Motif ID: Nhlh1

Z-value: 0.979


Transcription factors associated with Nhlh1:

Gene SymbolEntrez IDGene Name
Nhlh1 ENSMUSG00000051251.3 Nhlh1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nhlh1mm10_v2_chr1_-_172057573_172057598-0.644.5e-03Click!


Activity profile for motif Nhlh1.

activity profile for motif Nhlh1


Sorted Z-values histogram for motif Nhlh1

Sorted Z-values for motif Nhlh1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nhlh1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_91269759 3.477 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr4_-_64046925 2.915 ENSMUST00000107377.3
Tnc
tenascin C
chr10_-_27616895 2.564 ENSMUST00000092639.5
Lama2
laminin, alpha 2
chr4_+_104367549 1.846 ENSMUST00000106830.2
Dab1
disabled 1
chr5_+_117841839 1.743 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr2_+_70562007 1.557 ENSMUST00000094934.4
Gad1
glutamate decarboxylase 1
chr14_+_119138415 1.486 ENSMUST00000065904.3
Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr15_-_71727815 1.438 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr6_-_148444336 1.400 ENSMUST00000060095.8
ENSMUST00000100772.3
Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr12_+_82616885 1.337 ENSMUST00000161801.1
Rgs6
regulator of G-protein signaling 6
chr2_-_162661075 1.335 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
Ptprt



protein tyrosine phosphatase, receptor type, T



chrX_-_162643575 1.277 ENSMUST00000101102.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr5_+_147188678 1.223 ENSMUST00000065382.5
Gsx1
GS homeobox 1
chrX_-_162643629 1.114 ENSMUST00000112334.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr6_-_101377897 1.114 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr5_-_139130159 1.088 ENSMUST00000129851.1
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr10_-_121311034 1.050 ENSMUST00000064107.5
Tbc1d30
TBC1 domain family, member 30
chr11_+_50602072 1.025 ENSMUST00000040523.8
Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr1_-_22805994 1.005 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr1_-_134955847 0.998 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr12_+_81026800 0.985 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
Smoc1


SPARC related modular calcium binding 1


chr2_+_25395866 0.978 ENSMUST00000028328.2
Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr5_-_110343009 0.964 ENSMUST00000058016.9
ENSMUST00000112478.3
P2rx2

purinergic receptor P2X, ligand-gated ion channel, 2

chr2_+_70562147 0.950 ENSMUST00000148210.1
Gad1
glutamate decarboxylase 1
chr2_-_163918683 0.929 ENSMUST00000044734.2
Rims4
regulating synaptic membrane exocytosis 4
chr12_+_26469204 0.912 ENSMUST00000020969.3
Cmpk2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr3_-_84304762 0.911 ENSMUST00000107692.1
Trim2
tripartite motif-containing 2
chr7_-_4844665 0.894 ENSMUST00000066041.5
ENSMUST00000172377.1
Shisa7

shisa homolog 7 (Xenopus laevis)

chr13_-_34652671 0.876 ENSMUST00000053459.7
Pxdc1
PX domain containing 1
chr12_-_76709997 0.874 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr11_-_72489904 0.859 ENSMUST00000045303.3
Spns2
spinster homolog 2
chr1_-_3671498 0.846 ENSMUST00000070533.4
Xkr4
X Kell blood group precursor related family member 4
chr15_-_44788016 0.823 ENSMUST00000090057.4
ENSMUST00000110269.1
Sybu

syntabulin (syntaxin-interacting)

chr13_-_117025505 0.821 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr6_-_29179584 0.810 ENSMUST00000159200.1
Prrt4
proline-rich transmembrane protein 4
chr16_-_22439570 0.799 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr15_+_81936753 0.796 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr1_-_134955908 0.794 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr2_+_158666690 0.793 ENSMUST00000103116.3
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr7_+_46396439 0.792 ENSMUST00000025202.6
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr4_+_141368116 0.791 ENSMUST00000006380.4
Fam131c
family with sequence similarity 131, member C
chr2_+_70562854 0.783 ENSMUST00000130998.1
Gad1
glutamate decarboxylase 1
chr7_+_73740277 0.783 ENSMUST00000107456.2
Fam174b
family with sequence similarity 174, member B
chr11_-_67922136 0.781 ENSMUST00000021288.3
ENSMUST00000108677.1
Usp43

ubiquitin specific peptidase 43

chr2_-_36105271 0.778 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr15_+_81936911 0.776 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr9_-_75611308 0.770 ENSMUST00000064433.3
Tmod2
tropomodulin 2
chr16_+_72663143 0.758 ENSMUST00000023600.7
Robo1
roundabout homolog 1 (Drosophila)
chr8_+_12385769 0.758 ENSMUST00000080795.8
Gm5607
predicted gene 5607
chr8_+_125995102 0.742 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr16_+_7069825 0.739 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_-_39190687 0.732 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai

suppressor of cancer cell invasion

chr8_+_40862379 0.724 ENSMUST00000098816.3
ENSMUST00000057784.8
ENSMUST00000141505.1
Slc7a2


solute carrier family 7 (cationic amino acid transporter, y+ system), member 2


chr10_+_86021961 0.685 ENSMUST00000130320.1
Fbxo7
F-box protein 7
chr3_+_101377074 0.683 ENSMUST00000043983.5
Igsf3
immunoglobulin superfamily, member 3
chr14_-_102982630 0.681 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr2_-_25319095 0.677 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr12_-_79007276 0.675 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr2_-_181156993 0.672 ENSMUST00000055990.7
Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr13_+_24638636 0.669 ENSMUST00000110384.2
ENSMUST00000058009.9
ENSMUST00000038477.6
Fam65b


family with sequence similarity 65, member B


chr10_+_112271123 0.659 ENSMUST00000092175.2
Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chrX_+_159627265 0.652 ENSMUST00000112456.2
Sh3kbp1
SH3-domain kinase binding protein 1
chr2_+_158667119 0.649 ENSMUST00000045503.4
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr7_-_19166119 0.643 ENSMUST00000094790.3
Gipr
gastric inhibitory polypeptide receptor
chrX_-_95196450 0.641 ENSMUST00000181987.1
Arhgef9
CDC42 guanine nucleotide exchange factor (GEF) 9
chr11_-_116110211 0.639 ENSMUST00000106441.1
ENSMUST00000021120.5
Trim47

tripartite motif-containing 47

chr6_-_53068562 0.637 ENSMUST00000074541.5
Jazf1
JAZF zinc finger 1
chr15_-_83724979 0.637 ENSMUST00000171496.1
ENSMUST00000043634.5
ENSMUST00000076060.5
ENSMUST00000016907.7
Scube1



signal peptide, CUB domain, EGF-like 1



chr4_+_130308595 0.635 ENSMUST00000070532.7
Fabp3
fatty acid binding protein 3, muscle and heart
chr14_-_118925314 0.634 ENSMUST00000004055.8
Dzip1
DAZ interacting protein 1
chr2_-_181135103 0.628 ENSMUST00000149964.2
ENSMUST00000103050.3
ENSMUST00000081528.6
ENSMUST00000049792.8
ENSMUST00000103048.3
ENSMUST00000103047.3
ENSMUST00000129073.1
ENSMUST00000144592.1
ENSMUST00000139458.1
ENSMUST00000154164.1
ENSMUST00000123336.1
ENSMUST00000129361.1
ENSMUST00000103051.2
Kcnq2












potassium voltage-gated channel, subfamily Q, member 2












chr11_+_42419729 0.628 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr4_+_137707458 0.626 ENSMUST00000097837.4
Rap1gap
Rap1 GTPase-activating protein
chr6_+_91212799 0.624 ENSMUST00000153364.1
ENSMUST00000132021.1
ENSMUST00000134974.1
Fbln2


fibulin 2


chr16_-_22439719 0.621 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr4_-_133498538 0.618 ENSMUST00000125541.1
Trnp1
TMF1-regulated nuclear protein 1
chr8_+_72646679 0.618 ENSMUST00000161386.1
ENSMUST00000093427.4
Nwd1

NACHT and WD repeat domain containing 1

chr13_+_109260481 0.613 ENSMUST00000153234.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr14_+_45219993 0.609 ENSMUST00000146150.1
Gpr137c
G protein-coupled receptor 137C
chr11_-_101785252 0.608 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr9_-_39604124 0.607 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chr13_-_76385028 0.607 ENSMUST00000099365.1
Gm10760
predicted gene 10760
chr3_+_89520152 0.603 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr9_-_53706211 0.593 ENSMUST00000068449.3
Rab39
RAB39, member RAS oncogene family
chrX_-_57338598 0.591 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr10_+_3366125 0.587 ENSMUST00000043374.5
Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr11_-_50931612 0.586 ENSMUST00000109124.3
Zfp354b
zinc finger protein 354B
chr15_+_81811414 0.581 ENSMUST00000023024.7
Tef
thyrotroph embryonic factor
chr5_+_105415738 0.576 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr8_-_115706994 0.575 ENSMUST00000069009.6
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr7_+_123982799 0.568 ENSMUST00000106437.1
Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chrX_-_16911774 0.567 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr8_+_72646728 0.566 ENSMUST00000161254.1
Nwd1
NACHT and WD repeat domain containing 1
chr3_-_127225847 0.566 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr3_-_36475688 0.565 ENSMUST00000029266.8
Anxa5
annexin A5
chr3_-_54915867 0.563 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr9_-_40346290 0.562 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr2_-_136387929 0.561 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr9_+_107935876 0.559 ENSMUST00000035700.8
Camkv
CaM kinase-like vesicle-associated
chr14_+_68083853 0.555 ENSMUST00000022639.7
Nefl
neurofilament, light polypeptide
chr9_-_89622986 0.551 ENSMUST00000044491.6
AF529169
cDNA sequence AF529169
chr5_+_17574726 0.550 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr9_-_57836706 0.550 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr11_-_120047070 0.549 ENSMUST00000064307.3
Aatk
apoptosis-associated tyrosine kinase
chr4_+_53440388 0.545 ENSMUST00000102911.3
ENSMUST00000107646.2
Slc44a1

solute carrier family 44, member 1

chr15_-_66500857 0.543 ENSMUST00000023006.6
Lrrc6
leucine rich repeat containing 6 (testis)
chr12_+_105336922 0.542 ENSMUST00000180503.1
2810011L19Rik
RIKEN cDNA 2810011L19 gene
chr6_-_126166726 0.541 ENSMUST00000112244.2
ENSMUST00000050484.7
Ntf3

neurotrophin 3

chr12_-_72070991 0.539 ENSMUST00000050649.4
Gpr135
G protein-coupled receptor 135
chr11_+_103171081 0.539 ENSMUST00000042286.5
Fmnl1
formin-like 1
chr4_+_42917234 0.537 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr17_+_5492558 0.535 ENSMUST00000089185.4
Zdhhc14
zinc finger, DHHC domain containing 14
chr16_-_17576631 0.535 ENSMUST00000164545.1
ENSMUST00000164490.1
ENSMUST00000172164.1
Slc7a4


solute carrier family 7 (cationic amino acid transporter, y+ system), member 4


chr9_+_67840386 0.535 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chr1_-_158356258 0.535 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr11_+_97450136 0.534 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr13_+_16011851 0.530 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr3_-_127225917 0.530 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr3_-_148989316 0.530 ENSMUST00000098518.2
Lphn2
latrophilin 2
chr9_-_95750335 0.529 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr11_-_120047144 0.529 ENSMUST00000103020.1
Aatk
apoptosis-associated tyrosine kinase
chr4_+_119814495 0.528 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr17_-_6477102 0.522 ENSMUST00000167717.2
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr2_-_5714490 0.520 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr1_-_130715734 0.519 ENSMUST00000066863.6
ENSMUST00000050406.4
Pfkfb2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr15_-_77956658 0.515 ENSMUST00000117725.1
ENSMUST00000016696.6
Foxred2

FAD-dependent oxidoreductase domain containing 2

chr7_+_57591147 0.515 ENSMUST00000039697.7
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr1_-_190978954 0.515 ENSMUST00000047409.6
Vash2
vasohibin 2
chr4_-_8239034 0.515 ENSMUST00000066674.7
Car8
carbonic anhydrase 8
chr8_-_105295934 0.514 ENSMUST00000057855.3
Exoc3l
exocyst complex component 3-like
chr9_+_51765325 0.508 ENSMUST00000065496.5
Arhgap20
Rho GTPase activating protein 20
chr5_-_18360384 0.507 ENSMUST00000074694.5
Gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr17_-_6827990 0.505 ENSMUST00000181895.1
Gm2885
predicted gene 2885
chr18_+_67088287 0.505 ENSMUST00000025402.7
Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr4_-_151108244 0.503 ENSMUST00000131948.1
Camta1
calmodulin binding transcription activator 1
chr14_-_65425453 0.503 ENSMUST00000059339.5
Pnoc
prepronociceptin
chr1_-_190979280 0.502 ENSMUST00000166139.1
Vash2
vasohibin 2
chr11_-_32222233 0.500 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr19_+_29251748 0.498 ENSMUST00000065796.3
ENSMUST00000025705.6
Jak2

Janus kinase 2

chr15_-_72034202 0.497 ENSMUST00000159993.1
Col22a1
collagen, type XXII, alpha 1
chr19_+_6399857 0.493 ENSMUST00000146601.1
ENSMUST00000150713.1
Rasgrp2

RAS, guanyl releasing protein 2

chr10_-_30803075 0.492 ENSMUST00000068567.4
Ncoa7
nuclear receptor coactivator 7
chr10_+_29211637 0.492 ENSMUST00000092627.4
9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr11_+_77216180 0.492 ENSMUST00000037912.5
ENSMUST00000156488.1
Ssh2

slingshot homolog 2 (Drosophila)

chr17_+_48932368 0.491 ENSMUST00000046254.2
Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
chr15_-_58214882 0.487 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr17_-_26201328 0.486 ENSMUST00000025019.2
Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr2_+_25242227 0.481 ENSMUST00000154498.1
Rnf208
ring finger protein 208
chr1_+_75546449 0.480 ENSMUST00000150142.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr1_-_38821215 0.478 ENSMUST00000039612.4
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr15_-_33687840 0.474 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr1_-_39478734 0.471 ENSMUST00000054462.5
Tbc1d8
TBC1 domain family, member 8
chr10_-_53379816 0.469 ENSMUST00000095691.5
Cep85l
centrosomal protein 85-like
chr19_-_29047847 0.469 ENSMUST00000025696.4
Ak3
adenylate kinase 3
chr8_+_105605220 0.465 ENSMUST00000043531.8
Fam65a
family with sequence similarity 65, member A
chr2_-_113217051 0.464 ENSMUST00000080673.5
Ryr3
ryanodine receptor 3
chr11_-_101226414 0.464 ENSMUST00000100417.2
ENSMUST00000107285.1
ENSMUST00000107284.1
Ezh1


enhancer of zeste homolog 1 (Drosophila)


chr11_+_73018986 0.464 ENSMUST00000092937.6
Camkk1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr10_+_98915117 0.462 ENSMUST00000020107.7
Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr11_+_29373618 0.462 ENSMUST00000040182.6
ENSMUST00000109477.1
Ccdc88a

coiled coil domain containing 88A

chr2_-_33371400 0.462 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr4_-_155345696 0.462 ENSMUST00000103178.4
Prkcz
protein kinase C, zeta
chrX_+_136741821 0.461 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr9_-_70657121 0.460 ENSMUST00000049031.5
Fam63b
family with sequence similarity 63, member B
chr3_+_68584154 0.459 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chr17_+_87107621 0.459 ENSMUST00000041369.6
Socs5
suppressor of cytokine signaling 5
chr8_-_29219338 0.459 ENSMUST00000168630.2
Unc5d
unc-5 homolog D (C. elegans)
chr11_-_121388186 0.457 ENSMUST00000106107.2
Rab40b
Rab40b, member RAS oncogene family
chrX_+_134404780 0.457 ENSMUST00000113224.2
ENSMUST00000113226.1
Drp2

dystrophin related protein 2

chr1_-_162859684 0.456 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr1_+_75546522 0.456 ENSMUST00000138814.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr17_-_26201363 0.455 ENSMUST00000121959.1
Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr10_+_81633694 0.453 ENSMUST00000140345.1
ENSMUST00000126323.1
Ankrd24

ankyrin repeat domain 24

chr18_+_34220890 0.452 ENSMUST00000171187.1
Apc
adenomatosis polyposis coli
chr13_-_6648717 0.452 ENSMUST00000021614.7
ENSMUST00000138703.1
Pfkp

phosphofructokinase, platelet

chr3_-_144205165 0.448 ENSMUST00000120539.1
Lmo4
LIM domain only 4
chrX_+_110814390 0.448 ENSMUST00000078229.3
Pou3f4
POU domain, class 3, transcription factor 4
chr7_+_16944645 0.447 ENSMUST00000094807.5
Pnmal2
PNMA-like 2
chrX_+_13071470 0.446 ENSMUST00000169594.2
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr13_-_51567084 0.445 ENSMUST00000021898.5
Shc3
src homology 2 domain-containing transforming protein C3
chr16_-_28929658 0.444 ENSMUST00000100023.1
Mb21d2
Mab-21 domain containing 2
chr12_-_111908040 0.442 ENSMUST00000163747.2
ENSMUST00000054815.7
Ppp1r13b

protein phosphatase 1, regulatory (inhibitor) subunit 13B

chr7_-_31126945 0.437 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr4_+_102760135 0.436 ENSMUST00000066824.7
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr11_-_87359011 0.435 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr15_+_89059712 0.430 ENSMUST00000161372.1
ENSMUST00000162424.1
Panx2

pannexin 2

chr3_-_10440054 0.430 ENSMUST00000099223.4
ENSMUST00000029047.6
Snx16

sorting nexin 16

chr14_+_3412614 0.428 ENSMUST00000170123.1
Gm10409
predicted gene 10409
chr5_-_37717122 0.428 ENSMUST00000094836.4
Stk32b
serine/threonine kinase 32B
chr2_-_148732457 0.426 ENSMUST00000028926.6
Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr14_+_61172966 0.425 ENSMUST00000121091.1
Sacs
sacsin
chr3_-_104511812 0.423 ENSMUST00000046316.6
Lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr2_-_5063996 0.421 ENSMUST00000114996.1
Optn
optineurin
chr8_+_12873793 0.419 ENSMUST00000156560.1
ENSMUST00000095456.3
Mcf2l

mcf.2 transforming sequence-like

chr5_+_138280538 0.418 ENSMUST00000162245.1
ENSMUST00000161691.1
Stag3

stromal antigen 3

chr9_+_103112072 0.414 ENSMUST00000035155.6
Rab6b
RAB6B, member RAS oncogene family
chr17_-_45686120 0.413 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b

chr6_+_124997062 0.413 ENSMUST00000159391.1
Pianp
PILR alpha associated neural protein
chr5_-_66618636 0.412 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr4_+_85205417 0.412 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
Sh3gl2


SH3-domain GRB2-like 2



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.6 1.7 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
0.5 1.6 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.5 3.3 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.4 2.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.4 1.4 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.3 1.0 GO:1900673 olefin metabolic process(GO:1900673)
0.3 1.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 0.9 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.3 1.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.3 0.8 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 1.0 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 0.7 GO:1902022 L-lysine transport(GO:1902022)
0.2 0.2 GO:0018307 enzyme active site formation(GO:0018307)
0.2 0.7 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.2 0.4 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.2 0.8 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.2 1.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.2 0.8 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 0.7 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.2 0.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 0.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 0.7 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 0.5 GO:0070671 response to interleukin-12(GO:0070671)
0.2 0.3 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.2 0.5 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 0.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 0.5 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.2 0.6 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 0.3 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.2 0.9 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.9 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.1 0.9 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.9 GO:0009405 pathogenesis(GO:0009405)
0.1 0.6 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.7 GO:0015871 choline transport(GO:0015871)
0.1 0.3 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.4 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 1.8 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.3 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.1 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.1 1.1 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.4 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.4 GO:0060166 olfactory pit development(GO:0060166)
0.1 1.0 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.6 GO:0015705 iodide transport(GO:0015705)
0.1 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 1.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.6 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 0.4 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.4 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 1.5 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 1.0 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.1 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 0.3 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.7 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.1 0.8 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.5 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.3 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.5 GO:0046541 saliva secretion(GO:0046541)
0.1 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.3 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.4 GO:2000834 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of androgen secretion(GO:2000834) regulation of testosterone secretion(GO:2000843)
0.1 0.6 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 1.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 0.3 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
0.1 0.3 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.3 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.5 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.5 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 0.6 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.6 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.3 GO:0060854 patterning of lymph vessels(GO:0060854)
0.1 0.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.5 GO:1904923 regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.1 0.3 GO:0035672 regulation of cellular pH reduction(GO:0032847) oligopeptide transmembrane transport(GO:0035672)
0.1 0.3 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.1 0.4 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.6 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 1.0 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.6 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 0.5 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.2 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1 0.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.3 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.4 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.2 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.1 0.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.5 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.2 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.2 GO:0071287 cellular response to manganese ion(GO:0071287)
0.1 0.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 1.0 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.3 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1 0.1 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1 0.4 GO:0032596 protein transport into membrane raft(GO:0032596)
0.1 0.4 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.6 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.5 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.3 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 1.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.5 GO:0051014 actin filament severing(GO:0051014)
0.1 0.4 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.1 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.7 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 0.2 GO:1900368 regulation of RNA interference(GO:1900368)
0.1 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.4 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 1.0 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.3 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 0.4 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0030913 paranodal junction assembly(GO:0030913)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298)
0.0 0.2 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0097274 urea homeostasis(GO:0097274)
0.0 0.5 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0030388 fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.3 GO:2000507 response to muscle activity(GO:0014850) positive regulation of energy homeostasis(GO:2000507)
0.0 0.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.6 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.8 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.3 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.8 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.0 0.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 1.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.0 0.3 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.5 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:1904953 regulation of collateral sprouting in absence of injury(GO:0048696) Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.0 0.2 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.6 GO:0001553 luteinization(GO:0001553)
0.0 0.3 GO:0034312 diol biosynthetic process(GO:0034312)
0.0 0.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.1 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0 0.5 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.0 0.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.2 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.6 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.6 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.2 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.8 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 0.1 GO:0042748 circadian sleep/wake cycle, non-REM sleep(GO:0042748)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0046959 habituation(GO:0046959)
0.0 0.3 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.3 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.3 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.5 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.0 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.6 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0097421 liver regeneration(GO:0097421)
0.0 0.2 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.5 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.2 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.4 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.0 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.0 GO:0061110 dense core granule biogenesis(GO:0061110)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.2 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.1 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.2 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.1 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0 0.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.1 GO:0014742 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.2 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.6 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.0 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 1.7 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.0 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 0.0 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 1.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0006544 glycine metabolic process(GO:0006544)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542) positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.0 0.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.3 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.6 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.2 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.5 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.1 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0040016 positive regulation of neutrophil apoptotic process(GO:0033031) positive regulation of myeloid cell apoptotic process(GO:0033034) embryonic cleavage(GO:0040016)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0042711 maternal behavior(GO:0042711)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.7 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 1.0 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.5 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0033005 positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.0 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.0 GO:0032274 gonadotropin secretion(GO:0032274)
0.0 0.1 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.0 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.4 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.0 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.0 0.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.3 0.9 GO:0043512 inhibin A complex(GO:0043512)
0.3 1.2 GO:0044307 dendritic branch(GO:0044307)
0.3 0.8 GO:0000802 transverse filament(GO:0000802)
0.3 1.3 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.3 0.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 0.9 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 0.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 2.9 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.0 GO:0008091 spectrin(GO:0008091)
0.2 1.7 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 3.1 GO:0005605 basal lamina(GO:0005605)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.4 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.8 GO:0071203 WASH complex(GO:0071203)
0.1 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.5 GO:1990037 Lewy body core(GO:1990037)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 3.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 3.4 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.1 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 0.8 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 2.7 GO:0031672 A band(GO:0031672)
0.1 1.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.6 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.2 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 3.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 1.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 1.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0005940 septin ring(GO:0005940)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.6 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 1.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.5 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0002141 stereocilia ankle link(GO:0002141)
0.0 1.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 1.1 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.0 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 3.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0070187 telosome(GO:0070187)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.6 GO:0005776 autophagosome(GO:0005776)
0.0 1.5 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.0 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.0 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 2.0 GO:0045211 postsynaptic membrane(GO:0045211)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.5 3.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.4 2.6 GO:0045545 syndecan binding(GO:0045545)
0.3 1.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.3 0.9 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.3 0.9 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.3 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 0.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.2 0.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 1.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 0.7 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.2 0.7 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 1.0 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 0.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 0.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 0.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.7 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.8 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 1.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.3 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 0.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.0 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.3 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.3 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.2 GO:0051379 epinephrine binding(GO:0051379)
0.1 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 1.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.2 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 1.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.7 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.6 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.5 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.5 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.4 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.2 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.1 0.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) phosphofructokinase activity(GO:0008443)
0.1 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.9 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.1 GO:2001070 starch binding(GO:2001070)
0.0 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.2 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.7 GO:0017046 peptide hormone binding(GO:0017046)
0.0 3.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 7.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 3.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.3 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.4 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.3 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.0 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.0 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0031811 beta-1 adrenergic receptor binding(GO:0031697) G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0008227 G-protein coupled amine receptor activity(GO:0008227)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.0 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.1 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.0 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.5 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.8 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 0.2 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.5 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID_S1P_S1P3_PATHWAY S1P3 pathway
0.0 2.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.7 PID_SHP2_PATHWAY SHP2 signaling
0.0 1.5 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.4 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.3 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 1.3 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.2 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.3 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 0.2 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.2 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.2 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.3 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.1 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.6 PID_MTOR_4PATHWAY mTOR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.2 4.1 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 0.5 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 1.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 0.5 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.3 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 0.1 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 2.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 0.6 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 1.7 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.8 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 0.4 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 2.6 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.5 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.8 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 1.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.4 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 2.4 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 0.3 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 1.2 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 1.3 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.3 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.4 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME_SHC_MEDIATED_SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation