Motif ID: Nr0b1

Z-value: 0.940


Transcription factors associated with Nr0b1:

Gene SymbolEntrez IDGene Name
Nr0b1 ENSMUSG00000025056.4 Nr0b1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr0b1mm10_v2_chrX_+_86191764_86191782-0.341.6e-01Click!


Activity profile for motif Nr0b1.

activity profile for motif Nr0b1


Sorted Z-values histogram for motif Nr0b1

Sorted Z-values for motif Nr0b1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr0b1

PNG image of the network

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Top targets:


Showing 1 to 20 of 80 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_19094594 3.904 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr2_-_54085542 2.808 ENSMUST00000100089.2
 Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr16_-_45844303 2.471 ENSMUST00000036355.6
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr16_-_45844228 2.393 ENSMUST00000076333.5
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr5_-_99037035 2.239 ENSMUST00000031277.6
 Prkg2
protein kinase, cGMP-dependent, type II
chr17_-_70851189 2.128 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr5_-_99037342 2.007 ENSMUST00000161490.1
 Prkg2
protein kinase, cGMP-dependent, type II
chrX_-_48034842 1.739 ENSMUST00000039026.7
 Apln
apelin
chr7_+_79500081 1.607 ENSMUST00000181511.2
ENSMUST00000182937.1
 AI854517

expressed sequence AI854517

chr7_+_79500018 1.553 ENSMUST00000182495.1
ENSMUST00000183043.1
 AI854517

expressed sequence AI854517

chr5_+_30913398 1.420 ENSMUST00000031055.5
 Emilin1
elastin microfibril interfacer 1
chr11_+_102604370 1.355 ENSMUST00000057893.5
 Fzd2
frizzled homolog 2 (Drosophila)
chr2_-_65238625 1.351 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
 Cobll1


Cobl-like 1


chr8_-_105707933 1.253 ENSMUST00000013299.9
 Enkd1
enkurin domain containing 1
chr2_+_30066419 1.186 ENSMUST00000067996.6
 Set
SET nuclear oncogene
chr11_+_94328242 1.182 ENSMUST00000021227.5
 Ankrd40
ankyrin repeat domain 40
chr1_+_42697146 1.145 ENSMUST00000054883.2
 Pou3f3
POU domain, class 3, transcription factor 3
chr14_+_11553523 1.065 ENSMUST00000022264.6
 Ptprg
protein tyrosine phosphatase, receptor type, G
chr2_+_157279065 1.045 ENSMUST00000029171.5
 Rpn2
ribophorin II
chr19_-_46039442 0.966 ENSMUST00000137771.1
 Ldb1
LIM domain binding 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 4.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.6 4.2 GO:2001225 cellular hypotonic response(GO:0071476) regulation of chloride transport(GO:2001225)
0.3 3.9 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.0 2.8 GO:0007050 cell cycle arrest(GO:0007050)
0.1 2.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.6 1.7 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.3 1.4 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.4 GO:0070207 protein homotrimerization(GO:0070207)
0.0 1.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.3 1.1 GO:0072236 DCT cell differentiation(GO:0072069) metanephric loop of Henle development(GO:0072236) metanephric DCT cell differentiation(GO:0072240)
0.2 1.0 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.9 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.9 GO:1901998 toxin transport(GO:1901998)
0.0 0.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 0.6 GO:0036166 phenotypic switching(GO:0036166)
0.2 0.6 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.6 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.5 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.9 GO:0045180 basal cortex(GO:0045180)
0.0 4.0 GO:0031965 nuclear membrane(GO:0031965)
0.1 1.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.2 0.8 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 0.6 GO:0000235 astral microtubule(GO:0000235)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 4.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 2.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 1.4 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.0 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0038132 neuregulin binding(GO:0038132)

Gene overrepresentation in C2:CP category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 1.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.6 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.5 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.2 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.8 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery