 0.5 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 0.8 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.7 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.0 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 2.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.4 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 0.5 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.9 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.0 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.4 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.4 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.9 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.1 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.3 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.0 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.6 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 0.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis