Motif ID: Myod1

Z-value: 0.454


Transcription factors associated with Myod1:

Gene SymbolEntrez IDGene Name
Myod1 ENSMUSG00000009471.3 Myod1



Activity profile for motif Myod1.

activity profile for motif Myod1


Sorted Z-values histogram for motif Myod1

Sorted Z-values for motif Myod1



Network of associatons between targets according to the STRING database.



First level regulatory network of Myod1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_78773452 0.442 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr7_-_30973464 0.427 ENSMUST00000001279.8
Lsr
lipolysis stimulated lipoprotein receptor
chr9_+_30942541 0.403 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr17_-_35703971 0.393 ENSMUST00000148065.1
Ddr1
discoidin domain receptor family, member 1
chr4_+_42240639 0.388 ENSMUST00000117202.2
Gm10600
predicted gene 10600
chr17_-_23684019 0.387 ENSMUST00000085989.5
Cldn9
claudin 9
chr1_-_118982551 0.380 ENSMUST00000159678.1
Gli2
GLI-Kruppel family member GLI2
chr13_-_60177357 0.377 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr1_-_119053339 0.370 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr4_+_45184815 0.370 ENSMUST00000134280.1
ENSMUST00000044773.5
Frmpd1

FERM and PDZ domain containing 1

chrX_-_52613913 0.361 ENSMUST00000069360.7
Gpc3
glypican 3
chr7_+_96210107 0.357 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr2_-_170406501 0.354 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr10_-_8518801 0.337 ENSMUST00000061601.7
Ust
uronyl-2-sulfotransferase
chr5_-_98566762 0.327 ENSMUST00000086912.4
1700010H22Rik
RIKEN cDNA 1700010H22 gene
chr5_+_115011111 0.320 ENSMUST00000031530.5
Sppl3
signal peptide peptidase 3
chr2_-_84775388 0.312 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr15_+_25622525 0.308 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr2_-_84775420 0.307 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr8_-_61902669 0.301 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 0.8 GO:0060032 notochord regression(GO:0060032)
0.2 0.6 GO:0072180 mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.2 0.6 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.4 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 0.4 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.4 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.8 GO:0097542 ciliary tip(GO:0097542)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.3 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.3 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.1 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.8 GO:0001848 complement binding(GO:0001848)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)

Gene overrepresentation in C2:CP category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.6 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.3 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 0.6 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine