---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_-_118052235	3.112	ENSMUST00000022725.2	Dct	dopachrome tautomerase
chr6_+_17306335	2.993	ENSMUST00000007799.6 ENSMUST00000115456.1 ENSMUST00000115455.2 ENSMUST00000130505.1	Cav1	caveolin 1, caveolae protein
chr11_+_78324200	2.962	ENSMUST00000102478.3	Aldoc	aldolase C, fructose-bisphosphate
chr3_-_8667033	2.356	ENSMUST00000042412.3	Hey1	hairy/enhancer-of-split related with YRPW motif 1
chr5_-_53707532	2.234	ENSMUST00000031093.3	Cckar	cholecystokinin A receptor
chr6_+_135362931	2.068	ENSMUST00000032330.9	Emp1	epithelial membrane protein 1
chr10_+_86302854	1.938	ENSMUST00000132307.1	Timp3	tissue inhibitor of metalloproteinase 3
chr2_+_13573927	1.819	ENSMUST00000141365.1 ENSMUST00000028062.2	Vim	vimentin
chr6_+_17306415	1.800	ENSMUST00000150901.1	Cav1	caveolin 1, caveolae protein
chr14_+_31134853	1.793	ENSMUST00000090212.4	Nt5dc2	5'-nucleotidase domain containing 2
chr9_+_44134562	1.692	ENSMUST00000034650.8 ENSMUST00000098852.2	Mcam	melanoma cell adhesion molecule
chr10_+_57784859	1.672	ENSMUST00000020024.5	Fabp7	fatty acid binding protein 7, brain
chr7_+_45017953	1.655	ENSMUST00000044111.7	Rras	Harvey rat sarcoma oncogene, subgroup R
chr7_-_116237767	1.636	ENSMUST00000182834.1	Plekha7	pleckstrin homology domain containing, family A member 7
chr16_+_90831113	1.624	ENSMUST00000037539.7 ENSMUST00000099543.3	Eva1c	eva-1 homolog C (C. elegans)
chr11_+_61485431	1.607	ENSMUST00000064783.3 ENSMUST00000040522.6	Mfap4	microfibrillar-associated protein 4
chr6_+_29433248	1.466	ENSMUST00000101617.2 ENSMUST00000065090.5	Flnc	filamin C, gamma
chr4_-_93335510	1.465	ENSMUST00000066774.4	Tusc1	tumor suppressor candidate 1
chr14_+_59625281	1.393	ENSMUST00000053949.5	Shisa2	shisa homolog 2 (Xenopus laevis)
chr1_+_185454803	1.375	ENSMUST00000061093.6	Slc30a10	solute carrier family 30, member 10
chr2_+_27079371	1.360	ENSMUST00000091233.6	Adamtsl2	ADAMTS-like 2
chr19_-_42752710	1.293	ENSMUST00000076505.3	Pyroxd2	pyridine nucleotide-disulphide oxidoreductase domain 2
chr11_+_78322965	1.204	ENSMUST00000017534.8	Aldoc	aldolase C, fructose-bisphosphate
chr3_-_131272077	1.196	ENSMUST00000029610.8	Hadh	hydroxyacyl-Coenzyme A dehydrogenase
chr5_+_52582320	1.187	ENSMUST00000177881.1	Gm5866	predicted gene 5866
chr6_+_29433131	1.180	ENSMUST00000090474.4	Flnc	filamin C, gamma
chr11_-_94601862	1.172	ENSMUST00000103164.3	Acsf2	acyl-CoA synthetase family member 2
chr7_+_130936172	1.072	ENSMUST00000006367.7	Htra1	HtrA serine peptidase 1
chr1_-_191183244	1.037	ENSMUST00000027941.8	Atf3	activating transcription factor 3
chr10_-_77113676	0.995	ENSMUST00000072755.4 ENSMUST00000105409.1	Col18a1	collagen, type XVIII, alpha 1
chr5_-_98566762	0.969	ENSMUST00000086912.4	1700010H22Rik	RIKEN cDNA 1700010H22 gene
chr10_+_57784914	0.962	ENSMUST00000165013.1	Fabp7	fatty acid binding protein 7, brain
chr12_+_110279228	0.935	ENSMUST00000097228.4	Dio3	deiodinase, iodothyronine type III
chr18_-_78123324	0.929	ENSMUST00000160292.1 ENSMUST00000091813.5	Slc14a1	solute carrier family 14 (urea transporter), member 1
chrX_-_48034842	0.909	ENSMUST00000039026.7	Apln	apelin
chr1_+_43730593	0.896	ENSMUST00000027217.8	1500015O10Rik	RIKEN cDNA 1500015O10 gene
chr3_+_94933041	0.881	ENSMUST00000090839.5	Selenbp1	selenium binding protein 1
chrX_-_52613913	0.877	ENSMUST00000069360.7	Gpc3	glypican 3
chr13_-_97747373	0.866	ENSMUST00000123535.1	5330416C01Rik	RIKEN cDNA 5330416C01 gene
chr12_-_91746020	0.864	ENSMUST00000166967.1	Ston2	stonin 2
chr6_-_116673790	0.859	ENSMUST00000035842.4	Rassf4	Ras association (RalGDS/AF-6) domain family member 4
chr9_+_104566677	0.853	ENSMUST00000157006.1	Cpne4	copine IV
chr4_+_41762309	0.852	ENSMUST00000108042.2	Il11ra1	interleukin 11 receptor, alpha chain 1
chr4_-_155019399	0.801	ENSMUST00000126098.1 ENSMUST00000176194.1	Plch2	phospholipase C, eta 2
chr9_-_100506844	0.781	ENSMUST00000112874.3	Nck1	non-catalytic region of tyrosine kinase adaptor protein 1
chr17_+_32621319	0.778	ENSMUST00000077639.5	Gm9705	predicted gene 9705
chr7_-_17056669	0.775	ENSMUST00000037762.4	Hif3a	hypoxia inducible factor 3, alpha subunit
chrX_-_52613936	0.739	ENSMUST00000114857.1	Gpc3	glypican 3
chr5_+_137745967	0.734	ENSMUST00000100539.3	Tsc22d4	TSC22 domain family, member 4
chr5_+_137745730	0.727	ENSMUST00000100540.3	Tsc22d4	TSC22 domain family, member 4
chr5_+_137758133	0.720	ENSMUST00000141733.1 ENSMUST00000110985.1	Tsc22d4	TSC22 domain family, member 4
chr9_-_106199253	0.709	ENSMUST00000140761.1	Ppm1m	protein phosphatase 1M
chr3_-_90243073	0.704	ENSMUST00000107369.1	Creb3l4	cAMP responsive element binding protein 3-like 4
chr5_-_134747241	0.692	ENSMUST00000015138.9	Eln	elastin
chr7_+_62476306	0.689	ENSMUST00000097132.3	Atp5l-ps1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g, pseudogene 1
chr11_-_110095937	0.686	ENSMUST00000106664.3 ENSMUST00000046223.7 ENSMUST00000106662.1	Abca8a	ATP-binding cassette, sub-family A (ABC1), member 8a
chr4_-_129227883	0.686	ENSMUST00000106051.1	C77080	expressed sequence C77080
chr7_+_100494044	0.681	ENSMUST00000153287.1	Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)
chr12_+_3891728	0.679	ENSMUST00000172689.1 ENSMUST00000111186.1	Dnmt3a	DNA methyltransferase 3A
chr3_-_116129615	0.673	ENSMUST00000029574.8	Vcam1	vascular cell adhesion molecule 1
chr4_+_137468767	0.666	ENSMUST00000030547.8 ENSMUST00000171332.1	Hspg2	perlecan (heparan sulfate proteoglycan 2)
chr14_-_122451109	0.665	ENSMUST00000081580.2	Gm5089	predicted gene 5089
chr9_-_21798502	0.664	ENSMUST00000034717.5	Kank2	KN motif and ankyrin repeat domains 2
chr11_+_94629741	0.662	ENSMUST00000021239.6	Lrrc59	leucine rich repeat containing 59
chr5_-_77115145	0.656	ENSMUST00000081964.5	Hopx	HOP homeobox
chr4_+_130047840	0.645	ENSMUST00000044565.8 ENSMUST00000132251.1	Col16a1	collagen, type XVI, alpha 1
chr7_+_100493795	0.639	ENSMUST00000129324.1	Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)
chr2_+_152754156	0.628	ENSMUST00000010020.5	Cox4i2	cytochrome c oxidase subunit IV isoform 2
chr7_-_97417730	0.625	ENSMUST00000043077.7	Thrsp	thyroid hormone responsive
chr14_+_31217850	0.624	ENSMUST00000090180.2	Sema3g	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr8_+_94977101	0.623	ENSMUST00000179619.1	Gpr56	G protein-coupled receptor 56
chr5_+_30013141	0.617	ENSMUST00000026845.7	Il6	interleukin 6
chr2_+_119167758	0.615	ENSMUST00000057454.3	Gchfr	GTP cyclohydrolase I feedback regulator
chr2_+_129592818	0.613	ENSMUST00000153491.1 ENSMUST00000161620.1 ENSMUST00000179001.1	Sirpa	signal-regulatory protein alpha
chr7_+_27447978	0.594	ENSMUST00000037399.9 ENSMUST00000108358.1	Blvrb	biliverdin reductase B (flavin reductase (NADPH))
chr4_-_123750236	0.592	ENSMUST00000102636.3	Akirin1	akirin 1
chr2_+_76650264	0.570	ENSMUST00000099986.2	Dfnb59	deafness, autosomal recessive 59 (human)
chr2_-_105399286	0.565	ENSMUST00000006128.6	Rcn1	reticulocalbin 1
chr1_-_72874877	0.561	ENSMUST00000027377.8	Igfbp5	insulin-like growth factor binding protein 5
chr18_-_78206408	0.557	ENSMUST00000163367.1	Slc14a2	solute carrier family 14 (urea transporter), member 2
chr5_-_24581879	0.550	ENSMUST00000088299.4	Gm10221	predicted gene 10221
chr1_-_120120138	0.547	ENSMUST00000112648.1 ENSMUST00000128408.1	Dbi	diazepam binding inhibitor
chr15_-_103366763	0.546	ENSMUST00000023128.6	Itga5	integrin alpha 5 (fibronectin receptor alpha)
chr7_+_27607997	0.545	ENSMUST00000142365.1	Akt2	thymoma viral proto-oncogene 2
chr4_+_133584419	0.543	ENSMUST00000105899.1	Gpn2	GPN-loop GTPase 2
chr2_+_164832862	0.542	ENSMUST00000103093.3 ENSMUST00000017904.2	Ctsa	cathepsin A
chr2_+_164832881	0.529	ENSMUST00000103092.1 ENSMUST00000151493.1 ENSMUST00000127650.1	Ctsa	cathepsin A
chr3_+_95228952	0.529	ENSMUST00000107201.2	Cdc42se1	CDC42 small effector 1
chr3_+_94342092	0.524	ENSMUST00000029794.5	Them5	thioesterase superfamily member 5
chr1_+_172341197	0.523	ENSMUST00000056136.3	Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10
chr5_-_5514730	0.512	ENSMUST00000115445.1 ENSMUST00000179804.1 ENSMUST00000125110.1 ENSMUST00000115446.1	Cldn12	claudin 12
chr14_+_62332068	0.510	ENSMUST00000022499.6	Rnaseh2b	ribonuclease H2, subunit B
chr2_+_30078584	0.505	ENSMUST00000045246.7	Pkn3	protein kinase N3
chr7_-_105482197	0.499	ENSMUST00000047040.2	Prkcdbp	protein kinase C, delta binding protein
chr19_+_6084983	0.497	ENSMUST00000025704.2	Cdca5	cell division cycle associated 5
chr13_+_74639866	0.496	ENSMUST00000169114.1	Erap1	endoplasmic reticulum aminopeptidase 1
chr7_+_30553263	0.488	ENSMUST00000044048.7	Hspb6	heat shock protein, alpha-crystallin-related, B6
chr4_+_100776664	0.488	ENSMUST00000030257.8 ENSMUST00000097955.2	Cachd1	cache domain containing 1
chr5_-_5514873	0.485	ENSMUST00000060947.7	Cldn12	claudin 12
chr5_+_135725713	0.478	ENSMUST00000127096.1	Por	P450 (cytochrome) oxidoreductase
chr6_+_138141569	0.470	ENSMUST00000118091.1	Mgst1	microsomal glutathione S-transferase 1
chr2_-_25469742	0.469	ENSMUST00000114259.2 ENSMUST00000015234.6	Ptgds	prostaglandin D2 synthase (brain)
chr8_-_94876269	0.468	ENSMUST00000046461.7	Dok4	docking protein 4
chr7_-_80403315	0.463	ENSMUST00000147150.1	Furin	furin (paired basic amino acid cleaving enzyme)
chr7_+_27607748	0.461	ENSMUST00000136962.1	Akt2	thymoma viral proto-oncogene 2
chr8_-_67818218	0.458	ENSMUST00000059374.4	Psd3	pleckstrin and Sec7 domain containing 3
chr4_-_63403330	0.456	ENSMUST00000035724.4	Akna	AT-hook transcription factor
chr2_-_26604267	0.456	ENSMUST00000028286.5	Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr7_-_118995211	0.456	ENSMUST00000008878.8	Gprc5b	G protein-coupled receptor, family C, group 5, member B
chr11_-_115612491	0.454	ENSMUST00000106507.2	Mif4gd	MIF4G domain containing
chr11_-_3539228	0.451	ENSMUST00000075118.3 ENSMUST00000136243.1 ENSMUST00000170588.1 ENSMUST00000020721.8	Smtn	smoothelin
chr9_-_106887000	0.450	ENSMUST00000055843.7	Rbm15b	RNA binding motif protein 15B
chr6_-_48840988	0.447	ENSMUST00000164733.1	Tmem176b	transmembrane protein 176B
chr1_-_172027251	0.445	ENSMUST00000138714.1	Vangl2	vang-like 2 (van gogh, Drosophila)
chr17_+_28272191	0.445	ENSMUST00000169040.1	Ppard	peroxisome proliferator activator receptor delta
chr6_-_48841098	0.443	ENSMUST00000101429.4	Tmem176b	transmembrane protein 176B
chr2_+_129592914	0.438	ENSMUST00000103203.1	Sirpa	signal-regulatory protein alpha
chr8_+_106510853	0.430	ENSMUST00000080797.6	Cdh3	cadherin 3
chr2_+_32646586	0.424	ENSMUST00000009705.7 ENSMUST00000167841.1	Eng	endoglin
chr9_-_107289847	0.423	ENSMUST00000035194.2	Mapkapk3	mitogen-activated protein kinase-activated protein kinase 3
chr14_-_62454793	0.420	ENSMUST00000128573.1	Gucy1b2	guanylate cyclase 1, soluble, beta 2
chr9_+_59656368	0.420	ENSMUST00000034834.9 ENSMUST00000163694.2	Pkm	pyruvate kinase, muscle
chr4_+_133584355	0.408	ENSMUST00000030661.7	Gpn2	GPN-loop GTPase 2
chr7_-_80232752	0.400	ENSMUST00000065163.8	Cib1	calcium and integrin binding 1 (calmyrin)
chr1_+_133246092	0.398	ENSMUST00000038295.8 ENSMUST00000105082.2	Plekha6	pleckstrin homology domain containing, family A member 6
chr9_-_119977250	0.397	ENSMUST00000035101.7	Csrnp1	cysteine-serine-rich nuclear protein 1
chr9_+_102720287	0.396	ENSMUST00000130602.1	Amotl2	angiomotin-like 2
chr12_-_112673944	0.389	ENSMUST00000130342.1	Akt1	thymoma viral proto-oncogene 1
chr2_+_153065988	0.381	ENSMUST00000129377.1 ENSMUST00000109800.1	Ccm2l	cerebral cavernous malformation 2-like
chr19_+_18713192	0.378	ENSMUST00000062753.2	D030056L22Rik	RIKEN cDNA D030056L22 gene
chr10_+_96136603	0.378	ENSMUST00000074615.6	Gm5426	predicted pseudogene 5426
chr1_-_5019342	0.371	ENSMUST00000002533.8	Rgs20	regulator of G-protein signaling 20
chr2_+_38339258	0.367	ENSMUST00000143783.2	Lhx2	LIM homeobox protein 2
chr9_-_109849440	0.365	ENSMUST00000112022.2	Camp	cathelicidin antimicrobial peptide
chr14_+_54259227	0.360	ENSMUST00000041197.7	Abhd4	abhydrolase domain containing 4
chr2_-_180225812	0.358	ENSMUST00000015791.5	Lama5	laminin, alpha 5
chr1_-_172027269	0.349	ENSMUST00000027837.6 ENSMUST00000111264.1	Vangl2	vang-like 2 (van gogh, Drosophila)
chr3_-_63851251	0.347	ENSMUST00000162269.2 ENSMUST00000159676.2 ENSMUST00000175947.1	Plch1	phospholipase C, eta 1
chr14_+_65971164	0.346	ENSMUST00000144619.1	Clu	clusterin
chr7_-_127890918	0.345	ENSMUST00000121394.1	Prss53	protease, serine, 53
chrX_+_136270302	0.344	ENSMUST00000113112.1	Ngfrap1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr3_-_104818539	0.343	ENSMUST00000106774.1 ENSMUST00000106775.1 ENSMUST00000166979.1 ENSMUST00000136148.1	Mov10	Moloney leukemia virus 10
chr4_-_91372028	0.343	ENSMUST00000107110.1 ENSMUST00000008633.8 ENSMUST00000107118.1	Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_+_52268337	0.339	ENSMUST00000053764.5	Foxo1	forkhead box O1
chr15_+_74563738	0.337	ENSMUST00000170845.1	Bai1	brain-specific angiogenesis inhibitor 1
chr3_+_89245952	0.335	ENSMUST00000040888.5	Krtcap2	keratinocyte associated protein 2
chr5_-_137502402	0.335	ENSMUST00000111035.1 ENSMUST00000031728.4	Pop7	processing of precursor 7, ribonuclease P family, (S. cerevisiae)
chr6_+_82402475	0.333	ENSMUST00000032122.8	Tacr1	tachykinin receptor 1
chr2_-_25470031	0.332	ENSMUST00000114251.1	Ptgds	prostaglandin D2 synthase (brain)
chr19_+_18713225	0.331	ENSMUST00000055792.7	D030056L22Rik	RIKEN cDNA D030056L22 gene
chr4_+_15265798	0.329	ENSMUST00000062684.8	Tmem64	transmembrane protein 64
chr14_+_62292475	0.329	ENSMUST00000166879.1	Rnaseh2b	ribonuclease H2, subunit B
chr11_-_5898771	0.329	ENSMUST00000102921.3	Myl7	myosin, light polypeptide 7, regulatory
chr9_+_69453620	0.328	ENSMUST00000034756.8 ENSMUST00000123470.1	Anxa2	annexin A2
chr13_-_34994103	0.327	ENSMUST00000171258.1 ENSMUST00000170989.1 ENSMUST00000021854.6 ENSMUST00000110251.2 ENSMUST00000167036.1 ENSMUST00000171229.1 ENSMUST00000178421.1	Eci2	enoyl-Coenzyme A delta isomerase 2
chr5_+_31613939	0.323	ENSMUST00000031024.7	Mrpl33	mitochondrial ribosomal protein L33
chr2_-_26257554	0.320	ENSMUST00000137586.2	C030048H21Rik	RIKEN cDNA C030048H21 gene
chr5_+_24426831	0.320	ENSMUST00000155598.1	Slc4a2	solute carrier family 4 (anion exchanger), member 2
chr3_-_89393294	0.319	ENSMUST00000142119.1 ENSMUST00000029677.8 ENSMUST00000148361.1	Zbtb7b	zinc finger and BTB domain containing 7B
chr3_+_107896247	0.316	ENSMUST00000169365.1	Gstm5	glutathione S-transferase, mu 5
chr12_-_112674193	0.311	ENSMUST00000001780.3	Akt1	thymoma viral proto-oncogene 1
chr4_-_129239165	0.305	ENSMUST00000097873.3	C77080	expressed sequence C77080
chr4_-_91371946	0.302	ENSMUST00000176362.1	Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr6_+_28423539	0.301	ENSMUST00000020717.5 ENSMUST00000169841.1	Arf5	ADP-ribosylation factor 5
chr9_+_44773191	0.299	ENSMUST00000147559.1	Ift46	intraflagellar transport 46
chr12_-_31950535	0.296	ENSMUST00000172314.2	Hbp1	high mobility group box transcription factor 1
chr3_+_94693556	0.294	ENSMUST00000090848.3 ENSMUST00000173981.1 ENSMUST00000173849.1 ENSMUST00000174223.1	Selenbp2	selenium binding protein 2
chr1_+_92910758	0.293	ENSMUST00000027487.8	Rnpepl1	arginyl aminopeptidase (aminopeptidase B)-like 1
chr7_-_80232556	0.293	ENSMUST00000071457.5	Cib1	calcium and integrin binding 1 (calmyrin)
chr2_-_118762607	0.292	ENSMUST00000059997.8	A430105I19Rik	RIKEN cDNA A430105I19 gene
chr17_+_71673255	0.292	ENSMUST00000097284.3	Fam179a	family with sequence similarity 179, member A
chr9_+_69454066	0.291	ENSMUST00000134907.1	Anxa2	annexin A2
chr5_-_125058367	0.287	ENSMUST00000134404.1	Ncor2	nuclear receptor co-repressor 2
chr3_+_122245625	0.286	ENSMUST00000178826.1	Gclm	glutamate-cysteine ligase, modifier subunit
chr8_-_64693027	0.285	ENSMUST00000048967.7	Cpe	carboxypeptidase E
chr7_+_82335732	0.282	ENSMUST00000173287.1	Adamtsl3	ADAMTS-like 3
chr13_-_3918157	0.278	ENSMUST00000091853.4	Net1	neuroepithelial cell transforming gene 1
chr4_-_9643638	0.278	ENSMUST00000108333.1 ENSMUST00000108334.1 ENSMUST00000108335.1 ENSMUST00000152526.1 ENSMUST00000103004.3	Asph	aspartate-beta-hydroxylase
chr10_+_59879617	0.277	ENSMUST00000142819.1 ENSMUST00000020309.6	Dnajb12	DnaJ (Hsp40) homolog, subfamily B, member 12
chr14_-_55591077	0.276	ENSMUST00000161807.1 ENSMUST00000111378.3 ENSMUST00000159687.1	Psme2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr11_+_59202480	0.274	ENSMUST00000108786.1 ENSMUST00000108787.2 ENSMUST00000045697.5 ENSMUST00000108785.1 ENSMUST00000108784.3	Mrpl55	mitochondrial ribosomal protein L55
chr15_-_94404258	0.273	ENSMUST00000035342.4 ENSMUST00000155907.1	Adamts20	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
chr14_+_65971049	0.269	ENSMUST00000128539.1	Clu	clusterin
chr16_+_91406235	0.261	ENSMUST00000023691.5	Il10rb	interleukin 10 receptor, beta
chr3_+_121426495	0.259	ENSMUST00000029773.8	Cnn3	calponin 3, acidic
chr3_-_63964659	0.257	ENSMUST00000161659.1	Slc33a1	solute carrier family 33 (acetyl-CoA transporter), member 1
chr9_-_71163224	0.256	ENSMUST00000074465.2	Aqp9	aquaporin 9
chr14_+_65970610	0.254	ENSMUST00000127387.1	Clu	clusterin
chr14_+_70530819	0.252	ENSMUST00000047331.6	Lgi3	leucine-rich repeat LGI family, member 3
chr12_-_80132802	0.250	ENSMUST00000180643.1	2310015A10Rik	RIKEN cDNA 2310015A10 gene
chr19_-_46045194	0.248	ENSMUST00000156585.1 ENSMUST00000152946.1	Ldb1	LIM domain binding 1
chrX_+_136270253	0.248	ENSMUST00000178632.1 ENSMUST00000053540.4	Ngfrap1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr10_+_128337761	0.247	ENSMUST00000005826.7	Cs	citrate synthase
chr4_+_118429701	0.247	ENSMUST00000067896.3	Elovl1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr17_+_27556613	0.246	ENSMUST00000117600.1 ENSMUST00000114888.3	Hmga1	high mobility group AT-hook 1
chr2_-_26122769	0.246	ENSMUST00000140993.1 ENSMUST00000028300.5	Nacc2	nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr6_-_115251839	0.246	ENSMUST00000032462.6	Timp4	tissue inhibitor of metalloproteinase 4
chr14_+_65970804	0.244	ENSMUST00000138191.1	Clu	clusterin
chr6_+_83142387	0.242	ENSMUST00000130622.1 ENSMUST00000129316.1	Rtkn	rhotekin
chr2_+_85136355	0.242	ENSMUST00000057019.7	Aplnr	apelin receptor

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.8	GO:1903609	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.7	2.2	GO:0090274	positive regulation of somatostatin secretion(GO:0090274)
0.7	3.0	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.6	2.4	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.5	1.6	GO:0072180	mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.5	3.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.5	1.5	GO:0071918	urea transmembrane transport(GO:0071918)
0.5	1.4	GO:0071579	regulation of zinc ion transport(GO:0071579)
0.4	4.3	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4	1.8	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.3	0.9	GO:1904020	regulation of G-protein coupled receptor internalization(GO:1904020)
0.3	1.6	GO:0045218	zonula adherens maintenance(GO:0045218)
0.3	0.8	GO:0060489	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3	0.8	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.3	2.3	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2	1.0	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2	1.6	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	0.7	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.2	0.6	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2	1.1	GO:1902998	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2	1.1	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.2	1.1	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.2	1.1	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
0.2	1.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.2	0.2	GO:1903977	positive regulation of glial cell migration(GO:1903977)
0.2	0.7	GO:0060709	glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2	0.7	GO:2000256	endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.2	1.0	GO:0097473	cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2	0.5	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2	0.8	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.2	2.6	GO:0060134	prepulse inhibition(GO:0060134)
0.1	0.9	GO:0070314	G1 to G0 transition(GO:0070314)
0.1	1.3	GO:1990845	adaptive thermogenesis(GO:1990845)
0.1	0.4	GO:1905072	detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.1	0.5	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.1	0.9	GO:0046549	phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549)
0.1	0.5	GO:0051933	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1	0.9	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.1	0.4	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.1	0.5	GO:0046210	nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1	0.5	GO:0006982	response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.1	0.5	GO:0043973	histone H3-K4 acetylation(GO:0043973)
0.1	1.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1	0.3	GO:0046878	operant conditioning(GO:0035106) sperm ejaculation(GO:0042713) positive regulation of saliva secretion(GO:0046878)
0.1	0.2	GO:0071351	interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.1	0.3	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	1.9	GO:0032060	bleb assembly(GO:0032060)
0.1	0.3	GO:0030070	insulin processing(GO:0030070)
0.1	0.2	GO:0003195	tricuspid valve formation(GO:0003195)
0.1	0.3	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1	0.7	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.1	0.8	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	0.2	GO:0002030	inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.1	0.2	GO:0006553	lysine metabolic process(GO:0006553)
0.1	1.2	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1	0.6	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	0.2	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.1	0.9	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.1	0.3	GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1	1.3	GO:0014823	response to activity(GO:0014823)
0.1	0.3	GO:0033522	histone H2A ubiquitination(GO:0033522) histone H2A monoubiquitination(GO:0035518)
0.1	0.4	GO:0044351	macropinocytosis(GO:0044351)
0.1	0.4	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	0.2	GO:1901228	positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.1	0.5	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.1	0.2	GO:0045004	DNA replication proofreading(GO:0045004)
0.1	0.2	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.1	0.7	GO:0061032	visceral serous pericardium development(GO:0061032)
0.1	0.3	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1	0.7	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	0.2	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1	0.9	GO:0046697	decidualization(GO:0046697)
0.1	0.3	GO:0071455	response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455)
0.1	1.4	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1	0.5	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.3	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0	2.8	GO:0048747	muscle fiber development(GO:0048747)
0.0	0.1	GO:0070488	neutrophil aggregation(GO:0070488)
0.0	2.1	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:0019401	alditol biosynthetic process(GO:0019401)
0.0	1.2	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.2	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.1	GO:0002432	granuloma formation(GO:0002432)
0.0	0.5	GO:0035336	cardiolipin metabolic process(GO:0032048) long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0	0.4	GO:0006691	leukotriene metabolic process(GO:0006691)
0.0	0.3	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.0	0.4	GO:0051852	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0	0.2	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.8	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.5	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.3	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.3	GO:0015791	polyol transport(GO:0015791) response to mercury ion(GO:0046689)
0.0	0.2	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.0	0.5	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	1.5	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.1	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0	0.9	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.3	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	0.2	GO:1905049	negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.2	GO:0060591	chondroblast differentiation(GO:0060591)
0.0	0.2	GO:0070166	enamel mineralization(GO:0070166)
0.0	0.3	GO:1902913	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0	0.2	GO:0015675	nickel cation transport(GO:0015675)
0.0	0.4	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.3	GO:0051451	myoblast migration(GO:0051451)
0.0	0.5	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866)
0.0	0.2	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.2	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
0.0	0.2	GO:1905146	lysosomal protein catabolic process(GO:1905146)
0.0	0.4	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.0	0.6	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.3	GO:0018195	peptidyl-arginine modification(GO:0018195)
0.0	0.2	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.3	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.7	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.2	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0060467	negative regulation of fertilization(GO:0060467)
0.0	0.2	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.5	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0	0.1	GO:0060290	transdifferentiation(GO:0060290)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.2	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.3	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.8	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0031424	keratinization(GO:0031424)
0.0	0.1	GO:0015862	uridine transport(GO:0015862)
0.0	0.1	GO:0036506	maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0	0.5	GO:0010667	negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.3	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.1	GO:0032439	regulation of cholesterol esterification(GO:0010872) endosome localization(GO:0032439) regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:2000319	protein oxidation(GO:0018158) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0	0.1	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.1	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.0	0.1	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.0	0.5	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.0	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.0	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.0	GO:0033580	protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.0	0.1	GO:0046654	'de novo' IMP biosynthetic process(GO:0006189) tetrahydrofolate biosynthetic process(GO:0046654)
0.0	0.4	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.2	GO:0042311	vasodilation(GO:0042311)
0.0	0.1	GO:0090272	negative regulation of fibroblast growth factor production(GO:0090272)
0.0	0.3	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.0	0.1	GO:0006560	proline metabolic process(GO:0006560)
0.0	0.2	GO:0034308	primary alcohol metabolic process(GO:0034308)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.7	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.2	GO:2001224	positive regulation of neuron migration(GO:2001224)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:0071953	elastic fiber(GO:0071953)
0.5	1.8	GO:0045098	type III intermediate filament(GO:0045098)
0.4	4.8	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2	0.6	GO:1990667	PCSK9-AnxA2 complex(GO:1990667)
0.2	0.6	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.2	0.8	GO:0060187	cell pole(GO:0060187)
0.2	1.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.1	1.6	GO:0005915	zonula adherens(GO:0005915)
0.1	0.6	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.1	0.8	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.1	3.7	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.1	0.3	GO:0017109	glutamate-cysteine ligase complex(GO:0017109)
0.1	0.3	GO:0030934	collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1	0.4	GO:0043259	laminin-10 complex(GO:0043259)
0.1	1.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	0.5	GO:0008278	cohesin complex(GO:0008278)
0.1	1.2	GO:0031045	dense core granule(GO:0031045)
0.1	0.5	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	0.8	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	0.8	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	0.2	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.1	0.3	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	1.5	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	4.2	GO:0005604	basement membrane(GO:0005604)
0.0	0.7	GO:0032433	filopodium tip(GO:0032433)
0.0	0.2	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.0	0.7	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.2	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.4	GO:0042581	specific granule(GO:0042581)
0.0	0.5	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.3	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0001533	cornified envelope(GO:0001533)
0.0	0.7	GO:0001741	XY body(GO:0001741)
0.0	0.2	GO:0042825	TAP complex(GO:0042825)
0.0	0.3	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.9	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.2	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	2.5	GO:0042383	sarcolemma(GO:0042383)
0.0	0.5	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.8	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	1.1	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.3	GO:0031672	A band(GO:0031672)
0.0	0.3	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	1.0	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	1.8	GO:0005911	cell-cell junction(GO:0005911)
0.0	1.4	GO:0043195	terminal bouton(GO:0043195)
0.0	0.7	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.5	GO:0005581	collagen trimer(GO:0005581)
0.0	1.9	GO:0005925	focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.8	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
0.8	2.4	GO:0035939	microsatellite binding(GO:0035939)
0.7	4.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.5	1.8	GO:1990254	keratin filament binding(GO:1990254)
0.3	1.4	GO:0050436	microfibril binding(GO:0050436)
0.3	1.3	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.3	1.7	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.3	3.4	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2	0.9	GO:0004921	interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2	0.8	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.2	2.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	1.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.2	0.5	GO:0030156	benzodiazepine receptor binding(GO:0030156)
0.2	0.5	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2	0.7	GO:0008131	primary amine oxidase activity(GO:0008131)
0.2	0.6	GO:0004859	phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.6	GO:0004074	biliverdin reductase activity(GO:0004074)
0.1	0.4	GO:0016501	prostacyclin receptor activity(GO:0016501)
0.1	1.4	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	0.4	GO:0004743	pyruvate kinase activity(GO:0004743)
0.1	0.7	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1	1.6	GO:0070097	delta-catenin binding(GO:0070097)
0.1	1.2	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1	0.8	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1	2.0	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.8	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.5	GO:0016708	nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.1	1.3	GO:0008430	selenium binding(GO:0008430)
0.1	0.3	GO:0004357	glutamate-cysteine ligase activity(GO:0004357)
0.1	2.6	GO:0030506	ankyrin binding(GO:0030506)
0.1	0.7	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.7	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.4	GO:0005534	galactose binding(GO:0005534)
0.1	0.2	GO:0019966	interleukin-1 binding(GO:0019966)
0.1	0.7	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.5	GO:0051185	coenzyme transporter activity(GO:0051185)
0.1	2.8	GO:0005504	fatty acid binding(GO:0005504)
0.1	0.5	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	1.6	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	0.2	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	1.1	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.1	0.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.6	GO:0038191	neuropilin binding(GO:0038191)
0.1	0.5	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.9	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.5	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	2.6	GO:0008528	G-protein coupled peptide receptor activity(GO:0008528)
0.0	1.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.5	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.4	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	1.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.3	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.2	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0	0.2	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.2	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.8	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.7	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.2	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.2	GO:0045545	syndecan binding(GO:0045545)
0.0	0.5	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.5	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.0	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.0	0.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.2	GO:0015099	nickel cation transmembrane transporter activity(GO:0015099)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.2	GO:0036122	BMP binding(GO:0036122)
0.0	0.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.3	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.3	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	1.7	GO:0019003	GDP binding(GO:0019003)
0.0	0.5	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0019841	retinol binding(GO:0019841)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0005118	sevenless binding(GO:0005118)
0.0	0.3	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.2	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.0	0.6	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.4	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0	0.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0098631	protein binding involved in cell adhesion(GO:0098631)
0.0	0.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.6	GO:0005158	insulin receptor binding(GO:0005158)
0.0	1.1	GO:0005080	protein kinase C binding(GO:0005080)
0.0	1.2	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	1.6	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.1	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	0.3	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0015217	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0	1.0	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.1	GO:0017166	vinculin binding(GO:0017166)
0.0	0.0	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.0	2.3	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.3	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.0	GO:0016174	NAD(P)H oxidase activity(GO:0016174)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.9	PID_WNT_CANONICAL_PATHWAY	Canonical Wnt signaling pathway
0.1	2.9	PID_HNF3B_PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	2.2	NABA_BASEMENT_MEMBRANES	Genes encoding structural components of basement membranes
0.1	1.0	ST_INTERLEUKIN_4_PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	0.4	ST_PAC1_RECEPTOR_PATHWAY	PAC1 Receptor Pathway
0.1	0.7	PID_INTEGRIN2_PATHWAY	Beta2 integrin cell surface interactions
0.0	0.4	PID_ALK1_PATHWAY	ALK1 signaling events
0.0	0.6	ST_STAT3_PATHWAY	STAT3 Pathway
0.0	2.0	PID_AURORA_B_PATHWAY	Aurora B signaling
0.0	2.8	PID_HES_HEY_PATHWAY	Notch-mediated HES/HEY network
0.0	0.7	PID_INTEGRIN_CS_PATHWAY	Integrin family cell surface interactions
0.0	0.8	PID_HIF1A_PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	2.4	PID_EPHB_FWD_PATHWAY	EPHB forward signaling
0.0	5.1	NABA_ECM_REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.2	SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.9	NABA_COLLAGENS	Genes encoding collagen proteins
0.0	0.8	PID_RET_PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	3.0	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.2	PID_ATF2_PATHWAY	ATF-2 transcription factor network
0.0	1.5	PID_MYC_REPRESS_PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	2.8	NABA_ECM_GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.5	PID_IL4_2PATHWAY	IL4-mediated signaling events
0.0	1.0	PID_ECADHERIN_STABILIZATION_PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.2	SA_MMP_CYTOKINE_CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.5	PID_P38_MK2_PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	PID_S1P_S1P1_PATHWAY	S1P1 pathway
0.0	0.4	ST_G_ALPHA_I_PATHWAY	G alpha i Pathway
0.0	0.4	PID_PS1_PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.3	PID_PI3KCI_AKT_PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.3	PID_MYC_PATHWAY	C-MYC pathway
0.0	0.5	PID_NOTCH_PATHWAY	Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.4	REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.7	REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	4.2	REACTOME_GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	0.2	REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	2.5	REACTOME_HS_GAG_DEGRADATION	Genes involved in HS-GAG degradation
0.1	1.7	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	2.6	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.9	REACTOME_AMINE_DERIVED_HORMONES	Genes involved in Amine-derived hormones
0.1	1.8	REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.2	REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.5	REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	1.2	REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	0.5	REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	0.8	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	0.6	REACTOME_IL_6_SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.7	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.0	REACTOME_ACTIVATION_OF_GENES_BY_ATF4	Genes involved in Activation of Genes by ATF4
0.0	1.1	REACTOME_GLUTATHIONE_CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.8	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.6	REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.7	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.7	REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.8	REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	2.6	REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	2.7	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.3	REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.5	REACTOME_P38MAPK_EVENTS	Genes involved in p38MAPK events
0.0	1.0	REACTOME_TIGHT_JUNCTION_INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.6	REACTOME_METABOLISM_OF_PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.9	REACTOME_GLYCOSPHINGOLIPID_METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.5	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.2	REACTOME_PYRIMIDINE_CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	1.5	REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.4	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.6	REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.6	REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.2	REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.1	REACTOME_PURINE_CATABOLISM	Genes involved in Purine catabolism
0.0	0.4	REACTOME_CELL_CELL_JUNCTION_ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.4	REACTOME_SIGNALING_BY_HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.4	REACTOME_SYNTHESIS_OF_PA	Genes involved in Synthesis of PA
0.0	0.8	REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.9	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.2	REACTOME_SIGNAL_ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING	Genes involved in Insulin Synthesis and Processing

---