Motif ID: Neurod2_Bhlha15_Bhlhe22_Olig1

Z-value: 0.724

Transcription factors associated with Neurod2_Bhlha15_Bhlhe22_Olig1:

Gene SymbolEntrez IDGene Name
Bhlha15 ENSMUSG00000052271.7 Bhlha15
Bhlhe22 ENSMUSG00000025128.6 Bhlhe22
Neurod2 ENSMUSG00000038255.6 Neurod2
Olig1 ENSMUSG00000046160.5 Olig1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe22mm10_v2_chr3_+_18054258_180543250.662.8e-03Click!
Neurod2mm10_v2_chr11_-_98329641_983296540.653.3e-03Click!
Olig1mm10_v2_chr16_+_91269759_912697780.616.7e-03Click!


Activity profile for motif Neurod2_Bhlha15_Bhlhe22_Olig1.

activity profile for motif Neurod2_Bhlha15_Bhlhe22_Olig1


Sorted Z-values histogram for motif Neurod2_Bhlha15_Bhlhe22_Olig1

Sorted Z-values for motif Neurod2_Bhlha15_Bhlhe22_Olig1



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurod2_Bhlha15_Bhlhe22_Olig1

PNG image of the network

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Top targets:


Showing 1 to 20 of 145 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_36989504 3.066 ENSMUST00000169189.1
 H2-M5
histocompatibility 2, M region locus 5
chr16_+_43235856 2.981 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20
chr10_-_25200110 2.916 ENSMUST00000100012.2
 Akap7
A kinase (PRKA) anchor protein 7
chr1_-_44218952 2.607 ENSMUST00000054801.3
 Mettl21e
methyltransferase like 21E
chr1_-_111864869 2.466 ENSMUST00000035462.5
 Dsel
dermatan sulfate epimerase-like
chr5_+_124194894 2.309 ENSMUST00000159053.1
ENSMUST00000162577.1
 Gm16338

predicted gene 16338

chr1_-_150392719 2.186 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
 BC003331


cDNA sequence BC003331


chr1_+_177444653 2.179 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr3_-_120886691 2.054 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
 6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr1_+_150392794 1.986 ENSMUST00000124973.2
 Tpr
translocated promoter region
chr2_+_69670100 1.739 ENSMUST00000100050.3
 Klhl41
kelch-like 41
chr3_+_138065052 1.644 ENSMUST00000163080.2
 1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr4_-_141598206 1.540 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
 Fblim1


filamin binding LIM protein 1


chr9_+_72985568 1.439 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
 Ccpg1


cell cycle progression 1


chr13_-_62607499 1.423 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr9_+_72985504 1.347 ENSMUST00000156879.1
 Ccpg1
cell cycle progression 1
chr2_+_65930117 1.340 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr5_+_75152274 1.235 ENSMUST00000000476.8
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr5_-_103977360 1.134 ENSMUST00000048118.8
 Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
chr1_+_177445660 1.128 ENSMUST00000077225.6
 Zbtb18
zinc finger and BTB domain containing 18

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 3.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 3.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 3.0 GO:0021766 hippocampus development(GO:0021766)
0.5 2.9 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 2.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.5 2.5 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.7 2.0 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 1.7 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.1 1.7 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 1.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 1.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.4 1.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.1 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 1.1 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.2 1.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 1.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 0.9 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.8 GO:0001523 retinoid metabolic process(GO:0001523)
0.1 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.0 GO:0030315 T-tubule(GO:0030315)
0.1 3.3 GO:0045171 intercellular bridge(GO:0045171)
0.3 2.0 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 1.7 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.7 GO:0031143 pseudopodium(GO:0031143)
0.1 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.0 1.2 GO:0005902 microvillus(GO:0005902)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 1.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.0 GO:0042588 zymogen granule(GO:0042588)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.1 0.5 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.1 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.1 GO:0042605 peptide antigen binding(GO:0042605)
0.1 2.9 GO:0016208 AMP binding(GO:0016208)
0.0 2.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.6 GO:0008168 methyltransferase activity(GO:0008168)
0.1 2.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 2.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 1.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 1.5 GO:0031005 filamin binding(GO:0031005)
0.2 1.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 1.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 0.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin binding(GO:0030332)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 1.4 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.2 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 1.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions