Motif ID: Nr3c2

Z-value: 0.888


Transcription factors associated with Nr3c2:

Gene SymbolEntrez IDGene Name
Nr3c2 ENSMUSG00000031618.7 Nr3c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c2mm10_v2_chr8_+_76902277_76902476-0.635.5e-03Click!


Activity profile for motif Nr3c2.

activity profile for motif Nr3c2


Sorted Z-values histogram for motif Nr3c2

Sorted Z-values for motif Nr3c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr3c2

PNG image of the network

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Top targets:


Showing 1 to 20 of 31 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_123366921 7.144 ENSMUST00000038863.7
 Lars2
leucyl-tRNA synthetase, mitochondrial
chr3_-_95904683 4.559 ENSMUST00000147962.1
ENSMUST00000036181.8
 Car14

carbonic anhydrase 14

chr4_-_149137536 2.606 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
 Apitd1



apoptosis-inducing, TAF9-like domain 1



chr2_+_172472512 2.064 ENSMUST00000029007.2
 Fam209
family with sequence similarity 209
chr14_-_8309770 1.942 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
 Fam107a


family with sequence similarity 107, member A


chr8_+_94179089 1.484 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr13_+_99100698 1.300 ENSMUST00000181742.1
 Gm807
predicted gene 807
chr4_-_9643638 1.286 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
 Asph




aspartate-beta-hydroxylase




chr15_-_97020322 1.272 ENSMUST00000166223.1
 Slc38a4
solute carrier family 38, member 4
chr1_-_171240055 1.242 ENSMUST00000131286.1
 Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr10_+_128225830 1.143 ENSMUST00000026455.7
 Mip
major intrinsic protein of eye lens fiber
chr6_-_6882068 1.080 ENSMUST00000142635.1
ENSMUST00000052609.8
 Dlx5

distal-less homeobox 5

chr1_-_74935549 1.014 ENSMUST00000094844.3
 Ccdc108
coiled-coil domain containing 108
chr14_+_70530819 0.995 ENSMUST00000047331.6
 Lgi3
leucine-rich repeat LGI family, member 3
chr11_+_101448403 0.862 ENSMUST00000010502.6
 Ifi35
interferon-induced protein 35
chr16_+_38346986 0.759 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
 Cox17

Gm21987
cytochrome c oxidase assembly protein 17

predicted gene 21987
chr16_-_96192222 0.731 ENSMUST00000113804.1
ENSMUST00000054855.7
 Lca5l

Leber congenital amaurosis 5-like

chr10_+_26822560 0.712 ENSMUST00000135866.1
 Arhgap18
Rho GTPase activating protein 18
chr8_+_71406003 0.620 ENSMUST00000119976.1
ENSMUST00000120725.1
 Ankle1

ankyrin repeat and LEM domain containing 1

chr3_-_88739692 0.592 ENSMUST00000090946.2
 Gm10253
predicted gene 10253

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.6 4.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 1.5 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.4 1.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 1.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.2 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.4 1.1 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.4 1.1 GO:0060166 olfactory pit development(GO:0060166)
0.2 1.1 GO:0032782 bile acid secretion(GO:0032782)
0.3 0.8 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.2 0.6 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.5 GO:0002076 osteoblast development(GO:0002076)
0.1 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.2 GO:0006014 D-ribose metabolic process(GO:0006014)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.2 GO:0005921 gap junction(GO:0005921)
0.0 1.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 7.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.4 4.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.5 GO:0005507 copper ion binding(GO:0005507)
0.0 1.3 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 1.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 1.2 GO:0048038 quinone binding(GO:0048038)
0.4 1.1 GO:0031403 lithium ion binding(GO:0031403)
0.1 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.8 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.3 GO:0003796 lysozyme activity(GO:0003796)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.2 PID_P73PATHWAY p73 transcription factor network
0.0 1.1 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 7.1 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.6 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.3 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.2 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 1.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.1 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.9 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import