ISMARA results: Nr1h2

Motif ID: Nr1h2

Z-value: 1.128

Transcription factors associated with Nr1h2:

Gene Symbol	Entrez ID	Gene Name
Nr1h2	ENSMUSG00000060601.6	Nr1h2

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Nr1h2	mm10_v2_chr7_-_44553901_44553955	0.51	3.0e-02	Click!

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Showing 1 to 20 of 114 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_53159885	6.411	ENSMUST00000030010.3	Abca1	ATP-binding cassette, sub-family A (ABC1), member 1
chr10_-_109823585	5.872	ENSMUST00000161582.1	Nav3	neuron navigator 3
chr11_+_84179792	4.009	ENSMUST00000137500.2 ENSMUST00000130012.2	Acaca	acetyl-Coenzyme A carboxylase alpha
chr6_+_90462562	3.719	ENSMUST00000032174.5	Klf15	Kruppel-like factor 15
chr3_-_148989316	3.150	ENSMUST00000098518.2	Lphn2	latrophilin 2
chr7_-_97417730	3.039	ENSMUST00000043077.7	Thrsp	thyroid hormone responsive
chr11_+_84179852	2.868	ENSMUST00000136463.2	Acaca	acetyl-Coenzyme A carboxylase alpha
chr7_-_27446599	2.422	ENSMUST00000011895.7	Sptbn4	spectrin beta, non-erythrocytic 4
chr5_-_100159261	2.324	ENSMUST00000139520.1	Tmem150c	transmembrane protein 150C
chr3_+_62419668	2.233	ENSMUST00000161057.1	Arhgef26	Rho guanine nucleotide exchange factor (GEF) 26
chr8_-_84773381	2.175	ENSMUST00000109764.1	Nfix	nuclear factor I/X
chr5_-_124327883	2.136	ENSMUST00000031344.6	Mphosph9	M-phase phosphoprotein 9
chr8_+_14095849	1.935	ENSMUST00000152652.1 ENSMUST00000133298.1	Dlgap2	discs, large (Drosophila) homolog-associated protein 2
chr5_+_76840597	1.923	ENSMUST00000120639.2 ENSMUST00000163347.1 ENSMUST00000121851.1	C530008M17Rik	RIKEN cDNA C530008M17 gene
chr2_+_156421083	1.891	ENSMUST00000125153.2 ENSMUST00000103136.1 ENSMUST00000109577.2	Epb4.1l1	erythrocyte protein band 4.1-like 1
chr11_-_30025915	1.848	ENSMUST00000058902.5	Eml6	echinoderm microtubule associated protein like 6
chr13_-_12461432	1.833	ENSMUST00000143693.1 ENSMUST00000144283.1 ENSMUST00000099820.3 ENSMUST00000135166.1	Lgals8	lectin, galactose binding, soluble 8
chr4_-_141538434	1.765	ENSMUST00000078886.3	Spen	SPEN homolog, transcriptional regulator (Drosophila)
chr5_-_136565432	1.745	ENSMUST00000176172.1	Cux1	cut-like homeobox 1
chr4_-_141538562	1.737	ENSMUST00000105786.2	Spen	SPEN homolog, transcriptional regulator (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 58 entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	6.9	GO:0044268	multicellular organismal protein metabolic process(GO:0044268)
1.6	6.4	GO:0055099	response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
0.2	3.7	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	3.1	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866)
0.0	2.7	GO:0010508	positive regulation of autophagy(GO:0010508)
0.4	2.4	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	2.3	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.1	2.2	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1	2.2	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	1.9	GO:0007270	neuron-neuron synaptic transmission(GO:0007270)
0.3	1.8	GO:0002317	plasma cell differentiation(GO:0002317)
0.2	1.7	GO:0006013	mannose metabolic process(GO:0006013)
0.1	1.7	GO:0007141	male meiosis I(GO:0007141)
0.0	1.7	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	1.7	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1	1.6	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.5	1.5	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.2	1.4	GO:0032196	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.2	1.4	GO:0006265	DNA topological change(GO:0006265)
0.1	1.4	GO:2000671	regulation of motor neuron apoptotic process(GO:2000671)

Gene overrepresentation in cellular_component category:

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Showing 1 to 20 of 20 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.4	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	5.9	GO:0001650	fibrillar center(GO:0001650)
0.0	3.5	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	3.3	GO:0005776	autophagosome(GO:0005776)
0.4	2.4	GO:0008091	spectrin(GO:0008091)
0.3	1.7	GO:0001533	cornified envelope(GO:0001533)
0.0	1.7	GO:0030173	integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1	1.6	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.2	1.5	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	1.2	GO:0005814	centriole(GO:0005814)
0.3	1.1	GO:1990769	proximal neuron projection(GO:1990769)
0.1	1.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	1.1	GO:0043196	varicosity(GO:0043196)
0.2	1.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.9	GO:0042382	paraspeckles(GO:0042382)
0.1	0.8	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.0	0.8	GO:0035097	histone methyltransferase complex(GO:0035097)
0.2	0.7	GO:0097447	dendritic tree(GO:0097447)
0.1	0.6	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.5	GO:0032593	insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular_function category:

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Showing 1 to 20 of 41 entries

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	6.9	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
2.1	6.4	GO:0030226	apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0	3.3	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	3.0	GO:0008017	microtubule binding(GO:0008017)
0.1	2.4	GO:0030506	ankyrin binding(GO:0030506)
0.0	2.3	GO:0019905	syntaxin binding(GO:0019905)
0.2	1.7	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1	1.7	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	1.7	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	1.7	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	1.6	GO:0032452	histone demethylase activity(GO:0032452)
0.2	1.5	GO:0008556	sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0	1.5	GO:0043130	ubiquitin binding(GO:0043130)
0.4	1.4	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
0.3	1.4	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.3	1.4	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	1.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	1.3	GO:0051213	dioxygenase activity(GO:0051213)
0.3	1.2	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1	1.2	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)

Gene overrepresentation in C2:CP category:

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Showing 1 to 10 of 10 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.5	PID_RXR_VDR_PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	2.8	PID_HES_HEY_PATHWAY	Notch-mediated HES/HEY network
0.0	1.8	PID_ARF6_TRAFFICKING_PATHWAY	Arf6 trafficking events
0.0	1.8	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	1.4	PID_ANTHRAX_PATHWAY	Cellular roles of Anthrax toxin
0.1	1.0	SA_FAS_SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.9	PID_INSULIN_PATHWAY	Insulin Pathway
0.0	0.8	PID_VEGFR1_2_PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.7	PID_HNF3B_PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.6	PID_IL6_7_PATHWAY	IL6-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 15 of 15 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	6.4	REACTOME_HDL_MEDIATED_LIPID_TRANSPORT	Genes involved in HDL-mediated lipid transport
0.2	5.4	REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.1	2.4	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.7	REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	1.5	REACTOME_BASIGIN_INTERACTIONS	Genes involved in Basigin interactions
0.1	1.4	REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	1.1	REACTOME_GLYCOSPHINGOLIPID_METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	1.0	REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.7	REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.6	REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.6	REACTOME_REGULATION_OF_KIT_SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.5	REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.5	REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.4	REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)